Ligand ID: SWF


Drugbank ID:
DB00682
(Warfarin)


Indication:
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.

Get human targets for SWF in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'SWF' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE C 923
PHE C 927
ALA C 924
ASN C 928
LEU A 922
1.51A18.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
PHE D 970
LEU F 977
LEU E1166
LEU F 966
PHE F 970
1.39A18.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 11
ALA E 942
LEU E 945
LEU F1186
SER D 940
ALA D 942
1.25A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.75A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.74A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.76A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		5 / 12
ILE E 358
PHE E 515
ALA E 397
LEU E 368
LEU E 387
1.42A17.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.75A21.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.78A21.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.73A21.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.75A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C 272
ALA C 234
LEU C 268
THR C 226
LEU C 227
1.70A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C 253
ALA C 206
LEU C 250
LEU C 268
LEU C 220
1.74A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 253
ALA B 210
PHE B   3
THR B 201
LEU B 268
1.72A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.77A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 230
ALA A 234
LEU A 272
LEU A 268
LEU A 208
1.79A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE B 230
ALA B 234
LEU B 272
LEU B 268
LEU B 208
1.75A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 253
ALA B 210
PHE B   3
THR B 201
LEU B 268
1.70A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.77A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.78A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ALA A 685
LEU A 575
SER A 578
ILE A 579
ALA A 580
1.38A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU D  95
LEU C  56
LEU C  59
ILE C  68
ALA D 110
1.51A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.75A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
ALA A 639
LEU A 636
LEU A 655
LEU A 351
1.37A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 862
THR A 870
LEU A 869
PRO A 868
PHE A 881
1.47A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 142
LEU A 131
LEU A 247
ILE A 171
1.78A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ARG A 181
ALA A 185
LEU A 241
LEU A 212
LEU A 119
1.69A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ALA C  65
LEU C  59
LEU C  71
ILE D 107
ALA D 110
1.41A10.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.61A18.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ALA A 526
LEU A 527
LEU A 372
SER A 561
ILE A 562
1.66A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 862
THR A 870
LEU A 869
PRO A 868
PHE A 881
1.48A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 131
LEU A 142
LEU A 146
ILE A 171
1.26A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE C  49
LEU C  35
THR C   9
LEU C  56
LEU D  98
1.63A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.58A18.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 358
PHE C 515
ALA C 397
LEU C 368
LEU C 387
1.41A17.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6vxs NSP3
(SARS-CoV-2)		5 / 11
PHE B 168
LEU B 153
LEU B 164
LEU B 160
ALA B 129
1.75A
None
None
None
SO4  B 204 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 358
PHE A 515
ALA A 397
LEU A 368
LEU A 387
1.36A17.46
None
None
None
NAG  A1307 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 358
PHE A 515
ALA A 397
LEU A 368
LEU A 387
1.33A17.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
ALA C 944
LEU C 945
LEU C 938
LEU C 821
SER C 816
1.48A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w4h NSP16
(SARS-CoV-2)		6 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
THR A6918
LEU A6909
1.58A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7073
PHE A6985
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6959
ALA A6960
THR A6891
PRO A6860
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ALA A6966
LEU A6852
LEU A6924
LEU A6887
ALA A6858
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		6 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
THR A6918
LEU A6909
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
PHE A6901
THR A6918
LEU A6909
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7010
PHE A6985
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 11
PHE B 116
ALA B 124
LEU B 153
LEU B 140
ALA B 129
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.73A
None
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ALA A6966
LEU A6852
LEU A6924
LEU A6887
ALA A6858
1.68A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
LEU A6909
1.55A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6892
ASN C6862
LEU C7050
PRO C6888
LEU C7052
1.75A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7010
PHE A6985
1.78A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6959
ALA A6960
THR A6891
PRO A6860
1.70A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE C7005
PHE C6985
ASN C7008
LEU C6924
LEU C6959
1.80A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6892
ASN C6862
LEU C7050
PRO C6888
LEU C7052
1.72A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ALA C6966
LEU C6852
LEU C6924
LEU C6887
ALA C6858
1.68A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7073
PHE C6985
1.70A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7010
PHE C6985
1.78A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
LEU C6893
THR C6918
LEU C6909
1.54A15.57
None
None
None
FMT  C7113 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
PHE C6901
LEU C6893
LEU C6909
1.58A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
LEU A6893
THR A6918
LEU A6909
1.51A15.57
None
None
None
FMT  A7109 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7073
PHE A6985
1.69A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 118
ALA B 114
LEU B 152
LEU B 172
PHE B 147
1.76A
None
CL  B 502 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE C 147
ALA C 145
LEU C  87
LEU C 113
LEU C 172
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA C 116
LEU C 120
LEU C 172
LEU C 132
ALA C 176
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 118
ALA C 114
LEU C 152
LEU C 172
PHE C 147
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 118
ALA A 114
LEU A 152
LEU A 172
PHE A 147
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 118
ALA C 114
LEU C 152
LEU C 172
PHE C 147
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 118
ALA B 114
LEU B 152
LEU B 172
PHE B 147
1.74A
None
CL  B 502 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA A 116
LEU A 120
LEU A 172
LEU A 132
ALA A 176
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 118
ALA A 114
LEU A 152
LEU A 172
PHE A 147
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 178
LEU B 125
ASN B 177
LEU B 132
PRO B 129
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wcf NSP3
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wcf NSP3
(SARS-CoV-2)		5 / 11
ALA A 154
LEU A 153
LEU A 140
SER A 139
ALA A 129
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wey NSP3
(SARS-CoV-2)		5 / 11
PHE A 320
ALA A 328
LEU A 357
LEU A 344
ALA A 333
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE A  49
LEU A  35
THR A   9
LEU A  56
LEU B  98
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE B  92
LEU A  13
LEU A  55
SER A  54
ILE B 119
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 11
ALA A  65
LEU A  59
LEU A  56
ILE B 106
ALA B 110
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE B 120
ALA B 150
LEU A  60
PRO B 116
LEU B 117
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU B  95
LEU A  56
LEU A  59
ILE A  68
ALA B 110
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7010
PHE C6985
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7073
PHE A6985
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
LEU A6893
THR A6918
LEU A6909
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7010
PHE A6985
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7073
PHE C6985
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6959
ALA A6960
THR A6891
PRO A6860
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
PHE C6901
LEU C6893
LEU C6909
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6959
ALA C6960
THR C6891
PRO C6860
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ALA C6966
LEU C6852
LEU C6924
LEU C6887
ALA C6858
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
LEU C6893
THR C6918
LEU C6909
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ALA A6966
LEU A6852
LEU A6924
LEU A6887
ALA A6858
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
LEU A6909
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ALA A6966
LEU A6852
LEU A6924
LEU A6887
ALA A6858
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7073
PHE A6985
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
PHE C6901
LEU C6893
LEU C6909
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6868
ALA C6870
LEU C6893
THR C6918
LEU C6909
1.54A
None
None
None
FMT  C7108 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6959
ALA A6960
THR A6891
PRO A6860
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
LEU A6893
THR A6918
LEU A6909
1.52A
None
None
None
FMT  A7108 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
LEU A6909
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE C7005
PHE C6985
ASN C7008
LEU C6924
LEU C6959
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ALA C6966
LEU C6852
LEU C6924
LEU C6887
ALA C6858
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7010
PHE A6985
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7010
PHE C6985
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE C7079
LEU C6857
ALA C6858
LEU C7073
PHE C6985
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B  44
ALA B  55
LEU B  58
ILE B  86
ALA B  95
1.79A
TRS  B 402 (-4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B  44
ALA B  55
LEU B  50
LEU B  58
ALA B  95
1.73A
TRS  B 402 (-4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A  44
ALA A  55
LEU A  58
ILE A  86
ALA A  95
1.80A
TRS  A 402 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A  44
ALA A  55
LEU A  50
LEU A  58
ALA A  95
1.73A
TRS  A 402 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ALA A 161
PHE A 177
LEU A  73
THR A 193
PRO A 158
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE D 156
LEU D 160
LEU D 164
SER D 139
ALA D 129
1.64A
APR  D 201 (-4.5A)
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE B 116
ALA B 124
LEU B 153
LEU B 140
ALA B 129
1.74A
None
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE C 116
ALA C 124
LEU C 153
LEU C 140
ALA C 129
1.74A
None
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE C 156
LEU C 160
LEU C 164
SER C 139
ALA C 129
1.65A
APR  C 201 (-4.7A)
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE D 116
ALA D 124
LEU D 153
LEU D 140
ALA D 129
1.77A
None
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 156
LEU A 160
LEU A 164
SER A 139
ALA A 129
1.65A
APR  A 201 (-4.7A)
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE B 156
LEU B 160
LEU B 164
SER B 139
ALA B 129
1.63A
APR  B 201 (-4.6A)
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.76A
None
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
LEU A6893
THR A6918
LEU A6909
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6959
ALA A6960
THR A6891
PRO A6860
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ALA A6966
LEU A6852
LEU A6924
LEU A6887
ALA A6858
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
TRP A6987
LEU A6857
LEU A6852
ILE A6926
ALA A6966
1.68A
8NK  A7103 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7010
PHE A6985
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6868
ALA A6870
PHE A6901
LEU A6893
LEU A6909
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7079
LEU A6857
ALA A6858
LEU A7073
PHE A6985
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE D  92
LEU C  13
LEU C  55
SER C  54
ILE D 119
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE B  92
LEU A  13
LEU A  55
SER A  54
ILE B 119
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE C  49
LEU C  35
THR C   9
LEU C  56
LEU D  98
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE A  49
LEU A  35
THR A   9
LEU A  56
LEU B  98
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE B 120
ALA B 150
LEU A  60
PRO B 116
LEU B 117
1.62A
None
EDO  B 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 230
LEU A 208
LEU A 205
LEU A 250
SER A 254
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
PHE A 147
ALA A 145
LEU A  87
LEU A 113
LEU A 172
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
ARG A 138
PHE A 147
LEU A 152
ALA A 149
THR A 102
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
ALA A 116
LEU A 120
LEU A 172
LEU A 132
ALA A 176
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A 118
ALA A 114
LEU A 152
LEU A 172
PHE A 147
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
ARG A 138
PHE A 147
LEU A 152
ALA A 149
THR A 102
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
ALA A  86
LEU A 152
LEU A 113
SER A 111
ILE A 104
1.62A
None
None
None
PO4  A 502 (-2.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.79A16.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE B 106
ALA B 102
ASN B 104
THR A   9
LEU B  91
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE C  49
LEU C  35
THR C   9
LEU C  56
LEU D  98
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE A  49
LEU A  35
THR A   9
LEU A  56
LEU B  98
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
ALA B 110
LEU A  71
LEU A  60
LEU A  56
ALA A  65
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
PHE D  92
LEU C  13
LEU C  55
SER C  54
ILE D 119
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
ALA A  65
LEU A  59
LEU A  56
ILE B 106
ALA B 110
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE E 358
PHE E 515
ALA E 397
LEU E 368
LEU E 387
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 358
PHE A 515
ALA A 397
LEU A 368
LEU A 387
1.48A
None
None
None
None
DMS  A 905 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE E 358
PHE E 515
ALA E 397
LEU E 368
LEU E 387
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 219
ALA A 210
PHE A   3
LEU A 253
LEU A 271
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE E 358
PHE E 515
ALA E 397
LEU E 368
LEU E 387
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 358
PHE A 515
ALA A 397
LEU A 368
LEU A 387
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 219
ALA A 210
PHE A   3
LEU A 253
LEU A 271
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 230
LEU A 208
LEU A 205
LEU A 250
SER A 254
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE D 116
ALA D 124
LEU D 153
LEU D 140
ALA D 129
1.75A
None
None
None
None
EDO  D 205 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B 116
ALA B 124
LEU B 153
LEU B 140
ALA B 129
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE E 116
ALA E 124
LEU E 153
LEU E 140
ALA E 129
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C 116
ALA C 124
LEU C 153
LEU C 140
ALA C 129
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE E 116
ALA E 124
LEU E 153
LEU E 140
ALA E 129
1.76A
None
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C 116
ALA C 124
LEU C 153
LEU C 140
ALA C 129
1.79A
None
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.78A
None
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE D 116
ALA D 124
LEU D 153
LEU D 140
ALA D 129
1.78A
None
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B 116
ALA B 124
LEU B 153
LEU B 140
ALA B 129
1.79A
None
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B 116
ALA B 124
LEU B 153
LEU B 140
ALA B 129
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE A 116
ALA A 124
LEU A 153
LEU A 140
ALA A 129
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C 116
ALA C 124
LEU C 153
LEU C 140
ALA C 129
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 131
LEU A 142
LEU A 146
ILE A 171
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 526
LEU A 527
LEU A 372
SER A 561
ILE A 562
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 142
LEU A 131
LEU A 247
ILE A 171
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 685
LEU A 575
SER A 578
ILE A 579
ALA A 580
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
ALA A 639
LEU A 636
LEU A 655
LEU A 351
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7btf NSP12
(SARS-CoV-2)		5 / 12
ARG A 181
ALA A 185
LEU A 241
LEU A 212
LEU A 119
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE C  49
LEU C  35
THR C   9
LEU C  56
LEU D  98
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 206
LEU A 250
LEU A 268
LEU A 220
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 253
ALA A 210
PHE A   3
THR A 201
LEU A 268
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ALA A 685
LEU A 575
SER A 578
ILE A 579
ALA A 580
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 660
PHE A 348
LEU A 329
PRO A 328
LEU B 117
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU D  95
LEU C  13
LEU C  59
SER C  57
ILE D 106
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 131
LEU A 142
LEU A 146
ILE A 171
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
ALA A 639
LEU A 636
LEU A 655
LEU A 351
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE C  49
LEU C  35
THR C   9
LEU C  56
LEU D  98
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
PHE A 192
ALA A 195
LEU A  89
PRO A 232
PHE A 222
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ARG A 181
ALA A 185
LEU A 207
LEU A 212
LEU A 119
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 862
THR A 870
LEU A 869
PRO A 868
PHE A 881
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE D 106
ALA D 102
ASN D 104
THR C   9
LEU D  91
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.71A
None
None
None
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ALA A 130
LEU A 131
LEU A 142
LEU A 146
ILE A 171
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ARG A 181
ALA A 185
LEU A 241
LEU A 212
LEU A 119
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ALA A 685
LEU A 575
SER A 578
ILE A 579
ALA A 580
1.49A
 A  T  11 ( 4.7A)
None
None
None
A  T  13 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
ALA A 382
ASN B 118
LEU A 388
PHE A 396
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 862
THR A 870
LEU A 869
PRO A 868
PHE A 881
1.58A
 U  P  17 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
TRP A 509
LEU A 372
LEU A 527
ILE A 536
ALA A 376
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
ALA A 639
LEU A 636
LEU A 655
LEU A 351
1.48A
None