Ligand ID: K4D


Drugbank ID:
DB01195
(Flecainide)


Indication:
Flecainide is is a class Ic antiarrhythmic agent and as such, it is used for the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.

Get human targets for K4D in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'K4D' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		5r81 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.42A21.98
None
RZJ  A1001 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.74A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.42A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.45A22.22

None
DMS  A 401 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.76A22.22

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.76A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.54A21.98

None
N0A  D   2 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.57A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
MET C  82
LEU C  87
THR C 175
LEU C  30
1.71A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU C  27
MET C 165
THR C 175
LEU C  30
1.51A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR C 201
LEU C 242
MET C 264
LEU C 232
1.77A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU D  27
MET D 165
THR D 175
LEU D  30
1.47A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
MET B  82
LEU B  87
THR B 175
LEU B  30
1.71A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR B 201
LEU B 242
MET B 264
LEU B 232
1.75A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.74A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU B  27
MET B 165
THR B 175
LEU B  30
1.48A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.66A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.49A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR D 201
LEU D 242
MET D 264
LEU D 232
1.74A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
MET D  82
LEU D  87
THR D 175
LEU D  30
1.68A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.49A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.78A21.98

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
THR A 870
LEU A 869
THR A 912
LEU A 883
1.60A14.74

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
THR A 248
LEU A 247
THR A 252
LEU A 316
1.55A14.74

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.26A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.29A18.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
THR A6846
LEU B4298
MET A6840
THR A6993
1.67A18.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.47A
X77  A 401 ( 3.9A)
X77  A 401 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.22A19.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 6
THR A6846
LEU B4298
MET A6840
THR A6993
1.67A19.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
THR C6880
LEU C6883
THR C6908
LEU C6892
1.26A19.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
THR B 115
LEU B 113
MET B 169
LEU B 162
1.69A
 CL  B 502 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
MET C 169
THR C 168
THR C 115
LEU C 162
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
MET A 169
THR A 168
THR A 115
LEU A 162
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 115
LEU A 113
MET A 169
LEU A 162
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
MET B 169
THR B 168
THR B 115
LEU B 162
1.32A
None
None
CL  B 502 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
THR C 115
LEU C 113
MET C 169
LEU C 162
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
THR A6846
LEU B4298
MET A6840
THR A6993
1.67A
None
FMT  B4403 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR C6880
LEU C6883
THR C6908
LEU C6892
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
THR C6846
LEU D4298
MET C6840
THR C6993
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR C6880
LEU C6883
THR C6908
LEU C6892
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 6
THR A6846
LEU B4298
MET A6840
THR A6993
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR A6908
LEU A6909
THR A6880
LEU A6898
1.48A
None
None
None
SFG  A7103 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR C6908
LEU C6909
THR C6880
LEU C6898
1.49A
None
None
None
SFG  C7103 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.49A
U5G  A 401 ( 4.0A)
U5G  A 401 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A6880
LEU A6883
THR A6908
LEU A6892
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
MET A 169
THR A 168
THR A 115
LEU A 162
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.76A20.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.43A20.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
MET D  94
LEU D  98
MET B  94
LEU C  55
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.60A
PK8  A 401 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.49A
PJE  C   5 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
THR A 189
LEU A 186
THR A 206
LEU A 212
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
THR A 201
LEU A 242
MET A 264
LEU A 232
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
MET A  82
LEU A  87
THR A 175
LEU A  30
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A  27
MET A 165
THR A 175
LEU A  30
1.45A
None
JRY  A 401 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
THR A 870
LEU A 869
THR A 912
LEU A 883
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
THR A 189
LEU A 186
THR A 206
LEU A 212
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
THR A 248
LEU A 247
THR A 252
LEU A 316
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
THR A 870
LEU A 869
THR A 912
LEU A 883
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
THR A 248
LEU A 247
THR A 252
LEU A 316
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
THR A 189
LEU A 186
THR A 206
LEU A 212
1.78A
None