Ligand ID: DZP


Drugbank ID:
DB00829
(Diazepam)


Indication:
Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Get human targets for DZP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'DZP' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.73A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6lvn SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE D  16
ASN D  20
LEU B  19
VAL B  22
GLU D  15
1.63A4.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6lvn SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE D  16
ASN D  20
LEU B  19
GLU D  15
ARG D  18
1.69A4.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE D1172
LEU F 966
LEU F 962
VAL E 963
LEU E 959
1.44A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.72A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.72A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE B 281
LEU B 250
LEU B 205
VAL B 204
LEU B 268
1.74A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.74A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE C 281
LEU C 250
LEU C 205
VAL C 204
LEU C 268
1.78A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D 281
LEU D 250
LEU D 205
VAL D 204
LEU D 268
1.75A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.70A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ASN D  76
PHE D  54
TYR D  88
SER D  52
TYR D 112
1.57A15.37
18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A  95
LEU B  65
TYR B  88
LEU B  57
LEU B 162
1.45A12.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 636
VAL A 637
CYH A 697
GLU A 474
ARG A 305
1.76A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 782
VAL A 700
LEU A 749
ARG A 750
1.79A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 187
LEU A 245
GLU A 254
LEU A 251
ARG A 183
1.54A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 241
ILE A 244
TYR A 286
LEU A 251
LEU A 316
1.77A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ILE A 632
LEU A 655
THR A 531
LEU A 638
PHE A 571
1.79A20.38
18.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		6 / 12
LEU A 470
LEU A 636
VAL A 637
CYH A 697
GLU A 474
ARG A 305
1.78A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 266
LEU A 282
TYR A 286
LEU A 251
VAL A 320
1.42A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU A 948
LEU A 945
VAL A1061
GLU A 819
LEU A 822
1.60A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU C 948
LEU C 945
VAL C1061
GLU C 819
LEU C 822
1.62A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 9
ASN B  75
PHE B  53
TYR B  87
SER B  51
TYR B 111
1.61A14.75
19.49
MES  A 203 (-3.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w4b NSP9
(SARS-CoV-2)		5 / 12
LEU B  45
ILE B  92
LEU B 107
VAL B 103
LEU B  89
1.65A11.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.71A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.72A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.70A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6848
PHE C7048
LEU C6887
VAL C6882
LEU C6883
1.69A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
LEU A  44
ILE A  91
LEU A 106
VAL A 102
LEU A  88
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C6848
PHE C7048
LEU C6887
VAL C6882
LEU C6883
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ASN D  75
PHE D  53
TYR D  87
SER D  51
TYR D 111
1.64A14.95
19.50
MES  D 201 (-3.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ASN A  75
PHE A  53
TYR A  87
SER A  51
TYR A 111
1.49A14.95
19.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ASN C  75
PHE C  53
TYR C  87
SER C  51
TYR C 111
1.57A14.95
19.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ASN B  75
PHE B  53
TYR B  87
SER B  51
TYR B 111
1.55A14.95
19.50
MES  B 201 (-3.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C6848
PHE C7048
LEU C6887
VAL C6882
LEU C6883
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
LEU B 215
ILE B 212
TYR B 238
GLU B 216
LEU B 217
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.74A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6848
PHE A7048
LEU A6887
VAL A6882
LEU A6883
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.74A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A  16
ILE A  14
ASN A  13
LEU A  80
GLU A  67
1.67A
None
None
None
None
CL  A 506 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.72A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.72A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.75A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.73A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 266
PHE A 321
LEU A 282
TYR A 286
LEU A 251
1.61A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 313
LEU A 245
GLU A 254
LEU A 251
ARG A 285
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 187
LEU A 245
GLU A 254
LEU A 251
ARG A 183
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 281
LEU A 250
LEU A 205
VAL A 204
LEU A 268
1.71A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
LEU A 470
LEU A 636
VAL A 637
CYH A 697
GLU A 474
ARG A 305
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 266
LEU A 282
TYR A 286
LEU A 251
VAL A 320
1.33A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
CYH A 645
LEU A 575
LEU A 638
CYH A 646
ARG A 640
1.76A20.61
 ZN  A1002 (-2.4A)
None
None
ZN  A1002 (-2.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 266
PHE A 321
LEU A 282
TYR A 286
LEU A 251
1.59A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 187
LEU A 245
GLU A 254
LEU A 251
ARG A 183
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 241
LEU A 245
GLU A 254
LEU A 251
ARG A 183
1.57A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 187
LEU A 245
GLU A 254
LEU A 251
ARG A 183
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
CYH A 306
LEU A 636
LEU A 655
CYH A 301
LEU A 351
1.52A20.61
 ZN  A1001 (-2.3A)
None
None
ZN  A1001 (-2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 266
PHE A 321
LEU A 282
TYR A 286
LEU A 251
1.61A20.61
None