Ligand ID: SNP


Drugbank ID:
DB00571
(Propranolol)


Indication:
For the prophylaxis of migraine.

Get human targets for SNP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'SNP' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN A 127
PHE A 140
GLY A 138
VAL A 171
0.75A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		1wnc E2 GLYCOPROTEIN
(SARSr)		4 / 7
ILE E 913
ILE F 913
PHE E 909
LEU F 920
1.44A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 7
ILE B 913
ILE C 916
SER C1177
PHE B 909
LEU C 920
1.68A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ALA B 912
ILE B 916
ILE A 916
ILE C 916
PHE C 909
1.46A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
ILE A 281
LEU A 282
ALA A 211
ILE A 213
PHE A 219
1.50A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE B1200
ILE B1106
THR B1135
ILE B1136
0.97A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN B1306
GLY A  11
GLY A  15
VAL A  13
1.32A20.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ALA K   6
ILE I   5
ILE K   5
ILE L  31
SER L  29
1.52A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 7
GLN B 127
PHE B 140
GLY B 138
VAL B 171
1.01A20.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 7
ILE B  43
ILE B  59
SER B  65
PHE B  66
1.07A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 7
GLN B 320
GLY B 260
SER B 310
GLY B 279
VAL B 259
1.43A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 7
ILE F 171
ILE F 177
THR F 192
ILE F 161
LEU F 189
1.69A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
ILE A  43
ILE A  59
SER A  65
PHE A  66
1.06A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE B  43
ILE B  59
SER B  65
PHE B  66
1.02A21.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 7
ILE G 305
ILE G 293
THR G 264
SER H 313
PHE H 316
1.66A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 5
PHE A 159
VAL B 125
PRO A 122
VAL A 148
1.65A22.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 5
PHE H 122
VAL H 169
PRO H 119
VAL H 121
1.66A21.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 7
GLN B 139
GLY B  79
SER B 129
GLY B  98
VAL B  78
1.46A19.44
None
None
APR  B 477 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 5
PHE C 242
VAL C 301
MET C 170
VAL C 206
1.37A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 7
ILE A  84
THR A  92
ILE A  91
SER A  89
1.25A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 7
ASP C 480
GLY D 198
PHE D 203
SER D 163
1.33A18.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 7
ILE D 190
THR D 206
ILE D 207
SER D 208
LEU D 179
1.80A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		2gri NSP3
(SARSr-CoV)		4 / 5
PHE A  54
VAL A  62
MET A 103
VAL A  51
1.51A15.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 7
ILE D 305
ILE D 327
THR D 195
ILE D 295
PHE D 302
1.69A23.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 8
ILE A 295
LEU A 250
ILE A 235
ILE A 306
PHE A 329
1.36A23.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 7
ILE B  43
ILE B  59
SER B  65
PHE B  66
1.05A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 7
ILE B  43
ILE B  59
SER B  65
PHE B  66
0.94A19.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
ILE A  43
ILE A  59
SER A  65
PHE A  66
1.00A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 7
GLN B 159
GLY A 286
GLY B 169
VAL B 172
0.87A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 7
ILE A  71
ILE A 295
THR A 321
ILE A 327
LEU A 297
1.63A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 5
PHE B  55
VAL D   5
PRO B  23
VAL B  31
1.72A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 8
ILE A 171
LEU A 206
ILE A 167
ILE A 157
PHE A 150
1.44A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 7
ILE A 157
ILE A 128
ILE A 207
PHE A 187
1.06A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 8
ILE A 171
LEU A 206
ILE A 167
ILE A 157
PHE A 150
1.44A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		2zu4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE A  43
ILE A  59
SER A  65
PHE A  66
0.91A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		3aw0 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE A  43
ILE A  59
SER A  65
PHE A  66
0.97A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
TYR B 207
SER B 511
GLU B 398
ASP B 206
ASP B 201
1.79A19.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		3e9s NSP3
(SARSr-CoV)		4 / 5
PHE A 242
VAL A 301
MET A 170
VAL A 206
1.39A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN B 127
PHE B 140
GLY B 138
VAL B 171
1.19A20.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN A 127
PHE A 140
GLY A 138
VAL A 171
0.96A20.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		3i6g HLA, A-2
(Homo
sapiens)		5 / 12
TYR D   7
GLU D  63
GLU D  55
THR D 163
ARG A 157
1.72A18.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		4 / 5
PHE F   2
VAL D 152
MET D  97
VAL D  67
1.75A8.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		3i6l HLA, A-24
(Homo
sapiens)		4 / 5
HIS D  70
TRP D 147
TYR D 118
ALA D  81
1.51A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		5 / 12
TYR D   7
GLN F   1
GLU D  63
GLU D  55
THR D 163
1.67A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN B 127
PHE B 140
GLY B 138
VAL B 171
1.13A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE B 200
ILE B 106
THR B 135
ILE B 136
1.05A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN A 127
PHE A 140
GLY A 138
VAL A 171
1.25A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 8
ILE A 171
LEU A 206
ILE A 167
ILE A 157
PHE A 150
1.47A19.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
TYR E 436
TYR E 484
GLN A  37
GLU A  38
ASP E 393
1.69A17.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
TYR B 207
SER B 511
GLU B 398
ASP B 206
ASP B 201
1.77A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE A  43
ILE A  59
SER A  65
PHE A  66
1.03A21.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
ILE B 200
ILE B 106
THR B 135
ILE B 136
1.04A21.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 5
PHE A 242
VAL A 301
MET A 170
VAL A 206
1.43A20.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		4m0w UBIQUITIN
(Bos
taurus)		5 / 7
ILE B  30
ILE B  23
THR B  66
ILE B   3
LEU B  50
1.36A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		4 / 5
PHE B 242
VAL B 301
MET B 170
VAL B 206
1.33A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 7
ILE A 126
ILE A 152
THR A 119
ILE A 117
LEU A 169
1.75A21.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5c5o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
GLN B 127
PHE B 140
GLY B 138
VAL B 171
1.02A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
ASP D 243
GLN D 245
GLY D  59
GLY D 189
1.11A20.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
ASP D 243
GLN D 245
GLY D  59
GLY D 189
1.17A20.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 5
PHE D 242
VAL D 301
MET D 170
VAL D 206
1.43A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
ASP B 243
GLN B 245
GLY B  59
GLY B 189
1.24A20.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 5
PHE B 242
VAL B 301
MET B 170
VAL B 206
1.44A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 8
ILE B 656
LEU B 636
ALA B 676
ILE B 674
ILE B 650
1.43A10.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		5x59 S PROTEIN
(MERS-CoV)		4 / 7
ILE C 782
ILE C 985
ILE C1165
PHE C1172
0.93A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5x59 S PROTEIN
(MERS-CoV)		4 / 5
PHE B1172
VAL C 958
PRO B 783
VAL B1149
1.77A13.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA C 954
TYR B 367
SER B 370
GLU C 970
ASP C 961
1.78A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 7
ASP C  50
PHE C  47
SER C  49
GLY C 270
1.30A13.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 5
PHE A 888
VAL A1022
PRO A1051
VAL A 893
1.52A13.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5x5f S PROTEIN
(MERS-CoV)		4 / 7
GLY C 601
SER C 371
GLY C 372
VAL C 374
1.18A13.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
GLN A 632
GLY C 839
PHE A 578
GLY A 579
1.24A14.12
GLN  A 632 ( 0.6A)
GLY  C 839 ( 0.0A)
PHE  A 578 ( 1.3A)
GLY  A 579 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ILE B 234
LEU B 235
ILE B 117
ILE B 116
PHE B  89
1.46A13.40
ILE  B 234 ( 0.7A)
LEU  B 235 ( 0.5A)
ILE  B 117 ( 0.7A)
ILE  B 116 ( 0.6A)
PHE  B  89 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
PHE C 888
VAL C1022
PRO C1051
VAL C 893
1.60A14.12
PHE  C 888 ( 1.3A)
VAL  C1022 ( 0.6A)
PRO  C1051 ( 1.1A)
VAL  C 893 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 5
PHE A 242
VAL A 301
MET A 170
VAL A 206
1.39A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		5 / 8
ILE B 913
LEU b  32
ALA C 912
ILE C 913
PHE B 909
1.43A22.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
PHE C  76
VAL C 254
PRO C  79
VAL C  25
1.62A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 7
ILE B 621
THR B 624
ILE B 637
SER B 623
LEU B 615
1.57A13.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		6acj ACE2
(Homo
sapiens)		4 / 5
HIS D 241
TYR D 613
ALA D 614
TRP D 610
1.44A19.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 885
SER A1093
GLN A1088
GLU B1074
ARG A1073
1.69A17.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ILE A 656
LEU A 636
ALA A 676
ILE A 674
ILE A 650
1.39A13.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
ASP C  50
PHE C  47
SER C  49
GLY C 270
1.29A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
ASP B  50
PHE B  47
SER B  49
GLY B 270
1.24A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 8
ILE A 226
LEU A 224
ALA A 127
ILE A 125
ILE A 115
1.51A10.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 8
ILE A 637
LEU A 597
ALA A 595
ILE A 584
ILE A 674
1.33A10.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 7
ILE A 913
ILE A 800
THR A 705
PHE A 909
LEU A 920
1.74A10.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
PHE B 888
VAL B1022
PRO B1051
VAL B 893
1.36A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6cs2 ACE2
(Homo
sapiens)		4 / 5
VAL D 404
PRO D 321
MET D 323
VAL D 316
1.61A18.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
ASP B  50
PHE B  47
SER B  49
GLY B 270
1.15A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		6lzg ACE2
(Homo
sapiens)		5 / 12
TYR A 207
SER A 511
GLU A 398
ASP A 206
ASP A 201
1.80A19.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6m17 ACE2
(Homo
sapiens)		4 / 5
VAL B 404
PRO B 321
MET B 323
VAL B 316
1.54A16.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 7
ASP C 486
GLY C 397
GLY C 395
VAL C 393
1.04A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 7
ILE A 325
ILE A 319
THR A 248
ILE A 251
LEU A 238
1.75A16.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ILE B 656
LEU B 636
ALA B 676
ILE B 674
ILE B 650
1.45A13.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6nur NSP8
(SARSr-CoV)		5 / 7
ILE B 166
ILE B 172
THR B 187
ILE B 156
LEU B 184
1.66A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		6nus NSP12
(SARSr-CoV)		4 / 7
ASP A 377
SER A 343
GLY A 345
VAL A 354
1.29A17.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6vw1 ACE2
(Homo
sapiens)		4 / 5
PHE B 525
VAL B 209
MET B 557
VAL B 574
1.60A18.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
ILE H  34
ALA H  71
ILE H  75
PHE H  29
1.12A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
ALA H  78
ILE H  34
ILE H  51
ILE H  69
1.24A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
ILE H  20
ILE H  34
ILE H  51
SER H  70
1.65A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  20
THR H  68
SER H  70
LEU H  18
1.29A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 5
PHE H 122
VAL H 169
PRO H 119
VAL H 121
1.69A19.94
None
GOL  L 301 (-4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
ILE H  20
ILE H  34
ILE H  51
ILE H  69
1.52A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
ILE H  34
ALA H  78
ILE H  75
PHE H  29
1.65A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  98
ILE H  34
THR H  57
ILE H  69
1.63A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 5
PHE L  98
VAL L  27
PRO H 100
MET H 100
1.54A20.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ILE L 117
ALA L 193
SER L 215
PHE L 209
1.64A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
ILE L  75
ILE L 106
PHE L  62
LEU L  15
1.60A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ALA H  93
ILE H  34
ILE H  50
PHE L  98
1.45A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  20
ILE H  69
THR H  77
ILE H  34
1.56A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ILE L  48
LEU L  47
ILE L  75
ILE L  21
1.32A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
THR L  74
ILE L  75
SER L  76
LEU L  47
1.44A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
PHE B 126
VAL B 173
PRO B 123
VAL B 125
1.71A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  20
THR H  69
SER H  71
LEU H  18
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
ALA B  79
ILE B  34
ILE B  51
ILE B  70
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
PHE H 126
VAL H 173
PRO H 123
VAL H 125
1.73A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
PHE C 104
VAL C  29
PRO B 105
MET B 106
1.55A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
ILE C  54
LEU C  53
ILE C  81
ILE C  21
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
ALA H  79
ILE H  34
ILE H  51
ILE H  70
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
ILE L  54
LEU L  53
ILE L  81
ILE L  21
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
ILE B  34
ALA B  72
ILE B  76
PHE B  29
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
PHE L 104
VAL L  29
PRO H 105
MET H 106
1.43A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  20
THR B  69
SER B  71
LEU B  18
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR C  80
ILE C  81
SER C  82
LEU C  53
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
ILE H  34
ALA H  72
ILE H  76
PHE H  29
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR L  80
ILE L  81
SER L  82
LEU L  53
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR L  80
ILE L  81
SER L  82
LEU L  53
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  20
THR H  69
SER H  71
LEU H  18
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
ILE H  34
ALA H  72
ILE H  76
PHE H  29
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 5
PHE H 126
VAL H 173
PRO H 123
VAL H 125
1.79A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
ILE L  54
LEU L  53
ILE L  81
ILE L  21
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
PHE L 104
VAL L  29
PRO H 105
MET H 106
1.46A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
ALA H  79
ILE H  34
ILE H  51
ILE H  70
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
PHE B 126
VAL B 173
PRO B 123
VAL B 125
1.74A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 5
PHE C 104
VAL C  29
PRO B 105
MET B 106
1.43A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
THR L  80
ILE L  81
SER L  82
LEU L  53
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
ALA H  79
ILE H  34
ILE H  51
ILE H  70
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
PHE H 126
VAL H 173
PRO H 123
VAL H 125
1.73A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
ILE B  34
ALA B  72
ILE B  76
PHE B  29
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
ALA B  79
ILE B  34
ILE B  51
ILE B  70
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
ILE C  54
LEU C  53
ILE C  81
ILE C  21
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  20
THR H  69
SER H  71
LEU H  18
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
ILE H  34
ALA H  72
ILE H  76
PHE H  29
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 5
PHE L 104
VAL L  29
PRO H 105
MET H 106
1.43A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
THR C  80
ILE C  81
SER C  82
LEU C  53
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  20
THR B  69
SER B  71
LEU B  18
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_B_SNPB1236_1
(MROUPO)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
ILE L  54
LEU L  53
ILE L  81
ILE L  21
1.25A
None