Ligand ID: SNP


Drugbank ID:
DB00571
(Propranolol)


Indication:
For the prophylaxis of migraine.

Get human targets for SNP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'SNP' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A  71
SER A 121
GLY A 120
VAL A  18
1.71A17.96
DMS  A 403 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.70A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.09A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 281
THR A 257
ILE A 259
LEU A 205
1.53A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 281
ALA A 211
ILE A 213
ILE A 259
1.55A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 253
ALA A 210
ILE A 213
PHE A 291
1.65A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 281
LEU A 282
ILE A 213
PHE A 219
1.54A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6lu7 MAIN PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.05A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 7
ILE F 931
ILE E 934
SER F 929
PHE F 927
LEU E 938
1.74A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 8
ILE C 931
LEU C1197
ILE C1198
ILE A 923
SER A 929
1.50A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.71A21.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.14A21.24

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.71A19.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.14A19.35

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.16A19.55

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLN C 299
PHE C 305
SER A 123
GLY A 124
1.51A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ILE B 200
ILE B 106
THR B 135
ILE B 136
1.18A19.55

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLY C  71
SER C 121
GLY C 120
VAL C  18
1.57A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
PHE C 305
SER A 123
GLY A 124
VAL A 125
1.55A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLY D  71
SER D 121
GLY D 120
VAL D  18
1.56A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
ILE B 281
LEU B 282
ALA B 211
ILE B 213
PHE B 219
1.79A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ILE C 200
ILE C 106
THR C 135
ILE C 136
1.13A19.55

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
ILE C 281
LEU C 282
ALA C 211
ILE C 213
PHE C 219
1.76A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
ILE D 281
LEU D 282
ALA D 211
ILE D 213
PHE D 219
1.75A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
PHE D 305
SER B 123
GLY B 124
VAL B 125
1.58A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ILE D 200
ILE D 106
THR D 135
ILE D 136
1.11A19.55

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.71A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.14A19.55

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASP A 377
SER A 343
GLY A 345
VAL A 354
1.40A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 307
LEU A 351
ALA A 311
SER A 635
1.26A13.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLY A 559
SER A 682
GLY A 683
VAL A 560
1.41A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 536
ALA A 376
ILE A 539
SER A 343
1.20A13.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLN A 661
GLY A 559
SER A 681
GLY A 683
1.59A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m71 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE C  68
ALA D 110
ILE D 106
PHE D  92
1.26A16.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6m71 NSP12
(SARS-CoV-2)		4 / 5
PHE A 313
VAL A 182
PRO A 243
MET A 463
1.80A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLN A 210
GLY A 203
PHE A 222
VAL A 233
1.51A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 145
LEU A 142
ALA A 130
ILE A 244
0.97A13.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ILE A 466
ILE A 307
PHE A 313
LEU A 636
1.41A13.37

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ILE A 536
THR A 540
SER A 561
LEU A 663
1.39A13.37

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
PHE C 927
VAL C 911
MET C1050
VAL C 722
1.46A13.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 989
SER B 746
GLU B 748
THR A 547
ASP B 979
1.78A15.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN A1054
GLY A 885
PHE A 888
GLY A 880
1.20A13.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ALA A 713
ILE A 714
ILE A 712
ILE B 896
SER B 884
1.32A10.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ILE B 670
ILE B 664
ILE B 598
ILE B 692
PHE B 643
1.41A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASP C 614
GLY A 857
PHE C 592
VAL A 736
1.24A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
PHE B 906
VAL B1040
PRO B1069
VAL B 911
1.45A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
PHE C 906
VAL C1040
PRO C1069
VAL C 911
1.48A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ILE B 235
LEU B 117
ILE B 119
ILE B 203
PHE B  86
1.36A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASP B 614
GLY C 857
PHE B 592
VAL C 736
1.18A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR B 325
TYR B 179
GLN B 160
THR B 167
ASP B 273
1.61A21.04
None
None
EDO  B 407 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w02 NSP3
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  96
1.74A19.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
ILE C 402
SER C 349
PHE C 400
LEU C 455
1.15A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 434
ILE C 410
ILE C 402
SER C 375
1.40A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 402
ALA C 435
ILE C 434
PHE C 400
1.62A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
GLY C 431
PHE C 429
GLY C 381
VAL C 382
1.66A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 402
ALA C 435
ILE C 434
SER C 438
1.50A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w4h NSP16
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.05A24.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w4h NSP16
(SARS-CoV-2)		5 / 8
ILE A6969
LEU A7004
ILE A7005
ILE A6926
SER A6927
1.54A24.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.06A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
THR A6880
PHE A6868
LEU A6887
1.51A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6925
THR A6918
ILE A7088
LEU A6892
1.66A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A6925
SER A6927
LEU A6981
1.47A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7005
LEU A7004
ILE A6955
ILE A6951
1.60A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
THR A6915
PHE A6954
LEU A6898
1.59A21.43
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6967
ILE A6926
PHE A6868
1.46A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 NSP10
(SARS-CoV-2)		4 / 8
ILE B4352
ILE B4308
SER B4320
PHE B4321
1.56A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6951
ILE A6925
ILE A6866
SER A6896
1.59A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A7005
ILE A6925
ILE A6951
LEU A6959
1.76A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6978
ILE A6951
ILE A6925
ILE A6926
1.55A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6967
THR A6970
ILE A6969
SER A6973
1.34A21.43
None
KCX  A6935 (-3.2A)
None
EDO  A7102 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A7005
ILE A6967
SER A6927
1.60A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6955
ILE A6967
SER A6927
1.67A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A6955
THR A6949
LEU A6981
1.80A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7004
ILE A6967
ILE A6951
ILE A6955
1.47A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7079
LEU A7078
ILE A7069
ILE A7065
1.44A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.38A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6926
ILE A6967
PHE A6947
LEU A6848
1.76A21.43
None
None
EDO  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
GLY A6871
PHE A6901
SER A6896
GLY A6869
1.67A18.01
SAM  A7104 (-4.4A)
None
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7069
ILE A7065
ILE A7080
SER A7059
1.64A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6883
ILE A6926
ILE A6925
ILE A6866
1.55A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6955
ILE A6951
ILE A6967
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6969
LEU A7004
ILE A6955
PHE A6948
1.22A
None
None
None
EDO  A7102 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 NSP10
(SARS-CoV-2)		4 / 7
ILE B4352
ILE B4291
PHE B4321
LEU B4328
1.58A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6925
ILE A7088
PHE A6868
LEU A6892
1.56A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE A6969
LEU A7004
ILE A7005
ILE A6926
SER A6927
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASP A6928
GLY A6875
GLY A6871
VAL A6876
1.71A18.01
SAM  A7104 (-3.8A)
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 NSP10
(SARS-CoV-2)		4 / 7
ILE B4352
ILE B4308
SER B4320
PHE B4321
1.55A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
THR A6949
ILE A6951
LEU A6981
1.30A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6978
ILE A6951
ILE A6925
PHE A6985
1.35A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6951
ILE A6926
ILE A6866
LEU A6924
1.50A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6955
ILE A6967
PHE A6868
1.57A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASP A6873
GLY A6869
SER A6872
GLY A6871
1.76A18.01
None
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASP A6873
GLY A6879
SER A6872
VAL A6842
1.65A18.01
None
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6955
ILE A6951
ILE A6967
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6852
1.64A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7027
LEU A6820
ILE A6969
SER A7000
1.61A21.43
None
None
None
KCX  A6935 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7004
ALA A7002
ILE A6969
ILE A7027
1.58A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A6866
LEU A6924
1.64A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLN A 118
GLY A  97
GLY A  79
VAL A  96
1.75A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ILE A  23
LEU A 123
ALA A 124
ILE A  18
1.30A20.26
AMP  A 201 ( 4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY A  97
SER A  80
GLY A  79
VAL A  77
1.62A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w6y NSP3
(SARS-CoV-2)		4 / 8
LEU B 153
ALA B 124
ILE B  23
PHE B   6
1.63A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY B  97
SER B  80
GLY B  79
VAL B  77
1.64A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w6y NSP3
(SARS-CoV-2)		4 / 8
LEU A 153
ALA A 124
ILE A  23
PHE A   6
1.62A20.26
None
None
AMP  A 201 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.52A
None
MES  B 201 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY A  97
SER A 111
GLY A  78
VAL A  95
1.73A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLN B 118
GLY B  97
GLY B  78
VAL B  96
1.65A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  77
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.40A
None
MES  B 201 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLN A  62
GLY A  48
GLY A  51
VAL A  49
1.60A
None
AMP  A 201 ( 3.6A)
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ILE B  23
LEU B 123
ALA B 124
ILE B  18
1.30A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w6y NSP3
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  96
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7005
LEU A7004
ILE A6955
ILE A6951
1.53A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6955
ILE A6951
ILE A6967
1.05A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE B4352
ILE B4308
SER B4320
PHE B4321
1.54A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP A6904
GLY A6871
PHE A6901
SER A6903
1.67A17.27
None
SAM  A7102 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A7005
ILE A6925
ILE A6951
LEU A6959
1.78A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6926
ILE A6967
PHE A6947
LEU A6848
1.73A22.27
None
None
SAM  A7102 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE B4352
ILE B4291
PHE B4321
LEU B4328
1.56A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7080
ILE C7065
ILE C7069
SER C7071
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 8
LEU B4328
ALA B4276
ILE B4334
ILE D4334
1.54A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6926
ILE C6967
PHE C6947
LEU C6848
1.71A22.27
None
None
FMT  C7115 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6955
ILE A6967
PHE A6868
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP A6873
GLY A6879
SER A6872
VAL A6842
1.74A17.27
None
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE B4308
ILE B4352
SER B4320
LEU B4345
1.77A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6978
ILE C6951
ILE C6925
PHE C6985
1.38A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6969
LEU A7004
ILE A6955
PHE A6948
1.25A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6909
ILE A6866
SER A6903
PHE A6901
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7027
LEU C6820
ILE C6969
SER C7000
1.54A22.27
None
None
None
FMT  C7110 ( 2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C7004
ILE C6967
ILE C6951
ILE C6955
1.47A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6866
THR A6880
PHE A6868
LEU A6887
1.48A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 7
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.73A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6866
THR A6915
PHE A6954
LEU A6898
1.48A22.27
None
None
None
SAM  A7102 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.02A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6866
THR C6915
PHE C6954
LEU C6898
1.45A22.27
None
None
None
SAM  C7105 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6969
THR A6949
ILE A6951
LEU A6981
1.40A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6925
THR A6918
ILE A7088
LEU A6892
1.26A22.27
None
FMT  A7109 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6866
ILE C6967
PHE C6954
LEU C6848
1.40A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6925
THR C6918
ILE C7088
LEU C6892
1.25A22.27
None
FMT  C7113 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE B4352
THR B4309
ILE B4308
PHE B4321
1.68A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.39A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.03A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
GLY C6871
PHE C6901
SER C6896
GLY C6869
1.70A17.27
SAM  C7105 ( 4.2A)
None
None
SAM  C7105 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6959
ILE C6967
ILE C6926
PHE C6868
1.50A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6883
ILE C6926
ILE C6925
ILE C6866
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6951
ILE A6926
ILE A6866
LEU A6924
1.52A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6981
ILE C6955
ILE C6925
ILE C6967
1.64A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6866
ILE C6967
PHE C6954
LEU C6852
1.60A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 8
ILE C6866
ILE C6955
ILE C6967
SER C6927
PHE C6868
1.80A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7005
ILE C6951
ILE C6955
ILE C6925
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6925
ILE A7005
SER A6927
LEU A6852
1.80A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A7005
ILE A6967
SER A6927
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 8
ILE D4352
ILE D4308
SER D4320
PHE D4321
1.56A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6925
ILE A7088
PHE A6868
LEU A6892
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7017
SER A6943
PHE A6948
1.70A22.27
None
FMT  A7111 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 8
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.79A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
GLY A6871
PHE A6901
SER A6896
GLY A6869
1.70A17.27
SAM  A7102 ( 4.2A)
None
None
SAM  A7102 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 8
ILE B4352
ILE B4308
SER B4320
PHE B4321
1.54A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7069
ILE C7065
ILE C7080
SER C7059
1.47A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6959
ILE C6955
ILE C6951
ILE C6967
1.16A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6866
THR C6880
PHE C6868
LEU C6887
1.49A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE D4352
ILE D4291
PHE D4321
LEU D4328
1.56A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6951
ILE C6926
ILE C6866
LEU C6924
1.51A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP A6928
GLY A6875
GLY A6871
VAL A6876
1.71A17.27
SAM  A7102 ( 3.7A)
None
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7079
LEU C7078
ILE C7069
ILE C7065
1.39A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 8
LEU B4365
ALA B4277
ILE B4334
PHE D4272
1.52A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6959
ILE C6925
ILE C6967
ILE C6951
1.61A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7005
ILE A6925
ILE A6951
ILE A6955
1.54A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6978
ILE C6951
ILE C6925
ILE C6926
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7080
ILE A7065
ILE A7069
SER A7071
1.58A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE D4352
ILE D4308
SER D4320
PHE D4321
1.55A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C7005
ILE C6925
ILE C6951
LEU C6959
1.73A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 7
ILE C6866
ILE C6955
ILE C6967
SER C6927
PHE C6868
1.73A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6969
ILE C7017
SER C6943
PHE C6948
1.69A22.27
None
None
None
FMT  C7115 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6969
LEU C7004
ILE C6955
PHE C6948
1.26A22.27
None
None
None
FMT  C7115 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7079
LEU A7078
ILE A7069
ILE A7065
1.42A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C7004
ALA C7002
ILE C6969
ILE C7027
1.64A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.04A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 8
ILE C6969
LEU C7004
ILE C7005
ILE C6926
SER C6927
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.39A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6967
ILE A6926
PHE A6868
1.50A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP A6873
GLY A6869
SER A6872
GLY A6871
1.76A17.27
None
SAM  A7102 ( 3.8A)
SAM  A7102 ( 4.6A)
SAM  A7102 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7069
ILE A7065
ILE A7080
SER A7059
1.51A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6967
THR A6970
ILE A6969
SER A6973
1.34A22.27
None
FMT  A7103 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A6866
LEU A6924
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP C6928
GLY C6875
GLY C6871
VAL C6876
1.70A17.27
SAM  C7105 ( 3.7A)
None
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6969
ILE C7005
ILE C6926
SER C6927
1.38A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASP C6904
GLY C6871
PHE C6901
SER C6903
1.67A17.27
None
SAM  C7105 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6955
ILE C6926
ILE C6866
LEU C6924
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.03A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6848
ILE C7005
ILE C6967
SER C6927
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6951
THR C6970
ILE C6969
SER C6973
1.62A22.27
None
FMT  C7107 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6969
ILE C6955
ILE C6925
SER C6927
1.65A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A7004
ILE A6967
ILE A6951
ILE A6955
1.49A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A7004
ALA A7002
ILE A6969
ILE A7027
1.62A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6848
1.41A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE D4352
THR D4309
ILE D4308
PHE D4321
1.67A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7005
LEU C7004
ILE C6955
ILE C6951
1.62A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6978
ILE A6951
ILE A6925
PHE A6985
1.35A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6925
ILE C7088
PHE C6868
LEU C6892
1.65A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6883
ILE A6926
ILE A6925
ILE A6866
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7005
ILE C6925
ILE C6951
ILE C6955
1.60A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6955
ILE C6951
ILE C6967
1.23A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6852
1.59A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		5 / 8
ILE C6969
LEU C6978
ILE C6955
ILE C6925
SER C6927
1.80A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
LEU C6978
ILE C6969
PHE C6985
1.64A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6955
ILE A6951
ILE A6967
1.25A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7027
LEU A6820
ILE A6969
SER A7000
1.64A22.27
None
None
None
FMT  A7105 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6924
ILE C6955
ILE C6967
PHE C6868
1.57A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6967
THR C6970
ILE C6969
SER C6973
1.34A22.27
None
FMT  C7107 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
LEU C6978
ILE C7017
PHE C6985
1.63A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6969
THR C6949
ILE C6951
LEU C6981
1.56A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ILE C6925
ILE C7088
THR C6880
LEU C6909
1.50A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6978
ILE A6951
ILE A6925
ILE A6926
1.55A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w75 NSP10
(SARS-CoV-2)		4 / 7
ILE D4308
ILE D4352
SER D4320
LEU D4345
1.77A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6951
ILE A6925
ILE A6866
SER A6896
1.52A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE B 104
THR B 168
ILE B 151
LEU B 120
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE C 104
THR C 168
ILE C 151
LEU C 120
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE B 285
THR B 281
PHE B 258
LEU B 290
1.37A
 CL  B 502 (-4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 285
THR A 281
PHE A 258
LEU A 290
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
GLN A  -3
GLY A 104
GLY A 100
VAL A 102
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.39A
None
MES  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wcf NSP3
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  96
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.53A
None
MES  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
GLY A 282
SER A 332
GLY A 301
VAL A 300
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
GLY A 282
SER A 332
GLY A 301
VAL A 281
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wiq NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
ILE B 185
ILE B 132
LEU B 117
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE A  68
ALA B 110
ILE B 106
PHE B  92
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 106
LEU B 103
ALA B 102
SER A  54
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE F 337
LEU F 339
ILE F 357
PHE E 314
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE A 304
LEU A 291
ILE A 292
SER B 312
PHE B 315
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 304
ILE D 292
SER C 312
PHE C 315
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE F 304
LEU F 352
ILE F 357
PHE E 315
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE D 304
LEU D 352
ILE D 357
PHE C 315
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE B 304
LEU B 291
ILE B 292
SER A 312
PHE A 315
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE F 304
LEU F 291
ILE F 292
SER E 312
PHE E 315
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE D 304
LEU D 291
ILE D 292
SER C 312
PHE C 315
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE C 304
LEU C 291
ILE C 292
SER D 312
PHE D 315
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ILE E 304
LEU E 291
ILE E 292
SER F 312
PHE F 315
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE C 304
LEU C 352
ILE C 357
PHE D 315
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE A 304
LEU A 352
ILE A 357
PHE B 315
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE B 304
LEU B 352
ILE B 357
PHE A 315
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6955
ILE A6951
ILE A6967
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE C6925
THR C6918
ILE C7088
LEU C6892
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C6959
ILE C6955
ILE C6951
ILE C6967
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE C6866
ILE C6967
PHE C6954
LEU C6848
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6955
ILE C6951
ILE C6967
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6925
THR A6918
ILE A7088
LEU A6892
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
THR A6949
ILE A6951
LEU A6981
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE C6967
THR C6970
ILE C6969
SER C6973
1.35A
None
FMT  C7104 (-3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6967
THR A6970
ILE A6969
SER A6973
1.35A
None
FMT  A7103 (-3.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE C6969
LEU C6978
ILE C6955
ILE C6925
SER C6927
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 7
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE C6969
ILE C7005
ILE C6926
SER C6927
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE C6866
ILE C6955
ILE C6967
SER C6927
PHE C6868
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6848
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 7
ILE C6866
ILE C6955
ILE C6967
SER C6927
PHE C6868
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6955
ILE A6951
ILE A6967
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE C6969
LEU C7004
ILE C6925
ILE C6955
PHE C6948
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE C6866
ILE C6967
PHE C6954
LEU C6848
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6955
ILE A6951
ILE A6967
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		5 / 7
ILE C6866
ILE C6955
ILE C6967
SER C6927
PHE C6868
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		5 / 8
ILE A6969
LEU A7004
ILE A7005
ILE A6926
SER A6927
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		5 / 8
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6967
THR A6970
ILE A6969
SER A6973
1.35A
None
FMT  A7105 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6969
LEU C7004
ILE C6955
PHE C6948
1.26A
None
None
None
FMT  C7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE C6969
ILE C7005
ILE C6926
SER C6927
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6955
ILE C6951
ILE C6967
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6955
ILE A6951
ILE A6967
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE C6967
THR C6970
ILE C6969
SER C6973
1.35A
None
FMT  C7104 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU C6959
ILE C6955
ILE C6951
ILE C6967
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE C6955
ILE C6926
ILE C7005
PHE C6985
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6925
THR A6918
ILE A7088
LEU A6892
1.39A
None
FMT  A7108 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE C6925
THR C6918
ILE C7088
LEU C6892
1.35A
None
FMT  C7108 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6969
THR A6949
ILE A6951
LEU A6981
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		5 / 7
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wkq NSP16
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6848
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ASP B 297
GLN B 197
GLY B 254
VAL B 237
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE A 296
THR A 322
ILE A 328
LEU A 298
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B 223
LEU B 228
ILE B 307
ILE B 236
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B 116
ILE A 116
ILE A 108
ILE A  80
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B  72
THR B 322
ILE B 328
LEU B 298
1.42A
None
EDO  B 406 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B 307
ILE B 323
ILE B 296
PHE B 342
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B 253
LEU B 300
ILE B 212
PHE B 204
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE A 236
ILE A 296
ILE A 306
PHE A 233
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B 296
THR B 322
ILE B 328
LEU B 298
1.37A
None
EDO  B 406 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B 116
THR B  99
ILE B  80
PHE B 124
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 253
LEU A 300
ILE A 212
PHE A 204
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE A  86
ILE A  97
THR A 121
ILE A  80
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B  86
ILE B  97
THR B 121
ILE B  80
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B 236
ILE B 296
ILE B 306
PHE B 233
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 223
LEU A 228
ILE A 307
ILE A 236
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR A 325
TYR A 179
GLN A 160
THR A 167
ASP A 273
1.62A21.44
None
None
None
None
EDO  A 408 (-3.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 116
ILE B 116
ILE B 108
ILE B  80
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 296
LEU A 251
ILE A 236
ILE A 307
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR B 325
TYR B 179
GLN B 160
THR B 167
ASP B 273
1.60A21.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE B 116
ILE A 116
THR A 121
ILE A  80
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ILE A  72
THR A 322
ILE A 328
LEU A 298
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
ASP A 297
GLN A 197
GLY A 254
VAL A 237
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 307
ILE A 323
ILE A 296
PHE A 342
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLN C 118
GLY C  97
GLY C  78
VAL C  77
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.55A
None
APR  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  96
1.54A
None
APR  C 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  77
1.38A
None
APR  D 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.56A
None
APR  B 201 (-4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  96
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLN D 118
GLY D  97
GLY D  78
VAL D  96
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLN C 118
GLY C  97
GLY C  78
VAL C  96
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.39A
None
APR  B 201 (-4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLN B 118
GLY B  97
GLY B  78
VAL B  96
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  96
1.54A
None
APR  D 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 7
GLN A 118
GLY A  97
SER A 111
GLY A  78
VAL A  77
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  77
1.38A
None
APR  C 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.37A
None
APR  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
THR A6949
ILE A6951
LEU A6981
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE A6969
LEU A7004
ILE A7005
ILE A6926
SER A6927
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ILE A6866
ILE A6955
ILE A6967
SER A6927
PHE A6868
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6955
ILE A6926
ILE A7005
PHE A6985
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6925
THR A6918
ILE A7088
LEU A6892
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6969
ILE A7005
ILE A6926
SER A6927
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6967
THR A6970
ILE A6969
SER A6973
1.33A
None
GTA  A7102 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ILE A6866
ILE A6967
PHE A6954
LEU A6848
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6959
ILE A6955
ILE A6951
ILE A6967
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 106
LEU D 103
ALA D 102
SER C  54
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
LEU C  71
ALA D 110
ILE D 107
ILE D 106
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wqd NSP8
(SARS-CoV-2)		5 / 7
ILE D 166
ILE D 172
THR D 187
ILE D 156
LEU D 184
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wqd NSP8
(SARS-CoV-2)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wqd NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
ILE B 185
ILE B 132
LEU B 117
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A  71
SER A 121
GLY A 120
VAL A  18
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
ILE A 285
THR A 281
PHE A 258
LEU A 290
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A  71
SER A 121
GLY A 120
VAL A  18
1.72A17.66
DMS  A 406 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A 253
ALA A 210
ILE A 213
PHE A 291
1.65A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ILE A 281
LEU A 282
ILE A 213
PHE A 219
1.53A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.70A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.11A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ILE A 281
THR A 257
ILE A 259
LEU A 205
1.54A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ILE A 281
ALA A 211
ILE A 213
ILE A 259
1.54A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLN A 306
GLY A  15
GLY A  11
VAL A  13
1.33A17.66
None
DMS  A 406 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A  29
SER A 121
GLY A 120
VAL A  18
1.73A17.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ILE A 249
THR A 201
ILE A 200
PHE A 294
1.65A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
ILE B 156
ILE B 185
ILE B 132
LEU B 117
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 7
ILE D 166
ILE D 172
THR D 187
ILE D 156
LEU D 184
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
ILE D 156
ILE D 185
ILE D 132
LEU D 117
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  60
ALA B 110
ILE A  68
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE D 106
LEU D 103
ALA D 102
SER C  54
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 506
GLY E 446
SER E 443
VAL E 445
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
ASP E 364
GLY C  63
SER E 366
VAL C  64
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 506
GLY E 447
SER E 443
VAL E 445
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 498
GLY E 504
GLY E 502
VAL E 503
1.61A
None
DMS  E 902 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
ASP A 364
GLY L  63
SER A 366
VAL L  64
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 498
GLY E 504
GLY E 502
VAL E 503
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 506
GLY E 447
SER E 443
VAL E 445
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 506
GLY E 446
SER E 443
VAL E 445
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN A 506
GLY A 446
SER A 443
VAL A 445
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN E 498
GLY E 504
GLY E 502
VAL E 503
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN A 498
GLY A 504
GLY A 502
VAL A 503
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLN A 506
GLY A 447
SER A 443
VAL A 445
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.13A
PEG  A 405 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  96
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  96
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  77
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN C 107
GLY C  79
SER C 111
VAL C  96
1.52A
None
EPE  C 202 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN B 118
GLY B  97
GLY B  78
VAL B  96
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.38A
None
EDO  A 202 (-4.3A)
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN A  62
GLY A  48
GLY A  51
VAL A  49
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY E  78
SER E 128
GLY E  97
VAL E  77
1.38A
None
EPE  E 202 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY E  78
SER E 128
GLY E  97
VAL E  96
1.52A
None
EPE  E 202 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.51A
None
EDO  A 202 (-4.3A)
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  77
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.54A
None
APR  B 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  96
1.54A
None
APR  C 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  77
1.41A
None
APR  D 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  77
1.42A
None
APR  C 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.55A
None
APR  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.41A
None
APR  B 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 7
GLN B 118
GLY B  97
SER B 111
GLY B  78
VAL B  96
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY E  78
SER E 128
GLY E  97
VAL E  96
1.56A
None
APR  E 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY E  78
SER E 128
GLY E  97
VAL E  77
1.41A
None
APR  E 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN C 107
GLY C  79
SER C 111
VAL C  96
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN A 107
GLY A  97
GLY A  78
VAL A  95
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY D  78
SER D 128
GLY D  97
VAL D  96
1.54A
None
APR  D 201 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.40A
None
APR  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  96
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  96
1.52A
None
MES  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN B  62
GLY B  48
GLY B  51
VAL B  49
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY B  78
SER B 128
GLY B  97
VAL B  77
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  96
1.46A
None
MES  C 201 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLN C  62
GLY C  48
GLY C  51
VAL C  49
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY A  78
SER A 128
GLY A  97
VAL A  77
1.38A
None
MES  A 201 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
GLY C  78
SER C 128
GLY C  97
VAL C  77
1.34A
None
MES  C 201 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
GLY A  71
SER A 121
GLY A 120
VAL A  18
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP12
(SARS-CoV-2)		4 / 7
ILE A 244
THR A 141
ILE A 145
LEU A 131
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLN A 210
GLY A 203
PHE A 222
VAL A 233
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP7
NSP8
(SARS-CoV-2)		4 / 7
ILE D 107
THR C   9
PHE D  92
LEU C  55
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 145
LEU A 142
ALA A 130
ILE A 244
0.93A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP8
(SARS-CoV-2)		4 / 7
ILE D 156
ILE D 185
ILE D 132
LEU D 117
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7btf NSP12
(SARS-CoV-2)		5 / 8
ILE A 864
ALA A 863
ILE A 888
ILE A 856
PHE A 920
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP8
(SARS-CoV-2)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
ILE A 333
ILE B 107
SER A 343
LEU B 103
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLY A 559
SER A 682
GLY A 683
VAL A 560
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7btf NSP8
(SARS-CoV-2)		4 / 7
ILE D 166
THR D 187
ILE D 156
LEU D 184
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7btf NSP12
(SARS-CoV-2)		4 / 8
LEU A 862
ALA A 863
ILE A 888
ILE A 856
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
ILE A 200
ILE A 106
THR A 135
ILE A 136
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.77A
None
DMS  A 404 (-4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 7
ILE D 106
ILE D 120
PHE D 147
LEU C  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLN A 210
GLY A 203
PHE A 222
VAL A 233
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 145
LEU A 142
ALA A 130
ILE A 244
0.93A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 862
ALA A 863
ILE A 888
ILE A 856
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 888
LEU A 885
ALA A 863
ILE A 864
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 7
ILE A 333
ILE B 107
SER A 343
LEU B 103
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 536
ALA A 376
ILE A 539
SER A 343
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLY A 559
SER A 682
GLY A 683
VAL A 560
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv1 NSP8
(SARS-CoV-2)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 837
ALA A 840
ILE A 548
SER A 861
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ILE A 244
THR A 141
ILE A 145
LEU A 131
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv2 NSP8
(SARS-CoV-2)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 145
LEU A 142
ALA A 130
ILE A 244
0.93A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLN A 661
GLY A 559
SER A 681
GLY A 683
1.52A
None
U  T  10 ( 3.5A)
None
U  T  10 ( 3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 864
ALA A 863
ILE A 888
ILE A 856
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 888
LEU A 885
ALA A 863
ILE A 864
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ILE A 466
ILE A 307
PHE A 313
LEU A 636
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
ILE B 132
THR A 393
ILE A 450
LEU A 388
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLY A 559
SER A 682
GLY A 683
VAL A 560
1.59A
 U  T  10 ( 3.5A)
U  T  10 (-2.9A)
U  T  10 ( 3.1A)
U  T  10 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		7bv2 NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
ILE B 185
THR B 141
ILE B 132
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ASP A 377
SER A 343
GLY A 345
VAL A 354
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
LEU A 862
ALA A 863
ILE A 888
ILE A 856
1.17A
 U  P  17 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLN A 210
GLY A 203
PHE A 222
VAL A 233
1.51A
None