Ligand ID: W9T


Drugbank ID:
DB00581
(Lactulose)


Indication:
For the treatment of constipation and hepatic encephalopathy.

Get human targets for W9T in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'W9T' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.73A17.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 8
ASN B1187
ASN B1192
GLU B1188
ARG E1185
1.58A20.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.74A19.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
ASP A  38
GLY B 447
TYR A  41
GLN A  42
1.40A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 5
ASP A  38
GLY B 447
TYR A  41
GLN A  42
1.32A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.73A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
ASP D  38
GLY F 447
TYR D  41
1.09A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 5
ASP D  38
GLY F 447
TYR D  41
GLN D  42
1.20A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
ASP D  38
GLY F 447
TYR D  41
GLN D  42
1.19A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR C 292
ASN C 203
GLY C 109
ILE C 106
1.69A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.78A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR D 292
ASN D 203
GLY D 109
ILE D 106
1.72A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.73A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ASN A 416
CYH A 842
GLY A 841
ILE A 548
1.72A18.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
ASP A 364
VAL A 362
GLY A 526
TYR A 365
1.77A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
ASP B1041
GLU B 725
GLY B1044
1.68A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN B  99
ARG B 190
HIS B 207
ASN B 121
1.75A7.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
ASP C 364
VAL C 362
GLY C 526
TYR C 365
1.79A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
THR B 141
GLY B 114
ASP B 144
ILE A  94
1.49A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
THR A  84
ASN A  83
ASP A 125
ILE A 144
1.58A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w02 NSP3
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.11A18.06
None
None
None
APR  B 201 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6949
CYH A6952
GLY A6953
ILE A6967
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6856
ASN A7008
GLY A6963
ILE A7005
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ASN A  51
ARG A 188
ASN A  53
ARG A  40
1.66A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w6y NSP3
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w6y NSP3
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.08A
None
None
None
AMP  A 201 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASP B 105
GLU B 104
GLY B 103
LEU B 108
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
CYH B4327
CYH B4343
ASP B4344
ILE B4308
1.49A14.35
 ZN  B4401 ( 2.2A)
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP16
(SARS-CoV-2)		4 / 6
THR A6949
CYH A6952
GLY A6953
ILE A6967
1.65A15.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
CYH D4327
CYH D4343
ASP D4344
ILE D4308
1.38A14.35
 ZN  D4401 ( 2.2A)
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.68A14.35
None
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP16
(SARS-CoV-2)		4 / 6
THR C6949
CYH C6952
GLY C6953
ILE C6967
1.65A15.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.69A14.35
None
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.67A14.35
None
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.68A14.35
None
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY C 100
LEU C 290
TYR C 283
GLU C 280
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY C 100
LEU C 290
TYR C 283
GLU C 280
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
GLY C 100
LEU C 290
TYR C 283
GLU C 280
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASP A 105
GLU A 104
GLY A 103
LEU A 108
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wcf NSP3
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.10A
None
None
MES  A 202 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wen NSP3
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wey NSP3
(SARS-CoV-2)		4 / 6
THR A 261
ASN A 258
GLY A 255
ILE A 227
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASP A 309
GLU A 308
GLY A 307
LEU A 312
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASP A 309
GLU A 308
GLY A 307
LEU A 312
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASP A 309
GLU A 308
GLY A 307
LEU A 312
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.67A
None
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.67A
None
ZN  D4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.68A14.35
None
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6949
CYH A6952
GLY A6953
ILE A6967
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
CYH D4327
CYH D4343
ASP D4344
ILE D4308
1.43A14.35
 ZN  D4401 (-2.2A)
ZN  D4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.68A14.35
None
ZN  D4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt NSP10
(SARS-CoV-2)		4 / 6
CYH B4327
CYH B4343
ASP B4344
ILE B4308
1.43A14.35
 ZN  B4401 (-2.2A)
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR C6949
CYH C6952
GLY C6953
ILE C6967
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR C6949
CYH C6952
GLY C6953
ILE C6967
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.66A
None
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.67A
None
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN D4338
CYH D4343
ASP D4344
ILE D4308
1.68A14.35
None
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
CYH B4327
CYH B4343
ASP B4344
ILE B4308
1.47A14.35
 ZN  B4401 ( 2.2A)
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR A6949
CYH A6952
GLY A6953
ILE A6967
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
CYH D4327
CYH D4343
ASP D4344
ILE D4308
1.41A14.35
 ZN  D4401 ( 2.2A)
ZN  D4401 ( 2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.67A14.35
None
ZN  B4401 ( 2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
THR A  84
ASN A  83
ASP A 125
ILE A 144
1.58A20.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
THR B 145
ASN B 178
GLY B 157
ILE B  72
1.63A
ACT  B 408 (-4.0A)
ACT  B 407 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
THR A 145
ASN A 178
GLY A 157
ILE A  72
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ASN B  74
GLY B  77
ASP B  79
ILE B  80
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
THR A  84
ASN A  83
ASP A 125
ILE A 144
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR D 149
ASN D 117
ASP A  22
ILE A  23
1.37A
None
None
APR  A 201 (-4.0A)
APR  A 201 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR C  57
ASN C  54
GLY C  51
ILE C  23
1.07A
None
None
None
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR B 149
ASN B 117
ASP C  22
ILE C  23
1.38A
None
None
APR  C 201 (-3.7A)
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.06A
None
None
None
APR  A 201 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR D 149
ASN D 117
ASP A  22
ILE A  23
1.38A18.81
None
None
APR  A 201 (-4.0A)
APR  A 201 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.11A
None
None
None
APR  B 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR B 149
ASN B 117
ASP C  22
ILE C  23
1.39A18.81
None
None
APR  C 201 (-3.7A)
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR D  57
ASN D  54
GLY D  51
ILE D  23
1.11A
None
None
None
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6949
CYH A6952
GLY A6953
ILE A6967
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6856
ASN A7008
GLY A6963
ILE A7005
1.78A
8NK  A7103 (-2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.62A14.35
None
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
CYH B4327
CYH B4343
ASP B4344
ILE B4308
1.33A14.35
 ZN  B4401 (-2.2A)
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
ASN B4338
CYH B4343
ASP B4344
ILE B4308
1.61A
None
ZN  B4401 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLU A 161
GLY A 160
LEU A 162
TYR A 112
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLU A 161
GLY A 160
LEU A 162
TYR A 112
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLY A 100
LEU A 290
TYR A 283
GLU A 280
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
GLU A 161
GLY A 160
LEU A 162
TYR A 112
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
CYH A 192
THR A 191
CYH A 224
GLY A 227
1.80A21.91
 ZN  A 501 (-2.3A)
ZN  A 501 ( 4.7A)
ZN  A 501 (-2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6xez NSP13
(SARS-CoV-2)		4 / 6
THR E 188
GLY E 222
ASP E 223
ILE E 195
1.48A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.74A17.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN A  51
ARG A 188
ASN A  53
ARG A  40
1.72A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 496
LEU E 452
TYR E 453
GLU B  16
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 496
LEU E 452
TYR E 453
GLU B  16
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 496
LEU E 452
TYR E 453
GLU B  16
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.71A
None
PEG  A 405 ( 4.9A)
PEG  A 405 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR E  57
ASN E  54
GLY E  51
ILE E  23
1.11A
None
None
None
EDO  E 205 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR C  57
ASN C  54
GLY C  51
ILE C  23
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR D  57
ASN D  54
GLY D  51
ILE D  23
1.09A
None
None
None
EDO  D 208 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.08A
None
None
None
APR  B 201 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR E  57
ASN E  54
GLY E  51
ILE E  23
1.09A
None
None
None
APR  E 201 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR D  57
ASN D  54
GLY D  51
ILE D  23
1.09A
None
None
None
APR  D 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR C  57
ASN C  54
GLY C  51
ILE C  23
1.08A
None
None
None
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.08A
None
None
None
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR B  57
ASN B  54
GLY B  51
ILE B  23
1.10A
None
None
None
EDO  B 202 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR A  57
ASN A  54
GLY A  51
ILE A  23
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
THR C  57
ASN C  54
GLY C  51
ILE C  23
1.08A
None
None
None
EDO  C 206 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		7btf NSP12
(SARS-CoV-2)		4 / 6
CYH A 645
THR A 644
CYH A 487
GLY A 486
1.54A18.15
 ZN  A1002 (-2.7A)
None
ZN  A1002 (-2.7A)
ZN  A1002 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7btf NSP12
(SARS-CoV-2)		4 / 6
ASN A 416
CYH A 842
GLY A 841
ILE A 548
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
THR A 292
ASN A 203
GLY A 109
ILE A 106
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
CYH D 142
THR D 141
GLY D 144
ASP D 143
1.53A17.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A 416
CYH A 842
GLY A 841
ILE A 548
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
CYH A 645
THR A 644
CYH A 487
GLY A 486
1.45A17.77
 ZN  A1002 (-2.4A)
None
ZN  A1002 (-2.3A)
ZN  A1002 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
THR D 148
CYH D 142
GLY D 144
ILE D 156
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
CYH A 645
THR A 643
CYH A 487
GLY A 486
1.64A17.77
 ZN  A1002 (-2.4A)
None
ZN  A1002 (-2.3A)
ZN  A1002 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		7bv2 NSP12
(SARS-CoV-2)		4 / 5
ASP A 761
VAL A 763
GLY A 616
ASP A 618
1.49A17.77
 MG  A1005 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ASN A 416
CYH A 842
GLY A 841
ILE A 548
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
CYH A 645
THR A 644
CYH A 487
GLY A 486
1.51A17.77
 ZN  A1002 (-2.6A)
None
ZN  A1002 (-2.3A)
ZN  A1002 ( 4.5A)