Ligand ID: 6K9


Drugbank ID:
DB08871
(Eribulin)


Indication:
For the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic cancer.

Get human targets for 6K9 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '6K9' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.45A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A15.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 247
ILE A 200
VAL A 202
1.69A15.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 7
VAL B 915
GLU A1202
ASN C 919
ILE C 923
1.45A16.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A21.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A21.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU B 253
VAL B 261
ILE B 200
VAL B 202
1.52A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU D 253
VAL D 247
ILE D 200
VAL D 202
1.68A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU D 253
VAL D 261
ILE D 200
VAL D 202
1.63A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.54A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU C 253
VAL C 261
ILE C 200
VAL C 202
1.53A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.52A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 247
ILE A 200
VAL A 202
1.71A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU C  35
GLU C  47
ILE D 106
VAL C  53
1.50A11.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 727
VAL A 742
ILE A 696
VAL A 475
1.65A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU A 673
VAL A 667
ASN B 118
LYS A 676
VAL A 675
1.68A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ASN A 628
GLU A 350
PRO B 116
TYR A 346
LEU A 329
1.78A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU B  95
GLU A 370
ILE B 107
VAL A 341
1.17A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU D 117
VAL D 130
ILE C  68
VAL D 115
1.60A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 361
VAL A 335
ASN A 356
VAL A 342
1.70A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
VAL A 742
ILE A 696
LYS A 478
VAL A 475
1.33A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLU A 802
ASN A 695
ILE A 757
VAL A 764
1.54A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 749
VAL A 476
ASN A 705
VAL A 472
1.55A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU B 184
ILE A 450
LYS A 391
VAL B 131
1.46A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU C  14
VAL C  22
ILE D 120
VAL C  58
1.67A11.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU A 163
GLU A 146
ILE A  86
VAL A  67
1.34A20.04
None
GOL  A 402 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 11
SER B  65
ASP B  66
GLU B  64
PRO B  74
LEU B  75
1.78A
None
None
None
None
SO4  B 201 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6vxs NSP3
(SARS-CoV-2)		4 / 7
LEU B 123
VAL B 121
GLU B 120
VAL B 151
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU B 865
GLU B 819
ASN B 777
ILE B1018
1.48A15.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
LEU C 513
VAL C 341
GLU C 340
LYS C 356
1.70A15.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 247
ILE A 200
VAL A 202
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL A  24
GLU A  25
ILE A 131
VAL A  49
1.59A
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
LEU A 123
VAL A 121
GLU A 120
VAL A 151
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
LEU B 123
VAL B 121
GLU B 120
VAL B 151
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
LEU C7078
GLU C7082
ASN C7066
LYS C7061
1.33A16.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU B 185
GLU B 238
ILE B 314
VAL B 235
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU C 185
GLU C 238
ILE C 314
VAL C 235
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wen NSP3
(SARS-CoV-2)		4 / 7
LEU A 123
VAL A 121
GLU A 120
VAL A 151
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wen NSP3
(SARS-CoV-2)		4 / 7
VAL A  24
GLU A  25
ILE A 131
VAL A  49
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wey NSP3
(SARS-CoV-2)		4 / 7
LEU A 327
VAL A 325
GLU A 324
VAL A 355
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wiq NSP8
(SARS-CoV-2)		4 / 7
VAL B 186
ASN B 109
ILE B 106
VAL B 130
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wiq NSP8
(SARS-CoV-2)		4 / 7
VAL B 186
ASN B 105
ILE B 106
VAL B 130
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
LEU C7078
GLU C7082
ASN C7066
LYS C7061
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LEU C  56
ASN D  75
ILE D 157
VAL C 158
1.70A
None
MES  D 201 (-3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LEU A  56
ASN B  75
ILE B 157
VAL A 158
1.70A
None
MES  B 201 (-3.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wkq NSP16
(SARS-CoV-2)		4 / 7
LEU C7078
GLU C7082
ASN C7066
LYS C7061
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU B  43
VAL B  25
ASN B  12
VAL B  23
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU B 168
GLU B 146
ASN B 164
VAL B  67
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU A 168
GLU A 146
ILE A  86
VAL A  67
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU B 163
GLU B 146
ILE B  86
VAL B  67
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU B  73
VAL B 142
ILE B 100
VAL B 122
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU A  73
VAL A 142
ILE A 100
VAL A 122
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU A  43
VAL A  25
ASN A  12
VAL A  23
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
LEU A 163
GLU A 146
ILE A  86
VAL A  67
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A  67
VAL A  20
ASN A  63
ILE A  78
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU D 123
VAL D 121
GLU D 120
VAL D 151
1.49A
None
None
APR  A 201 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU B 123
VAL B 121
GLU B 120
VAL B 151
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU C 123
VAL C 121
GLU C 120
VAL C 151
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 123
VAL A 121
GLU A 120
VAL A 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6wqd NSP8
(SARS-CoV-2)		5 / 11
ASN D 140
VAL D 131
ASP D 134
THR D 137
LEU D 117
1.66A15.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU D  91
VAL C  11
ILE A  39
VAL A  11
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wqd NSP8
(SARS-CoV-2)		4 / 7
VAL B 186
ASN B 109
ILE B 106
VAL B 130
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU B  91
VAL A  11
ILE C  39
VAL C  11
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A  75
VAL A  20
ASN A  95
VAL A  18
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 247
ILE A 200
VAL A 202
1.70A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.52A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
LEU D  91
VAL C  11
ILE A  39
VAL A  11
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
VAL B 186
ASN B 105
ILE B 106
VAL B 130
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
LEU B  91
VAL A  11
ILE C  39
VAL C  11
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL A 341
GLU A 340
ASN A 394
LYS A 356
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU A 513
VAL A 341
GLU A 340
LYS A 356
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU E 513
VAL E 341
GLU E 340
LYS E 356
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU E 513
VAL E 341
GLU E 340
LYS E 356
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU A 513
VAL A 341
GLU A 340
LYS A 356
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN A 115
VAL D  95
SER D  80
PRO D 125
LEU D 127
1.44A18.41
EDO  D 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU D 123
VAL D 121
GLU D 120
VAL D 151
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN D 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.48A
EDO  D 201 (-3.6A)
None
None
None
EDO  A 202 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
SER D  65
ASP D  66
GLU D  64
PRO D  74
LEU D  75
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  24
GLU C  25
ILE C 131
VAL C  49
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  24
GLU B  25
ILE B 131
VAL B  49
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN A 115
VAL D  95
SER D  80
PRO D 125
LEU D 127
1.42A
EDO  D 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN D 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.49A18.41
EDO  D 201 (-3.6A)
None
None
None
EDO  A 202 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
SER E  65
ASP E  66
GLU E  64
PRO E  74
LEU E  75
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
SER C  65
ASP C  66
GLU C  64
PRO C  74
LEU C  75
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU D 123
VAL D 121
GLU D 120
VAL D 151
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU A 123
VAL A 121
GLU A 120
VAL A 151
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
SER D  65
ASP D  66
GLU D  64
PRO D  74
LEU D  75
1.80A
None
None
None
None
EDO  D 202 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN D 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.54A18.41
EDO  A 207 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN D 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.52A
EDO  A 207 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU C 123
VAL C 121
GLU C 120
VAL C 151
1.70A
None
None
MG  C 202 (-1.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN A 115
VAL C  95
SER C  80
PRO C 125
LEU C 127
1.36A
EDO  A 202 ( 3.5A)
None
EDO  A 204 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN C 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.43A18.41
EDO  A 202 (-3.6A)
None
EDO  A 204 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN A 115
VAL C  95
SER C  80
PRO C 125
LEU C 127
1.38A18.41
EDO  A 202 ( 3.5A)
None
EDO  A 204 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU A 123
VAL A 121
GLU A 120
VAL A 151
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
LEU B 123
VAL B 121
GLU B 120
VAL B 151
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ASN C 115
VAL A  95
SER A  80
PRO A 125
LEU A 127
1.40A
EDO  A 202 (-3.6A)
None
EDO  A 204 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  24
GLU B  25
ILE B 131
VAL B  49
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU B 184
ILE A 450
LYS A 391
VAL B 131
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU B 184
ASN A 447
ILE A 450
VAL B 131
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 786
VAL A 785
ASN A 695
ILE A 696
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
VAL A 742
ILE A 696
LYS A 478
VAL A 475
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU A 673
VAL A 667
ASN B 118
LYS A 676
VAL A 675
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 749
VAL A 476
ASN A 705
VAL A 472
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 261
ILE A 200
VAL A 202
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 253
VAL A 247
ILE A 200
VAL A 202
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
VAL A 742
ILE A 696
LYS A 478
VAL A 475
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU B 184
ASN A 447
ILE A 450
LYS A 391
VAL B 131
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP8
(SARS-CoV-2)		4 / 7
LEU D 184
VAL D 131
ILE D 156
VAL D 186
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU A 673
VAL A 667
ASN B 118
LYS A 676
VAL A 675
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLU A 802
ASN A 695
ILE A 757
VAL A 764
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU C  35
GLU C  47
ILE D 106
VAL C  53
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
LEU A 786
VAL A 785
ASN A 695
ILE A 696
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
LEU A 749
VAL A 476
ASN A 705
VAL A 472
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLU A 802
ASN A 695
ILE A 757
VAL A 764
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU B 184
ASN A 447
ILE A 450
LYS A 391
VAL B 131
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
LEU A 749
VAL A 476
ASN A 705
VAL A 472
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ASN A 628
GLU A 350
PRO B 116
TYR A 346
LEU A 329
1.77A18.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU B  95
ASN B 104
ILE B 107
VAL A 341
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
VAL A 742
ILE A 696
LYS A 478
VAL A 475
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 7
LEU A 673
VAL A 667
ASN B 118
LYS A 676
VAL A 675
1.65A
None