Ligand ID: EU7


Drugbank ID:
DB00478
(Rimantadine)


Indication:
For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.

Get human targets for EU7 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'EU7' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.58A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.75A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 6
SER D 937
ALA D 944
SER D 940
ALA F 942
1.38A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 9
SER B 937
ALA B 944
SER B 940
ALA A 942
VAL A1189
1.67A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.74A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.75A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER B 139
SER D 301
ALA B 116
SER B 123
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 301
ALA A 116
SER A 123
SER A 139
1.72A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 301
ALA B 116
SER B 123
SER B 139
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 121
ALA D 116
SER D 123
SER D 147
1.60A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 121
ALA C 116
SER C 123
SER C 147
1.72A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 147
SER C 121
ALA C 116
SER C 123
1.73A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 9
ALA B 255
VAL B 261
ALA B 260
SER B 254
VAL B 247
1.77A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 147
SER D 121
ALA D 116
SER D 123
1.60A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.79A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER A 139
SER C 301
ALA A 116
SER A 123
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.77A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 9
SER A 397
VAL A 405
ALA A 400
SER A 672
VAL B 131
1.59A2.46

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.73A2.46

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER A 730
VAL A1060
ALA A1056
SER A1055
VAL A 729
1.53A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.53A9.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.54A
None
NHE  A 202 (-4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER C 730
VAL C1060
ALA C1056
SER C1055
VAL C 729
1.56A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
SER B 937
SER B 940
ALA B 944
SER B 943
1.32A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER C 691
ALA C 672
SER C 673
ALA C 609
GLY C 652
1.66A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w4h NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.49A6.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.75A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.75A9.38
None
None
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4323
1.79A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4322
1.76A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.37A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.50A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4323
1.61A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA A6877
SER A6903
GLY A6871
1.65A9.38
None
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
SER A6903
GLY B4322
1.73A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.52A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.54A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4323
1.60A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4322
1.48A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA A6877
SER A6903
GLY A6871
1.66A9.38
None
None
None
None
SAM  A7102 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4322
1.77A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA C6877
SER C6903
GLY C6871
1.69A9.38
None
None
None
None
SAM  C7105 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.31A9.38
FMT  C7111 ( 4.8A)
None
None
FMT  C7111 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.36A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4323
1.63A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.51A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.72A9.38
None
None
None
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.73A9.38
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.50A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
ALA C6870
SER C6896
ALA C6877
GLY C6871
SER C6903
1.72A9.38
None
None
None
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.73A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.49A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA D4324
VAL C6876
GLY D4322
1.78A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.69A9.38
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wcf NSP3
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wen NSP3
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		5 / 9
ALA A 231
VAL A 238
ALA A 293
VAL A 240
GLY A 289
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		5 / 9
GLY A 334
ALA A 338
SER A 332
GLY A 337
SER A 343
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA E 308
ALA F 313
SER F 312
GLY F 316
SER F 310
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA C 308
ALA D 313
SER D 312
GLY D 316
SER D 310
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER F 310
ALA E 264
ALA F 311
SER F 312
1.65A
None
None
CL  E 401 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 273
ALA A 313
GLY A 316
ALA A 311
SER A 310
1.80A
None
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 264
ALA A 313
GLY A 316
ALA A 311
SER A 310
1.57A
None
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 308
ALA C 313
SER C 312
GLY C 316
SER C 310
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER E 310
ALA F 264
ALA E 311
SER E 312
1.61A
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 264
GLY A 295
ALA B 313
GLY B 316
SER B 310
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA C 264
GLY C 295
ALA D 313
GLY D 316
SER D 310
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 264
GLY F 295
ALA E 313
GLY E 316
SER E 310
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA E 264
GLY E 295
ALA F 313
GLY F 316
SER F 310
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 305
ALA B 313
SER B 312
GLY B 316
SER B 310
1.51A
 CL  A 401 ( 4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER D 310
ALA C 264
ALA D 311
SER D 312
1.61A
None
None
CL  C 401 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 264
ALA E 313
GLY E 316
ALA E 311
SER E 310
1.56A
None
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 273
ALA E 313
GLY E 316
ALA E 311
SER E 310
1.78A
None
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 273
ALA B 313
GLY B 316
ALA B 311
SER B 310
1.77A
None
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 264
ALA B 313
GLY B 316
ALA B 311
SER B 310
1.56A
None
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 308
ALA A 313
SER A 312
GLY A 316
SER A 310
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 305
ALA A 313
SER A 312
GLY A 316
SER A 310
1.51A
 CL  B 401 ( 4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER A 310
ALA B 264
ALA A 311
SER A 312
1.62A
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA E 264
ALA F 313
GLY F 316
ALA F 311
SER F 310
1.55A
None
None
None
CL  E 401 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 273
ALA C 313
GLY C 316
ALA C 311
SER C 310
1.78A
None
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA C 305
ALA D 313
SER D 312
GLY D 316
SER D 310
1.51A
 CL  C 401 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 305
ALA E 313
SER E 312
GLY E 316
SER E 310
1.51A
 CL  F 401 ( 4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 264
GLY B 295
ALA A 313
GLY A 316
SER A 310
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER B 310
ALA A 264
ALA B 311
SER B 312
1.61A
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER C 310
ALA D 264
ALA C 311
SER C 312
1.65A
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 264
GLY D 295
ALA C 313
GLY C 316
SER C 310
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA C 264
ALA D 313
GLY D 316
ALA D 311
SER D 310
1.57A
None
None
None
CL  C 401 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 308
ALA B 313
SER B 312
GLY B 316
SER B 310
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 308
ALA E 313
SER E 312
GLY E 316
SER E 310
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 264
ALA C 313
GLY C 316
ALA C 311
SER C 310
1.57A
None
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4322
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.71A
None
None
None
SAH  A7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER A6872
ALA B4324
SER B4325
ALA A6877
1.77A
SAH  A7102 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER C6872
ALA D4324
SER D4325
ALA C6877
1.72A
SAH  C7102 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA C6870
SER C6896
ALA C6877
GLY C6871
SER C6903
1.71A
None
None
None
SAH  C7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA A6877
SER A6903
GLY A6871
1.66A
None
None
None
None
SAH  A7102 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA D4324
VAL C6876
GLY D4322
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4322
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4323
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA C6877
SER C6903
GLY C6871
1.68A
None
None
None
None
SAH  C7102 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4323
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA D4324
VAL C6876
GLY D4322
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4323
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA A6877
SER A6903
GLY A6871
1.66A
None
None
None
None
SFG  A7103 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4322
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.30A
FMT  C7111 ( 4.9A)
None
None
FMT  C7111 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.74A
None
FMT  C7111 ( 3.5A)
FMT  C7111 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.68A
None
FMT  C7111 ( 3.5A)
FMT  C7111 ( 3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.72A
None
None
None
SFG  A7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4323
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
ALA D4324
SER C6903
GLY D4347
GLY D4322
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ALA C6870
SER C6896
ALA C6877
GLY C6871
SER C6903
1.75A
None
None
None
SFG  C7103 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ALA C6905
VAL C6902
ALA C6877
SER C6903
GLY C6871
1.69A
None
None
None
None
SFG  C7103 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
SER A 267
VAL A 261
ALA A 260
SER A 254
GLY A 258
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA D  27
VAL D  34
ALA D  89
VAL D  36
GLY D  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER D 139
ALA D  38
ALA D 129
SER D 128
1.41A
None
APR  D 201 (-3.2A)
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
SER B  80
ALA B 112
GLY B  78
ALA B  39
GLY B  97
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA C  27
VAL C  34
ALA C  89
VAL C  36
GLY C  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
SER A  80
ALA A 112
GLY A  78
ALA A  39
GLY A  97
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER D 128
SER D 139
ALA D 124
ALA D  38
1.37A
APR  D 201 (-4.3A)
None
None
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER A6872
ALA B4324
SER B4325
ALA A6877
1.79A
SO4  A7109 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
SER A6903
GLY B4322
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.71A
None
None
None
SAH  A7101 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA A6877
SER A6903
GLY A6871
1.69A
None
None
None
None
SAH  A7101 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4323
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
ALA B4324
SER A6903
GLY B4347
GLY B4322
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4322
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6905
VAL A6902
ALA B4324
VAL A6876
GLY B4323
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.60A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
SER A 121
ALA A 116
SER A 123
GLY A 124
SER A 147
1.79A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.79A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.59A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA E  27
VAL E  34
ALA E  89
VAL E  36
GLY E  85
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   7
SER C   5
SER E 166
ALA B  70
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA D  27
VAL D  34
ALA D  89
VAL D  36
GLY D  85
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA C  27
VAL C  34
ALA C  89
VAL C  36
GLY C  85
1.56A
None
EDO  C 207 (-4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA D  27
VAL D  34
ALA D  89
VAL D  36
GLY D  85
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA C  27
VAL C  34
ALA C  89
VAL C  36
GLY C  85
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA E  27
VAL E  34
ALA E  89
VAL E  36
GLY E  85
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   7
SER C   5
SER E 166
ALA B  70
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA C  27
VAL C  34
ALA C  89
VAL C  36
GLY C  85
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA B  27
VAL B  34
ALA B  89
VAL B  36
GLY B  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 9
ALA A  27
VAL A  34
ALA A  89
VAL A  36
GLY A  85
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		5 / 9
ALA A 558
SER A 681
GLY A 683
GLY A 559
SER A 561
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 9
ALA A 255
VAL A 261
ALA A 260
SER A 254
VAL A 247
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
SER C  54
ALA D 102
ALA D 152
SER D 151
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
SER A 835
ALA A 866
VAL A 880
VAL A 435
GLY A 841
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 9
SER A 397
VAL A 405
ALA A 400
SER A 672
VAL B 131
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.64A
None