Ligand ID: CFF


Drugbank ID:
DB00201
(Caffeine)


Indication:
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.

Get human targets for CFF in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'CFF' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.66A10.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A11.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A10.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.67A10.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 7
VAL E1164
LEU F 977
ASN F 978
ILE F 973
1.35A18.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.68A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A16.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A16.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.67A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A16.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.80A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.72A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.75A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.80A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.69A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.79A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.79A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.71A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.74A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.70A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.76A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 204
LEU A 271
MET A 276
ILE A 281
1.79A21.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.72A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.68A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.76A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.73A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.78A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.78A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.76A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.76A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.77A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE C 140
HIS C 164
GLY C 149
TYR C 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE D 140
HIS D 164
GLY D 149
TYR D 161
1.79A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.69A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.76A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE B 140
HIS B 164
GLY B 149
TYR B 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.68A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 132
PHE D  67
ILE D 131
TYR D 124
1.53A2.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.79A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
LEU A 316
LEU A 282
PHE A 317
PHE A 321
1.71A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6m71 NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.70A3.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL A 330
MET A 380
LEU B 103
ILE B 107
1.51A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.76A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6m71 NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.70A3.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6m71 NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.69A3.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL B  83
LEU A 372
MET A 566
ILE A 562
1.24A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m71 NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.70A3.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 7
MET B  94
LEU A 673
MET A 666
ILE A 539
1.73A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.31A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE A1115
PHE A1103
TRP A1102
ILE A1081
1.49A12.68
None
NAG  A1311 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.29A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ILE C1115
PHE C1103
TRP C1102
ILE C1081
1.51A12.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
ILE B 934
VAL B1065
GLU B 819
LEU B 878
ILE B 805
1.71A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.35A20.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 969
PHE C 970
GLY A 757
TYR A 756
1.29A20.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.30A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 969
PHE A 970
GLY B 757
TYR B 756
1.32A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.26A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL A 722
PHE A 927
LEU A1049
ILE A 720
1.48A13.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL B 276
PHE B 330
LEU B 298
ILE B 323
1.32A22.56
GOL  B 401 (-4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  47
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vxs NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN B 928
PHE B 927
ALA B 924
GLY B 799
1.39A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 928
PHE A 927
ALA A 924
GLY A 799
1.43A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL C 227
PHE C 168
LEU C 117
ILE C 231
1.45A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN B 928
PHE B 927
ALA B 924
GLY B 799
1.36A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 969
PHE C 970
GLY A 757
TYR A 756
1.34A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 928
PHE A 927
ALA A 924
GLY A 799
1.34A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN B 928
PHE B 927
ALA B 924
GLY B 799
1.38A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN B 928
PHE B 927
ALA B 924
GLY B 799
1.38A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
ILE B 231
VAL B 227
PHE B 168
GLU B 169
ILE B 119
1.48A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.38A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.41A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL A 227
PHE A 168
LEU A 117
ILE A 231
1.41A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.36A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.33A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.35A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.36A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 969
PHE A 970
GLY B 757
TYR B 756
1.36A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ILE D 131
PHE D  66
ILE D 130
TYR D 123
1.63A2.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w02 NSP3
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.03A12.51
None
None
APR  B 201 (-3.6A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
TYR C 505
GLY C 404
ASP C 405
GLU C 406
TYR C 449
1.74A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
LEU C 455
LEU C 452
ILE C 472
PHE C 490
1.61A19.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.50A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASP A6928
LEU A6848
PHE A7003
ILE A6925
1.56A
SAM  A7104 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.77A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.79A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.74A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.79A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  47
1.45A
None
None
MES  B 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.16A
None
None
MES  B 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.78A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.77A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.78A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.79A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
LEU D4345
ASP D4344
ILE D4352
PHE D4363
1.79A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.77A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.78A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6924
LEU C6959
ILE C7005
PHE C6985
1.77A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.76A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.76A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.78A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASP C6928
LEU C6848
PHE C7003
ILE C6925
1.55A20.12
SAM  C7105 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6848
PHE C6991
ILE C6969
PHE C7003
1.51A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.76A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.77A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.78A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.79A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A7005
PHE A6985
1.80A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.48A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ASP A6928
LEU A6848
PHE A7003
ILE A6925
1.55A20.12
SAM  A7102 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
PHE A  40
LEU A  94
ASN A  95
ILE A  91
1.62A17.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
VAL A   7
MET A 101
LEU A  42
ASN A  98
1.61A17.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
VAL A 102
LEU A  94
ASN A  95
ILE A  91
1.77A17.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 6
ASP A  26
LEU A  44
ILE A  65
PHE A  56
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.43A
None
None
MES  A 201 ( 3.0A)
MES  A 202 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wcf NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.18A
None
None
MES  A 201 ( 3.0A)
MES  A 202 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  48
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  48
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wen NSP3
(SARS-CoV-2)		4 / 6
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 244
PHE A 336
ALA A 254
GLY A 251
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 244
PHE A 336
ALA A 254
GLY A 251
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 258
HIS A 298
ALA A 254
GLY A 251
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 258
HIS A 298
ALA A 254
GLY A 250
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 244
PHE A 336
ALA A 254
GLY A 251
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wey NSP3
(SARS-CoV-2)		4 / 6
ASN A 244
PHE A 336
ALA A 254
GLY A 251
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6wiq NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.73A2.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6wiq NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.72A2.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 7
VAL A  66
PHE B  92
LEU A  56
ILE B 107
1.74A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wiq NSP8
(SARS-CoV-2)		4 / 7
VAL B 130
PHE B 147
ASN B 105
ILE B 120
1.59A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6wiq NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.73A2.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6wiq NSP8
(SARS-CoV-2)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.73A2.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 7
VAL A  66
PHE B  92
LEU A  13
MET A  52
1.68A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ASP B 343
LEU B 339
PHE B 346
ILE B 351
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASP A6928
LEU A6848
PHE A7003
ILE A6925
1.55A
SAH  A7102 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.20A
FMT  A7108 (-3.4A)
None
FMT  A7108 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.17A
FMT  A7108 (-3.4A)
None
FMT  A7108 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.18A
FMT  A7108 (-3.4A)
None
FMT  A7108 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASP C6928
LEU C6848
PHE C7003
ILE C6925
1.55A
SAH  C7102 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU C6924
LEU C6959
ILE C7005
PHE C6985
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU C6848
PHE C6991
ILE C6969
PHE C7003
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE B 131
PHE B  66
ILE B 130
TYR B 123
1.63A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 131
PHE D  66
ILE D 130
TYR D 123
1.67A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE A 131
PHE A  66
ILE A 130
TYR A 123
1.62A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE A 131
PHE A  66
ILE A 130
TYR A 123
1.62A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE C 131
PHE C  66
ILE C 130
TYR C 123
1.61A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE C 131
PHE C  66
ILE C 130
TYR C 123
1.60A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 131
PHE D  66
ILE D 130
TYR D 123
1.69A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE A 131
PHE A  66
ILE A 130
TYR A 123
1.63A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 131
PHE D  66
ILE D 130
TYR D 123
1.67A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE B 131
PHE B  66
ILE B 130
TYR B 123
1.65A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE D 131
PHE D  66
ILE D 130
TYR D 123
1.67A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE A 131
PHE A  66
ILE A 130
TYR A 123
1.64A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE B 131
PHE B  66
ILE B 130
TYR B 123
1.63A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE B 131
PHE B  66
ILE B 130
TYR B 123
1.63A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE C 131
PHE C  66
ILE C 130
TYR C 123
1.60A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
ILE C 131
PHE C  66
ILE C 130
TYR C 123
1.60A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C6924
LEU C6959
ILE C7005
PHE C6985
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
ASP A6928
LEU A6848
PHE A7003
ILE A6925
1.56A
SFG  A7103 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ILE C6969
VAL C6992
GLU C6971
LEU C6825
ASN C7031
1.79A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
ASP C6928
LEU C6848
PHE C7003
ILE C6925
1.56A
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C6848
PHE C6991
ILE C6969
PHE C7003
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B   3
LEU B  43
PHE B  56
ILE B  28
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL B 276
PHE B 330
LEU B 298
ILE B 323
1.40A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL A 276
PHE A 330
LEU A 298
ILE A 323
1.40A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A   3
LEU A  43
PHE A  56
ILE A  28
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.08A
None
None
APR  A 201 (-3.4A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  46
1.05A
None
None
APR  C 201 (-3.5A)
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.04A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.77A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.04A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.80A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.05A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.05A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.04A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.78A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.09A
None
None
APR  B 201 (-3.3A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.77A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.03A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.79A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.77A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.75A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.02A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.03A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.04A
None
None
APR  D 201 ( 3.7A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ASN D  40
HIS D  94
ALA D  39
GLY D  97
1.78A
APR  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ILE A6969
VAL A6992
GLU A6971
LEU A6825
ASN A7031
1.77A20.13
None
None
GTA  A7102 (-4.1A)
GTA  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
LEU B4345
ASP B4344
LEU B4365
ILE B4352
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6848
PHE A6991
ILE A6969
PHE A7003
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASN A6975
HIS A7023
ALA A6976
TYR A6979
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
ASP A6928
LEU A6848
PHE A7003
ILE A6925
1.56A
SAH  A7101 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A7005
PHE A6985
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
MET A7068
LEU A7060
MET A7058
ILE A7080
1.78A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wqd NSP8
(SARS-CoV-2)		4 / 7
VAL B 130
PHE B 147
ASN B 105
ILE B 120
1.48A18.33
None
None
EDO  B 301 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
VAL A  66
PHE B  92
LEU A  13
MET A  52
1.61A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 9
ILE B 107
VAL A  66
PHE B  92
LEU A  13
MET A  52
1.79A15.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wqd NSP8
(SARS-CoV-2)		4 / 7
VAL D 130
PHE D 147
ASN D 105
ILE D 120
1.52A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wqd NSP8
(SARS-CoV-2)		4 / 6
LEU B 117
LEU B 128
ILE B 132
PHE B 147
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6wqd NSP8
(SARS-CoV-2)		4 / 6
LEU D 117
LEU D 128
ILE D 132
PHE D 147
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
VAL C  66
PHE D  92
LEU C  13
MET C  52
1.70A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		6y84 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLU A 290
ASP A 295
PHE A   8
ARG A 298
1.77A22.73
None
DMS  A 403 (-4.1A)
DMS  A 403 (-3.8A)
DMS  A 403 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A10.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A11.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A10.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A10.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A10.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.65A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.66A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL B  83
MET B  90
MET C  52
ILE C  39
1.75A16.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL C  66
PHE D  92
LEU C  13
MET C  52
1.79A14.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL D 130
PHE D 147
ASN D 105
ILE D 120
1.54A16.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU B 117
LEU B 128
ILE B 132
PHE B 147
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL A  66
PHE B  92
LEU A  56
ILE B 107
1.74A14.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL B 130
PHE B 147
ASN B 105
ILE B 120
1.59A16.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL D  83
MET D  90
MET A  52
ILE A  39
1.75A16.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU D 117
LEU D 128
ILE D 132
PHE D 147
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 9
ILE D 107
VAL C  66
PHE D  92
LEU C  13
MET C  52
1.76A15.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL C  66
PHE D  92
LEU C  56
ILE D 107
1.74A14.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ILE A  91
PHE A  26
ILE A  90
TYR A  83
1.67A2.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
VAL A  32
PHE A  13
ASN A  37
ILE A  34
1.48A16.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ILE A  91
PHE A  26
ILE A  90
TYR A  83
1.68A2.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ILE A  91
PHE A  26
ILE A  90
TYR A  83
1.67A2.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ILE A  91
PHE A  26
ILE A  90
TYR A  83
1.67A2.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU E 455
LEU E 452
ILE E 472
PHE E 490
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU E 455
LEU E 452
ILE E 472
PHE E 490
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6ym0 LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
VAL E 382
PHE E 515
LEU E 390
ILE L  34
1.76A22.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU E 455
LEU E 452
ILE E 472
PHE E 490
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU A 455
LEU A 452
ILE A 472
PHE A 490
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.77A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  46
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.77A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  47
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.75A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  47
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.79A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.79A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  47
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN E  54
HIS E  94
ALA E  50
GLY E  46
1.16A
None
None
EPE  E 202 (-3.1A)
EPE  E 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN E  54
HIS E  94
ALA E  50
GLY E  47
1.41A
None
None
EPE  E 202 (-3.1A)
EPE  E 202 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN E  54
HIS E  94
ALA E  50
GLY E  46
1.08A
None
None
APR  E 201 (-3.4A)
APR  E 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN A  54
HIS A  94
ALA A  50
GLY A  46
1.09A
None
None
APR  A 201 (-3.4A)
APR  A 201 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  46
1.08A
None
None
APR  C 201 (-3.6A)
APR  C 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN D  54
HIS D  94
ALA D  50
GLY D  46
1.07A
None
None
APR  D 201 (-3.6A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.10A
None
None
APR  B 201 (-3.5A)
EDO  B 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.78A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.76A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  46
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  54
HIS B  94
ALA B  50
GLY B  47
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.74A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.79A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.77A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.78A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  46
1.15A
None
None
MES  C 201 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.79A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.80A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ASN C  54
HIS C  94
ALA C  50
GLY C  47
1.45A
None
None
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6zsl SARS-COV-2 HELICASE
NSP13
(SARS-CoV-2)		4 / 6
GLU B 447
ILE B 448
ILE B 572
TRP B 506
1.34A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.76A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL A 330
MET A 380
LEU B 103
ILE B 107
1.54A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		7btf NSP12
(SARS-CoV-2)		4 / 6
GLU A  83
ILE A  86
PHE A 101
ILE A 201
1.66A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL B  83
LEU A 372
MET A 566
ILE A 562
1.15A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7btf NSP12
(SARS-CoV-2)		4 / 7
VAL A 472
LEU A 308
ASN A 312
MET A 629
1.62A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		7btf NSP12
(SARS-CoV-2)		4 / 6
GLU A  83
ILE A  86
PHE A 101
ILE A 201
1.66A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		7btf NSP12
(SARS-CoV-2)		4 / 6
GLU A  83
ILE A  86
PHE A 101
ILE A 201
1.66A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 237
MET A 124
ASP A 211
TYR A 217
TRP A 216
1.80A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 316
LEU A 282
PHE A 317
PHE A 321
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7btf NSP8
(SARS-CoV-2)		4 / 7
VAL D 130
PHE D 147
ASN D 105
ILE D 120
1.42A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
ASP A 218
PHE A 219
ILE A 223
PHE A 222
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B  95
ASP B  99
LEU B 103
ILE A 333
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		7btf NSP12
(SARS-CoV-2)		4 / 6
GLU A  83
ILE A  86
PHE A 101
ILE A 201
1.66A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
GLU A 370
TYR A 374
ASP A 336
PHE B  92
1.78A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 103
LEU B  95
ILE A 333
PHE A 340
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PHE A 140
HIS A 164
GLY A 149
TYR A 161
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
LEU D 184
ASP D 161
LEU D 169
ILE D 156
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
PHE A  45
HIS A 133
ALA A  46
TYR A 129
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL A 330
MET A 380
LEU B 103
ILE B 107
1.47A16.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL B  83
LEU A 372
MET A 566
ILE A 562
1.27A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv1 NSP8
(SARS-CoV-2)		4 / 7
VAL D 130
PHE D 147
ASN D 105
ILE D 120
1.39A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
VAL A 472
LEU A 308
ASN A 312
MET A 629
1.64A16.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A  39
HIS A 725
ALA A  43
TYR A  38
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 316
LEU A 282
PHE A 317
PHE A 321
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 103
LEU B  95
ILE A 333
PHE A 340
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL B  83
LEU A 372
MET A 566
ILE A 562
1.27A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL A 330
MET A 380
LEU B 103
ILE B 107
1.60A16.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
VAL A 472
LEU A 308
ASN A 312
MET A 629
1.68A16.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 862
LEU A 891
PHE A 859
ILE A 847
1.65A
 U  P  17 ( 4.9A)
None
None
U  P  17 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 316
LEU A 282
PHE A 317
PHE A 321
1.80A
None