Ligand ID: NOG


Drugbank ID:
DB00367
(Levonorgestrel)
DB09389
(Norgestrel)


Indication:
For the treatment of menopausal and postmenopausal disorders and alone or in combination with other hormones as an oral contraceptive.;Norgestrel in combination with ethinyl estradiol is indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception.

Get human targets for NOG in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'NOG' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 219
ASN A 221
MET A 276
LEU A 287
1.78A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 284
THR A 199
PHE A 291
LEU A 286
1.75A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.76A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.51A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.52A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.53A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.75A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
PHE A 103
ASN A  84
MET A 162
1.56A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
PHE A 103
ASN A  84
MET A 162
1.57A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.74A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.52A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.51A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.59A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.43A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 271
ASN A 274
LEU A 272
LEU A 205
LEU A 220
1.79A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER B 284
THR B 199
PHE B 291
LEU B 286
1.65A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 271
ASN B 274
LEU B 272
LEU B 205
LEU B 220
1.79A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A  10
ASP C 153
PHE C 150
ASN C 151
1.45A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR D 175
ASP D 176
PHE D 103
MET D 162
1.76A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR D 175
PHE D 103
ASN D  84
MET D 162
1.59A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR C 175
ASP C 176
PHE C 159
MET C 162
1.55A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR B 175
ASP B 176
PHE B 159
MET B 162
1.55A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR C 175
PHE C 103
ASN C  84
MET C 162
1.59A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A  10
PHE C 305
MET C   6
LEU A 115
1.68A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR B 225
ASP B 229
ASN B 228
LEU B 205
1.43A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR D 175
ASP D 176
PHE D 159
MET D 162
1.55A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR C 225
ASN C 228
MET C 235
LEU C 272
1.67A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 225
ASN A 228
MET A 235
LEU A 272
1.51A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A 284
THR A 199
PHE A 291
LEU A 286
1.72A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.52A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.73A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 127
GLN A 210
LEU A 241
LEU A 247
TYR A 175
1.78A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 351
GLN A 292
LEU A 470
ARG A 467
LEU A 636
1.34A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 343
THR B 124
ASN B 104
LEU B 117
1.61A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ASP A 211
ASN A 215
MET A 124
LEU A 241
1.41A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP7
(SARS-CoV-2)		5 / 12
LEU C  55
LEU C  17
LEU C  20
GLN C  19
ARG C  21
1.62A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 241
LEU A 247
TYR A 175
1.68A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 723
LEU A 727
LEU A 731
GLN A 468
LEU A 749
1.70A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  98
LEU D 103
MET D  90
LEU C  13
TYR A 420
1.79A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  95
ASN D 104
LEU D  98
LEU C  13
LEU C  60
1.77A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 672
THR B 187
MET B 129
LEU A 388
1.52A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 397
THR B 137
ASP B 134
LEU A 389
1.57A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ASP A 211
ASN A 213
MET A 124
LEU A 241
1.72A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  13
LEU C  56
MET D  94
MET D  87
CYH C   8
1.73A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 212
LEU A 247
TYR A 175
1.75A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.53A11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.42A11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER A 155
THR A 326
PHE A 195
LEU A 190
1.40A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.79A
None
None
SO4  B 201 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
SER B 139
PHE B 116
ASN B 150
LEU B 140
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.56A10.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.46A10.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.55A10.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 767
LEU B 763
GLN A1002
LEU B 962
TYR B1007
1.45A10.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
THR H  31
PHE C 374
ASN C 370
LEU C 513
1.73A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6w4h NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.36A21.59
None
None
None
None
BDF  A7105 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w4h NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.35A21.59
None
None
None
None
BDF  A7105 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
ASP B4359
PHE B4363
ASN B4358
LEU B4345
1.79A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
SER A 139
PHE A 116
ASN A 150
LEU A 140
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.66A
None
MES  B 201 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.37A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
ASP B4359
PHE B4363
ASN B4358
LEU B4345
1.75A20.92
None
None
NA  B4403 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
ASP C6904
PHE D4321
MET C6839
LEU D4298
1.41A18.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.37A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.37A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.45A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
ASP A6904
PHE B4321
MET A6839
LEU B4298
1.44A18.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7072
LEU C6959
CYH C7007
1.37A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
ASP D4359
PHE D4363
ASN D4358
LEU D4345
1.76A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.45A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 101
LEU B 117
LEU B 113
LEU B 172
CYH B 260
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 101
LEU A 117
LEU A 113
LEU A 172
CYH A 260
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 8
PHE A  90
ASN A  95
MET A 101
LEU A   9
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wcf NSP3
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.66A
None
MES  A 201 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wey NSP3
(SARS-CoV-2)		5 / 12
LEU A 247
ASN A 244
LEU A 279
LEU A 297
LEU A 257
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wiq NSP7
(SARS-CoV-2)		4 / 8
SER A  25
ASP A  38
ASN A  37
LEU A  28
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wiq NSP7
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  17
LEU A  14
LEU A  55
LEU A  60
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wiq NSP7
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  55
LEU A  56
MET A  62
LEU A  28
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  13
LEU B  91
LEU B 103
LEU A  35
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  95
LEU B 103
ASN B 104
ARG B 190
LEU A  60
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
LEU A  13
LEU A  14
LEU A  35
LEU B 103
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU F 352
LEU F 353
LEU E 331
LEU F 291
TYR F 298
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU B 352
LEU B 353
LEU A 331
LEU B 291
TYR B 298
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU D 352
LEU D 353
LEU C 331
LEU D 291
TYR D 298
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU A 352
LEU A 353
LEU B 331
LEU A 291
TYR A 298
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU C 352
LEU C 353
LEU D 331
LEU C 291
TYR C 298
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU E 352
LEU E 353
LEU F 331
LEU E 291
TYR E 298
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7072
LEU C6959
CYH C7007
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
SER C 105
THR D 148
ASN D 154
LEU C 104
1.55A
None
None
MES  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
ASP D4359
PHE D4363
ASN D4358
LEU D4345
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
ASP C6904
PHE D4321
MET C6839
LEU D4298
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7072
LEU C6959
CYH C7007
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C7010
LEU C7073
LEU C7078
LEU C6959
CYH C7007
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
ASP A6904
PHE B4321
MET A6839
LEU B4298
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER A 294
THR A 196
ASP A 324
ASN A  75
1.75A
U5P  A 401 (-2.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
LEU A 201
ASN A 200
GLN A 160
LEU A 299
LEU A 215
1.79A
EDO  A 405 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER B 155
THR B 326
ASN B  74
LEU B 190
1.54A
EDO  B 404 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
SER A 155
THR A 326
ASN A  74
LEU A 190
1.48A
None
None
EDO  A 406 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 139
PHE A 116
ASN A 150
LEU A 140
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C  43
ASN C  40
LEU C  75
LEU C  93
LEU C  53
1.68A
None
APR  C 201 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER B 139
PHE B 116
ASN B 150
LEU B 140
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D  43
ASN D  40
LEU D  75
LEU D  93
LEU D  53
1.70A
None
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.73A
None
APR  A 201 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER C 139
PHE C 116
ASN C 150
LEU C 140
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER D 139
PHE D 116
ASN D 150
LEU D 140
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.68A
None
APR  B 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7072
LEU A6959
CYH A7007
1.32A
None
None
None
None
8NK  A7103 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.47A
None
None
None
None
8NK  A7103 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7010
LEU A7073
LEU A7078
LEU A6959
CYH A7007
1.38A
None
None
None
None
8NK  A7103 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
LEU A  13
LEU A  14
LEU A  35
LEU B 103
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  55
LEU C  56
MET C  62
LEU C  28
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU C  20
LEU C  17
LEU C  14
MET C  52
LEU C  60
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  17
LEU A  14
LEU A  35
LEU A  60
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  17
LEU C  20
LEU C  60
LEU C  35
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D 103
ASN D 100
LEU D  95
LEU C  55
LEU D 122
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  59
LEU C  60
LEU D  95
LEU C  14
CYH C  32
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  17
LEU A  20
LEU A  60
LEU A  35
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  13
LEU D  91
LEU D 103
LEU C  35
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  95
LEU B 103
ASN B 104
ARG B 190
LEU A  60
1.75A
None
None
None
EDO  B 302 (-2.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  91
LEU C  13
LEU C  14
LEU C  35
LEU D 103
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  17
LEU A  14
MET A  52
LEU A  60
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  13
LEU B  91
LEU B 103
LEU A  35
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  95
LEU D 103
ASN D 104
ARG D 190
LEU C  60
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  95
LEU B 103
ASN B 104
ARG B 190
LEU A  60
1.66A
None
None
None
EDO  B 302 (-2.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU A  59
LEU A  60
LEU B  95
LEU A  14
CYH A  32
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wqd NSP7
(SARS-CoV-2)		5 / 12
LEU C  20
LEU C  17
LEU C  14
LEU C  35
LEU C  60
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  10
THR B  93
MET B  90
LEU C  40
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 199
ASP A 289
MET A 276
LEU A 272
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 225
ASN A 228
MET A 235
LEU A 272
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 219
ASN A 221
MET A 276
LEU A 287
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A 101
LEU A 117
LEU A 113
LEU A 172
CYH A 260
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
ASP A  12
PHE A  79
MET A  84
LEU A  58
1.72A
 CL  A 506 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER B  10
ASP A 153
PHE A 150
ASN A 151
1.29A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.77A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.51A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU B  95
LEU B 103
ASN B 104
ARG B 190
LEU A  60
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  13
LEU B  91
LEU B 103
LEU A  35
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU B  91
LEU A  13
LEU A  14
LEU A  35
LEU B 103
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  59
LEU A  60
LEU B  95
LEU A  14
CYH A  32
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  17
LEU C  20
LEU C  60
LEU C  35
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU D  95
LEU D 103
ASN D 104
ARG D 190
LEU C  60
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  55
LEU A  56
MET A  62
LEU A  28
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  14
LEU A  17
LEU A  20
LEU A  60
LEU A  35
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  17
LEU A  14
MET A  52
LEU A  60
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  59
LEU A  60
MET A  52
LEU B  91
LEU A  14
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  20
LEU C  17
LEU C  14
LEU C  35
LEU C  60
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
SER C  25
ASP C  38
ASN C  37
LEU C  28
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  59
LEU A  60
LEU B  95
CYH A  32
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU D  91
LEU C  13
LEU C  14
LEU C  35
LEU D 103
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  20
LEU A  17
LEU A  14
LEU A  35
LEU A  60
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU B  95
LEU B 103
ASN B 104
ARG B 190
LEU A  60
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU D  98
LEU D 103
ASN D 104
ARG D 190
LEU C  13
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU D 103
ASN D 100
LEU D  95
LEU C  55
LEU D 122
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU B  98
LEU B 103
ASN B 104
ARG B 190
LEU A  13
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  13
LEU D  91
LEU D 103
LEU C  35
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU D  95
LEU D 103
ASN D 104
ARG D 190
LEU C  60
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 284
THR A 199
PHE A 291
LEU A 286
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 284
THR A 199
PHE A 291
LEU A 286
1.73A
None
PEG  A 404 (-3.0A)
CL  A 406 (-4.4A)
PEG  A 404 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PHE A 219
ASN A 221
MET A 276
LEU A 287
1.75A
None
None
None
PEG  A 404 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER D 139
PHE D 116
ASN D 150
LEU D 140
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  43
ASN D  40
LEU D  75
LEU D  93
LEU D  53
1.68A
None
EDO  D 206 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  43
ASN C  40
LEU C  75
LEU C  93
LEU C  53
1.69A
None
None
EPE  C 202 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  43
ASN E  40
LEU E  75
LEU E  93
LEU E  53
1.70A
None
EPE  E 202 (-4.1A)
EPE  E 203 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  43
ASN E  40
LEU E  75
LEU E  93
LEU E  53
1.69A
None
APR  E 201 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  43
ASN D  40
LEU D  75
LEU D  93
LEU D  53
1.67A
None
APR  D 201 (-3.7A)
EDO  D 202 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.67A
None
APR  B 201 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.71A
None
APR  A 201 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  43
ASN C  40
LEU C  75
LEU C  93
LEU C  53
1.68A
None
APR  C 201 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  43
ASN B  40
LEU B  75
LEU B  93
LEU B  53
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER B 139
PHE B 116
ASN B 150
LEU B 140
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  43
ASN C  40
LEU C  75
LEU C  93
LEU C  53
1.74A
None
MES  C 201 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  43
ASN A  40
LEU A  75
LEU A  93
LEU A  53
1.74A
None
MES  A 201 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 225
ASP A 229
ASN A 228
LEU A 205
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 211
ASN A 215
MET A 124
LEU A 241
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 723
LEU A 727
LEU A 731
GLN A 468
LEU A 749
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 178
LEU A 146
MET A 124
LEU A 131
LEU A 245
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 343
THR B 124
ASN B 104
LEU B 117
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 672
THR B 187
MET B 129
LEU A 388
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 211
ASN A 213
MET A 124
LEU A 241
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 351
GLN A 292
LEU A 470
ARG A 467
LEU A 636
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  10
PHE C  49
ASN D 104
LEU C  13
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
THR A 123
ASN A 215
MET A 124
LEU A 241
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 212
LEU A 247
TYR A 175
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  13
LEU D  91
LEU D 103
LEU C  35
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 241
LEU A 247
TYR A 175
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 159
MET A 162
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
ASP A 176
PHE A 103
MET A 162
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
THR A 175
PHE A 103
ASN A  84
MET A 162
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 723
LEU A 727
LEU A 731
GLN A 468
LEU A 749
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 672
THR B 187
MET B 129
LEU A 388
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  91
LEU C  13
LEU C  14
LEU C  35
LEU D 103
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  13
LEU D  91
LEU D 103
LEU C  35
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  10
PHE C  49
ASN D 104
LEU C  13
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 212
LEU A 247
TYR A 175
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 241
LEU A 247
TYR A 175
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 8
THR A 123
ASP A 211
ASN A 215
MET A 124
LEU A 241
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 351
GLN A 292
LEU A 470
ARG A 467
LEU A 636
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP7
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  55
LEU C  56
MET C  62
LEU C  28
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 178
LEU A 146
MET A 124
LEU A 131
LEU A 245
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 377
PHE A 340
MET B  94
LEU B 103
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 241
LEU A 247
TYR A 175
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 723
LEU A 727
LEU A 731
GLN A 468
LEU A 749
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP7
(SARS-CoV-2)		5 / 12
LEU C  14
LEU C  55
LEU C  56
MET C  62
LEU C  28
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 672
THR B 187
MET B 129
LEU A 388
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 142
LEU A 127
LEU A 212
LEU A 247
TYR A 175
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
SER A 397
THR B 137
ASP B 134
LEU A 389
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ASP A 211
ASN A 215
MET A 124
LEU A 241
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP7
(SARS-CoV-2)		5 / 12
LEU C  20
LEU C  17
LEU C  14
LEU C  55
LEU C  60
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 351
GLN A 292
LEU A 470
ARG A 467
LEU A 636
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 186
LEU A 241
LEU A 240
LEU A 316
MET A 463
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 377
PHE A 340
MET B  94
LEU B 103
1.66A
None