Ligand ID: 308


Drugbank ID:
DB00915
(Amantadine)


Indication:
For the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.

Get human targets for 308 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '308' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5r7y 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.53A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 144
ALA A 116
SER A 123
SER A 121
1.67A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 147
ALA A 116
SER A 123
SER A 121
1.42A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
VAL A 125
SER A  10
ALA A 116
SER A 123
1.58A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.56A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.57A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.22A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 121
SER A 144
ALA A 116
SER A 123
1.67A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
LEU A 208
SER A 267
ALA A 266
1.42A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A 116
SER A 123
SER A 147
SER A 121
1.63A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 121
SER A 147
ALA A 116
SER A 123
1.42A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 147
1.42A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 144
1.67A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
SER A 254
ILE A 259
ALA A 260
1.37A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 6
LEU E 922
ILE F 923
ILE D 923
ALA D 924
0.83A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.22A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.21A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.73A6.71

None
None
DMS  A 403 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 121
ALA D 116
SER D 123
SER D 147
1.63A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 121
ALA C 116
SER C 123
SER C 147
1.74A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA D 116
SER D 123
SER D 147
SER D 121
1.67A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 9
GLY A  11
SER C 121
LEU C 115
SER C 123
GLY C  15
1.80A6.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 121
ALA C 116
SER C 123
SER C 147
1.72A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA B 285
SER B 284
SER D 284
ALA D 285
1.73A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA C 116
SER C 123
SER C 147
SER C 121
1.78A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
VAL C 125
SER C  10
ALA C 116
SER C 123
1.61A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU D 268
LEU D 287
ILE D 281
ALA D 206
1.22A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ALA C 285
SER C 284
SER A 284
ALA A 285
1.68A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.28A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 9
SER D 121
GLY D 120
LEU D 115
SER D 123
GLY D 146
1.77A6.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
VAL D 125
SER D  10
ALA D 116
SER D 123
1.58A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 121
ALA D 116
SER D 123
SER D 147
1.59A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU B 268
LEU B 287
ILE B 281
ALA B 206
1.24A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU C 268
LEU C 287
ILE C 281
ALA C 206
1.20A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 125
SER A  10
ALA A 116
SER A 123
1.56A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.24A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 8
ALA A  56
ALA C 156
ALA A 156
ALA A  51
SER A  52
1.65A10.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
LEU A 527
LEU A 372
SER A 561
ILE A 562
1.23A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 502
SER A 561
ALA A 512
SER A 564
1.66A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6m71 NSP8
(SARS-CoV-2)		5 / 9
ILE B 156
SER B 170
LEU B 180
SER B 173
LEU B 184
1.72A9.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
VAL A 560
SER A 564
SER A 561
ALA A 660
1.77A2.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 702
SER A 784
1.68A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m71 NSP12
NSP7
(SARS-CoV-2)		4 / 6
VAL C  11
SER C  15
SER C  10
ALA A 443
1.43A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 702
SER A 784
1.30A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 706
SER A 784
1.58A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
VAL A 662
ALA A 558
SER A 681
SER A 561
1.75A2.46

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 777
SER A 784
1.44A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ALA A 771
SER A 778
ALA A 777
SER A 709
1.77A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 6
LEU A 638
LEU A 575
ILE A 579
ILE A 589
ALA A 688
1.50A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER C 968
SER C1003
LEU A1001
SER A 758
GLY C 999
1.29A2.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ALA C 672
ALA C 609
SER C 691
ALA C 688
1.27A2.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B 120
ILE B  80
ILE B 100
ALA B 109
0.87A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6vxs NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6vxs NSP3
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.59A
SO4  B 204 (-4.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER B 968
SER B1003
LEU C1001
SER C 758
GLY B 999
1.30A2.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
SER A 940
ALA A 944
SER A 943
SER A 937
1.48A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER C 968
SER C1003
LEU A1001
SER A 758
GLY C 999
1.44A2.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
SER B 940
ALA B 944
SER B 943
SER B 937
1.35A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER C 691
SER C 673
ALA C 672
ALA C 609
1.27A2.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w02 NSP3
(SARS-CoV-2)		5 / 8
ALA B  38
ALA B 124
SER B 139
ALA B 129
SER B 128
1.63A10.18
APR  B 201 (-3.4A)
None
None
APR  B 201 (-3.6A)
APR  B 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w02 NSP3
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.41A14.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
LEU C 452
LEU C 492
ILE C 468
ALA C 352
1.75A12.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 9
GLY H  97
ILE H  98
LEU C 387
SER H  99
GLY C 381
1.73A11.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.03A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A7074
ALA A6986
SER A6964
ALA A6858
1.71A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6986
SER A6964
ALA A6858
SER A7074
1.71A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ALA A6905
SER A6907
SER A6896
ALA A6877
SER A6903
1.76A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.68A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6832
SER A7039
SER A7041
ALA A6997
1.66A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
SER A6896
ALA A6877
SER A6903
ALA A6905
SER A6907
1.76A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A7041
ALA A6997
ALA A6832
SER A7039
1.66A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6802
ALA A6997
ALA A6832
SER A7038
1.74A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
SER A6872
ALA A6877
ALA B4324
SER B4325
1.76A11.36
SAM  A7104 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
ALA B4324
SER B4325
SER A6872
ALA A6877
1.76A11.19
None
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
VAL B4295
SER B4325
ALA A6877
SER A6872
1.73A11.43
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6858
SER A7074
ALA A6986
SER A6964
1.71A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7069
SER A7071
1.46A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6893
ILE A6866
SER A6896
ALA A6870
1.64A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
ALA A6877
ALA B4324
SER B4325
SER A6872
1.76A11.36
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6997
ALA A6832
SER A7038
ALA A6802
1.74A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6997
ALA A6832
SER A7039
SER A7041
1.66A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
VAL A6995
ALA A6832
SER A6831
SER A6998
1.76A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7073
ILE A7065
ILE A7080
ALA A6960
1.67A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A7079
ALA A6858
1.55A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ALA A6832
SER A7038
ALA A6802
ALA A6997
1.74A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6978
ILE A6969
SER A6927
ALA A6966
1.73A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU A7010
LEU A7070
ILE A7065
SER A7071
ILE A7069
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7072
LEU A7073
ILE A7079
ALA A7056
1.53A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A6955
ILE A6951
1.70A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6964
ALA A6858
SER A7074
ALA A6986
1.71A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7072
LEU A7073
ILE A7080
ILE A7065
1.34A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6981
LEU A6978
ILE A6967
ILE A6951
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6825
ILE A7035
SER A6999
ALA A7002
1.71A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6848
ILE A6967
SER A6964
ILE A6925
1.67A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7004
LEU A6978
ILE A6951
ILE A6955
1.38A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 8
ALA A6877
SER A6903
ALA A6905
SER A6907
SER A6896
1.76A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6893
SER A6903
ALA A6870
1.69A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6893
SER A6903
ALA A6877
1.73A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7004
ILE A6955
SER A6927
ILE A6951
1.59A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6924
ILE A6925
ILE A6866
1.56A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7078
LEU A7073
ILE A7065
SER A7071
1.57A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7065
ILE A7080
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.54A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
VAL A 125
SER A  10
ALA A 116
SER A 123
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.59A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 160
LEU A 164
ILE A  18
SER A 166
1.71A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A 129
ALA A  38
ALA A 124
SER A 139
1.46A10.26
AMP  A 201 ( 3.4A)
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B 124
SER B 139
ALA B 129
ALA B  38
1.49A10.26
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B 112
SER B 139
ALA B 129
ALA B  38
1.72A10.26
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A  27
ALA A  52
ALA A  38
ALA A 124
1.73A10.26
None
AMP  A 201 ( 4.0A)
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B 140
ILE B 137
SER B 139
ALA B 129
1.39A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A 124
ALA A  27
ALA A  52
ALA A  38
1.73A10.26
None
None
AMP  A 201 ( 4.0A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
SER A 139
ALA A 129
ALA A  38
ALA A 124
1.46A10.26
None
AMP  A 201 ( 3.4A)
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B 126
LEU B 164
ILE B  18
ALA B 154
1.64A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 126
LEU A 164
ILE A  18
ALA A 154
1.71A13.76
AMP  A 201 ( 4.4A)
None
None
AMP  A 201 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B  12
LEU B 164
ILE B 137
SER B 166
1.72A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
SER B 139
ALA B 129
ALA B  38
ALA B 124
1.49A10.26
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B 129
ALA B  38
ALA B 112
SER B 139
1.72A10.26
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
SER B 139
ALA B 129
ALA B  38
ALA B 112
1.72A10.26
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B 160
LEU B 164
ILE B  18
SER B 166
1.73A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B  38
ALA B 112
SER B 139
ALA B 129
1.72A10.26
MES  B 201 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 160
LEU A 164
SER A 139
ILE A 137
1.68A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 140
ILE A 137
SER A 139
ALA A 129
1.46A13.76
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B 129
ALA B  38
ALA B 124
SER B 139
1.49A10.26
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B 153
LEU B 126
SER B 128
ALA B  38
1.71A13.76
None
None
MES  B 201 ( 4.5A)
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 126
LEU A 140
ILE A 137
ALA A 134
1.60A13.76
AMP  A 201 ( 4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.58A9.38
None
None
None
MES  B 201 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA B  38
ALA B 124
SER B 139
ALA B 129
1.49A10.26
MES  B 201 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.56A
None
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.58A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A 124
SER A 139
ALA A 129
ALA A  38
1.46A10.26
None
None
AMP  A 201 ( 3.4A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A  38
ALA A 124
ALA A  27
ALA A  52
1.73A10.26
AMP  A 201 ( 3.9A)
None
None
AMP  A 201 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A  38
ALA A 124
SER A 139
ALA A 129
1.46A10.26
AMP  A 201 ( 3.9A)
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 8
ALA A  52
ALA A  38
ALA A 124
ALA A  27
1.73A10.26
AMP  A 201 ( 4.0A)
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A7074
ALA A6986
SER A6964
ALA A6858
1.69A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6978
ILE A6951
ILE A6925
ALA A6966
1.48A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6986
SER A6964
ALA A6858
SER A7074
1.69A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6959
ILE C6951
ILE C6967
ALA C6966
1.05A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6825
ILE C7035
SER C6999
ALA C7002
1.69A13.08
None
None
FMT  C7108 ( 2.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C7038
ALA C6832
ALA C6843
SER C7041
1.46A9.38
FMT  C7111 ( 4.8A)
FMT  C7111 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7004
ILE A6955
SER A6927
ILE A6951
1.59A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A7041
ALA A6997
ALA A6832
SER A7039
1.57A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6883
LEU C6924
ILE C6925
ILE C6866
1.55A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7078
LEU A7073
ILE A7065
SER A7071
1.60A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6978
ILE A6969
SER A6927
ALA A6966
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6832
SER A7038
ALA A6802
ALA A6997
1.54A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7078
LEU C7073
ILE C7065
SER C7071
1.62A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6832
SER C7039
SER C7041
ALA C6997
1.61A9.38
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7072
LEU A7073
ILE A7080
ILE A7065
1.30A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6843
SER A7041
SER A7038
ALA A6832
1.48A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6825
ILE A7035
SER A6999
ALA A7002
1.71A13.08
None
None
FMT  A7104 ( 2.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6981
LEU A6978
ILE A6967
ILE A6951
1.17A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7072
LEU C7078
ILE C7080
ILE C7065
1.69A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7010
LEU C7070
ILE C7069
SER C7071
1.27A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6978
ILE C6951
ILE C6925
ALA C6966
1.52A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.54A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6924
ILE A6925
ILE A6866
1.54A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7069
SER A7071
1.30A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6997
ALA C6832
SER C7039
SER C7041
1.61A9.38
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6997
ALA A6832
SER A7039
SER A7041
1.57A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A6955
ILE A6951
1.69A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6905
SER C6896
ALA C6877
SER C6903
1.61A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6981
LEU C6978
ILE C6967
ILE C6925
1.74A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6843
SER C7041
SER C7038
ALA C6832
1.46A9.38
None
None
FMT  C7111 ( 4.8A)
FMT  C7111 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7072
LEU C7073
ILE C7080
ILE C7065
1.29A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C7041
ALA C6997
ALA C6832
SER C7039
1.61A9.38
None
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A6964
ALA A6858
SER A7074
ALA A6986
1.69A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C7041
SER C7038
ALA C6832
ALA C6843
1.46A9.38
None
FMT  C7111 ( 4.8A)
FMT  C7111 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7078
LEU C7060
ILE C7065
ALA C6960
1.54A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7072
LEU A7073
ILE A7079
ALA A7056
1.52A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6848
ILE C6967
SER C6964
ILE C6925
1.57A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6978
ILE C6925
SER C6964
ALA C6966
1.62A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7010
LEU C7070
ILE C7065
ILE C7080
1.15A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A7038
ALA A6832
ALA A6843
SER A7041
1.48A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6877
SER C6903
ALA C6905
SER C6896
1.61A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 6
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.45A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6986
SER C6964
ALA C6858
SER C7074
1.70A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.58A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6893
ILE A6866
SER A6927
ILE A6925
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C6896
ALA C6877
SER C6903
ALA C6905
1.61A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 6
VAL D4295
SER D4325
ALA C6877
SER C6872
1.79A11.27
None
None
None
SAM  C7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 6
VAL B4295
SER B4325
ALA A6877
SER A6872
1.78A11.27
None
None
None
SAM  A7102 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7004
LEU C6978
ILE C6951
ILE C6925
1.62A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A7041
SER A7038
ALA A6832
ALA A6843
1.48A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7065
ILE A7080
1.19A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.61A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6832
ALA A6843
SER A7041
SER A7038
1.48A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6893
SER A6903
ALA A6870
1.64A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
LEU A6893
SER A6903
ALA A6877
1.71A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6997
ALA A6832
SER A7038
ALA A6802
1.54A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7072
LEU A7078
ILE A7080
ILE A7065
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7004
LEU C6978
ILE C6951
ILE C6955
1.52A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6893
ILE C6866
SER C6896
ALA C6870
1.64A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6832
SER A7039
SER A7041
ALA A6997
1.57A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
SER C6927
SER C6896
LEU C6893
LEU C6883
GLY C6871
1.71A9.38
None
None
None
None
SAM  C7105 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6978
ILE C6969
SER C6927
ALA C6966
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6924
LEU A6959
ILE A7079
ALA A6858
1.59A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C6964
ALA C6858
SER C7074
ALA C6986
1.70A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6978
ILE A6925
SER A6964
ALA A6966
1.63A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6858
SER C7074
ALA C6986
SER C6964
1.70A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6883
LEU C6893
SER C6903
ALA C6870
1.64A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7004
LEU A6978
ILE A6951
ILE A6955
1.46A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
SER A6927
SER A6896
LEU A6893
LEU A6883
GLY A6871
1.70A9.38
None
None
None
None
SAM  A7102 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA C6832
ALA C6843
SER C7041
SER C7038
1.46A9.38
FMT  C7111 ( 3.6A)
None
None
FMT  C7111 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7065
SER A7071
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C7074
ALA C6986
SER C6964
ALA C6858
1.70A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 6
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.46A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6848
ILE A6967
SER A6964
ILE A6925
1.59A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6893
ILE A6866
SER A6896
ALA A6870
1.66A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7004
LEU A6978
ILE A6951
ILE A6925
1.62A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6883
LEU C6893
SER C6903
ALA C6877
1.73A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.09A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6858
SER A7074
ALA A6986
SER A6964
1.69A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A7073
ILE A7065
ILE A7080
ALA A6960
1.64A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C7072
LEU C7073
ILE C7079
ALA C7056
1.52A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6924
LEU C6959
ILE C7079
ALA C6858
1.61A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ALA A6802
ALA A6997
ALA A6832
SER A7038
1.54A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ALA B 249
SER B 262
SER B 245
ALA B 246
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA A  86
SER A  85
ALA A 153
SER A  78
1.32A9.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
SER C 245
ALA C 246
ALA C 249
SER C 262
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
SER B 245
ALA B 246
ALA B 249
SER B 262
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
SER C 262
SER C 245
ALA C 246
ALA C 249
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ALA C 249
SER C 262
SER C 245
ALA C 246
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA B  86
SER B  85
ALA B 153
SER B  78
1.36A9.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
VAL A 165
SER A 262
ALA A 246
SER A 245
1.73A9.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ALA C  86
SER C  85
ALA C 153
SER C  78
1.34A9.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
SER B 262
SER B 245
ALA B 246
ALA B 249
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ALA B 246
ALA B 249
SER B 262
SER B 245
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ALA C 246
ALA C 249
SER C 262
SER C 245
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wcf NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wcf NSP3
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.58A
None
None
None
MES  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wen NSP3
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		4 / 6
VAL A 346
SER A 343
ALA A 316
SER A 332
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wey NSP3
(SARS-CoV-2)		5 / 6
LEU A 364
LEU A 368
ILE A 341
SER A 343
ALA A 338
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wey NSP3
(SARS-CoV-2)		5 / 6
LEU A 364
LEU A 368
ILE A 341
SER A 343
ALA A 333
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA B 102
SER A  54
ALA B 152
SER B 151
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER A  54
ALA B 152
SER B 151
ALA B 102
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA B 152
SER B 151
ALA B 102
SER A  54
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wiq NSP7
(SARS-CoV-2)		4 / 6
ALA A  48
ALA A  42
SER A   1
SER A   4
1.77A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA C 264
SER D 312
ALA C 273
SER D 310
1.56A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA B 264
SER A 312
ALA B 273
SER A 310
1.56A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA D 311
SER D 312
ALA C 308
SER D 318
1.79A11.93
 CL  C 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA E 264
SER F 312
ALA E 273
SER F 310
1.52A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA A 264
SER B 312
ALA A 273
SER B 310
1.56A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA E 311
SER E 310
ALA F 308
SER E 318
1.30A11.93
 CL  F 401 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA D 264
SER C 312
ALA D 273
SER C 310
1.57A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA F 311
SER F 310
ALA E 308
SER F 318
1.30A11.93
 CL  E 401 ( 4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA C 311
SER C 310
ALA D 308
SER C 318
1.30A11.93
 CL  D 401 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA F 264
SER E 312
ALA F 273
SER E 310
1.57A11.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA D 311
SER D 310
ALA C 308
SER D 318
1.29A11.93
 CL  C 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA A 311
SER A 310
ALA B 308
SER A 318
1.29A11.93
 CL  B 401 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA B 311
SER B 310
ALA A 308
SER B 318
1.30A11.93
 CL  A 401 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ALA C 311
SER C 312
ALA D 308
SER C 318
1.80A11.93
 CL  D 401 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU C7010
LEU C7070
ILE C7065
ILE C7080
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6981
LEU A6978
ILE A6967
ILE A6951
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
VAL B4295
SER B4325
ALA A6877
SER A6872
1.71A
None
None
None
SAH  A7102 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
VAL D4295
ALA D4324
SER D4325
SER C6872
1.40A
None
None
None
SAH  C7102 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU C6959
ILE C6951
ILE C6967
ALA C6966
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
VAL D4295
SER D4325
ALA C6877
SER C6872
1.69A
None
None
None
SAH  C7102 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
SER A6927
SER A6896
LEU A6893
LEU A6883
GLY A6871
1.68A6.38
None
None
None
None
SAH  A7102 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
SER A  79
GLY D 170
SER D 105
LEU D  64
GLY D  60
1.77A16.67
 ZN  A 201 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A6981
LEU A6978
ILE A6967
ILE A6951
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C6981
LEU C6978
ILE C6967
ILE C6951
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C7010
LEU C7070
ILE C7065
ILE C7080
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 6
VAL B4295
SER B4325
ALA A6877
SER A6872
1.76A
None
None
None
SFG  A7103 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
SER C6927
SER C6896
LEU C6893
LEU C6883
GLY C6871
1.68A6.38
None
None
None
None
SFG  C7103 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
SER A6927
SER A6896
LEU A6893
LEU A6883
GLY A6871
1.67A6.38
None
None
None
None
SFG  A7103 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7065
ILE A7080
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 6
VAL D4295
SER D4325
ALA C6877
SER C6872
1.78A
None
None
None
SFG  C7103 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 6
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7069
SER A7071
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C7072
LEU C7073
ILE C7080
ILE C7065
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C7010
LEU C7070
ILE C7069
SER C7071
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 6
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C6959
ILE C6951
ILE C6967
ALA C6966
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 6
LEU B 312
LEU B 332
ILE B 307
ILE B 236
ALA B 232
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B 120
ILE B  80
ILE B 100
ALA B 109
0.91A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 6
LEU A 312
LEU A 332
ILE A 307
ILE A 236
ALA A 232
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 120
ILE A  80
ILE A 100
ALA A 109
0.90A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA D 129
SER D 128
ALA D  38
ALA D 124
SER D 139
1.62A
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
APR  D 201 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA A 124
SER A 139
ALA A 129
SER A 128
ALA A  38
1.66A
None
None
APR  A 201 (-3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.60A
None
None
None
APR  B 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA C  38
ALA C 124
SER C 139
ALA C 129
SER C 128
1.64A
APR  C 201 (-3.4A)
None
None
APR  C 201 (-3.7A)
APR  C 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA D 124
SER D 139
ALA D 129
SER D 128
ALA D  38
1.62A
None
None
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.44A
None
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
SER B 139
ALA B 129
SER B 128
ALA B  38
ALA B 124
1.64A
None
APR  B 201 (-3.7A)
APR  B 201 (-4.5A)
APR  B 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
SER C 139
ALA C 129
SER C 128
ALA C  38
ALA C 124
1.64A
None
APR  C 201 (-3.7A)
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA B 124
SER B 139
ALA B 129
SER B 128
ALA B  38
1.64A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-4.5A)
APR  B 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
SER D 139
ALA D 129
SER D 128
ALA D  38
ALA D 124
1.62A
None
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
APR  D 201 (-3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA A  38
ALA A 124
SER A 139
ALA A 129
SER A 128
1.66A
APR  A 201 (-3.5A)
None
None
APR  A 201 (-3.7A)
APR  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA C 124
SER C 139
ALA C 129
SER C 128
ALA C  38
1.64A
None
None
APR  C 201 (-3.7A)
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.44A
None
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.45A
None
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.60A
None
None
None
APR  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL D 142
SER D 139
ALA D 112
SER D 128
1.61A
None
None
None
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA B 129
SER B 128
ALA B  38
ALA B 124
SER B 139
1.64A
APR  B 201 (-3.7A)
APR  B 201 (-4.5A)
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
SER A 139
ALA A 129
SER A 128
ALA A  38
ALA A 124
1.66A
None
APR  A 201 (-3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA D  38
ALA D 124
SER D 139
ALA D 129
SER D 128
1.62A
APR  D 201 (-3.2A)
None
None
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.42A
None
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA A 129
SER A 128
ALA A  38
ALA A 124
SER A 139
1.66A
APR  A 201 (-3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA B  38
ALA B 124
SER B 139
ALA B 129
SER B 128
1.64A
APR  B 201 (-3.3A)
None
None
APR  B 201 (-3.7A)
APR  B 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 8
ALA C 129
SER C 128
ALA C  38
ALA C 124
SER C 139
1.64A
APR  C 201 (-3.7A)
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL C 142
SER C 139
ALA C 112
SER C 128
1.59A
None
None
None
APR  C 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
SER A6927
SER A6896
LEU A6893
LEU A6883
GLY A6871
1.70A6.38
None
None
None
None
SAH  A7101 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
VAL B4295
SER B4325
ALA A6877
SER A6872
1.75A
None
None
None
SO4  A7109 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6981
LEU A6978
ILE A6967
ILE A6951
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A7010
LEU A7070
ILE A7065
ILE A7080
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 6
LEU A6924
ILE A6955
SER A6927
ILE A6967
ALA A6966
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6959
ILE A6951
ILE A6967
ALA A6966
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 152
SER D 151
ALA D 102
SER C  54
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 102
SER C  54
ALA D 152
SER D 151
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  54
ALA D 152
SER D 151
ALA D 102
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER A  54
ALA B 152
SER B 151
ALA B 102
1.28A
None
EDO  B 302 ( 4.3A)
None
EDO  B 302 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA B 102
SER A  54
ALA B 152
SER B 151
1.28A
EDO  B 302 ( 4.2A)
None
EDO  B 302 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA B 152
SER B 151
ALA B 102
SER A  54
1.28A
EDO  B 302 ( 4.3A)
None
EDO  B 302 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.79A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
VAL A 165
SER A 262
ALA A 114
SER A 111
1.71A
None
None
None
PO4  A 502 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A 114
SER A 111
ALA A 116
SER A 262
1.73A8.42
None
PO4  A 502 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
ALA A  86
SER A  85
ALA A 153
SER A  78
1.43A8.42
None
GOL  A 507 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 144
1.58A10.32
None
None
None
DMS  A 405 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 121
SER A 147
ALA A 116
SER A 123
1.45A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.23A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ALA A 116
SER A 123
SER A 147
SER A 121
1.67A10.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 271
LEU A 287
SER A 284
ALA A 285
1.67A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 147
1.45A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.57A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.60A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 121
SER A 144
ALA A 116
SER A 123
1.58A10.32
None
DMS  A 405 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 147
ALA A 116
SER A 123
SER A 121
1.45A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 144
ALA A 116
SER A 123
SER A 121
1.58A10.32
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
SER A 254
ILE A 259
ALA A 260
1.17A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
LEU A 208
SER A 267
ALA A 266
1.42A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ALA D 102
SER C  54
ALA D 152
SER D 151
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ALA D 152
SER D 151
ALA D 102
SER C  54
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
SER A  54
ALA B 152
SER B 151
ALA B 102
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ALA B 102
SER A  54
ALA B 152
SER B 151
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
SER C  54
ALA D 152
SER D 151
ALA D 102
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ALA B 152
SER B 151
ALA B 102
SER A  54
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
GLY H 101
ILE H 102
LEU E 387
SER H 103
GLY E 381
1.69A14.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL A  13
SER A  10
ALA A   7
SER A 113
1.80A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
VAL A 125
SER A  10
ALA A 116
SER A 123
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
SER A 254
ILE A 259
ALA A 260
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 147
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.27A
None
PEG  A 404 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 121
SER A 147
ALA A 116
SER A 123
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 147
ALA A 116
SER A 123
SER A 121
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.60A
None
None
None
None
EDO  D 205 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.42A
None
None
None
None
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL E 142
SER E 139
ALA E 112
SER E 128
1.56A
None
None
None
EPE  E 202 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.53A10.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ALA B  70
SER C   7
SER C   5
SER E 166
1.36A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL D 142
SER D 139
ALA D 112
SER D 128
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 129
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.56A
None
None
None
EDO  A 202 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL C 142
SER C 139
ALA C 112
SER C 128
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER E 166
ALA B  70
SER C   7
SER C   5
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.45A
None
None
None
None
EDO  C 208 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA B  38
ALA B 124
SER B 139
ALA B 129
1.45A
APR  B 201 (-3.4A)
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   7
ALA B  70
SER C   5
SER E 166
1.77A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA A 129
SER A 128
ALA A  38
ALA A 124
SER A 139
1.64A
APR  A 201 ( 3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA E 124
SER E 139
ALA E 129
SER E 128
ALA E  38
1.65A
None
None
APR  E 201 (-3.5A)
APR  E 201 (-4.4A)
APR  E 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA E  38
ALA E 124
SER E 139
ALA E 129
SER E 128
1.65A
APR  E 201 (-3.3A)
None
None
APR  E 201 (-3.5A)
APR  E 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL D 142
SER D 139
ALA D 112
SER D 128
1.55A
None
None
None
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER D 139
ALA D 129
ALA D  38
ALA D 124
1.42A
None
APR  D 201 (-3.4A)
APR  D 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA A 124
SER A 139
ALA A 129
SER A 128
ALA A  38
1.64A
None
None
APR  A 201 ( 3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA A  38
ALA A 124
SER A 139
ALA A 129
SER A 128
1.64A
APR  A 201 (-3.4A)
None
None
APR  A 201 ( 3.7A)
APR  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
ALA B  70
SER C   7
SER C   5
SER E 166
1.45A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.57A
None
None
None
APR  B 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL E 142
SER E 139
ALA E 112
SER E 128
1.53A
None
None
None
APR  E 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA D 124
SER D 139
ALA D 129
ALA D  38
1.42A
None
None
APR  D 201 (-3.4A)
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C 124
SER C 139
ALA C 129
ALA C  38
1.45A
None
None
APR  C 201 (-3.6A)
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.48A
None
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA B 124
SER B 139
ALA B 129
ALA B  38
1.45A
None
None
APR  B 201 (-3.6A)
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.42A
None
None
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 129
1.48A
None
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.49A
None
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.59A10.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C  38
ALA C 124
SER C 139
ALA C 129
1.45A
APR  C 201 (-3.4A)
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C 129
ALA C  38
ALA C 124
SER C 139
1.45A
APR  C 201 (-3.6A)
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA B 129
ALA B  38
ALA B 124
SER B 139
1.45A
APR  B 201 (-3.6A)
APR  B 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.47A
None
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER B 139
ALA B 129
ALA B  38
ALA B 124
1.45A
None
APR  B 201 (-3.6A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL C 142
SER C 139
ALA C 112
SER C 128
1.55A
None
None
None
APR  C 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
SER E 139
ALA E 129
SER E 128
ALA E  38
ALA E 124
1.65A
None
APR  E 201 (-3.5A)
APR  E 201 (-4.4A)
APR  E 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER C 139
ALA C 129
ALA C  38
ALA C 124
1.45A
None
APR  C 201 (-3.6A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER E 166
ALA B  70
SER C   7
SER C   5
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.48A
None
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.54A
None
None
None
APR  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
SER A 139
ALA A 129
SER A 128
ALA A  38
ALA A 124
1.64A
None
APR  A 201 ( 3.7A)
APR  A 201 (-4.4A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA D  38
ALA D 124
SER D 139
ALA D 129
1.42A
APR  D 201 (-3.3A)
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 8
ALA E 129
SER E 128
ALA E  38
ALA E 124
SER E 139
1.65A
APR  E 201 (-3.5A)
APR  E 201 (-4.4A)
APR  E 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA D 129
ALA D  38
ALA D 124
SER D 139
1.42A
APR  D 201 (-3.4A)
APR  D 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA A  38
ALA A 124
SER A 139
ALA A 129
1.44A
MES  A 201 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER C 139
ALA C 129
ALA C  38
ALA C 124
1.45A
None
None
MES  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.41A
EDO  C 203 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL C 142
SER C 139
ALA C 112
SER C 128
1.57A
None
None
None
MES  C 201 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL A 142
SER A 139
ALA A 112
SER A 128
1.54A
None
None
None
MES  A 201 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
SER A 139
ALA A 129
ALA A  38
ALA A 124
1.44A
None
None
MES  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
VAL B 142
SER B 139
ALA B 112
SER B 128
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.54A
None
None
EDO  A 206 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C 124
SER C 139
ALA C 129
ALA C  38
1.45A
None
None
None
MES  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA A 124
SER A 139
ALA A 129
ALA A  38
1.44A
None
None
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.45A
None
None
EDO  A 206 (-4.6A)
None
EDO  A 205 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C  38
ALA C 124
SER C 139
ALA C 129
1.45A
MES  C 201 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.53A
EDO  C 203 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA C 129
ALA C  38
ALA C 124
SER C 139
1.45A
None
MES  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.40A
None
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ALA A 129
ALA A  38
ALA A 124
SER A 139
1.44A
None
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.74A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 116
SER A 123
SER A 147
SER A 121
1.80A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ALA A 399
SER A 397
ALA B 150
ALA B 125
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		7btf NSP8
(SARS-CoV-2)		5 / 9
ILE B 156
SER B 170
LEU B 180
SER B 173
LEU B 184
1.80A9.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
VAL A 662
ALA A 558
SER A 681
SER A 561
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
VAL A 609
SER A 607
SER A 754
ALA A 747
1.79A2.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7btf NSP12
NSP7
(SARS-CoV-2)		4 / 6
VAL C  11
SER C  15
SER C  10
ALA A 443
1.50A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 502
SER A 561
ALA A 512
SER A 564
1.73A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
VAL A 560
SER A 564
SER A 561
ALA A 660
1.67A2.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 706
SER A 784
1.60A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ALA B 125
ALA A 399
SER A 397
ALA B 150
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 702
SER A 784
1.64A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		5 / 9
SER A 772
GLY A 774
SER A 768
LEU A 775
SER A 778
1.64A2.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 777
SER A 784
1.49A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 6
LEU A 638
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ALA B 150
ALA B 125
ALA A 399
SER A 397
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7btf NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 702
SER A 784
1.32A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
SER A 147
ALA A 116
SER A 123
SER A 121
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
SER A 121
SER A 147
ALA A 116
SER A 123
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.58A6.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ALA A 116
SER A 123
SER A 147
SER A 121
1.66A6.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ALA A 116
SER A 123
SER A 121
SER A 147
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
VAL A 125
SER A  10
ALA A 116
SER A 123
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
LEU C  17
LEU C  55
SER C  57
ILE D 119
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
VAL C  53
SER C  54
ALA D 150
SER D 151
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
SER A 772
GLY A 774
SER A 768
LEU A 775
SER A 778
1.71A2.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 102
SER C  54
ALA D 152
SER D 151
0.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 702
SER A 784
1.69A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 502
SER A 561
ALA A 512
SER A 564
1.70A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
ALA D 150
SER D 151
ALA D 152
SER C  54
1.63A9.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ALA A 634
SER A 635
ALA A 688
SER A 759
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 778
ALA A 777
SER A 784
1.49A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  54
ALA D 152
SER D 151
ALA D 102
0.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 399
SER A 397
SER A 672
ALA A 400
1.77A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ALA A 688
SER A 759
ALA A 634
SER A 635
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 102
SER C  57
ALA D 152
SER D 151
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
VAL C  53
SER C  54
ALA D 152
SER D 151
1.39A15.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 152
SER D 151
ALA D 102
SER C  57
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ALA D 152
SER D 151
ALA D 102
SER C  54
0.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
VAL A 662
SER A 681
ALA A 690
SER A 635
1.61A2.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 6
LEU A 638
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 702
SER A 784
1.36A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER C  57
ALA D 152
SER D 151
ALA D 102
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 527
LEU A 372
SER A 561
ILE A 562
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 6
LEU A 638
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.70A
None
None
None
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 706
SER A 784
1.65A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 777
SER A 784
1.51A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B  98
LEU B 103
ILE B 120
ALA A 379
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 777
SER A 778
ALA A 702
SER A 784
1.68A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		7bv2 NSP8
(SARS-CoV-2)		5 / 9
ILE B 156
SER B 170
LEU B 180
SER B 173
LEU B 184
1.66A9.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
VAL A 662
ALA A 558
SER A 681
SER A 561
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 778
ALA A 777
SER A 784
1.46A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 502
SER A 561
ALA A 512
SER A 564
1.73A2.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ALA A 706
SER A 709
ALA A 702
SER A 784
1.35A2.57
None