Ligand ID: QEL


Drugbank ID:
DB08954
(Ifenprodil)


Indication:

Get human targets for QEL in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'QEL' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		5r7y 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.61A20.05
20.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		5r83 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.61A20.05
20.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.63A17.44
17.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.62A17.44
17.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
TYR C 239
THR C 198
LEU C 286
PRO C 132
ILE C 200
1.72A20.05

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.76A20.05

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
TYR D 239
THR D 198
LEU D 286
PRO D 132
ILE D 200
1.74A20.05

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
TYR C 239
THR C 198
LEU C 286
PRO C 132
ILE C 200
1.68A20.05
20.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
TYR A 530
THR A 531
LEU A 372
ALA A 526
THR B  84
1.77A17.21
17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.71A20.83
21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.67A15.27
13.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 5
TYR C 380
THR C 430
PHE C 429
ARG A 983
LEU A 984
1.79A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.67A15.27
13.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.66A14.53
13.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
TYR B 194
THR B 322
ILE B 328
THR B 167
GLU B  69
1.64A21.63
19.55
None
GOL  B 406 (-3.3A)
None
GOL  B 402 (-3.4A)
GOL  B 402 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
PRO B  74
ALA B  70
ILE B  69
THR A 149
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
TYR A 873
THR A 874
PRO A1053
GLN A 784
PHE A 782
1.77A14.75
13.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.76A14.98
13.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
THR A1077
PRO B 897
ALA B 903
GLN B 913
GLU B 918
1.53A14.75
13.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
THR A1077
PRO B 897
ALA B 903
GLN B 913
GLU B 918
1.51A14.75
13.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
TYR A 917
ALA C1078
ILE C1081
PHE C1089
PRO A 897
1.75A14.98
13.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR B 279
ILE B 270
PHE B 269
THR B 167
GLU B  69
1.43A21.77
19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 264
THR A 265
PRO A 299
ALA A 249
ILE A 300
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR C 264
THR C 265
PRO C 299
ALA C 249
ILE C 300
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR B 264
THR B 265
PRO B 299
ALA B 249
ILE B 300
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
THR C 102
LEU C 290
GLN C 122
THR C 281
GLU C 280
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
THR A 102
LEU A 290
GLN A 122
THR A 281
GLU A 280
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 5
TYR B  56
THR B   9
PHE B   8
LEU B  36
1.52A18.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
TYR A 264
THR A 265
PRO A 299
ALA A 249
ILE A 300
1.76A18.38
19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 5
TYR A  56
THR A   9
PHE A   8
LEU A  36
1.44A18.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
TYR C 264
THR C 265
PRO C 299
ALA C 249
ILE C 300
1.63A18.38
19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
TYR B 264
THR B 265
PRO B 299
ALA B 249
ILE B 300
1.77A18.38
19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 5
TYR C  56
THR C   9
PHE C   8
LEU C  36
1.38A18.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
TYR D 268
THR D 265
ARG D 277
ALA C 313
THR D 282
1.78A15.22
17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR E 268
THR E 265
GLN E 272
PHE E 274
PRO A 258
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
TYR B 268
THR B 265
ARG B 277
ALA A 313
THR B 282
1.75A15.22
17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR D 268
THR D 265
ARG D 277
ALA C 313
THR D 282
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR B 268
THR B 265
ARG B 277
ALA A 313
THR B 282
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
TYR E 268
THR E 265
GLN E 272
PHE E 274
PRO A 258
1.76A14.91
17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR E 268
THR E 265
ARG E 277
ALA F 313
THR E 282
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
TYR E 268
THR E 265
ARG E 277
ALA F 313
THR E 282
1.77A15.22
17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
TYR E 268
THR E 265
GLN E 272
PHE E 274
PRO A 258
1.79A10.15
8.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
THR A 113
ARG A 139
PRO A 112
ILE A 100
PRO B 119
1.77A21.95
21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR A 194
THR A 322
ILE A 328
THR A 167
GLU A  69
1.73A
None
None
None
None
EDO  A 408 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
TYR B 194
THR B 322
ILE B 328
THR B 167
GLU B  69
1.69A21.81
21.62
None
EDO  B 406 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		6 / 12
THR A 113
ARG A 139
PRO A 112
ILE A 100
THR B 115
PRO B 119
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
THR A 113
ARG A 139
ILE A 100
THR B 115
PRO B 119
1.68A21.81
21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR B 194
THR B 322
ILE B 328
THR B 167
GLU B  69
1.70A
None
EDO  B 406 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
THR B 113
PRO B 112
ILE B 100
THR A 115
PRO A 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
TYR A 194
THR A 322
ILE A 328
THR A 167
GLU A  69
1.72A21.81
21.62
None
None
None
None
EDO  A 408 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 5
TYR A  56
THR A   9
PHE A   8
LEU A  36
1.45A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.65A17.44
18.13
None
DMS  A 404 (-3.8A)
None
DMS  A 404 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
TYR B 149
THR B 148
ALA B 188
ILE B 156
PRO B 121
1.78A14.76
15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.64A
PEG  A 404 (-3.8A)
None
PEG  A 404 ( 3.6A)
None
PEG  A 405 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
TYR A 239
THR A 198
LEU A 286
PRO A 132
ILE A 200
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7btf NSP12
(SARS-CoV-2)		5 / 10
TYR A 831
LEU A 829
ALA A 866
ILE A 837
GLU A 922
1.33A20.65
22.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		7btf NSP8
(SARS-CoV-2)		5 / 11
TYR D 149
THR D 148
ALA D 188
ILE D 156
PRO D 121
1.69A20.11
19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 831
LEU A 829
ALA A 866
ILE A 837
GLU A 922
1.31A17.68
17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 831
LEU A 829
ALA A 866
ILE A 837
GLU A 922
1.33A17.21
17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7btf NSP8
(SARS-CoV-2)		5 / 10
TYR D 149
THR D 148
ALA D 188
ILE D 156
PRO D 121
1.79A14.54
13.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7btf NSP8
(SARS-CoV-2)		5 / 11
TYR D 149
THR D 148
ALA D 188
ILE D 156
PRO D 121
1.74A20.11
18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7btf NSP8
(SARS-CoV-2)		5 / 12
TYR D 149
THR D 148
ALA D 188
ILE D 156
PRO D 121
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
TYR A 653
THR A 531
LEU A 655
ALA A 660
ILE A 536
1.68A20.87
22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
TYR A 653
THR A 531
LEU A 655
ALA A 660
ILE A 536
1.72A20.87
22.27
None