Ligand ID: PNX


Drugbank ID:
DB00806
(Pentoxifylline)


Indication:
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.

Get human targets for PNX in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'PNX' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 195
THR A 196
PHE A 185
GLU A 240
1.63A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  86
PHE A 112
GLY A 149
GLU A 178
1.79A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  86
GLY A 174
THR A 175
PHE A 140
1.62A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 195
PHE A 185
GLY A 183
GLU A 240
1.75A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A 212
GLY A 258
THR A 257
GLY A 251
1.30A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		4 / 7
GLY E 404
ASP E 442
TYR E 508
ARG E 509
1.62A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A19.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY B 170
THR B 169
GLU B 166
GLY D   2
1.38A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
VAL B  86
THR B 175
PHE B 112
GLY B 149
GLU B 178
1.70A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY D 195
THR D 196
PHE D 185
GLU D 240
1.42A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
GLY D   2
PHE B 140
SER D   1
ARG D   4
1.50A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR B 161
GLY D   2
SER D   1
ARG D   4
1.79A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
VAL D  86
THR D 175
PHE D 112
GLY D 149
GLU D 178
1.72A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C 170
THR C 169
GLU C 166
GLY A   2
1.34A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
VAL A  86
THR A 175
PHE A 112
GLY A 149
GLU A 178
1.75A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
GLY D   2
PHE B 140
SER D   1
ARG D   4
1.49A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C 195
THR C 196
PHE C 185
GLU C 240
1.40A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
VAL B  86
GLY B 174
THR B 175
PHE B 185
GLY B 183
1.80A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A 170
THR A 169
GLU A 166
GLY C   2
1.32A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL B 204
THR B 199
GLY B 109
GLU B 288
1.42A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
VAL C  86
THR C 175
PHE C 112
GLY C 149
GLU C 178
1.74A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY D 170
THR D 169
GLU D 166
GLY B   2
1.32A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.39A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY C 115
THR C 116
GLY C 121
ALA C 120
1.03A13.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASN A 489
ILE A 488
GLN A 570
PHE A 528
1.54A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.78A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 320
GLU A 180
GLY A 179
ALA A 250
1.42A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 359
GLY A 345
THR A 344
PHE A 348
1.34A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6m71 NSP8
(SARS-CoV-2)		4 / 7
TRP B 154
SER B 151
THR B 123
LEU B 122
1.66A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 424
PHE A 440
GLY A 839
GLU A 431
1.38A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6m71 NSP12
(SARS-CoV-2)		4 / 8
THR A 769
GLY A 774
ALA A 771
GLU A 610
1.42A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
GLY B 885
PHE B 888
SER B 884
ARG B 905
1.61A15.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE C 888
GLY C 880
ALA C 879
GLU C 819
0.81A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASN B 801
PHE B 898
MET B 902
PHE B 927
1.07A14.25
NAG  B1309 (-1.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6vxs NSP3
(SARS-CoV-2)		4 / 8
VAL B  30
GLY B  85
ALA B  89
GLU B  25
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
TYR A 265
GLY A 107
PHE A 106
SER A 116
1.61A16.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASN B 801
PHE B 898
MET B 902
PHE B 927
0.97A13.76
NAG  B1314 (-1.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE C 888
GLY C 880
ALA C 879
GLU C 819
0.82A20.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 888
GLY A 880
ALA A 879
GLU A 819
0.83A20.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASN C 801
PHE C 898
MET C 902
PHE C 927
0.97A13.76
NAG  C1313 (-1.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL B1033
SER B1051
THR B 881
LEU B 878
1.79A20.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
TRP B  52
TYR B 112
SER A 105
ARG A 107
1.69A16.01
MES  A 203 (-3.7A)
None
None
MES  A 203 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
GLY C 114
THR C 115
GLY C 120
ALA C 119
1.07A12.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY B 165
ASP B  88
TYR B  89
ARG B  91
1.47A22.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY B 165
ASP B  88
TYR B  89
ARG B  91
1.54A22.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
VAL C 433
THR C 376
PHE H  29
GLU H  56
1.74A13.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  53
THR C 376
PHE H  29
GLU H  56
1.58A14.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
GLY C 404
ASP C 442
TYR C 508
ARG C 509
1.72A13.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
TYR C 505
GLY C 404
ASP C 405
GLU C 406
TYR C 449
1.75A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
VAL C 511
GLY C 339
GLU C 340
ALA C 344
1.73A13.04
None
NAG  C 601 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
GLY C 404
ASP C 442
TYR C 508
ARG C 509
1.74A13.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6963
GLY A7076
ALA A6858
1.70A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4322
GLY B4347
ALA B4324
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6962
PHE A6985
ALA A6960
1.72A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6869
ALA A6870
1.31A
SAM  A7104 (-3.6A)
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
TYR B4349
GLY A6875
PHE A6901
SER A6872
1.71A
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6963
GLY A7076
ALA A6858
1.74A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6876
GLY A6879
GLY A6869
ALA A6870
1.33A
None
SAM  A7104 (-3.6A)
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6871
ALA A6870
1.45A13.53
SAM  A7104 (-3.6A)
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6871
ALA A6877
1.70A13.53
SAM  A7104 (-3.6A)
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6902
GLY A6871
GLY A6869
ALA A6870
1.64A13.53
None
SAM  A7104 (-4.4A)
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4323
GLY B4347
ALA B4324
1.74A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6962
GLY A7076
ALA A6858
1.55A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6879
GLY A6871
ALA A6870
1.33A
None
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6869
GLY A6871
ALA A6870
GLU A7001
1.54A13.53
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL B4295
GLY A6879
GLY A6871
ALA A6877
1.45A12.50
None
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A 121
THR A  33
GLY A  85
ALA A  89
1.51A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B  97
GLY B  78
ALA B 112
1.74A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B 121
THR B  33
GLY B  85
ALA B  89
1.43A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A  96
GLY A  47
ALA A  50
GLU A 104
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B 142
PHE B 132
GLY B 133
ALA B 134
1.73A14.50
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A  96
GLY A  48
ALA A  50
GLU A 104
1.55A14.50
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B  36
GLY B  97
GLY B  78
ALA B 112
1.67A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B 155
GLY B 130
PHE B 132
ALA B 129
1.80A14.50
None
MES  B 201 ( 3.4A)
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  78
ALA A 112
1.77A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B  97
GLY B  79
ALA B 112
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A  24
GLY A  48
GLY A  46
ALA A  50
1.74A14.50
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A  36
GLY A  97
GLY A  78
ALA A 112
1.64A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A  96
GLY A  46
ALA A  50
GLU A 104
1.55A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w6y NSP3
(SARS-CoV-2)		4 / 8
VAL A 147
PHE A 132
GLY A  97
ALA A 112
1.48A14.50
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6963
GLY A7076
ALA A6858
1.71A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6963
GLY A7076
ALA A6858
1.68A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4322
GLY B4347
ALA B4324
1.36A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C7057
GLY C6962
GLY C7076
ALA C6858
1.53A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4323
GLY B4347
ALA B4324
1.74A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A6876
GLY A6879
GLY A6869
ALA A6870
1.34A14.16
None
SAM  A7102 ( 3.4A)
SAM  A7102 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C6865
GLY C6963
GLY C7076
ALA C6858
1.75A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL D4295
GLY C6879
GLY C6871
ALA C6877
1.46A12.74
None
SAM  C7105 ( 3.4A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C6876
GLY C6879
GLY C6869
ALA C6870
1.35A14.16
None
SAM  C7105 ( 3.4A)
SAM  C7105 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C7057
GLY C6962
PHE C6985
ALA C6960
1.71A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6869
ALA A6870
1.27A14.16
SAM  A7102 ( 3.4A)
None
SAM  A7102 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6962
PHE A6985
ALA A6960
1.71A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL B4295
GLY A6879
GLY A6871
ALA A6877
1.47A12.74
None
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6871
ALA A6870
1.48A14.16
SAM  A7102 ( 3.4A)
None
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6879
GLY A6871
ALA A6870
1.31A14.16
None
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL C6876
GLY D4322
GLY D4347
ALA D4324
1.34A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL A7057
GLY A6962
GLY A7076
ALA A6858
1.54A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C6865
GLY C6879
GLY C6871
ALA C6870
1.32A14.16
None
SAM  C7105 ( 3.4A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
THR C6880
GLY C6871
ALA C6877
1.75A14.16
SAM  C7105 ( 3.4A)
None
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
THR C6880
GLY C6871
ALA C6870
1.48A14.16
SAM  C7105 ( 3.4A)
None
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
THR C6880
GLY C6869
ALA C6870
1.29A14.16
SAM  C7105 ( 3.4A)
None
SAM  C7105 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6871
ALA A6877
1.75A14.16
SAM  A7102 ( 3.4A)
None
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL C6876
GLY D4323
GLY D4347
ALA D4324
1.73A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C7057
GLY C6963
GLY C7076
ALA C6858
1.67A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE C 123
PHE C 304
MET C 243
PHE C 173
1.73A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ILE A 123
PHE A 304
MET A 243
PHE A 173
1.75A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wcf NSP3
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wen NSP3
(SARS-CoV-2)		4 / 8
VAL A 121
THR A  33
GLY A  85
ALA A  89
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wen NSP3
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wen NSP3
(SARS-CoV-2)		4 / 8
VAL A  96
GLY A  47
ALA A  50
GLU A 104
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wey NSP3
(SARS-CoV-2)		4 / 8
VAL A 300
GLY A 251
ALA A 254
GLU A 308
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR D 333
GLY D 275
PHE D 274
ARG D 277
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR F 333
PHE E 315
SER E 312
ARG F 277
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY D 335
THR D 334
GLY C 284
GLU C 323
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR A 333
PHE B 315
SER B 312
ARG A 277
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR E 333
GLY E 275
PHE E 274
ARG E 277
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR B 333
GLY B 275
PHE B 274
ARG B 277
1.44A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 333
GLY C 275
PHE C 274
ARG C 277
1.43A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR F 333
GLY F 275
PHE F 274
ARG F 277
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR B 333
PHE A 315
SER A 312
ARG B 277
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR A 333
GLY A 275
PHE A 274
ARG A 277
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR E 333
GLY E 275
PHE E 274
ARG E 277
1.46A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR D 333
GLY D 275
PHE D 274
ARG D 277
1.46A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 333
PHE D 315
SER D 312
ARG C 277
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 333
GLY C 275
PHE C 274
ARG C 277
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR B 333
GLY B 275
PHE B 274
ARG B 277
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR A 333
GLY A 275
PHE A 274
ARG A 277
1.44A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR F 333
GLY F 275
PHE F 274
ARG F 277
1.43A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL C6876
GLY C6879
GLY C6869
ALA C6870
1.31A
None
SAH  C7102 (-3.5A)
SAH  C7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4322
GLY B4347
ALA B4324
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL C6865
GLY C6879
GLY C6871
ALA C6870
1.33A
None
SAH  C7102 (-3.5A)
SAH  C7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL C6876
GLY D4322
GLY D4347
ALA D4324
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6879
THR C6880
GLY C6869
ALA C6870
1.29A
SAH  C7102 (-3.5A)
None
SAH  C7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6876
GLY A6879
GLY A6869
ALA A6870
1.32A
None
SAH  A7102 (-3.5A)
SAH  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6879
GLY A6871
ALA A6870
1.31A
None
SAH  A7102 (-3.5A)
SAH  A7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6869
ALA A6870
1.29A
SAH  A7102 (-3.5A)
None
SAH  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY B 137
GLU B 136
GLY B  69
ALA B 134
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY C 114
THR C 115
GLY C 120
ALA C 119
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY A 137
GLU A 136
GLY A  69
ALA A 134
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY B 114
THR B 115
GLY B 120
ALA B 119
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY D 114
THR D 115
GLY D 120
ALA D 119
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY A 114
THR A 115
GLY A 120
ALA A 119
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6879
GLY A6871
ALA A6870
1.32A
None
SFG  A7103 ( 3.5A)
SFG  A7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL C6865
GLY C6879
GLY C6871
ALA C6870
1.32A
None
SFG  C7103 ( 3.5A)
SFG  C7103 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6869
ALA A6870
1.27A
SFG  A7103 ( 3.5A)
None
SFG  A7103 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4322
GLY B4347
ALA B4324
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
VAL C6876
GLY D4322
GLY D4347
ALA D4324
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL C6876
GLY C6879
GLY C6869
ALA C6870
1.34A
None
SFG  C7103 ( 3.5A)
SFG  C7103 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
THR C6880
GLY C6869
ALA C6870
1.29A
SFG  C7103 ( 3.5A)
None
SFG  C7103 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL A6876
GLY A6879
GLY A6869
ALA A6870
1.32A
None
SFG  A7103 ( 3.5A)
SFG  A7103 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY B 165
ASP B  88
TYR B  89
ARG B  91
1.59A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
TYR A 231
ILE A 307
PHE A 303
GLN A 310
1.77A20.22
SO4  A 410 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY A 165
ASP A  88
TYR A  89
ARG A  91
1.52A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY A 165
ASP A  88
TYR A  89
ARG A  91
1.60A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
TYR B 231
ILE B 307
PHE B 303
GLN B 310
1.78A20.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
GLY B 165
ASP B  88
TYR B  89
ARG B  91
1.51A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL C  30
GLY C  85
ALA C  89
GLU C  25
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL D 142
GLY D  97
GLY D  79
ALA D 112
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A  42
GLY B  97
PHE B 132
SER B 128
1.66A18.58
None
None
APR  B 201 (-3.6A)
APR  B 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6876
GLY A6879
GLY A6869
ALA A6870
1.35A
None
SAH  A7101 (-3.5A)
SAH  A7101 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
VAL A6876
GLY B4322
GLY B4347
ALA B4324
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A6865
GLY A6879
GLY A6871
ALA A6870
1.31A
None
SAH  A7101 (-3.5A)
SAH  A7101 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
THR A6880
GLY A6869
ALA A6870
1.29A
SAH  A7101 (-3.5A)
None
SAH  A7101 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ASN A 110
SER A 111
ALA A 114
ASP A 286
1.60A19.79
None
PO4  A 502 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 212
GLY A 258
THR A 257
GLY A 251
1.28A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 195
PHE A 185
GLY A 183
GLU A 240
1.77A15.89
DMS  A 404 ( 4.4A)
None
None
DMS  A 404 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  86
GLY A 174
THR A 175
PHE A 140
1.62A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 195
THR A 196
PHE A 185
GLU A 240
1.62A15.89
DMS  A 404 ( 4.4A)
DMS  A 404 (-4.8A)
None
DMS  A 404 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  86
THR A 175
PHE A 112
GLY A 149
1.67A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  86
PHE A 112
GLY A 149
GLU A 178
1.79A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
TRP B 154
VAL A  53
SER A  57
LEU B 122
1.44A13.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
GLY A  74
THR A  75
GLY A  80
ALA A  79
0.85A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY E 404
ASP E 442
TYR E 508
ARG E 509
1.73A17.98
DMS  E 902 (-3.4A)
None
DMS  E 902 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 404
ASP A 442
TYR A 508
ARG A 509
1.78A17.98
DMS  A 903 (-3.5A)
None
DMS  A 903 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY E 504
ASP E 442
TYR E 508
ARG E 509
1.54A17.98
DMS  E 902 ( 4.6A)
None
DMS  E 902 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
TRP L  56
VAL E 382
SER E 383
LEU E 390
1.76A16.55
DMS  L1601 (-3.8A)
DMS  L1601 (-4.2A)
DMS  L1601 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY E 404
ASP E 442
TYR E 508
ARG E 509
1.76A17.98
DMS  E 902 (-3.4A)
None
DMS  E 902 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASN A 394
ILE A 358
PHE A 338
PHE A 515
1.61A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 404
ASP A 442
TYR A 508
ARG A 509
1.75A17.98
DMS  A 903 (-3.5A)
None
DMS  A 903 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 212
GLY A 258
THR A 257
GLY A 251
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 504
ASP A 442
TYR A 508
ARG A 509
1.55A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY E 404
ASP E 442
TYR E 508
ARG E 509
1.73A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 404
ASP A 442
TYR A 508
ARG A 509
1.73A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 404
ASP A 442
TYR A 508
ARG A 509
1.76A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6yor IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
TRP L  56
VAL E 382
SER E 383
LEU E 390
1.75A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		6yor IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
TRP C  56
VAL A 382
SER A 383
LEU A 390
1.76A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 212
GLY A 258
THR A 257
GLY A 251
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A
None
PEG  A 404 (-3.0A)
PEG  A 405 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL E 142
GLY E  97
GLY E  79
ALA E 112
1.37A
None
None
EPE  E 203 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL D 142
GLY D  97
GLY D  79
ALA D 112
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B  97
GLY B  79
ALA B 112
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.39A
None
EDO  A 202 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C  96
GLY C  47
ALA C  50
GLU C 104
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C 142
GLY C  97
GLY C  79
ALA C 112
1.40A
None
None
EPE  C 202 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B  96
GLY B  47
ALA B  50
GLU B 104
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C 142
GLY C  97
GLY C  79
ALA C 112
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL E 142
GLY E  97
GLY E  79
ALA E 112
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B  97
GLY B  79
ALA B 112
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL D 142
GLY D  97
GLY D  79
ALA D 112
1.37A
None
None
EDO  D 203 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A 142
GLY A  97
GLY A  79
ALA A 112
1.36A
None
None
EDO  A 204 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B 121
THR B  33
GLY B  85
ALA B  89
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B  97
GLY B  79
ALA B 112
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B 142
GLY B 133
ALA B 134
GLU A  25
1.26A
None
None
EDO  B 204 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B   3
THR B  33
GLY B  85
ALA B  89
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C 142
GLY C  97
GLY C  79
ALA C 112
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7btf NSP12
(SARS-CoV-2)		4 / 8
VAL A 359
GLY A 345
THR A 344
PHE A 348
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		7btf NSP8
(SARS-CoV-2)		4 / 7
TRP B 154
SER B 151
THR B 123
LEU B 122
1.70A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7btf NSP12
(SARS-CoV-2)		4 / 8
VAL A 320
GLU A 180
GLY A 179
ALA A 250
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.79A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		7btf NSP12
(SARS-CoV-2)		4 / 6
SER A 255
ALA A 253
HIS A 256
ASP A 260
1.73A20.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		7btf NSP12
(SARS-CoV-2)		4 / 7
ASN A 489
ILE A 488
GLN A 570
PHE A 528
1.53A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
THR A 199
GLY A 109
GLU A 288
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 212
GLY A 258
THR A 257
GLY A 251
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
TRP D 154
ASN D 105
SER D 151
ALA D 102
1.59A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		7bv2 NSP8
(SARS-CoV-2)		4 / 7
TRP B 154
SER B 151
THR B 123
LEU B 122
1.72A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 359
GLY A 345
THR A 344
PHE A 348
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 667
GLY A 559
THR A 540
GLY A 503
1.42A
None
U  T  10 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 320
GLU A 180
GLY A 179
ALA A 250
1.37A
None