Ligand ID: NBO


Drugbank ID:
DB00461
(Nabumetone)


Indication:
For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Get human targets for NBO in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'NBO' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.49A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.52A13.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.49A17.61
None
None
None
DMS  A 403 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
THR A 292
1.53A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 169
GLY A 170
GLY A 174
THR A 175
1.45A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A 183
PRO A 184
GLY A 195
THR A 196
1.62A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.45A17.61
None
DMS  A 403 (-3.8A)
DMS  A 403 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6lu7 MAIN PROTEASE

(SARS-CoV-2;
synthetic
construct)		4 / 7
ALA A 173
GLU A 166
LYS C   2
LEU C   4
1.55A18.27
None
PJE  C   5 ( 3.9A)
02J  C   1 ( 3.0A)
PJE  C   5 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.41A23.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 190
PRO A 184
GLY A 195
THR A 196
1.47A23.82
DMS  A 401 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.42A23.82
None
None
None
DMS  A 403 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.43A23.82
None
DMS  A 403 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.53A18.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.53A18.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.41A23.76
None
None
None
DMS  A 401 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 190
PRO A 184
GLY A 195
THR A 196
1.43A23.76
DMS  A 402 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A23.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.45A23.76
None
DMS  A 401 (-4.3A)
DMS  A 401 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR D 135
PRO D 132
ASN D 133
GLY D 109
1.40A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR C 135
PRO C 132
ASN C 133
GLY C 109
1.42A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLY C 120
PRO C 122
ASN C  28
GLY C  15
1.40A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR B 135
PRO B 132
ASN B 133
GLY B 109
1.45A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLY D 120
PRO D 122
ASN D  28
GLY D  15
1.39A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE C 150
VAL C 148
GLY C 149
CYH C 160
LEU C  30
1.51A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR B  98
GLY B  15
ASN B  95
GLY B  29
1.45A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.43A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.55A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.47A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR A 169
GLY A 170
GLY A 174
THR A 175
1.40A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.47A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.51A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLY A 503
ASN A 507
TYR A 515
THR A 567
1.41A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLY A 352
TYR A 346
GLY A 345
THR A 344
1.23A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN A  75
TYR A 179
VAL A  78
GLY A  77
LEU A  73
1.54A21.42
None
None
None
GOL  A 404 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
GLY C 404
PRO C 507
TYR C 495
GLY C 496
1.58A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR C 376
TYR H  52
GLY H  97
THR H 100
1.42A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
GLY H  95
TYR L  91
GLY C 381
THR C 430
1.67A18.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR H  31
GLY H  95
GLY C 381
THR C 430
1.67A18.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR C 376
GLY H  53
GLY H  97
THR H 100
1.03A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w4h NSP16
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.25A23.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w61 NSP10
(SARS-CoV-2)		4 / 7
GLY B4288
PRO B4290
GLY B4362
THR B4364
1.77A16.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6993
ASN A6996
GLY A6879
THR A6880
1.37A
None
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w61 NSP10
(SARS-CoV-2)		4 / 7
THR B4364
GLY B4362
PRO B4360
THR B4355
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6880
GLY A6879
PRO A6878
GLY A6875
1.53A18.55
None
SAM  A7104 (-3.6A)
SAM  A7104 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 169
GLY A 170
GLY A 174
THR A 175
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.52A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
THR A  13
ASN A  15
TYR A  17
THR B  13
1.69A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
THR B  13
ASN B  15
TYR B  17
THR A  13
1.79A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR C6880
GLY C6879
PRO C6878
GLY C6875
1.52A18.84
None
SAM  C7105 ( 3.4A)
SAM  C7105 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR C6889
GLY C6890
GLY C7054
THR C7055
1.29A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR A6993
ASN A6996
GLY A6879
THR A6880
1.35A18.84
None
FMT  A7104 ( 3.3A)
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR A6880
GLY A6879
PRO A6878
GLY A6875
1.54A18.84
None
SAM  A7102 ( 3.4A)
SAM  A7102 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.31A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP10
(SARS-CoV-2)		4 / 7
GLY D4288
PRO D4290
GLY D4362
THR D4364
1.74A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
THR C6993
ASN C6996
GLY C6879
THR C6880
1.34A18.84
None
FMT  C7108 ( 3.4A)
SAM  C7105 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6w75 NSP10
(SARS-CoV-2)		4 / 7
GLY B4288
PRO B4290
GLY B4362
THR B4364
1.74A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ASP B 286
ALA B 288
LYS B 105
LEU B 118
1.78A19.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
ASP C 286
ALA C 288
LYS C 105
LEU C 118
1.78A19.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6wiq NSP7
(SARS-CoV-2)		4 / 7
ASP A  38
ALA A  48
LYS A   7
LEU A  55
1.76A12.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY D 287
TYR D 298
GLY D 295
THR D 265
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY F 287
TYR F 298
GLY F 295
THR F 265
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY C 287
TYR C 298
GLY C 295
THR C 265
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY A 287
TYR A 298
GLY A 295
THR A 265
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR A 282
GLY B 335
GLY A 275
THR A 271
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY B 287
TYR B 298
GLY B 295
THR B 265
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR C 282
GLY D 335
GLY C 275
THR C 271
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR F 282
GLY E 335
GLY F 275
THR F 271
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY E 287
TYR E 298
GLY E 295
THR E 265
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR C6993
ASN C6996
GLY C6879
THR C6880
1.34A
None
None
SAH  C7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR C6889
GLY C6890
GLY C7054
THR C7055
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.35A
 NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6993
ASN A6996
GLY A6879
THR A6880
1.34A
None
None
SAH  A7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR C 165
GLY C  71
PRO C  73
THR C  54
1.35A
None
None
None
MES  D 201 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR A 165
GLY A  71
PRO A  73
THR A  54
1.41A
None
None
None
MES  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR D 165
GLY D  71
PRO D  73
THR D  54
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY D 124
PRO D 122
GLY D 114
THR D 115
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY C 124
PRO C 122
GLY C 114
THR C 115
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR B 165
GLY B  71
PRO B  73
THR B  54
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
GLY B 124
PRO B 122
GLY B 114
THR B 115
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkq NSP16
(SARS-CoV-2)		4 / 7
THR A6993
ASN A6996
GLY A6879
THR A6880
1.34A
None
None
SFG  A7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkq NSP16
(SARS-CoV-2)		4 / 7
THR C6889
GLY C6890
GLY C7054
THR C7055
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkq NSP16
(SARS-CoV-2)		4 / 7
THR C6993
ASN C6996
GLY C6879
THR C6880
1.33A
None
None
SFG  C7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wkq NSP16
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN A  75
TYR A 179
VAL A  78
GLY A  77
LEU A  73
1.60A21.18
None
None
None
EDO  A 406 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN B  75
TYR B 179
VAL B  78
GLY B  77
LEU B  73
1.59A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A 183
PRO A 184
GLY A 195
THR A 196
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.52A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wq3 NSP10
(SARS-CoV-2)		4 / 7
THR B4364
GLY B4362
PRO B4360
THR B4355
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6993
ASN A6996
GLY A6879
THR A6880
1.39A
None
GTA  A7102 (-3.9A)
SAH  A7101 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
THR A6889
GLY A6890
GLY A7054
THR A7055
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6wqd NSP7
(SARS-CoV-2)		4 / 7
ASP A  38
ALA A  48
LYS A   7
LEU A  55
1.77A12.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 169
GLY A 170
GLY A 174
THR A 175
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
ASP A 286
ALA A 288
LYS A 105
LEU A 118
1.78A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
THR A 292
1.53A17.61
None
DMS  A 404 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.53A13.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.49A17.61
None
None
None
DMS  A 406 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.47A17.61
None
DMS  A 406 (-3.7A)
DMS  A 406 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLY A 183
PRO A 184
GLY A 195
THR A 196
1.63A17.61
None
None
DMS  A 404 ( 4.4A)
DMS  A 404 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A17.61
None
DMS  A 404 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A 169
GLY A 170
GLY A 174
THR A 175
1.50A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
THR A 125
GLY A  31
PRO A  33
THR A  14
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A  84
PRO A  82
GLY A  74
THR A  75
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
THR A   9
GLY A  76
TYR A  71
GLY A  45
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR E 376
GLY H  54
GLY H 101
THR H 104
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR A 376
TYR B  52
GLY B 101
THR B 104
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLY A 404
PRO A 507
TYR A 495
GLY A 496
1.48A
DMS  A 903 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR A 376
GLY B  54
GLY B 101
THR B 104
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR E 376
GLY H  54
GLY H 101
THR H 104
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR E 376
TYR H  52
GLY H 101
THR H 104
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR E 376
GLY H  54
GLY H 101
THR H 104
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR A 376
GLY B  54
GLY B 101
THR B 104
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.52A18.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.45A
None
None
None
PEG  A 405 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE

(SARS-CoV-2;
synthetic
construct)		4 / 7
ALA A 173
GLU A 166
LYS C   2
LEU C   4
1.53A18.27
None
PJE  C   5 (-3.7A)
02J  C   1 ( 2.9A)
PJE  C   5 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.52A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7btf NSP8
(SARS-CoV-2)		4 / 7
THR B 137
ASN B 140
GLY B 144
THR B 145
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLY A 352
TYR A 346
GLY A 345
THR A 344
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLY A 503
ASN A 507
TYR A 515
THR A 567
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		7btf NSP7
(SARS-CoV-2)		4 / 7
ASP C  38
ALA C  42
LYS C   7
LEU C  35
1.71A8.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
THR A  98
GLY A  15
ASN A  95
GLY A  29
1.44A
None
DMS  A 403 (-3.7A)
DMS  A 403 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
GLY A 120
PRO A 122
ASN A  28
GLY A  15
1.40A
None
None
None
DMS  A 403 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
THR A 135
PRO A 132
ASN A 133
GLY A 109
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
THR A 190
PRO A 184
GLY A 195
THR A 196
1.46A
DMS  A 405 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 150
VAL A 148
GLY A 149
CYH A 160
LEU A  30
1.53A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLY A 352
TYR A 346
GLY A 345
THR A 344
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ASN A 790
ALA A 625
LYS A 621
LEU A 786
1.79A20.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLY A 352
TYR A 346
GLY A 345
THR A 344
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ASN A 790
ALA A 625
LYS A 621
LEU A 786
1.79A20.40
None