Ligand ID: MXD


Drugbank ID:
DB00350
(Minoxidil)


Indication:
For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.

Get human targets for MXD in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'MXD' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.63A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.70A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.60A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.41A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.65A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.54A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 6
ALA B 956
LEU B 959
ALA C 958
THR C 961
ASN C 960
1.63A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.52A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.55A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.56A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.56A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.55A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.52A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR B 209
ALA B 206
LEU B 250
THR B 243
1.39A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.56A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA C 206
LEU C 250
THR C 243
ASN C 231
1.57A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR C 209
ALA C 206
LEU C 250
THR C 243
1.45A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA D 206
LEU D 250
THR D 243
ASN D 231
1.60A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.59A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR D 209
ALA D 206
LEU D 250
THR D 243
1.47A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA B 206
LEU B 205
THR B 243
ASN B 231
1.60A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA C 206
LEU C 250
THR C 243
ASN C 231
1.61A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA B 206
LEU B 250
THR B 243
ASN B 231
1.61A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA B 206
LEU B 250
THR B 243
ASN B 231
1.57A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.59A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.41A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 382
LEU A 401
THR A 540
ASN A 507
1.58A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m71 NSP12
(SARS-CoV-2)		4 / 6
TYR A 884
ALA A 866
LEU A 862
ALA A 840
1.53A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6m71 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.47A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m71 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.47A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6m71 NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.42A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 127
ALA A  38
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
ALA C  55
LEU C  56
ALA C 173
THR D  76
1.48A14.87
MES  C 204 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
ALA A  55
LEU A  56
ALA A 173
THR B  76
1.41A14.87
MES  A 203 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ALA A6832
LEU A6834
ALA A6843
THR A6846
1.71A16.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ALA A6832
LEU A6834
ALA A6843
THR A6846
1.70A16.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
THR B 149
ASN B  15
1.70A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ALA B  39
LEU B  43
THR B  57
ASN B  59
1.61A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ALA A 129
LEU A 127
ALA A  38
ASN A  40
1.79A15.76
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ALA A  39
LEU A  43
THR A  57
ASN A  59
1.64A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.73A15.76
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 127
ALA A 124
1.66A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.46A
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 127
ALA B  38
1.77A15.76
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 127
ALA B  38
1.63A15.76
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 127
ALA A  38
1.78A15.76
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.76A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ALA A  39
LEU A  43
THR A  57
ASN A  59
1.69A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 127
ALA A  38
1.62A15.76
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
THR A 149
ASN A  15
1.73A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 127
ALA B 124
1.64A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ALA B  39
LEU B  43
THR B  57
ASN B  59
1.64A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ALA C6832
LEU C6834
ALA C6843
THR C6846
1.74A14.84
FMT  C7111 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ALA A6832
LEU A6834
ALA A6843
THR A6846
1.70A14.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ALA C6832
LEU C6834
ALA C6843
THR C6846
1.74A14.84
FMT  C7111 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ALA A6832
LEU A6834
ALA A6843
THR A6846
1.70A14.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR C  83
ALA C 149
LEU C 150
ALA C 135
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR B  83
ALA B 149
LEU B 150
ALA B 135
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A  83
ALA A 149
LEU A 150
ALA A 135
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR C 136
ALA C 139
ALA C 116
THR C 115
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR B  83
ALA B 149
LEU B 150
ALA B 135
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA B 116
LEU B 117
THR B  90
ASN B 146
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR B 136
ALA B 139
ALA B 116
THR B 115
1.55A
None
None
None
CL  B 502 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR C  83
ALA C 149
LEU C 150
ALA C 135
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A  39
LEU A  36
THR A   9
ASN A  13
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C 114
LEU C 117
ALA C 144
ASN C 146
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C 116
LEU C 117
THR C  90
ASN C 146
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA B 116
LEU B 117
THR B  90
ASN B 146
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR C 136
ALA C 139
ALA C 116
THR C 115
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C 116
LEU C 117
THR C  90
ASN C 146
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C 114
LEU C 117
ALA C 144
ASN C 146
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A  83
ALA A 149
LEU A 150
ALA A 135
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 136
ALA A 139
ALA A 116
THR A 115
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 116
LEU A 117
THR A  90
ASN A 146
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR B 136
ALA B 139
ALA B 116
THR B 115
1.53A
None
None
None
CL  B 502 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 116
LEU A 117
THR A  90
ASN A 146
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 136
ALA A 139
ALA A 116
THR A 115
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 6
TYR A  31
ALA A  43
LEU A  45
ALA A  28
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 6
TYR A  31
ALA A  43
LEU A  45
ALA A  28
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 6
TYR A  89
LEU A  69
ALA A  54
ASN A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wcf NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wcf NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wcf NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 127
ALA A  38
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
TYR A 317
ALA A 316
LEU A 313
ALA A 333
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
TYR A 317
ALA A 316
LEU A 313
ALA A 338
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
TYR A 317
ALA A 316
LEU A 331
ALA A 242
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
TYR A 317
ALA A 316
LEU A 313
ALA A 338
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA E 308
ALA C 267
THR C 265
ASN C 269
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA F 311
ALA C 267
THR C 265
ASN C 269
1.59A
 CL  E 401 ( 4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA E 308
ALA C 267
THR C 265
ASN C 269
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA F 311
ALA C 267
THR C 265
ASN C 269
1.54A
 CL  E 401 ( 4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA B 305
ALA E 267
THR E 265
ASN E 269
1.58A
 CL  B 401 ( 4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 111
ALA C  50
ALA C  55
THR C  57
1.55A
None
None
MES  D 201 (-3.3A)
ZN  D 202 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 129
1.52A
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.50A
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 129
1.49A
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.51A
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
ALA C  42
LEU C  41
ALA B  86
THR B  89
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP8
(SARS-CoV-2)		4 / 6
ALA B 188
LEU B 189
ALA B 126
THR B 123
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP8
(SARS-CoV-2)		4 / 6
ALA D 188
LEU D 189
ALA D 126
THR D 123
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
ALA C  42
LEU C  41
ALA B  86
THR B  89
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
ALA A  42
LEU A  41
ALA D  86
THR D  89
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
ALA A  42
LEU A  41
ALA D  86
THR D  89
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
TYR A 136
ALA A 139
ALA A 116
THR A 115
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A 116
LEU A 117
THR A  90
ASN A 146
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A 114
LEU A 117
ALA A 144
ASN A 146
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
TYR A  83
ALA A 149
LEU A 150
ALA A 135
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A 116
LEU A 117
THR A  90
ASN A 146
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A 114
LEU A 117
ALA A 144
ASN A 146
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.66A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.61A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 234
ALA A 266
THR A 224
ASN A 221
1.68A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.70A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 234
ALA A 266
THR A 224
ASN A 221
1.67A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.63A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.54A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
ALA A  42
LEU A  41
ALA D  86
THR D  89
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
ALA C  42
LEU C  41
ALA B  86
THR B  89
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
ALA C  42
LEU C  41
ALA B  86
THR B  89
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
ALA A  42
LEU A  41
ALA D  86
THR D  89
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 129
1.47A
None
None
EDO  D 204 ( 4.5A)
EDO  D 205 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.54A
None
None
None
EDO  C 208 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.43A
None
None
None
EDO  C 208 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.39A
None
None
EDO  D 204 ( 4.5A)
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 127
ALA D  38
1.58A
None
None
None
EDO  D 205 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.50A
None
None
EDO  D 204 ( 4.5A)
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 127
ALA B  38
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 134
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 134
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 129
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 134
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 129
1.50A
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.52A
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 129
1.51A
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 129
1.53A
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.44A
None
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.55A
None
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.51A
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR E 113
ALA E 112
LEU E 109
ALA E 134
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR D 113
ALA D 112
LEU D 109
ALA D 134
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 129
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 127
ALA C  38
1.60A
None
None
None
MES  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.38A
None
None
None
EDO  A 205 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 134
1.51A
None
None
None
EDO  A 205 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR A 113
ALA A 112
LEU A 109
ALA A 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 129
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR C 113
ALA C 112
LEU C 109
ALA C 134
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.48A
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 127
ALA B  38
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
TYR B 113
ALA B 112
LEU B 109
ALA B 134
1.37A
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 250
THR A 243
ASN A 231
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 382
LEU A 401
THR A 540
ASN A 507
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 382
LEU A 401
THR A 540
ASN A 507
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 866
LEU A 862
ALA A 840
ASN A 416
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 356
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7btf NSP8
(SARS-CoV-2)		4 / 6
ALA D 188
LEU D 128
THR D 141
ASN D 105
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 206
LEU A 205
THR A 243
ASN A 231
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 250
THR A 243
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
TYR A 209
ALA A 206
LEU A 205
ASN A 221
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 382
LEU A 401
THR A 540
ASN A 507
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 356
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
TYR A 374
ALA A 375
THR A 531
ASN A 534
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
TYR A 748
LEU A 749
THR A 701
ASN A 781
1.48A
None