Ligand ID: Y00


Drugbank ID:
DB00841
(Dobutamine)


Indication:
For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures

Get human targets for Y00 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'Y00' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
GLY B 109
LEU B 202
PHE B 294
PHE B   8
1.30A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL A 933
ASP F 932
SER D1156
ASN F 937
VAL F1157
1.73A14.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		1wnc E2 GLYCOPROTEIN
(SARSr)		5 / 12
ASP F 932
VAL F 933
SER D1156
VAL B 945
ASN B 942
1.20A14.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
LEU H 133
VAL H 135
TRP H 159
ASN H 105
ASN H 110
1.69A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
VAL F 172
TRP F 187
ASP F 139
ASN F 114
VAL F 191
1.68A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ASP A 153
PHE A 294
PHE A   8
PHE A 305
ASN A 151
1.64A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.58A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.60A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.57A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
VAL E 271
TRP E 302
PHE E 308
ASN E 355
TYR E 299
1.64A14.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
VAL S 389
THR S 487
VAL H  97
ASN S 427
ASN S 424
1.15A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR H 160
VAL H 163
SER H 180
ASN H 197
TYR H 194
1.55A21.25
None
None
None
PO4  H 501 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_2
(BETA-1 ADRENERGIC
RECEPTOR)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 4
VAL H  20
PHE H  29
VAL H 102
TRP H 103
1.71A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
VAL E 382
PHE E 364
PHE E 329
PHE E 325
1.30A20.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2ghw SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU A 503
VAL A 498
SER A 386
PHE A 329
TYR A 352
1.73A16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		3 / 3
VAL A  52
ASN A 101
TRP A  87
1.26A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU B 263
VAL B 275
PHE B 240
PHE B 329
1.31A22.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
THR B 304
VAL B 303
SER A 121
SER A 123
ASN A  28
1.75A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A  75
VAL A  91
SER A  10
PHE A 159
PHE A 150
1.67A20.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
VAL B 101
SER A 288
ASN B 163
VAL B  84
ASN B  62
1.31A21.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2xyq NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
VAL B  42
ASP A 130
SER A 175
ASN A  43
TYR A  47
1.63A17.23
None
SAH  A1293 (-3.7A)
None
SAH  A1293 (-3.8A)
SAH  A1293 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
VAL A  78
ASP A 130
SER A 201
ASN A  43
TYR A  47
1.76A25.00
None
SAH  A1293 (-3.7A)
None
SAH  A1293 (-3.8A)
SAH  A1293 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
VAL A  78
ASP A 130
SER A 201
ASN A  43
TYR A  47
1.76A24.93
None
SFG  A1298 (-3.6A)
None
SFG  A1298 (-3.5A)
SFG  A1298 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2xyv NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
VAL B  42
ASP A 130
SER A 175
ASN A  43
TYR A  47
1.72A17.57
None
SAH  A1300 (-3.7A)
None
SAH  A1300 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		2z9l 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.51A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		3bgf F26G19 FAB
(Mus
musculus)		5 / 12
VAL C 133
SER C 176
SER B 180
ASN C 137
VAL B 138
1.77A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.27A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.26A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.27A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
VAL A 404
ASP A 350
SER A  44
SER A  40
TYR A 385
1.70A19.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.57A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.59A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.61A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3i6k BETA-2-MICROGLOBULIN
HLA, A-2
MEMBRANE
GLYCOPROTEIN PEPTIDE
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL A  12
PHE B  56
PHE B  62
TYR A 116
1.66A3.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3i6k BETA-2-MICROGLOBULIN
HLA, A-2
MEMBRANE
GLYCOPROTEIN PEPTIDE
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL A  12
PHE B  56
PHE B  62
TYR A 116
1.66A3.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3i6k BETA-2-MICROGLOBULIN
HLA, A-2
MEMBRANE
GLYCOPROTEIN PEPTIDE
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL A  12
PHE B  56
PHE B  62
TYR A 116
1.64A3.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.62A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
VAL B 125
SER A 113
SER A  10
PHE A 305
1.64A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A  75
VAL A  91
SER A  10
PHE A 159
PHE A 150
1.68A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3scj ACE2
(Homo
sapiens)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.31A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3scj ACE2
(Homo
sapiens)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.31A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3scj ACE2
(Homo
sapiens)		5 / 12
LEU A 248
VAL A 244
ASP A 269
SER A 502
PHE A 452
1.30A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.28A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.27A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.27A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
VAL B 404
ASP B 350
SER B  43
SER B  40
TYR B 385
1.60A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3to2 MD3-C9 PEPTIDE
DERIVED FROM
MEMBRANE
GLYCOPROTEIN
MHC CLASS I ANTIGEN
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL C   5
VAL A  25
PHE A  33
TYR A  99
1.62A3.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3to2 BETA-2-MICROGLOBULIN
MD3-C9 PEPTIDE
DERIVED FROM
MEMBRANE
GLYCOPROTEIN
MHC CLASS I ANTIGEN
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL A  12
SER B  33
PHE B  56
TYR A 116
1.56A3.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3to2 BETA-2-MICROGLOBULIN
MD3-C9 PEPTIDE
DERIVED FROM
MEMBRANE
GLYCOPROTEIN
MHC CLASS I ANTIGEN
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
LEU C   6
VAL A  12
SER B  33
PHE B  56
TYR A 116
1.61A3.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3vb3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 141
VAL A 125
SER B 113
SER B  10
PHE B 305
1.53A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		3vb3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 141
VAL A 125
SER B 113
SER B  10
PHE B 305
1.54A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
VAL A 255
PHE A 292
ASN A 114
VAL A 268
ASN A 267
1.46A22.07
PO4  A 404 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
VAL D 182
VAL D  66
SER C  33
ASN D  63
ASN D  71
1.70A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
VAL D 162
VAL D 125
ASN D 137
VAL D 120
TRP D 159
1.62A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
VAL B 389
THR B 403
VAL B 405
SER B 407
PHE B 506
1.66A20.52
SAM  B 605 ( 4.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
VAL D 162
VAL D 125
ASN D 137
VAL D 120
TRP D 159
1.50A20.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5f22 NSP8
(SARSr-CoV)		5 / 12
LEU B 133
VAL B 135
TRP B 159
ASN B 105
ASN B 110
1.71A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
VAL B 162
VAL B 125
ASN B 137
VAL B 120
TRP B 159
1.58A20.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
VAL D 389
THR D 403
VAL D 405
SER D 407
PHE D 506
1.64A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU A 735
VAL A 958
SER C 556
PHE A 837
ASN A 838
1.67A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A  64
SER A  35
PHE A 262
PHE A  62
TYR A  41
1.63A24.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A  64
SER A  35
PHE A 262
PHE A  62
TYR A  41
1.60A24.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A  64
SER A  35
PHE A 262
PHE A  62
TYR A  41
1.64A24.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
GLY C1026
PHE C1034
PHE C 909
PHE C 782
1.09A13.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
LEU B 944
VAL B 945
SER A 582
PHE A 305
ASN A 304
1.54A13.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
LEU B 944
VAL B 945
SER A 582
PHE A 305
ASN A 304
1.45A13.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
PHE C 185
PHE C 168
ASN C 118
VAL C  97
ASN C  96
1.79A13.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
LEU B 944
VAL B 945
SER A 582
PHE A 305
ASN A 304
1.55A13.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
VAL A 518
THR B 259
SER A 439
SER A 440
ASN A 475
1.67A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL C 307
THR C 302
VAL C 583
ASN C 281
TYR C 598
1.51A13.34
VAL  C 307 ( 0.6A)
THR  C 302 ( 0.8A)
VAL  C 583 ( 0.6A)
ASN  C 281 ( 0.6A)
TYR  C 598 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
GLY B1026
PHE B1034
PHE B 909
PHE B 782
1.10A12.13
GLY  B1026 ( 0.0A)
PHE  B1034 ( 1.3A)
PHE  B 909 ( 1.3A)
PHE  B 782 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL A 808
PHE A 815
ASN A 942
VAL A 934
ASN A 935
1.47A13.34
VAL  A 808 ( 0.6A)
PHE  A 815 ( 1.3A)
ASN  A 942 ( 0.6A)
VAL  A 934 ( 0.6A)
ASN  A 935 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL C 307
THR C 302
VAL C 583
ASN C 281
TYR C 598
1.50A13.34
VAL  C 307 ( 0.6A)
THR  C 302 ( 0.8A)
VAL  C 583 ( 0.6A)
ASN  C 281 ( 0.6A)
TYR  C 598 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		5 / 12
VAL a  13
PHE c  15
ASN C 935
VAL A 934
ASN A 937
1.67A11.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A  64
SER A  35
PHE A 262
PHE A  62
TYR A  41
1.48A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE B 185
PHE B 168
ASN B 118
VAL B  97
ASN B  96
1.64A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU B 538
VAL B 537
THR B 559
SER A 956
SER A 957
1.26A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU B 538
VAL B 537
THR B 559
SER A 956
SER A 957
1.29A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASP B 376
SER A 728
ASN B 526
VAL B 314
ASN B 528
1.52A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
GLY C 928
LEU C 927
PHE C1044
PHE C1024
1.00A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ASP C 727
PHE B 578
PHE C 837
PHE B 558
VAL B 537
1.75A12.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
GLY C1026
PHE C1034
PHE C 909
PHE C 782
1.28A13.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE C  76
PHE C  22
ASN C 135
ASN C  78
TYR C 252
1.69A12.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
GLY C1026
PHE C1034
PHE C 909
PHE C 782
1.10A12.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL A 496
VAL A 510
SER A 380
VAL A 498
TYR A 352
1.71A12.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6cs2 ACE2
(Homo
sapiens)		5 / 12
LEU D 248
VAL D 244
ASP D 269
SER D 502
PHE D 452
1.36A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B  64
SER B  35
PHE B 262
PHE B  62
TYR B  41
1.42A12.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL C 307
THR C 302
VAL C 583
ASN C 281
TYR C 598
1.32A12.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL C 307
THR C 302
VAL C 583
ASN C 281
TYR C 598
1.33A12.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6jyt HELICASE
(SARSr-CoV)		5 / 12
LEU A  41
ASP A  56
VAL B  45
SER B  13
PHE B  24
1.62A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6jyt HELICASE
(SARSr-CoV)		5 / 12
LEU A  41
ASP A  56
VAL B  45
SER B  13
PHE B  24
1.63A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
VAL C 324
THR C 313
VAL C  50
SER C 227
SER C 430
1.56A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
GLY C  82
LEU C  85
PHE C 283
PHE C  48
1.05A19.15
None
None
LEU  C 707 (-3.8A)
LEU  C 707 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6m1d ACE2
SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
GLY B 747
LEU B 743
VAL A 207
PHE A 425
1.29A15.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
GLY B1026
PHE B1034
PHE B 909
PHE B 782
1.22A13.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H 221
THR H 179
VAL H 195
SER L 181
VAL H 135
1.63A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nur NSP12
(SARSr-CoV)		5 / 12
LEU A 673
VAL A 398
ASP A 377
VAL A 373
ASN A 657
1.35A14.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nur NSP12
(SARSr)		4 / 6
GLY A 678
LEU A 663
VAL A 792
PHE A 694
0.90A14.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nur NSP12
(SARSr-CoV)		5 / 12
LEU A 673
VAL A 398
ASP A 377
VAL A 373
ASN A 657
1.38A14.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nur NSP12
(SARSr-CoV)		5 / 12
LEU A 673
VAL A 398
ASP A 377
VAL A 373
ASN A 657
1.37A14.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6nur NSP12
(SARSr-CoV)		5 / 12
VAL A 354
ASP A 358
SER A 367
VAL A 535
ASN A 534
1.72A14.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6nus NSP12
(SARSr-CoV)		5 / 12
VAL A 398
THR A 538
ASP A 377
VAL A 373
ASN A 356
1.69A14.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6vw1 ACE2
(Homo
sapiens)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.27A18.73
None
None
None
CL  B 704 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6vw1 ACE2
(Homo
sapiens)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.27A18.73
None
None
None
CL  B 704 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		6vw1 ACE2
(Homo
sapiens)		5 / 12
LEU B 248
VAL B 244
ASP B 269
SER B 502
PHE B 452
1.26A18.73
None
None
None
CL  B 704 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
GLY H 139
LEU H 124
VAL H 207
PHE H 122
1.54A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
GLY H 139
LEU H 124
VAL H 207
PHE H 122
1.55A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
GLY B 143
LEU B 128
VAL B 211
PHE B 126
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
THR B 139
SER C 120
ASN C 144
VAL B 167
TRP B 158
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL B 211
THR B 169
VAL B 185
SER C 182
VAL B 125
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
THR H 139
SER L 120
ASN L 144
VAL H 167
TRP H 158
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL B 211
THR B 169
VAL B 185
SER C 182
VAL B 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR B 164
VAL B 167
SER B 184
ASN B 201
ASN B 159
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR B 164
VAL B 167
SER B 184
ASN B 201
ASN B 159
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
VAL H 125
TRP H 158
VAL H 188
SER H 190
SER H 192
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
GLY B 143
LEU B 128
VAL B 211
PHE B 126
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
THR B 139
SER C 120
ASN C 144
VAL B 167
TRP B 158
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
THR H 139
SER L 120
ASN L 144
VAL H 167
TRP H 158
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
GLY H 143
LEU H 128
VAL H 211
PHE H 126
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
GLY H 143
LEU H 128
VAL H 211
PHE H 126
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
VAL H 125
TRP H 158
VAL H 188
SER H 190
SER H 192
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
VAL H 125
TRP H 158
VAL H 188
SER H 190
SER H 192
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
THR B 139
SER C 120
ASN C 144
VAL B 167
TRP B 158
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
VAL B 211
THR B 169
VAL B 185
SER C 182
VAL B 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
THR H 139
SER L 120
ASN L 144
VAL H 167
TRP H 158
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
VAL B 211
THR B 169
VAL B 185
SER C 182
VAL B 125
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
VAL H 211
THR H 169
VAL H 185
SER L 182
VAL H 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
VAL B 125
TRP B 158
VAL B 188
SER B 190
SER B 192
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
THR B 164
VAL B 167
SER B 184
ASN B 201
ASN B 159
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
THR B 164
VAL B 167
SER B 184
ASN B 201
ASN B 159
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
THR H 139
SER L 120
ASN L 144
VAL H 167
TRP H 158
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
THR B 139
SER C 120
ASN C 144
VAL B 167
TRP B 158
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
VAL H 125
TRP H 158
VAL H 188
SER H 190
SER H 192
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
THR H 164
VAL H 167
SER H 184
ASN H 201
ASN H 159
1.61A
None