Ligand ID: FVT


Drugbank ID:
DB00855
(Aminolevulinic acid)


Indication:
Aminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.

Get human targets for FVT in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'FVT' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A 297
GLN A 110
PRO A 293
ILE A 249
1.79A17.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.53A17.01
None
DMS  A 402 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6lvn SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 6
VAL D  22
ASN D  25
ASN C  25
GLU C  28
1.61A8.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 8
VAL D 951
ASN D 955
GLN F 957
ASN F 960
1.28A14.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.73A20.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.80A20.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.57A20.91
None
DMS  A 402 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m03 MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.49A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.73A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.56A20.24
None
DMS  A 404 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
VAL B 204
ASN B 203
ILE B 200
GLU B 240
1.71A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL B  13
GLN B 127
PRO B   9
ILE B 152
1.60A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL B 204
ASN B 203
ILE B 200
GLU B 240
1.79A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR D 209
VAL D 261
PRO D 293
ILE D 249
1.80A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL D  13
GLN D 127
PRO D   9
ILE D 152
1.56A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.55A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL C  13
GLN C 127
PRO C   9
ILE C 152
1.51A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 209
VAL A 261
PRO A 293
ILE A 249
1.76A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.52A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
VAL C 159
PRO C  74
ILE C  75
GLU B 137
1.56A14.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 458
ASN A 168
PRO A 169
ILE A 171
1.78A19.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 453
VAL A 667
ASN A 459
PRO A 677
1.74A19.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN C1023
GLN C 774
ASN C 777
GLU C 773
0.86A16.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
VAL B 166
GLN B 202
ASN B 200
GLU B 203
1.19A22.66
None
None
GOL  B 402 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN C1023
GLN C 774
ASN C 777
GLU C 773
1.15A17.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN B1023
GLN B 774
ASN B 777
GLU B 773
1.06A17.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.67A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.74A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.53A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR C  71
ASN C  13
ASN C 146
GLU C 143
1.45A19.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A  71
ASN A  13
ASN A 146
GLU A 143
1.38A19.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
TYR A 317
VAL A 351
ASN A 321
ASN A 319
1.79A17.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
TYR A 213
VAL A 234
ASN A 208
ASN A 354
1.78A17.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ASN A  83
PRO A 112
ILE A 100
GLU A 114
1.72A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
VAL A 142
GLN A 176
PRO A  68
ILE A  72
1.73A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
VAL B 142
GLN B 176
PRO B  68
ILE B  72
1.71A22.35
None
ACT  B 407 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
VAL A 166
GLN A 202
ASN A 200
GLU A 203
1.38A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
TYR B 179
GLN B 160
PRO B  68
GLU B  69
1.71A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
VAL B 166
GLN B 202
ASN B 200
GLU B 203
1.19A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.54A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wqd NSP8
(SARS-CoV-2)		4 / 8
VAL D 186
GLN D 168
ILE D 172
GLU D 171
1.70A13.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wqd NSP8
(SARS-CoV-2)		4 / 8
VAL B 186
GLN B 168
ILE B 172
GLU B 171
1.72A13.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.49A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6y84 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.67A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.59A17.22
None
DMS  A 403 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
TYR B 149
VAL A  53
ASN B 118
ILE B 119
1.70A12.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A  47
GLN A  43
ASN A  35
ILE A  34
1.72A14.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.53A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.71A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.46A20.61
None
CL  A 406 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A  95
ASN A 115
ASN A 117
GLU D 114
1.69A17.23
None
EDO  D 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL D  95
ASN D 115
ASN D 117
GLU A 114
1.64A17.23
None
EDO  D 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL D  95
ASN D 115
ASN D 117
GLU A 114
1.70A17.23
None
EDO  D 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A  95
ASN A 115
ASN A 117
GLU D 114
1.62A17.23
None
EDO  D 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL D  95
ASN D 115
ASN D 117
GLU A 114
1.71A17.23
None
EDO  A 207 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A  95
ASN A 115
ASN A 117
GLU D 114
1.64A17.23
None
EDO  A 207 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL D  95
ASN D 115
ASN D 117
GLU A 114
1.63A17.23
None
EDO  A 207 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A  95
ASN A 115
ASN A 117
GLU D 114
1.72A17.23
None
EDO  A 207 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A  95
ASN A 115
ASN A 117
GLU C 114
1.62A17.23
None
EDO  A 202 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C  95
ASN C 115
ASN C 117
GLU A 114
1.64A17.23
None
EDO  A 202 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A  95
ASN A 115
ASN A 117
GLU C 114
1.68A17.23
None
EDO  A 202 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL C  95
ASN C 115
ASN C 117
GLU A 114
1.71A17.23
None
EDO  A 202 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.79A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.71A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.54A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.80A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
VAL A  13
GLN A 127
PRO A   9
ILE A 152
1.55A20.61
None
DMS  A 406 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 204
ASN A 203
ILE A 200
GLU A 240
1.72A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 453
VAL A 667
ASN A 459
PRO A 677
1.77A18.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 315
ASN A 312
GLN A 468
ILE A 466
1.59A18.93
None