Ligand ID: FCN


Drugbank ID:
DB00828
(Fosfomycin)


Indication:
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.

Get human targets for FCN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'FCN' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
ILE A 136
SER A 147
1.42A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A  29
GLY A 143
SER A 144
1.35A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 215
ILE A 213
GLY A   2
SER A   1
1.59A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
ILE A 136
SER A 147
1.45A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 172
ILE A 136
GLY A 146
SER A 144
1.25A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 138
HIS A 163
ILE A 136
GLY A 170
1.35A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 170
GLY A 138
ILE A 136
THR A 135
1.48A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.72A24.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 120
GLY A 146
SER A 144
SER A 147
1.36A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 138
ILE A 136
SER A 147
SER A 144
1.71A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
1.49A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 251
ILE A 213
SER A 254
THR A 257
1.71A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 120
GLY A 143
SER A 144
1.44A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.76A20.24
None
None
ELL  D   3 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.77A22.04

None
None
ELL  D   3 (-3.7A)
ELL  D   3 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.76A22.04

DMS  A 403 ( 4.1A)
DMS  A 403 ( 4.8A)
ELL  D   3 ( 3.6A)
ELL  D   3 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.76A20.48
None
None
ELL  D   3 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
GLU A 166
1.61A22.04

DMS  A 403 ( 4.1A)
DMS  A 403 ( 4.8A)
ELL  D   3 (-4.5A)
ELL  D   3 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 163
ILE A 136
GLY C   2
SER C   1
1.23A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY C   2
GLY A 138
HIS A 163
GLY A 170
SER C   1
1.69A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY B 170
GLY D 215
GLY D   2
SER D   1
1.21A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR D 118
LEU D 141
HIS D 172
GLU D 166
1.55A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY D   2
GLY B 138
HIS B 163
GLY B 170
SER D   1
1.68A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C   2
GLY A 138
HIS A 172
ILE A 136
1.25A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY B 146
GLY B 174
HIS B 163
ILE B 136
GLY B 149
1.72A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.72A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR C 118
LEU C 141
HIS C 172
GLU C 166
1.62A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY D   2
GLY B 138
HIS B 172
ILE B 136
1.35A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS B 163
ILE B 136
GLY D   2
SER D   1
1.21A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY C   2
GLY A 138
HIS A 172
ILE A 136
1.34A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY C 146
GLY C 174
HIS C 163
ILE C 136
GLY C 149
1.78A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR B 118
LEU B 141
HIS B 172
GLU B 166
1.65A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY A   2
GLY C 138
HIS C 172
ILE C 136
1.37A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR C 118
LEU C 141
GLU C 166
HIS C 172
1.78A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
GLY B   2
GLY D 138
HIS D 172
ILE D 136
1.37A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR D 118
LEU D 141
GLU D 166
HIS D 172
1.72A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY D 146
GLY D 174
HIS D 163
ILE D 136
GLY D 149
1.74A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.73A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.77A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
GLU A 166
1.58A21.59

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.27A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 375
1.43A12.35

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 8
GLY A 559
GLY A 503
ILE A 562
SER A 564
THR A 565
1.50A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.26A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 8
GLY A 503
GLY A 559
GLY A 683
SER A 564
SER A 561
1.58A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 678
GLY A 679
ILE A 632
SER A 664
1.36A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
GLY A 559
GLY A 683
SER A 501
THR A 565
1.32A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 732
LEU A 240
ASN A 705
HIS A 133
1.45A12.35

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 539
SER A 681
1.53A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 539
SER A 681
1.55A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.35A
SO4  A 201 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.35A
SO4  B 201 ( 4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
ASN A  37
HIS A  45
HIS A  94
ALA A  60
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
ASN B  37
HIS B  45
HIS B  94
ALA B  60
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
GLY B  51
GLY B  48
ILE B 131
GLY B  46
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 8
GLY B 247
GLY B 248
HIS B 235
ILE B 236
THR B 341
1.30A24.87
CIT  B 408 (-3.1A)
CIT  B 408 (-3.5A)
CIT  B 408 (-4.2A)
None
CIT  B 408 (-3.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w02 NSP3
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.32A22.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
GLY C 446
GLY C 447
GLY C 496
SER C 443
1.39A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
GLY C 446
GLY C 447
GLY C 496
SER C 443
1.45A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  97
GLY C 431
SER C 383
SER H  96
1.70A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  97
GLY C 381
SER C 383
SER H  96
1.59A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY C 381
GLY C 431
ILE C 434
GLY H  97
1.53A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  97
GLY H  95
GLY H  94
SER C 383
THR C 385
1.74A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
GLY C 502
GLY C 504
GLY C 404
ILE C 402
1.45A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY C 381
GLY C 431
GLY H  97
SER C 383
0.97A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  97
GLY H  95
SER C 383
THR C 385
1.59A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  94
GLY H  95
GLY H  97
THR C 385
1.02A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
GLY C 502
GLY C 504
GLY C 404
ILE C 402
1.43A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w4h NSP16
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.43A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w4h NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.57A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
GLY A6871
SER A6903
THR A6908
1.21A
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A7079
GLY A7076
SER A7074
1.56A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4380
GLY B4374
ILE B4308
GLY B4305
1.26A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
THR A7055
1.66A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
GLY B4347
SER B4325
1.59A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
HIS A6867
SER A6903
THR A6880
1.67A20.28
SAM  A7104 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
SER A6964
1.52A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
THR B4309
1.54A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
ILE B4308
SER B4325
THR B4364
1.52A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A7076
GLY A6962
ILE A7079
THR A7055
1.53A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A6951
GLY A7006
SER A6964
1.50A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
THR A6880
1.38A
SAM  A7104 (-4.4A)
SAM  A7104 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A7011
ILE A7065
GLY A6962
SER A7074
1.55A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A6926
GLY A7006
SER A6964
1.55A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
GLY B4347
SER B4325
1.55A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7080
GLY A7076
SER A7074
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
GLY B4347
THR A6880
1.39A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY B4323
GLY B4322
SER A6903
THR A6880
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6875
ILE A6910
GLY A6871
SER A6872
1.49A20.28
None
None
SAM  A7104 (-4.4A)
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
ILE A6866
1.34A
SAM  A7104 (-4.4A)
SAM  A7104 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
SER A6964
1.51A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
ILE A6910
SER A6903
THR A6908
0.98A
SAM  A7104 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.37A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
1.52A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.29A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6962
ILE A7080
GLY A7076
SER A7074
1.50A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
ILE A7069
SER A7074
1.60A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
THR A6880
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
GLY B4303
GLY B4305
ILE B4308
THR B4309
1.66A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
HIS A6972
GLU A6971
1.56A22.66
None
None
KCX  A6935 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6962
GLY A6963
SER A7074
THR A6856
1.63A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
GLU A6971
HIS A6972
1.56A22.66
None
None
None
KCX  A6935 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
GLU A 166
1.59A
None
None
X77  A 401 ( 4.6A)
X77  A 401 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.79A
None
None
X77  A 401 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B 130
GLY B 133
ILE B 106
SER B 128
1.71A21.01
MES  B 201 ( 3.4A)
None
None
MES  B 201 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  79
GLY A  78
GLY A  97
SER A 111
1.63A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  46
GLY B  51
ILE B  23
GLY B  48
1.46A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A 130
GLY A 133
ILE A 106
SER A 139
1.56A21.01
AMP  A 201 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  79
GLY A  78
GLY A  97
SER A  80
1.48A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  51
GLY B  48
ILE B 131
GLY B  46
1.38A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  46
GLY A  51
HIS A  45
GLY A  48
1.63A21.01
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  46
GLY B  51
HIS B  45
GLY B  48
1.60A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  47
GLY B  48
ILE B  23
GLY B  51
1.64A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  79
GLY A  78
GLY A  97
SER A 111
1.64A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  79
GLY B  78
GLY B  97
SER B  80
1.47A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY B  79
GLY B  78
GLY B  97
SER B  80
1.45A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  47
GLY A  48
ILE A  23
GLY A  51
1.54A21.01
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A 130
GLY A 133
ILE A 106
SER A 139
1.58A21.01
AMP  A 201 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A 130
GLY A 133
ILE A 106
SER A 128
1.64A21.01
AMP  A 201 ( 3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  79
GLY A  78
GLY A  97
SER A  80
1.45A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.32A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
GLY A  46
GLY A  51
ILE A  23
GLY A  48
1.37A21.01
None
None
AMP  A 201 ( 4.0A)
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.30A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A6926
GLY A7006
SER A6964
1.53A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
THR A6880
1.66A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
ILE A7069
SER A7074
1.54A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A7011
ILE A7065
GLY A6962
SER A7074
1.51A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C6828
LEU C6825
GLU C6971
HIS C6972
1.61A23.41
None
None
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
GLU A6971
HIS A6972
1.61A23.41
None
None
None
FMT  A7103 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.26A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
ILE B4308
SER B4325
THR B4364
1.55A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.26A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
THR A6880
1.41A20.42
SAM  A7102 ( 4.2A)
SAM  A7102 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
ILE A7080
GLY A7011
1.54A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7069
GLY C7076
SER C7074
1.44A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
HIS A6867
SER A6903
THR A6880
1.54A20.42
SAM  A7102 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
GLY C6962
ILE C7069
SER C7074
1.54A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7080
GLY C7076
SER C7074
1.77A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
GLY C6869
HIS C6867
ILE C6866
1.35A20.42
SAM  C7105 ( 4.2A)
SAM  C7105 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
1.54A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
ILE A6910
SER A6903
THR A6908
0.94A20.42
SAM  A7102 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
SER A6964
1.51A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
SER A6964
1.52A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6875
ILE C6910
GLY C6871
SER C6872
1.41A20.42
None
None
SAM  C7105 ( 4.2A)
SAM  C7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6962
GLY A6963
SER A7074
THR A6856
1.61A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.44A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A7079
GLY A7076
SER A7074
1.57A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
GLY B4347
SER B4325
1.62A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6962
GLY A6963
ILE A6955
GLY A7011
1.52A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
ILE A6866
1.34A20.42
SAM  A7102 ( 4.2A)
SAM  A7102 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4303
GLY D4305
ILE D4308
THR D4309
1.67A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
HIS C6867
SER C6903
THR C6880
1.53A20.42
SAM  C7105 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
GLY C6962
GLY C7076
SER C6964
1.50A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6875
GLY C6871
SER C6903
THR C6880
1.69A20.42
None
SAM  C7105 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6869
GLY A6871
ILE A6910
SER A6896
1.70A20.42
SAM  A7102 ( 3.8A)
SAM  A7102 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
HIS A6972
GLU A6971
1.59A23.41
None
None
FMT  A7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
GLY D4347
SER D4325
1.59A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6962
ILE A7080
GLY A7076
SER A7074
1.54A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6962
ILE C7080
GLY C7076
SER C7074
1.53A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
ILE A6951
GLY A7006
SER A6964
1.47A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
GLY C6869
HIS C6867
SER C6903
1.58A20.42
SAM  C7105 ( 4.2A)
SAM  C7105 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
GLY C6871
SER C6903
THR C6908
1.15A20.42
SAM  C7105 ( 3.4A)
SAM  C7105 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
ILE A7065
GLY A7011
1.63A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A7076
GLY A6962
ILE A7079
THR A7055
1.51A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.44A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
GLY A7076
THR A7055
1.67A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
ILE C6910
SER C6903
THR C6908
0.93A20.42
SAM  C7105 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 8
GLY D4347
GLY D4323
GLY D4322
SER C6903
THR C6880
1.63A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7011
1.28A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C7076
GLY C6962
ILE C7079
THR C7055
1.46A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4303
GLY B4305
ILE B4308
THR B4309
1.68A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6875
ILE A6910
GLY A6871
SER A6872
1.43A20.42
None
None
SAM  A7102 ( 4.2A)
SAM  A7102 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.56A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY B4323
GLY B4322
SER A6903
THR A6880
1.34A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
GLY D4347
SER C6903
1.45A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.25A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4380
GLY D4374
ILE D4308
GLY D4305
1.23A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
ILE D4308
SER D4325
THR D4364
1.53A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7080
GLY A7076
SER A7074
1.79A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.25A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4380
GLY B4374
ILE B4308
GLY B4305
1.24A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
GLY C6962
GLY C7076
THR C7055
1.63A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
ILE C7079
GLY C7076
SER C7074
1.56A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY D4323
GLY D4322
SER C6903
THR C6880
1.33A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
ILE C6926
GLY C7006
SER C6964
1.54A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6962
GLY C6963
SER C7074
THR C6856
1.61A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
THR D4309
1.55A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
GLY D4347
SER D4325
1.62A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C7011
ILE C7065
GLY C6962
SER C7074
1.50A20.42
 NA  C7103 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
GLY A6871
SER A6903
THR A6908
1.13A20.42
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6962
ILE C7069
GLY C7076
SER C7074
1.44A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
THR B4309
1.54A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
GLY C6962
GLY C7076
SER C6964
1.51A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
GLY B4347
SER B4325
1.66A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY D4347
GLY D4323
GLY D4322
SER C6903
1.51A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
SER A6903
1.60A20.42
SAM  A7102 ( 4.2A)
SAM  A7102 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6875
GLY A6871
SER A6903
THR A6880
1.68A20.42
None
SAM  A7102 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY A6963
GLY A6962
SER A6964
THR A6856
1.69A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
GLY C6869
HIS C6867
THR C6880
1.40A20.42
SAM  C7105 ( 4.2A)
SAM  C7105 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP10
(SARS-CoV-2)		5 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
THR D4309
1.55A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
GLY C6963
GLY C6962
SER C6964
THR C6856
1.69A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR B  72
LEU B 150
ASN B  13
ALA B 135
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR C  83
LEU C  87
ASN C  13
ALA C 145
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR B  83
LEU B  87
GLU B 143
ALA B 145
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR B  83
LEU B  87
ASN B  13
ALA B 145
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A  72
LEU A 150
ASN A  13
ALA A 135
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR C  72
LEU C 150
ASN C  13
ALA C 135
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
TYR A  68
LEU A  43
ASN A 115
ALA A  39
1.80A
None
None
None
MES  A 201 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
ASN A  37
HIS A  45
HIS A  94
ALA A  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wen NSP3
(SARS-CoV-2)		4 / 8
GLY A  48
GLY A  47
GLY A  46
HIS A  45
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
LEU A 279
ASN A 241
HIS A 298
HIS A 249
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
ASN A 241
HIS A 249
HIS A 298
ALA A 264
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY B 316
GLY A 287
ILE A 357
GLY A 284
SER B 318
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY D 316
GLY C 287
ILE C 357
GLY C 284
SER D 318
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY C 316
GLY D 287
ILE D 357
GLY D 284
SER C 318
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY E 316
GLY F 287
ILE F 357
GLY F 284
SER E 318
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY F 316
GLY E 287
ILE E 357
GLY E 284
SER F 318
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
GLY A 316
GLY B 287
ILE B 357
GLY B 284
SER A 318
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
HIS A6972
GLU A6971
1.57A
None
None
FMT  A7103 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6879
GLY C6871
SER C6903
THR C6908
1.14A
SAH  C7102 (-3.5A)
SAH  C7102 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7069
GLY C7076
SER C7074
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
GLU A6971
HIS A6972
1.56A
None
None
None
FMT  A7103 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 8
GLY D4347
GLY D4323
GLY D4322
SER C6903
THR C6880
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR C6828
LEU C6825
GLU C6971
HIS C6972
1.61A
None
None
None
FMT  C7104 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY C6871
ILE C6910
SER C6903
THR C6908
0.96A
SAH  C7102 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
ILE A6910
SER A6903
THR A6908
0.95A
SAH  A7102 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
THR A6880
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY B4380
GLY B4374
ILE B4308
GLY B4305
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
ILE A6866
1.37A
SAH  A7102 (-4.4A)
SAH  A7102 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		5 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
THR D4309
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7080
GLY C7076
SER C7074
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wjt NSP10
(SARS-CoV-2)		4 / 8
GLY D4380
GLY D4374
ILE D4308
GLY D4305
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
GLY A6871
SER A6903
THR A6908
1.12A
SAH  A7102 (-3.5A)
SAH  A7102 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY B4323
GLY B4322
SER A6903
THR A6880
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY D4323
GLY D4322
SER C6903
THR C6880
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY A 116
GLY A 147
ILE A 146
GLY A 114
0.90A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY A 170
HIS B 145
ILE B 146
SER B  79
1.26A
None
ZN  B 202 (-3.3A)
MES  B 201 ( 4.6A)
ZN  B 202 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY B 116
GLY B 147
ILE B 146
GLY B 114
0.94A
None
None
MES  B 201 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY C 116
GLY C 147
ILE C 146
GLY C 114
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
GLY D 116
GLY D 147
ILE D 146
GLY D 114
0.93A
None
None
MES  D 201 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
LEU B  56
HIS B  59
HIS C 145
ALA B  55
1.66A
None
ZN  C 201 (-3.3A)
ZN  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
LEU D  56
HIS D  59
HIS A 145
ALA D  55
1.68A
None
ZN  A 201 (-4.1A)
ZN  A 201 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7069
GLY C7076
SER C7074
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
GLY D4380
GLY D4374
ILE D4308
GLY D4305
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6879
GLY C6871
SER C6903
THR C6908
1.14A
SFG  C7103 ( 3.5A)
SFG  C7103 ( 4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
ILE C6910
SER C6903
THR C6908
0.93A
SFG  C7103 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY C6871
GLY C6869
HIS C6867
ILE C6866
1.36A
SFG  C7103 ( 4.1A)
SFG  C7103 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
HIS A6972
GLU A6971
1.57A
None
None
FMT  A7105 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6879
GLY A6871
SER A6903
THR A6908
1.12A
SFG  A7103 ( 3.5A)
SFG  A7103 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		5 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
THR D4309
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 8
GLY D4347
GLY D4323
GLY D4322
SER C6903
THR C6880
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
THR A6880
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY D4323
GLY D4322
SER C6903
THR C6880
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
GLY B4380
GLY B4374
ILE B4308
GLY B4305
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
GLY B4323
GLY B4322
SER A6903
THR A6880
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 8
GLY C6963
GLY C6962
ILE C7080
GLY C7076
SER C7074
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
GLU A6971
HIS A6972
1.54A
None
None
None
FMT  A7105 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
GLY D4322
GLY D4323
ILE D4308
SER D4320
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR C6828
LEU C6825
GLU C6971
HIS C6972
1.60A
None
None
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7080
GLY A7076
SER A7074
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
ILE A6866
1.36A
SFG  A7103 ( 4.2A)
SFG  A7103 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
GLY A6871
ILE A6910
SER A6903
THR A6908
0.95A
SFG  A7103 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wkq NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 8
GLY B 247
GLY B 248
HIS B 235
ILE B 236
THR B 341
1.35A
None
U5P  B 401 ( 4.4A)
None
None
U5P  B 401 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLY B 247
GLY B 239
HIS B 235
ILE B 236
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLY B 247
GLY B 248
SER B 289
SER B 288
1.37A
None
U5P  B 401 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLY B 247
GLY B 239
HIS B 235
ILE B 236
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLY A 247
GLY A 239
HIS A 235
ILE A 236
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 8
GLY A 247
GLY A 248
HIS A 235
ILE A 236
THR A 341
1.35A
None
U5P  A 401 ( 4.5A)
None
None
U5P  A 401 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLY A 247
GLY A 248
SER A 289
SER A 288
1.35A
None
U5P  A 401 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 8
GLY A 247
GLY A 239
HIS A 235
ILE A 236
THR A 341
1.41A
None
None
None
None
U5P  A 401 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 172
ILE A 136
GLY A 146
SER A 144
1.26A
None
None
None
U5G  A 401 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
HIS A 163
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
GLU A 166
1.71A
None
None
None
U5G  A 401 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN B  37
HIS B  45
HIS B  94
ALA B  60
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN D  37
HIS D  45
HIS D  94
ALA D  60
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN A  37
HIS A  45
HIS A  94
ALA A  60
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN C  37
HIS C  45
HIS C  94
ALA C  60
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU C  75
ASN C  37
HIS C  94
HIS C  45
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU D  75
ASN D  37
HIS D  94
HIS D  45
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 NSP10
(SARS-CoV-2)		4 / 8
GLY B4380
GLY B4374
ILE B4308
GLY B4305
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6828
LEU A6825
GLU A6971
HIS A6972
1.63A
GTA  A7102 (-3.4A)
GTA  A7102 (-3.8A)
GTA  A7102 (-4.1A)
GTA  A7102 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 8
GLY B4347
GLY B4323
GLY B4322
SER A6903
THR A6880
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 NSP10
(SARS-CoV-2)		4 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 NSP10
(SARS-CoV-2)		5 / 8
GLY B4322
GLY B4323
ILE B4308
SER B4320
THR B4309
1.58A
None
None
None
None
SO4  B4404 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
GLY A6963
GLY A6962
ILE A7069
GLY A7076
SER A7074
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
GLY A6869
HIS A6867
ILE A6866
1.35A
SAH  A7101 (-4.3A)
SAH  A7101 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6879
GLY A6871
SER A6903
THR A6908
1.15A
SAH  A7101 (-3.5A)
SAH  A7101 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
GLY A6871
ILE A6910
SER A6903
THR A6908
0.94A
SAH  A7101 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
GLY B4323
GLY B4322
SER A6903
THR A6880
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
TYR A  83
LEU A  87
ASN A  13
ALA A 145
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
TYR A  72
LEU A 150
ASN A  13
ALA A 135
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 170
GLY A 138
ILE A 136
THR A 135
1.46A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
ILE A 136
SER A 147
1.41A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
1.48A17.42
None
None
DMS  A 405 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A17.42
None
None
DMS  A 405 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.75A23.72
None
None
DMS  A 405 (-3.4A)
DMS  A 405 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 215
ILE A 213
GLY A   2
SER A   1
1.62A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 138
HIS A 163
ILE A 136
GLY A 170
1.35A17.42
None
DMS  A 405 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 174
HIS A 163
ILE A 136
SER A 147
1.54A17.42
None
DMS  A 405 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 120
GLY A 146
SER A 144
SER A 147
1.36A17.42
None
None
DMS  A 405 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 172
ILE A 136
GLY A 146
SER A 144
1.25A17.42
DMS  A 405 ( 4.8A)
None
None
DMS  A 405 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A  29
GLY A 143
SER A 144
1.35A17.42
None
None
None
DMS  A 405 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 174
ILE A 136
SER A 147
1.45A17.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 138
ILE A 136
SER A 147
SER A 144
1.72A17.42
None
None
None
DMS  A 405 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
GLY A 146
GLY A 120
GLY A 143
SER A 144
1.44A17.42
None
None
None
DMS  A 405 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
LYS B  79
LEU C  41
GLU C  47
ALA C  42
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
LYS D  79
LEU A  41
GLU A  47
ALA A  42
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLY A 502
GLY A 504
GLY A 404
ILE A 402
1.33A
None
DMS  A 903 ( 4.0A)
DMS  A 903 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY B  99
GLY B  98
ILE B  50
GLY B 101
SER A 383
1.74A
None
None
None
None
DMS  A 905 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY E 381
GLY E 431
GLY H 101
SER E 383
1.18A
None
None
None
DMS  L1601 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY B  98
ILE B 102
SER A 383
THR B 104
1.20A
None
None
DMS  A 905 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY B  98
GLY B  99
GLY B 101
THR A 385
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
GLY H 101
SER E 383
SER H 100
1.75A
None
None
None
DMS  L1601 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  98
GLY H  99
GLY H 101
THR E 385
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
ILE H  50
GLY H 101
SER E 383
1.76A
None
None
None
None
DMS  L1601 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY A 381
GLY A 431
GLY B 101
SER A 383
1.22A
None
None
None
DMS  A 905 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY B  99
GLY B  98
GLY B 101
SER A 383
SER B 100
1.75A
None
None
None
DMS  A 905 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  98
GLY H  99
GLY H 101
THR E 385
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY E 381
GLY E 431
GLY H 101
SER E 383
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY E 381
GLY E 431
GLY H 101
SER H 100
SER E 383
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  98
ILE H 102
SER E 383
THR H 104
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
GLY H 101
SER E 383
SER H 100
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLY E 502
GLY E 504
GLY E 404
ILE E 402
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
ILE H  50
GLY H 101
SER E 383
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A
None
None
P6N  A 502 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.71A
None
None
P6N  A 502 (-2.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
GLY H 101
SER E 383
SER H 100
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY A 381
GLY A 431
GLY B 101
SER A 383
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY B  99
GLY B  98
GLY B 101
SER A 383
SER B 100
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY B  99
GLY B  98
ILE B  50
GLY B 101
SER A 383
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 8
GLY H  99
GLY H  98
ILE H  50
GLY H 101
SER E 383
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY E 381
GLY E 431
GLY H 101
SER E 383
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY H  98
GLY H  99
GLY H 101
THR E 385
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLY B  98
GLY B  99
GLY B 101
THR A 385
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.72A
None
None
DMS  A 403 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU C  75
ASN C  37
HIS C  94
HIS C  45
1.31A
EPE  C 202 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  46
GLY E 133
ILE E 131
GLY B  51
1.26A
None
None
EPE  E 202 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
GLY B  51
GLY B  46
GLY E 133
ILE E 131
GLY B  48
1.61A
None
None
None
EPE  E 202 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU D  75
ASN D  37
HIS D  94
HIS D  45
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU E  75
ASN E  37
HIS E  94
HIS E  45
1.33A
EPE  E 203 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  48
GLY B  47
GLY E 133
ILE E 131
1.04A
None
None
None
EPE  E 202 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN D  37
HIS D  45
HIS D  94
ALA D  60
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  51
GLY B  48
ILE B 131
GLY E 133
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  48
GLY B  47
GLY E 133
ILE E 131
1.02A
APR  B 201 (-3.5A)
APR  B 201 (-3.6A)
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN E  37
HIS E  45
HIS E  94
ALA E  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN B  37
HIS B  45
HIS B  94
ALA B  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU D  75
ASN D  37
HIS D  94
HIS D  45
1.33A
EDO  D 202 (-4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU C  75
ASN C  37
HIS C  94
HIS C  45
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN C  37
HIS C  45
HIS C  94
ALA C  60
1.34A
None
None
None
EDO  D 204 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU E  75
ASN E  37
HIS E  94
HIS E  45
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
GLY B  51
GLY B  46
GLY E 133
ILE E 131
GLY B  48
1.64A
None
EDO  B 202 (-3.9A)
None
APR  E 201 (-3.4A)
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN D  37
HIS D  45
HIS D  94
ALA D  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A  37
HIS A  45
HIS A  94
ALA A  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLY B  51
GLY B  48
ILE B 131
GLY E 133
1.06A
None
APR  B 201 (-3.5A)
APR  B 201 (-3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU B  75
ASN B  37
HIS B  94
HIS B  45
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU A  75
ASN A  37
HIS A  94
HIS A  45
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
LEU C  75
ASN C  37
HIS C  94
HIS C  45
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A  37
HIS A  45
HIS A  94
ALA A  60
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN B  37
HIS B  45
HIS B  94
ALA B  60
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN C  37
HIS C  45
HIS C  94
ALA C  60
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
HIS A 172
GLU A 166
1.65A
None
None
PJE  C   5 (-4.4A)
PJE  C   5 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 118
LEU A 141
GLU A 166
HIS A 172
1.80A
None
None
PJE  C   5 (-3.7A)
PJE  C   5 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A
None
None
PJE  C   5 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.25A
None
ZN  A1002 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 562
THR A 565
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 375
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 539
SER A 681
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 559
GLY A 503
ILE A 562
SER A 564
THR A 565
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 376
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLY A 559
GLY A 683
SER A 501
THR A 565
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.25A
None
ZN  A1002 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 539
SER A 681
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 732
LEU A 240
ASN A 705
HIS A 133
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 748
LEU A 707
ASN A 767
ALA A 706
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 503
GLY A 559
GLY A 683
SER A 564
SER A 561
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLY A 503
GLY A 559
GLY A 683
SER A 501
THR A 565
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 884
LEU A 883
ASN A 416
ALA A 423
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.74A
None
None
DMS  A 402 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.28A
None
ZN  A1002 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
GLY A 559
GLY A 683
SER A 501
THR A 565
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 286
LEU A 251
GLU A 180
ALA A 250
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 8
GLY A 683
GLY A 559
GLY A 503
ILE A 562
THR A 565
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 8
GLY A 559
GLY A 503
ILE A 562
SER A 564
THR A 565
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 732
LEU A 240
ASN A 705
HIS A 133
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 375
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 884
LEU A 883
ASN A 416
ALA A 423
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
GLY A 485
GLY A 486
ILE A 488
SER A 578
1.34A
None
ZN  A1002 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
GLY A 683
GLY A 559
ILE A 539
SER A 681
1.26A
 U  T  10 ( 3.1A)
U  T  10 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 375
1.18A
None
None
U  T   8 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 515
LEU A 372
ASN A 507
ALA A 376
1.63A
None
None
U  T   8 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 8
GLY A 228
GLY A 200
ILE A 223
GLY A 230
SER A 229
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 884
LEU A 883
ASN A 416
ALA A 423
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 732
LEU A 240
ASN A 705
HIS A 133
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
GLY A 228
GLY A 200
ILE A 223
SER A 229
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 8
GLY A 559
GLY A 503
ILE A 562
SER A 564
THR A 565
1.60A
 U  T  10 ( 3.5A)
None
None
None
None