Ligand ID: RAU


Drugbank ID:
DB01367
(Rasagiline)


Indication:
For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.

Get human targets for RAU in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'RAU' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.79A
None
NHE  A 202 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
None
None
None
NHE  A 202 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
None
None
None
NHE  A 202 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
None
None
None
NHE  A 202 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.77A
None
None
None
None
NHE  A 202 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.74A
None
NHE  A 202 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.77A
None
NHE  A 202 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6vxs NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
MET A 210
GLY A 239
VAL A 304
TYR A 238
PHE A 222
1.67A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
MET A 210
GLY A 239
VAL A 304
TYR A 238
PHE A 222
1.65A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.67A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.66A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6w02 NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.71A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6w02 NSP3
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.71A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6w02 NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.71A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6w02 NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.75A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.71A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.75A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.73A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.74A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.74A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.73A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.71A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.71A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.73A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.77A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.76A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.71A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.73A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
MET C 169
SER C 262
VAL C 165
MET C 243
PHE C 304
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
VAL C 165
MET C 243
PHE C 304
MET C 169
SER C 262
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
VAL C 165
MET C 243
PHE C 304
MET C 169
SER C 262
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
MET C 169
SER C 262
VAL C 165
MET C 243
PHE C 304
1.73A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
VAL C 165
MET C 243
PHE C 304
MET C 169
SER C 262
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
VAL C 165
MET C 243
PHE C 304
MET C 169
SER C 262
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6wcf NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wen NSP3
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 12
SER A 284
GLY A 277
VAL A 299
LEU A 247
TYR A 272
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 10
SER A 284
GLY A 277
VAL A 299
LEU A 247
TYR A 272
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 11
VAL A 299
LEU A 247
TYR A 272
SER A 284
GLY A 277
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 11
VAL A 299
LEU A 247
TYR A 272
SER A 284
GLY A 277
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 10
VAL A 299
LEU A 247
TYR A 272
SER A 284
GLY A 277
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 11
VAL A 299
LEU A 247
TYR A 272
SER A 284
GLY A 277
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6wey NSP3
(SARS-CoV-2)		5 / 10
SER A 284
GLY A 277
VAL A 299
LEU A 247
TYR A 272
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
LEU B 291
PHE B 274
TRP B 301
SER A 318
GLY B 287
1.71A
None
None
CL  B 401 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
LEU B 291
PHE B 274
TRP B 301
SER A 318
GLY B 287
1.71A
None
None
CL  B 401 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
MET A 210
GLY A 239
VAL A 304
TYR A 238
PHE A 222
1.66A21.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
MET B 210
GLY B 239
VAL B 304
TYR B 238
PHE B 222
1.68A21.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL B 304
TYR B 238
PHE B 222
MET B 210
GLY B 239
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL B 304
TYR B 238
PHE B 222
MET B 210
GLY B 239
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL B 304
TYR B 238
PHE B 222
MET B 210
GLY B 239
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL B 304
TYR B 238
PHE B 222
MET B 210
GLY B 239
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
MET B 210
GLY B 239
VAL B 304
TYR B 238
PHE B 222
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
MET A 210
GLY A 239
VAL A 304
TYR A 238
PHE A 222
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A 304
TYR A 238
PHE A 222
MET A 210
GLY A 239
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
VAL A 165
MET A 243
PHE A 304
MET A 169
SER A 262
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
VAL A 165
MET A 243
PHE A 304
MET A 169
SER A 262
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 10
VAL A 165
MET A 243
PHE A 304
MET A 169
SER A 262
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 10
MET A 169
SER A 262
VAL A 165
MET A 243
PHE A 304
1.75A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
VAL A 165
MET A 243
PHE A 304
MET A 169
SER A 262
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
MET A 169
SER A 262
VAL A 165
MET A 243
PHE A 304
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.74A
EDO  D 203 (-3.6A)
None
None
None
EDO  D 202 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.76A
EDO  D 203 (-3.6A)
None
None
None
EDO  D 202 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.74A
None
None
EDO  D 202 (-4.3A)
EDO  D 203 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL D  95
LEU D  43
TYR D  68
SER D  80
GLY D  73
1.74A
None
None
EDO  D 202 (-4.3A)
EDO  D 203 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL E  95
LEU E  43
TYR E  68
SER E  80
GLY E  73
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER D  80
GLY D  73
VAL D  95
LEU D  43
TYR D  68
1.79A
EDO  D 203 (-3.6A)
None
None
None
EDO  D 202 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER E  80
GLY E  73
VAL E  95
LEU E  43
TYR E  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.74A
None
None
None
EDO  A 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.74A
EDO  A 204 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
None
None
EDO  A 204 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
None
None
EDO  A 204 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.73A
EDO  A 204 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.76A
EDO  A 204 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.76A
None
None
None
EDO  A 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.74A
None
None
None
EDO  A 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.75A
EDO  A 204 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER C  80
GLY C  73
VAL C  95
LEU C  43
TYR C  68
1.78A
EDO  A 204 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
SER A  80
GLY A  73
VAL A  95
LEU A  43
TYR A  68
1.77A
EDO  A 204 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B  80
GLY B  73
VAL B  95
LEU B  43
TYR B  68
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.75A
None
None
None
EDO  A 204 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL A  95
LEU A  43
TYR A  68
SER A  80
GLY A  73
1.73A
None
None
None
EDO  A 204 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
VAL C  95
LEU C  43
TYR C  68
SER C  80
GLY C  73
1.74A
None
None
None
EDO  A 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  95
LEU B  43
TYR B  68
SER B  80
GLY B  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 10
SER C  61
GLN C  63
GLY C  64
VAL C  58
LEU C  20
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 11
VAL C  58
LEU C  20
SER C  61
GLN C  63
GLY C  64
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 11
VAL C  58
LEU C  20
SER C  61
GLN C  63
GLY C  64
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 12
SER C  61
GLN C  63
GLY C  64
VAL C  58
LEU C  20
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 10
SER C  61
GLN C  63
GLY C  64
VAL C  58
LEU C  20
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		7bv2 NSP7
(SARS-CoV-2)		5 / 11
VAL C  58
LEU C  20
SER C  61
GLN C  63
GLY C  64
1.68A
None