Ligand ID: 1GN


Drugbank ID:
DB01296
(Glucosamine)


Indication:
Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question.

Get human targets for 1GN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '1GN' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
VAL D 296
GLU D 290
GLU D 288
1.49A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
VAL D 114
GLU D 288
GLU D 290
1.35A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
1.02A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
1.03A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
THR A  95
SER A  94
TYR A 266
0.93A20.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
THR A  95
SER A  94
TYR A 266
0.95A20.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
VAL C 551
GLU C 583
GLU C 554
1.41A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w4h NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A16.36
ACT  A7103 ( 4.6A)
ACT  A7104 ( 4.8A)
ACT  A7103 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w4h NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A16.36
ACT  A7103 ( 4.6A)
ACT  A7104 ( 4.8A)
ACT  A7103 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
KCX  A6935 (-3.2A)
EDO  A7102 ( 4.7A)
KCX  A6935 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.44A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.46A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.45A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.47A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.55A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.53A13.46
FMT  A7103 ( 3.0A)
None
FMT  A7103 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.46A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.46A13.46
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
FMT  C7111 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6w75 NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A13.46
FMT  C7107 ( 3.0A)
None
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
THR C 301
SER C 262
TYR C 273
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 (-3.0A)
None
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7103 (-3.1A)
None
FMT  A7103 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.46A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.45A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.44A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.46A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.44A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.53A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6833
SER C7039
TYR C7040
1.45A
FMT  C7111 ( 3.7A)
FMT  C7111 ( 3.1A)
FMT  C7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR C6970
SER C6973
TYR C6930
1.54A
FMT  C7104 ( 3.0A)
None
FMT  C7104 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wkq NSP16
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.54A
FMT  A7105 ( 3.0A)
None
FMT  A7105 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.56A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
THR A6970
SER A6973
TYR A6930
1.55A
GTA  A7102 (-3.4A)
None
GTA  A7102 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6xdc PROTEIN 3A
(SARS-CoV-2)		3 / 3
THR A 164
SER A 166
TYR A 212
1.27A18.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
VAL A 296
GLU A 290
GLU A 288
1.61A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
VAL A 114
GLU A 288
GLU A 290
1.40A13.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
THR E 385
SER H 100
TYR H  32
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL A  95
GLU D 114
GLU A 114
1.79A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL D  95
GLU A 114
GLU D 114
1.79A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL D  95
GLU A 114
GLU D 114
1.75A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL A  95
GLU D 114
GLU A 114
1.74A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL A  95
GLU C 114
GLU A 114
1.77A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
VAL C  95
GLU A 114
GLU C 114
1.77A12.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		6zsl SARS-COV-2 HELICASE
NSP13
(SARS-CoV-2)		3 / 3
THR A 550
SER A 555
TYR A 515
1.37A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.93A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.93A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
VAL A 353
GLU A 278
GLU A 277
1.79A23.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.97A23.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.98A23.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.84A23.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 788
TYR A 732
GLN A 468
0.84A23.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
THR A 252
SER A 255
TYR A 265
1.20A
None