Ligand ID: OAQ


Drugbank ID:
DB01096
(Oxamniquine)


Indication:
For treatment of Schistosomiasis caused by Schistosoma mansoni

Get human targets for OAQ in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'OAQ' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		6 / 12
ILE B 249
ILE B 200
LEU B 250
LEU B 242
THR B 201
LEU B 205
1.44A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
PRO B  39
ILE B 136
PHE B 140
SER B 147
LEU B 167
1.76A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO B  39
LEU B  27
PHE B 140
SER B 144
THR B 135
1.63A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 916
VAL B1170
LEU C 920
THR B 923
LEU C1167
1.61A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		1x7q BETA-2-MICROGLOBULIN
HLA, A-11
(Homo
sapiens)		5 / 12
LEU B  54
VAL A  12
ASP A 119
SER B  33
LEU A  81
1.39A17.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE I  16
VAL H  22
LEU K  20
THR I  23
LEU J  19
1.54A12.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2a5i 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
LEU A 242
THR A 201
1.32A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2a5i 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
THR A 201
LEU A 205
1.55A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		2a5i 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
ILE A 249
ILE A 200
PHE A 294
LEU A 242
THR A 201
1.39A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		7 / 12
ILE A 249
ILE A 200
LEU A 250
PHE A 294
LEU A 242
THR A 201
LEU A 205
1.58A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
ILE F 161
LEU F 133
VAL F 137
VAL F 135
LEU F 174
1.55A22.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 12
MET G  72
LEU H 122
VAL H 120
LEU D  60
LEU D  18
1.56A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2ajf ACE2
(Homo
sapiens)		5 / 12
PRO B 415
HIS B 417
VAL B 293
ASP B 367
MET B 297
1.41A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 916
VAL D1171
LEU C 920
THR B 923
LEU E1168
1.59A10.33
ACE  B 913 ( 3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 12
LEU A  13
VAL A  93
VAL A  94
LEU A  55
LEU B  22
1.37A17.70
None
None
None
D10  B1099 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 12
LEU H  13
VAL H  93
VAL H  94
LEU H  55
LEU G  22
1.34A16.54
None
None
None
D10  H1099 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 12
LEU E  13
VAL E  93
VAL E  94
LEU E  55
LEU F  22
1.36A17.70
None
None
None
D10  F1099 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 12
PRO H  40
ILE G  20
VAL H  42
LEU G  55
THR G  23
1.56A19.69
None
None
None
D10  H1099 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO B  39
HIS B 163
LEU B  27
THR B  25
THR B 190
1.62A21.23
None
ENB  B1145 (-3.7A)
ENB  B1145 (-4.2A)
ENB  B1145 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.40A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO L  15
ILE L  75
VAL L  13
LEU L  73
THR L 102
1.49A19.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		6 / 12
PRO H 126
LEU H 189
VAL H 182
VAL H 184
SER H 188
THR H 160
1.73A22.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.50A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_1
(SULFOTRANSFERASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
TYR A 440
ASP B 182
ASP A 392
SER B 101
1.77A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 12
ILE A 306
LEU A 299
VAL A 236
LEU A 331
THR A 340
1.62A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 12
PRO A  93
ILE A  79
LEU A  57
LEU A 119
THR A 105
1.57A21.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.40A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.48A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
PRO D  93
ILE D  79
LEU D  57
LEU D 119
THR D 105
1.48A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE B 235
LEU B 248
VAL B 318
PHE B 302
LEU B 311
1.27A22.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE B 235
ASP B 239
LEU B 248
PHE B 302
LEU B 311
1.27A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
ILE A 249
LEU A 250
PHE A 294
THR A 201
LEU A 205
1.55A20.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
ILE A 249
LEU A 250
PHE A 294
LEU A 242
THR A 201
1.31A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		7 / 12
ILE A 249
ILE A 200
LEU A 250
PHE A 294
LEU A 242
THR A 201
LEU A 205
1.46A20.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
ILE A 249
ILE A 200
PHE A 294
LEU A 242
THR A 201
1.35A20.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.39A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.67A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.64A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
ILE A 136
LEU A 115
VAL A 148
PHE A 140
THR A 175
1.62A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2qc2 3C-LIKE PROTEINASE
(-)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.44A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
LEU A 242
THR A 201
1.40A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
THR A 201
LEU A 205
1.62A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.75A21.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		7 / 12
ILE A 249
ILE A 200
LEU A 250
PHE A 294
LEU A 242
THR A 201
LEU A 205
1.50A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.48A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE B 306
LEU B 299
VAL B 236
LEU B 331
THR B 340
1.48A21.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE B 306
LEU B 299
VAL B 236
LEU B 331
THR B 340
1.46A21.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
LEU C 167
VAL C 172
GLY C 125
PHE C 176
THR C 174
1.57A21.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.42A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2w2g NSP3
(SARSr-CoV)		5 / 12
PRO A 479
ILE A 454
VAL A 457
VAL A 448
LEU A 421
1.38A23.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		2wct NSP3
(SARSr-CoV)		5 / 12
PRO A 479
PHE A 414
VAL A 448
GLY A 419
THR A 450
1.62A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ILE A 128
VAL A  84
LEU A 126
THR A  82
LEU A  59
1.36A20.89
None
None
None
None
NA  A1295 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.65A22.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2xyq NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
LEU B  45
VAL A  84
PHE A 250
THR A  48
THR A  93
1.77A15.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.77A20.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ILE A 128
VAL A  84
LEU A 126
THR A  82
LEU A  59
1.35A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.76A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.64A22.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		2xyv NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
LEU B  45
VAL A  84
PHE A 250
THR A  48
THR A  93
1.79A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3aw0 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.46A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 12
PRO C 113
MET C 175
VAL C 115
ILE C 117
LEU B 124
1.41A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 11
ASP H  86
VAL H  18
MET H  80
LEU H  69
THR H  70
1.52A23.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ASP A 367
LEU A 370
ILE A 446
SER A 409
THR A 449
1.30A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 407
VAL B 573
VAL B 574
MET B 557
LEU B 558
0.97A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
VAL B 485
VAL B 487
LEU B 503
MET B 455
THR B 453
1.60A16.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 359
GLY E 488
ASP A 355
MET A 323
THR A 324
1.50A16.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 444
ASP A 367
LEU A 370
THR A 276
THR A 294
1.08A18.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
PRO A 415
HIS A 417
VAL A 293
ASP A 367
MET A 297
1.44A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.76A21.70
None
959  A 350 (-4.4A)
None
None
959  A 350 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3e9s NSP3
(SARSr-CoV)		5 / 10
MET A 209
LEU A 212
ASP A 165
MET A 170
THR A 169
1.79A21.87
None
None
TTT  A 317 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		3e9s NSP3
(SARSr-CoV)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.46A21.30
None
None
TTT  A 317 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.43A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.78A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.48A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
MET A 235
LEU A 232
LEU B 227
THR B 225
LEU B 262
1.34A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		7 / 12
ILE A 249
ILE C 200
LEU A 250
PHE A 294
LEU A 242
THR C 201
LEU C 205
1.62A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A  67
VAL A  91
VAL A  77
PHE A  66
SER A  65
1.79A21.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE B 249
ILE B 200
LEU B 250
LEU B 242
THR B 201
LEU B 205
1.44A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.45A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		7 / 12
ILE A 249
ILE A 200
LEU A 250
PHE A 294
LEU A 242
THR A 201
LEU A 205
1.53A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
THR A 201
LEU A 205
1.63A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		3i6g BETA-2-MICROGLOBULIN
HLA, A-2
(Homo
sapiens)		5 / 12
LEU E  54
VAL D  12
ASP D 119
SER E  33
LEU D  81
1.38A16.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE C 249
ILE A 200
LEU C 250
LEU C 242
THR A 201
LEU A 205
1.39A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO B  52
LEU B  50
GLY B 174
THR B 190
THR B 175
1.64A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.44A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.67A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.65A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ILE A 249
ILE A 200
LEU A 250
LEU A 242
THR A 201
LEU A 205
1.48A20.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
MET B 209
LEU B 212
ASP B 165
MET B 170
THR B 169
1.79A21.99
GRM  A 801 (-4.2A)
None
GRM  B 801 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ASP A 287
THR A 266
MET A 294
THR A 292
LEU A 291
1.53A19.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ILE A 128
VAL A  84
LEU A 126
THR A  82
LEU A  59
1.35A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.62A21.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 10
LEU B  45
VAL A  84
PHE A 250
THR A  48
THR A  93
1.74A19.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ILE A 127
LEU A 111
VAL A 288
VAL A 290
LEU A 161
PHE A 156
1.73A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		3sci ACE2
(Homo
sapiens)		5 / 12
ILE B 407
VAL B 573
VAL B 574
MET B 557
LEU B 558
1.07A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		3sci ACE2
(Homo
sapiens)		5 / 12
ASP A 367
LEU A 370
ILE A 446
SER A 409
THR A 449
1.49A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3scj ACE2
(Homo
sapiens)		5 / 12
PRO B 415
HIS B 417
VAL B 293
ASP B 367
MET B 297
1.40A17.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 444
ASP A 367
LEU A 370
THR A 276
THR A 294
1.46A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
PRO B 415
HIS B 417
VAL B 293
ASP B 367
MET B 297
1.47A17.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 407
VAL B 573
VAL B 574
MET B 557
LEU B 558
1.10A17.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
ILE B 358
ASP B 382
PHE B 327
THR B 324
THR B  52
1.68A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 359
GLY E 488
ASP A 355
MET A 323
THR A 324
1.55A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
PRO B 590
ILE B 233
ILE B 446
LEU B 520
THR B 519
1.54A17.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		7 / 12
ILE A 249
ILE A 200
LEU A 250
PHE A 294
LEU A 242
THR A 201
LEU A 205
1.51A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
LEU A 242
THR A 201
1.37A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A 168
MET A 165
LEU A 167
PHE A 181
MET A  49
1.73A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
ILE A 200
PHE A 294
LEU A 242
THR A 201
1.44A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 249
LEU A 250
PHE A 294
THR A 201
LEU A 205
1.60A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.53A21.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.46A21.43
None
None
DMS  A 903 (-3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		4wy3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
PRO A  39
LEU A  27
PHE A 140
SER A 144
THR A 135
1.70A21.63
None
None
None
3X5  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5c5o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE B 249
LEU B 250
PHE B 294
THR B 201
LEU B 205
1.61A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
LEU C  75
VAL C  13
GLY D  59
PHE D   8
MET D  62
1.60A19.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PRO D 412
HIS D 427
LEU D 411
ASP D 402
PHE D 401
1.70A19.96
None
None
None
None
G3A  D 606 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ILE B 164
LEU B 170
VAL B 236
SER B 171
THR B 219
1.35A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ILE B  55
LEU B 105
ASP B  10
THR B 103
LEU B  18
1.42A18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr)		5 / 12
ILE B 164
LEU B 170
VAL B 236
SER B 171
THR B 219
1.36A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PRO D 412
HIS D 427
LEU D 411
ASP D 402
PHE D 401
1.73A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ILE B  55
LEU B 105
ASP B  10
THR B 103
LEU B  18
1.50A17.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ILE D 164
LEU D 170
VAL D 236
SER D 171
THR D 219
1.53A17.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5e6j UBIQUITIN
(synthetic
construct)		5 / 12
ILE B  36
ASP B  32
LEU B  71
THR B   9
LEU B   8
1.41A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE D 305
LEU D 102
GLY D 164
MET D 170
THR D 169
1.54A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
LEU N  75
VAL N  13
GLY B  59
PHE B   8
MET B  62
1.56A18.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
ILE A  55
LEU A 105
ASP A  10
THR A 103
LEU A  18
1.44A18.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
PRO A 412
HIS A 427
LEU A 411
ASP A 402
PHE A 401
1.60A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
PRO A 412
HIS A 427
LEU A 411
ASP A 402
PHE A 401
1.60A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE D 305
LEU D 102
GLY D 164
MET D 170
THR D 169
1.56A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ILE B 277
THR B 266
MET B 294
THR B 292
LEU B 291
1.61A19.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5tl6 UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens)		5 / 12
ILE A  84
LEU A 124
VAL A 104
LEU A  82
THR A 101
1.52A13.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
MET D 209
LEU D 212
ASP D 165
MET D 170
THR D 169
1.72A21.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASP C 600
VAL A 842
ASP A 757
LEU A 846
LEU A 847
1.62A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		5 / 10
ILE C  46
LEU C  27
VAL D  29
THR C  30
THR D  35
1.64A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ILE A 256
LEU A  74
LEU A 169
PHE A 112
LEU A 284
1.40A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO A 136
ILE A  81
VAL A 102
ILE A 228
THR A 229
1.52A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE C 852
VAL C 767
LEU C 847
MET C 770
LEU B 681
1.39A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE C 219
VAL C 123
ILE C 116
PHE C 220
SER C 165
1.45A11.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 11
PRO B1035
MET B1032
VAL B 860
PHE B 880
LEU B 876
1.66A11.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
PHE B 782
VAL B1047
GLY B 867
PHE B1034
MET B 884
1.45A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
PRO C 210
HIS C  33
VAL C 206
VAL C 205
THR C  92
1.48A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ILE A 662
LEU A 347
VAL A 363
LEU A 735
LEU A 715
1.64A10.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ILE A 782
ILE A 985
PHE B 967
LEU A 990
THR A 986
1.47A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
LEU C 344
VAL C 360
VAL C 661
ASP A 805
THR A 803
1.79A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_1
(SULFOTRANSFERASE)		5x5c S PROTEIN
(MERS-CoV)		4 / 4
TYR B 642
ASP B 645
ASP B 580
SER B 583
1.34A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
HIS A 670
ILE A 662
VAL A 659
VAL A 363
LEU A 735
1.07A11.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
ILE C 256
LEU C  74
LEU C 169
PHE C 112
LEU C 284
1.38A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO A 697
LEU C 876
GLY A1026
ASP A1023
THR C 869
1.62A12.16
PRO  A 697 ( 1.1A)
LEU  C 876 ( 0.6A)
GLY  A1026 ( 0.0A)
ASP  A1023 ( 0.5A)
THR  C 869 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO A 617
LEU A 615
VAL A 581
ASP A 600
THR C 841
1.69A12.24
PRO  A 617 ( 1.1A)
LEU  A 615 ( 0.6A)
VAL  A 581 ( 0.6A)
ASP  A 600 ( 0.5A)
THR  C 841 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ILE C 787
LEU C 859
VAL C1015
THR C 863
THR C 705
1.52A12.24
ILE  C 787 ( 0.7A)
LEU  C 859 ( 0.6A)
VAL  C1015 ( 0.6A)
THR  C 863 ( 0.8A)
THR  C 705 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
MET A 209
LEU A 212
ASP A 165
MET A 170
THR A 169
1.78A21.49
None
None
GOL  A 408 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.56A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASP B 790
LEU B 804
THR B 795
THR B 921
LEU B 920
1.50A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6acg ACE2
(Homo
sapiens)		5 / 10
ILE D 358
ASP D 382
PHE D 327
THR D 324
THR D  52
1.71A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO B 210
HIS B  33
VAL B 206
VAL B 205
THR B  92
1.34A12.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
ILE B 570
ASP B 518
VAL B 525
ASP B 572
LEU B 532
1.70A12.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 674
LEU B 283
VAL B 583
ILE B 299
LEU B 636
1.46A12.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6ack ACE2
(Homo
sapiens)		5 / 12
LEU D 444
ASP D 367
LEU D 370
THR D 276
THR D 294
1.41A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO C 697
LEU B 876
GLY C1026
ASP C1023
THR B 869
1.30A12.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PRO B 210
HIS B  33
LEU B 209
VAL B 206
VAL B 205
1.71A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ILE A 787
LEU A 859
VAL A1015
THR A 863
THR A 705
1.53A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PRO A 136
ILE A  81
VAL A 102
ILE A 228
THR A 229
1.45A11.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE C 782
VAL C1047
GLY C 867
PHE C1034
MET C 884
1.42A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE A 782
VAL A1047
GLY A 867
PHE A1034
MET A 884
1.35A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PRO A1072
ILE A 696
ILE B 878
PHE A1057
THR B 869
1.22A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ILE B 787
LEU B 859
VAL B1015
THR B 863
THR B 705
1.38A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE B 787
LEU B 859
VAL B1015
THR B 863
THR B 705
1.37A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PRO C 210
HIS C  33
VAL C 206
VAL C 205
THR C  92
1.37A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6cs2 ACE2
(Homo
sapiens)		6 / 12
VAL D 485
VAL D 487
LEU D 503
MET D 455
LEU D 456
THR D 453
1.70A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6cs2 ACE2
SPIKE
GLYCOPROTEIN,FIBRITI
N
(Homo
sapiens;
SARSr-CoV)		5 / 12
LEU D 359
GLY B 488
ASP D 355
MET D 323
THR D 324
1.53A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PRO A 210
HIS A  33
LEU A 209
VAL A 206
VAL A 205
1.64A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
PRO A 364
LEU A 352
VAL A 371
VAL A 305
LEU A 252
1.42A17.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6jyt HELICASE
(SARSr-CoV)		5 / 12
PRO A 364
LEU A 352
VAL A 371
VAL A 305
ASP A 369
1.63A17.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ILE B 109
ASP B 119
LEU B 122
THR B 141
THR A 115
1.35A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
PRO A 364
LEU A 352
VAL A 305
GLY A 251
ASP A 369
1.63A17.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6lzg ACE2
(Homo
sapiens)		5 / 12
ASP A 367
LEU A 370
ILE A 446
SER A 409
THR A 449
1.46A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6m17 ACE2
(Homo
sapiens)		5 / 12
ILE B 407
VAL B 573
VAL B 574
MET B 557
LEU B 558
1.31A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6m17 ACE2
(Homo
sapiens)		5 / 12
ASP B 367
LEU B 370
ILE B 446
SER B 409
THR B 449
1.39A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE A 132
LEU A 427
VAL A  55
ASP A 486
LEU A 482
1.36A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
PRO C  59
LEU C 398
VAL C 320
VAL C 321
PHE C 420
1.68A16.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 11
PRO C 442
VAL C 441
PHE C 289
SER C 288
LEU C 208
1.76A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		6m1d ACE2
(Homo
sapiens)		5 / 11
ILE B 544
ASP B 543
SER B 317
LEU B 410
THR B 414
1.52A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
PRO C 265
ILE C 545
VAL C 552
VAL C 551
LEU C 495
1.19A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 724
ASP A 976
LEU A 734
LEU A 745
THR A 743
1.51A11.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 12
PRO A1035
ILE A 852
VAL A 767
LEU A 847
MET A 770
LEU B 681
1.70A11.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE C 782
VAL C1047
GLY C 867
PHE C1034
MET C 884
1.45A12.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		5 / 12
PHE H  68
VAL H 123
GLY H  44
THR H 121
THR H  43
1.58A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		6 / 12
PRO H 140
LEU H 203
VAL H 196
VAL H 198
SER H 202
THR H 174
1.77A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6nur NSP8
(SARSr-CoV)		5 / 12
ILE D 156
LEU D 128
VAL D 132
VAL D 130
LEU D 169
1.58A22.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 12
PRO A 378
ILE B 119
VAL A 341
VAL A 330
LEU A 271
1.55A15.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 11
PHE A 368
SER A 518
MET B  90
LEU B  91
THR B  89
1.74A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6nus NSP12
(SARSr-CoV)		5 / 12
ILE A 244
ASP A 465
LEU A 127
THR A 123
LEU A 212
1.47A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		6nus NSP12
(SARSr-CoV)		5 / 12
PRO A 296
PHE A 287
LEU A 280
MET A 463
THR A 246
1.55A15.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6vw1 ACE2
(Homo
sapiens)		5 / 12
LEU A 444
ASP A 367
LEU A 370
THR A 276
THR A 294
1.30A17.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6vw1 ACE2
(Homo
sapiens)		5 / 12
ILE B 407
VAL B 573
VAL B 574
MET B 557
LEU B 558
1.16A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
PRO L 113
LEU L 201
VAL L 115
ILE L 117
LEU L 179
1.63A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ILE L  75
LEU L  15
VAL L  83
LEU L  73
LEU L  47
1.53A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ILE L 117
LEU L 175
VAL L 205
VAL L 196
SER L 177
1.58A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
LEU H 141
VAL H 211
ILE H 195
LEU H 159
THR H 193
1.73A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
PRO H 126
LEU H 189
VAL H 182
VAL H 184
THR H 160
1.78A18.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ILE L  75
LEU L  15
VAL L  83
LEU L  73
LEU L  47
1.49A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
PRO L 113
LEU L 201
VAL L 115
ILE L 117
LEU L 179
1.64A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
LEU H 141
VAL H 182
VAL H 181
PHE L 118
THR H 135
1.78A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		6 / 12
PRO H 126
LEU H 189
VAL H 182
VAL H 184
SER H 188
THR H 160
1.77A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
PRO H 126
LEU H 189
VAL H 184
SER H 188
THR H 160
1.71A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
LEU H 141
VAL H 182
VAL H 181
PHE L 118
THR H 135
1.78A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		6 / 12
PRO H 126
LEU H 189
VAL H 182
VAL H 184
SER H 188
THR H 160
1.71A18.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
LEU H 141
VAL H 182
VAL H 181
PHE L 118
THR H 135
1.77A18.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE L 123
LEU L 181
VAL L 211
VAL L 202
SER L 183
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 142
LEU H 142
PHE L 124
LEU H 193
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE L  81
LEU L  15
VAL L  89
LEU L  79
LEU L  53
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU H 163
VAL H 185
VAL H 186
SER H 165
THR L 170
1.75A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE C  81
LEU C  15
VAL C  89
LEU C  79
LEU C  53
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE C 123
LEU C 181
VAL C 211
VAL C 202
SER C 183
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU B 193
VAL B 186
VAL B 188
SER B 192
THR B 164
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU B 193
VAL B 186
VAL B 188
SER B 192
THR B 164
1.64A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		6 / 12
PRO H 130
LEU H 193
VAL H 186
VAL H 188
SER H 192
THR H 164
1.67A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU H 193
VAL H 186
VAL H 188
SER H 192
THR H 164
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
PRO H 130
LEU H 193
VAL H 186
SER H 192
THR H 164
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO C 119
LEU C 207
VAL C 121
ILE C 123
LEU C 185
1.65A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU H 163
VAL H 185
VAL H 186
SER H 165
THR L 170
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 207
VAL L 121
ILE L 123
LEU L 185
1.64A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU B 163
VAL B 185
VAL B 186
SER B 165
THR C 170
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE C  81
LEU C  15
VAL C  89
LEU C  79
LEU C  53
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO C 119
LEU C 142
LEU B 142
PHE C 124
LEU B 193
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
PRO H 130
LEU H 193
VAL H 186
VAL H 188
THR H 164
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU B 163
VAL B 185
VAL B 186
SER B 165
THR C 170
1.77A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 207
VAL L 121
ILE L 123
LEU L 185
1.71A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 142
LEU H 142
PHE L 124
LEU H 193
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE L  81
LEU L  15
VAL L  89
LEU L  79
LEU L  53
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ILE L 123
LEU L 181
VAL L 211
VAL L 202
SER L 183
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L 142
VAL L 121
LEU H 142
PHE L 124
LEU H 193
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		6 / 12
PRO H 130
LEU H 193
VAL H 186
VAL H 188
SER H 192
THR H 164
1.72A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 142
LEU H 142
PHE L 124
LEU H 193
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ILE L  81
LEU L  15
VAL L  89
LEU L  79
LEU L  53
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
PRO C 119
LEU C 142
LEU B 142
PHE C 124
LEU B 193
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ILE L 123
LEU L 181
VAL L 211
VAL L 202
SER L 183
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PRO H 130
LEU H 193
VAL H 186
SER H 192
THR H 164
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU H 163
VAL H 185
VAL H 186
SER H 165
THR L 170
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
PRO B 130
LEU B 193
VAL B 186
VAL B 188
SER B 192
THR B 164
1.67A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
PRO L 119
LEU L 207
VAL L 121
ILE L 123
LEU L 185
1.64A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PRO H 130
LEU H 193
VAL H 186
VAL H 188
THR H 164
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU B 163
VAL B 185
VAL B 186
SER B 165
THR C 170
1.74A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
PRO C 119
LEU C 207
VAL C 121
ILE C 123
LEU C 185
1.63A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
LEU B 193
VAL B 186
VAL B 188
SER B 192
THR B 164
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ILE C 123
LEU C 181
VAL C 211
VAL C 202
SER C 183
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
PRO H 130
LEU H 193
VAL H 186
VAL H 188
SER H 192
THR H 164
1.67A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PRO B 130
LEU B 193
VAL B 186
VAL B 188
THR B 164
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PRO B 130
LEU B 193
VAL B 186
SER B 192
THR B 164
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU B 163
VAL B 185
VAL B 186
SER B 165
THR C 170
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
LEU H 193
VAL H 186
VAL H 188
SER H 192
THR H 164
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ILE C  81
LEU C  15
VAL C  89
LEU C  79
LEU C  53
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU H 163
VAL H 185
VAL H 186
SER H 165
THR L 170
1.75A21.45
None