Ligand ID: P77


Drugbank ID:
DB00433
(Prochlorperazine)


Indication:
For the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes.

Get human targets for P77 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'P77' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ASP A 248
SER A 254
PHE A 294
LEU A 205
1.64A22.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.62A22.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 10
LEU D1166
ASP D1165
SER E 968
PHE E 970
ILE E 973
1.52A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 9
SER E 968
PHE E 970
ILE E 973
LEU D1166
ASP D1165
1.55A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 8
ASP B1184
SER F 943
LEU F 938
ASP F 936
1.39A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 10
SER E 968
PHE E 970
ILE E 973
LEU D1166
ASP D1165
1.53A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 153
PHE A 150
SER A 113
CYH A 160
1.76A16.16

None
None
DMS  A 402 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.60A16.16

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.64A16.67

DMS  A 403 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER C 123
PHE C 140
SER C 147
LEU C  27
1.58A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER D 123
PHE D 140
SER D 147
LEU D  27
1.48A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.52A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER B 123
PHE B 140
SER B 147
LEU B  27
1.51A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 216
PHE A   3
CYH A 300
LEU A 253
1.65A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.60A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 248
SER A 254
PHE A 294
LEU A 205
1.71A16.67

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  45
PHE A  35
LEU A 127
1.54A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 390
SER A 672
PHE A 407
LEU B 184
1.48A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 784
SER A 709
PHE A 753
LEU A 727
1.69A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  48
LEU A 207
ASP A 208
1.69A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ASP A 221
SER A 236
CYH A 193
PHE A 192
1.64A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ASP A 208
SER A 236
PHE A 192
ASP A 221
1.74A7.65

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
LEU C 552
SER C 555
PHE C 565
PHE C 559
ASP C 568
1.69A5.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
ASP C 568
PHE C 559
LEU C 552
SER C 555
PHE C 565
1.70A5.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
LEU C 552
SER C 555
PHE C 565
PHE C 559
ASP C 568
1.65A5.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASP A 568
PHE B 855
LEU A 552
ASP A 586
1.29A5.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER A  45
LEU C 585
ASP C 586
PHE C 565
PHE A 855
1.65A5.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
LEU A 585
ASP A 586
PHE A 565
PHE B 855
SER B  45
1.66A5.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASP B 979
SER B 982
LEU B 966
ASP A 571
1.41A5.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASP A 979
SER A 982
LEU A 966
ASP C 571
1.45A5.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP B 301
SER B 208
PHE B 233
LEU B 252
1.43A13.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ASP C 428
SER L  27
PHE C 464
SER C 514
1.64A18.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6w4h NSP16
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.59A18.11
None
None
None
None
SAM  A7102 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6w4h NSP16
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.62A18.11
SAM  A7102 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w4h NSP16
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.36A18.11
SAM  A7102 (-3.7A)
ACT  A7104 (-3.8A)
ACT  A7104 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6w4h NSP16
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.67A18.11
None
None
None
None
SAM  A7102 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6w4h NSP16
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.66A18.11
SAM  A7102 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.64A20.81
SAM  A7104 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.61A20.81
SAM  A7104 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6897
PHE A6868
PHE A6947
ASP A6912
1.54A20.81
SAM  A7104 (-2.8A)
None
EDO  A7102 (-3.8A)
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.35A20.81
SAM  A7104 (-3.8A)
EDO  A7102 (-3.8A)
EDO  A7102 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
ASP A6912
PHE A6868
1.60A20.81
None
None
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
PHE A6901
SER A6903
PHE A6868
LEU A6883
1.69A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6947
PHE A6868
ASP A6897
1.53A20.81
SAM  A7104 (-3.6A)
EDO  A7102 (-3.8A)
None
SAM  A7104 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6868
SER A6896
ASP A7091
1.76A20.81
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.58A20.81
None
None
None
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
PHE A6947
SER A6973
PHE A6868
LEU A7004
1.53A20.81
EDO  A7102 (-3.8A)
EDO  A7102 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A6978
1.76A20.81
SAM  A7104 (-3.8A)
EDO  A7102 (-3.8A)
EDO  A7102 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.65A20.81
None
None
None
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.54A
None
None
None
X77  A 401 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
ASP A6912
PHE A6868
1.58A18.75
None
None
None
SAM  A7102 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.61A18.75
SAM  A7102 ( 3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
PHE C6947
SER C6973
PHE C6868
LEU C7004
1.54A18.75
FMT  C7115 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6947
PHE A6868
ASP A6897
1.57A18.75
SAM  A7102 ( 3.5A)
SAM  A7102 ( 4.8A)
None
SAM  A7102 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ASP C7091
SER C6896
ILE C7088
PHE C6868
ASP C6912
1.65A18.75
None
None
None
None
SAM  C7105 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A6896
SER A6907
LEU C7093
ASP C7091
1.55A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.57A18.75
None
None
None
None
SAM  A7102 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6928
PHE C6947
SER C6973
LEU C6978
1.76A18.75
SAM  C7105 ( 3.7A)
FMT  C7115 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A6907
SER A7090
LEU A6898
ASP A6897
1.68A18.75
None
None
SAM  A7102 ( 3.8A)
SAM  A7102 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.61A18.75
SAM  C7105 ( 3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6928
PHE C6947
SER C6973
LEU C7004
1.37A18.75
SAM  C7105 ( 3.7A)
FMT  C7115 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.64A18.75
SAM  C7105 ( 3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6947
PHE C6868
ASP C6897
1.57A18.75
SAM  C7105 ( 3.5A)
FMT  C7115 ( 3.5A)
None
SAM  C7105 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.64A18.75
None
None
None
None
SAM  A7102 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
ASP C6912
PHE C6868
1.59A18.75
None
None
None
SAM  C7105 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6868
SER A6896
ASP A7091
1.74A18.75
SAM  A7102 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.63A18.75
SAM  A7102 ( 3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A6978
1.77A18.75
SAM  A7102 ( 3.7A)
SAM  A7102 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6897
PHE A6868
PHE A6947
ASP A6912
1.59A18.75
SAM  A7102 ( 2.6A)
None
SAM  A7102 ( 4.8A)
SAM  A7102 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6897
PHE C6868
PHE C6947
ASP C6912
1.59A18.75
SAM  C7105 ( 2.7A)
None
FMT  C7115 ( 3.5A)
SAM  C7105 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.35A18.75
SAM  A7102 ( 3.7A)
SAM  A7102 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
PHE C6868
ASP C6912
1.58A18.75
None
None
None
None
SAM  C7105 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6868
SER C6896
ASP C7091
1.74A18.75
SAM  C7105 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w75 NSP16
(SARS-CoV-2)		4 / 8
PHE A6947
SER A6973
PHE A6868
LEU A7004
1.54A18.75
SAM  A7102 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ASP A 302
SER A 245
CYH A 111
LEU A 113
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.63A
SAH  A7102 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6868
SER A6896
ASP A7091
1.74A
SAH  A7102 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
PHE C6947
SER C6973
PHE C6868
LEU C7004
1.53A
SAH  C7102 (-4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.34A
SAH  A7102 (-3.7A)
SAH  A7102 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.61A
SAH  C7102 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
ASP C6912
PHE C6868
1.59A
None
None
None
SAH  C7102 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
PHE C6868
ASP C6912
1.58A
None
None
None
None
SAH  C7102 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6947
PHE C6868
ASP C6897
1.57A
SAH  C7102 (-3.3A)
SAH  C7102 (-4.6A)
None
SAH  C7102 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6868
SER C6896
ASP C7091
1.76A
SAH  C7102 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6897
PHE A6868
PHE A6947
ASP A6912
1.59A
SAH  A7102 (-2.6A)
None
SAH  A7102 (-4.7A)
SAH  A7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6907
SER A7090
LEU A6898
ASP A6897
1.73A
None
None
SAH  A7102 (-3.9A)
SAH  A7102 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP C6928
PHE C6947
SER C6973
LEU C7004
1.35A
SAH  C7102 (-3.7A)
SAH  C7102 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP C6928
PHE C6947
SER C6973
LEU C6978
1.76A
SAH  C7102 (-3.7A)
SAH  C7102 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.64A
None
None
None
None
SAH  A7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
ASP A6912
PHE A6868
1.57A
None
None
None
SAH  A7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.56A
None
None
None
None
SAH  A7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
PHE A6947
SER A6973
PHE A6868
LEU A7004
1.54A
SAH  A7102 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.60A
SAH  A7102 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.65A
SAH  C7102 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP C6897
PHE C6868
PHE C6947
ASP C6912
1.60A
SAH  C7102 (-2.6A)
None
SAH  C7102 (-4.6A)
SAH  C7102 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6947
PHE A6868
ASP A6897
1.57A
SAH  A7102 (-3.5A)
SAH  A7102 (-4.7A)
None
SAH  A7102 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ASP D  82
SER D  79
SER C 105
ASP D 144
1.44A
 ZN  D 202 (-2.7A)
ZN  D 202 ( 4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
ASP C6912
PHE C6868
1.59A
None
None
None
SFG  C7103 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6897
PHE C6868
PHE C6947
ASP C6912
1.59A
SFG  C7103 ( 2.6A)
None
FMT  C7105 ( 3.5A)
SFG  C7103 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.57A
None
None
None
None
SFG  A7103 ( 3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
PHE C6947
SER C6973
PHE C6868
LEU C7004
1.53A
FMT  C7105 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
PHE A6947
SER A6973
PHE A6868
LEU A7004
1.53A
SFG  A7103 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
SER A6896
SER A6907
LEU C7093
ASP C7091
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6947
PHE C6868
ASP C6897
1.57A
SFG  C7103 ( 3.4A)
FMT  C7105 ( 3.5A)
None
SFG  C7103 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.63A
SFG  A7103 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6928
PHE C6947
SER C6973
LEU C7004
1.37A
SFG  C7103 ( 3.7A)
FMT  C7105 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.35A
SFG  A7103 ( 3.6A)
SFG  A7103 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP C7091
SER C6896
ILE C7088
PHE C6868
ASP C6912
1.58A
None
None
None
None
SFG  C7103 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.61A
SFG  C7103 ( 3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
ASP A6912
PHE A6868
1.58A
None
None
None
SFG  A7103 ( 3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.60A
SFG  A7103 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.64A
None
None
None
None
SFG  A7103 ( 3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP A6897
PHE A6868
PHE A6947
ASP A6912
1.59A
SFG  A7103 ( 2.7A)
None
SFG  A7103 ( 4.8A)
SFG  A7103 ( 3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6868
SER A6896
ASP A7091
1.75A
SFG  A7103 ( 3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ASP C6912
PHE C6868
SER C6896
ILE C7088
ASP C7091
1.65A
SFG  C7103 ( 3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6912
PHE C6868
SER C6896
ASP C7091
1.76A
SFG  C7103 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6947
PHE A6868
ASP A6897
1.57A
SFG  A7103 ( 3.3A)
SFG  A7103 ( 4.8A)
None
SFG  A7103 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER B 198
PHE B 195
PHE B 177
LEU B  76
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP A 240
SER A 242
CYH A 293
LEU A 255
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP B 301
SER B 208
PHE B 233
LEU B 252
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER A 198
PHE A 195
PHE A 177
LEU A  76
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP B 240
SER B 242
CYH B 293
LEU B 255
1.62A
None
None
U5P  B 401 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP A 301
SER A 208
PHE A 233
LEU A 252
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ASP A 153
PHE A 150
SER A 113
CYH A 160
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.59A
None
None
None
U5G  A 401 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6897
PHE A6868
PHE A6947
ASP A6912
1.56A
SAH  A7101 (-2.7A)
None
SAH  A7101 ( 4.8A)
SAH  A7101 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A7004
1.32A
SAH  A7101 (-3.7A)
SAH  A7101 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.63A
None
None
None
None
SAH  A7101 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
ASP A6912
PHE A6868
1.58A
None
None
None
SAH  A7101 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6928
PHE A6947
SER A6973
LEU A6978
1.76A
SAH  A7101 (-3.7A)
SAH  A7101 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
PHE A6947
SER A6973
PHE A6868
LEU A7004
1.51A
SAH  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A7091
SER A6896
ILE A7088
PHE A6868
ASP A6912
1.56A
None
None
None
None
SAH  A7101 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.59A
SAH  A7101 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6947
PHE A6868
ASP A6897
1.54A
SAH  A7101 (-3.3A)
SAH  A7101 ( 4.8A)
None
SAH  A7101 (-2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6912
PHE A6868
SER A6896
ASP A7091
1.74A
SAH  A7101 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ASP A6912
PHE A6868
SER A6896
ILE A7088
ASP A7091
1.62A
SAH  A7101 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
LEU B 103
ASP B  99
PHE B  92
ILE B 107
SER C   1
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
LEU B 103
ASP B  99
PHE B  92
ILE B 107
SER C   1
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ASP A 216
PHE A   3
CYH A 300
LEU A 253
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
SER A 262
SER A 111
CYH A 148
LEU A 152
1.68A
None
PO4  A 502 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
ASP A 302
SER A 245
CYH A 155
LEU A 172
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
SER A 262
SER A 111
CYH A 148
PHE A 147
1.68A
None
PO4  A 502 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASP A 248
SER A 254
PHE A 294
LEU A 205
1.64A22.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ASP A 428
SER C  33
PHE A 464
SER A 514
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6ym0 LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ASP E 428
SER L  33
PHE E 464
SER E 514
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASP A 248
SER A 254
PHE A 294
LEU A 205
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASP A 216
PHE A   3
CYH A 300
LEU A 253
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.69A
None
None
None
PK8  A 401 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER E 139
PHE E 116
CYH E  92
LEU E  53
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.60A
None
None
None
PJE  C   5 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 216
PHE A   3
CYH A 300
LEU A 253
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 248
SER A 254
PHE A 294
LEU A 205
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		5 / 10
LEU A 758
ASP A 760
ILE A 589
PHE A 694
ASP A 623
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 100
PHE A  70
SER A  15
PHE A   7
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 390
SER A 672
PHE A 407
LEU B 184
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 623
PHE A 694
LEU A 758
ASP A 760
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		5 / 10
LEU A 758
ASP A 760
ILE A 589
PHE A 694
ASP A 623
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
NSP7
(SARS-CoV-2)		4 / 8
SER C  15
PHE A 415
CYH A 842
LEU A 437
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		5 / 9
LEU A 758
ASP A 760
ILE A 589
PHE A 694
SER A 681
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
SER A 681
PHE A 694
LEU A 758
ASP A 760
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  45
PHE A  35
LEU A 127
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 208
SER A 236
PHE A 192
ASP A 221
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 221
SER A 236
CYH A 193
PHE A 192
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		5 / 10
LEU A 758
ASP A 760
ILE A 589
PHE A 694
SER A 681
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7btf NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  48
LEU A 207
ASP A 208
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASP A 216
PHE A   3
CYH A 300
LEU A 253
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
SER A 123
PHE A 140
SER A 147
LEU A  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 390
SER A 672
PHE A 407
LEU B 184
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
SER A 318
PHE A 275
SER A 325
LEU A 329
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  45
PHE A  35
LEU A 127
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 390
SER A 672
PHE A 407
LEU B 184
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 433
PHE A 429
PHE A 440
ASP A 833
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 236
PHE A  45
PHE A  35
LEU A 127
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 784
SER A 709
PHE A 753
LEU A 727
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 318
PHE A 275
SER A 325
LEU A 329
1.69A
None