Ligand ID: FCN


Drugbank ID:
DB00828
(Fosfomycin)


Indication:
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.

Get human targets for FCN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'FCN' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
GLY A 170
GLY B 215
ILE B 213
GLY B   2
SER B   1
1.65A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
GLY A 170
HIS A 172
GLY B  -1
SER B   1
SER B   0
1.20A21.02
None
I12  A1145 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		1x7q HLA, A-11
(Homo
sapiens)		5 / 12
TYR A 171
TYR A  59
GLU A  63
ARG A 163
TYR A 159
1.40A17.92
None
None
None
SO4  A4003 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		1x7q HLA, A-11
(Homo
sapiens)		5 / 12
TYR A 171
TYR A  59
GLU A  63
ARG A 163
TYR A 159
1.41A19.17
None
None
None
SO4  A4003 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 8
LEU D 257
ASN D 219
HIS D 276
HIS D 227
1.31A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		2ajf ACE2
(Homo
sapiens)		4 / 8
TYR B 515
HIS B 374
HIS B 378
ALA B 403
1.32A16.67
None
ZN  B 901 (-3.6A)
ZN  B 901 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		2bx4 3C-LIKE PROTEINASE
(SARS-COV
Sin2774)		5 / 12
HIS A 172
GLU A 166
HIS A 163
TYR A 118
ALA A 116
1.78A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 8
GLY F 317
GLY E 288
ILE E 358
GLY E 285
SER F 319
1.29A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 8
LEU B  76
ASN B  38
HIS B  95
HIS B  46
1.28A19.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
TYR A  73
LEU A 151
ASN A  14
ALA A 136
1.32A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2fyg REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 8
GLY A  69
GLY A  70
ILE A  55
SER A  67
THR A  56
1.54A22.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 8
GLY C  69
GLY C  70
ILE C  55
SER C  67
THR C  56
1.54A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A  71
GLY A  71
GLY A   1
SER A  67
0.77A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A   1
GLY A  71
GLY A  71
HIS A  72
0.78A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A  71
GLY A   1
HIS A   2
THR A  68
0.80A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 8
GLY A  71
GLY A  71
GLY A   1
HIS A   2
SER A  67
1.25A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A  71
GLY A   1
GLY A   1
SER A  67
0.66A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A   1
GLY A   1
GLY A  71
HIS A  72
0.72A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A   1
GLY A   1
SER A  67
SER A  67
0.87A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A  71
GLY A  71
HIS A  70
THR A  68
0.88A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A   1
GLY A   1
GLY A  71
HIS A  70
0.75A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A  71
GLY A  71
GLY A   1
HIS A   2
0.83A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A 116
GLY A 116
GLY A 116
THR A  68
0.52A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 8
GLY A 317
GLY B 288
ILE B 358
GLY B 285
SER A 319
1.31A16.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
GLY A 143
HIS A 172
ILE A 136
GLY A 146
SER A 144
1.59A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 8
GLY A 246
GLY A 247
HIS A 234
ILE A 235
THR A 340
1.31A18.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 8
GLY A  87
GLY A  94
ILE A  60
GLY A  90
SER A  89
1.68A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 8
GLY A 146
GLY A 174
HIS A 163
ILE A 136
GLY A 149
1.67A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 8
GLY D 246
GLY D 247
HIS D 249
ILE D 235
SER D 241
1.55A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 8
GLY D 246
GLY D 247
HIS D 249
ILE D 235
SER D 241
1.51A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 8
GLY B   2
GLY A 138
HIS A 172
ILE A 136
SER B   1
1.75A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 8
GLY B 146
GLY B 174
HIS B 163
ILE B 136
GLY B 149
1.67A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
LEU B 141
HIS B 172
GLU B 166
HIS B 163
1.43A21.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
HIS B 172
GLU B 166
HIS B 163
TYR B 118
ALA B 116
1.75A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 8
HIS A 172
ILE A 136
GLY A 146
SER A 147
SER A 144
1.71A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		2wct NSP3
(SARSr-CoV)		5 / 8
GLY A 466
GLY A 465
GLY D 465
GLY A 494
SER A 461
1.61A24.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2xyr NSP10
(SARSr-CoV)		5 / 8
GLY B  69
GLY B  70
ILE B  55
SER B  67
THR B  56
1.53A16.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		2xyv NSP10
(SARSr-CoV)		5 / 8
GLY B  69
GLY B  70
ILE B  55
SER B  67
THR B  56
1.56A16.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
GLY B 170
GLY A 215
ILE A 213
GLY A   2
SER A   1
1.66A20.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
LEU A 558
ASN A 394
HIS A 401
ALA A 384
1.44A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 8
GLY B 352
GLY B 354
GLY F 488
ILE F 489
THR B 324
1.74A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 8
GLY A 170
GLY B 215
ILE B 213
GLY B   2
SER B   1
1.41A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		3e9s NSP3
(SARSr-CoV)		4 / 8
TYR A 297
LEU A 283
ASN A 263
HIS A 276
1.47A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 11
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.76A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 11
HIS A 151
TRP F   3
ALA A 150
GLU D  58
ARG D  65
1.75A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 10
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.75A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 12
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.79A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 12
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.77A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 11
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.74A22.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 10
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.75A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 11
GLU D  58
ARG D  65
HIS A 151
TRP F   3
ALA A 150
1.76A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
LEU B 141
HIS B 172
GLU B 166
HIS B 163
1.43A21.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
HIS A 172
GLU A 166
HIS A 163
TYR A 118
ALA A 116
1.61A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
TYR A  73
LEU A 151
ASN A  14
ALA A 136
1.34A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		3r24 NSP10 AND NSP11
(SARSr-CoV)		5 / 8
GLY B  69
GLY B  70
ILE B  55
SER B  67
THR B  56
1.57A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 8
GLY B 352
GLY B 354
GLY F 488
ILE F 489
THR B 324
1.74A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
LEU A 558
ASN A 394
HIS A 401
ALA A 384
1.39A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 8
GLY A 352
GLY A 354
GLY E 490
ILE E 489
THR A 324
1.55A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 8
GLY B  76
GLY B  75
GLY A 164
SER A 116
SER A 112
1.47A14.98
None
None
None
NA  A 402 (-2.8A)
NA  A 402 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 8
GLY B  76
HIS A 273
SER A 116
SER A 115
THR A 275
1.64A14.98
None
NHE  A 403 ( 3.6A)
NA  A 402 (-2.8A)
NA  A 402 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 8
TYR B  51
LEU B  18
HIS A  80
ALA B  23
1.28A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5c8t NSP10
(SARSr-CoV)		5 / 8
GLY A  69
GLY A  70
ILE A  55
SER A  67
THR A  56
1.33A17.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 8
TYR B  51
LEU B  18
HIS A  80
ALA B  23
1.25A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5dus ORF1A
(MERS-CoV)		4 / 8
GLY A  44
GLY A  49
HIS A  43
ILE A  51
0.86A20.70
APR  A 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
LEU D 283
ASN D 263
HIS D 276
ALA D 279
1.38A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.77A13.56
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.80A13.56
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.75A14.87
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 8
GLY N  69
GLY N  70
ILE N  55
SER N  67
THR N  56
1.38A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
TYR A  51
LEU A  18
HIS M  80
ALA A  23
1.22A19.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.77A13.56
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.79A14.87
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
HIS A 486
CYH A 452
HIS A 487
TYR A 446
GLU A 490
1.77A13.56
None
ZN  A 603 (-2.6A)
ZN  A 603 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.77A13.56
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
HIS A 487
TYR A 446
GLU A 490
HIS A 486
CYH A 452
1.77A13.56
 ZN  A 603 (-3.3A)
None
None
None
ZN  A 603 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
LEU D 283
ASN D 263
HIS D 276
ALA D 279
1.33A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		5x59 S PROTEIN
(MERS-CoV)		5 / 8
GLY A1115
GLY A1118
ILE A1123
SER A1114
THR A1121
1.62A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		5x5c S PROTEIN
(MERS-CoV)		5 / 8
GLY C1120
GLY C1140
ILE C1123
GLY C1118
SER C1114
1.66A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		6acg ACE2
(Homo
sapiens)		5 / 11
HIS D 378
ALA D 348
ARG D 514
TYR D 515
GLU D 402
1.77A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		6acg ACE2
(Homo
sapiens)		5 / 12
ARG D 514
TYR D 515
GLU D 402
HIS D 378
ALA D 348
1.76A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		6acg ACE2
(Homo
sapiens)		5 / 10
ARG D 514
TYR D 515
GLU D 402
HIS D 378
ALA D 348
1.76A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		6acg ACE2
(Homo
sapiens)		5 / 12
ARG D 514
TYR D 515
GLU D 402
HIS D 378
ALA D 348
1.78A13.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		6acg ACE2
(Homo
sapiens)		5 / 10
ARG D 514
TYR D 515
GLU D 402
HIS D 378
ALA D 348
1.78A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR A 622
LEU A 615
ASN A 627
ALA A 609
1.42A10.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6ack ACE2
(Homo
sapiens)		4 / 8
TYR D 515
HIS D 374
HIS D 378
ALA D 403
1.29A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6cs2 ACE2
(Homo
sapiens)		4 / 8
LEU D 529
ASN D 556
GLU D 549
ALA D 532
1.29A15.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
TYR A 819
LEU A 941
HIS A1040
ALA A 938
1.24A11.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6cs2 ACE2
SPIKE
GLYCOPROTEIN,FIBRITI
N
(Homo
sapiens;
SARSr-CoV)		5 / 8
GLY D 352
GLY D 354
GLY B 488
ILE B 489
THR D 324
1.70A19.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6m17 ACE2
(Homo
sapiens)		4 / 8
TYR B 633
LEU B 628
ASN B 712
ALA B 627
1.46A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 8
GLY C 438
GLY C 285
ILE C 287
SER C 118
SER C 122
1.62A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 8
GLY A 285
GLY A 284
ILE A  92
GLY A  99
SER A 288
1.26A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR A 819
LEU A 941
HIS A1040
ALA A 938
1.44A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6nur NSP12
(SARSr-CoV)		5 / 8
GLY A 503
GLY A 559
GLY A 683
SER A 501
THR A 565
1.74A15.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		6nus NSP12
(SARSr-CoV)		4 / 8
TYR A 732
LEU A 240
ASN A 705
HIS A 133
1.25A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		6nus NSP12
(SARSr-CoV)		5 / 9
ARG A 858
TYR A 884
LEU A 883
ASN A 416
ALA A 423
1.72A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 8
GLY H  94
GLY H  95
GLY H  97
ILE H  98
GLY H  35
1.63A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H 133
GLY H 134
SER H 130
SER H 132
1.54A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  97
GLY H  95
GLY H  94
ILE H  34
1.32A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  94
GLY H  95
GLY H  97
ILE H  98
0.84A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
GLY H  28
ILE H  30
GLY H  24
1.18A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  95
GLY H  94
GLY H  35
ILE H  51
1.51A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  97
GLY H  95
GLY H  94
ILE H  34
1.35A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  94
GLY H  95
ILE H  98
GLY H  35
1.42A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  94
ILE H  98
SER H  96
THR H 100
1.30A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H   8
GLY H 106
SER H  21
SER H   7
1.60A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  94
GLY H  95
GLY H  97
THR H  31
1.34A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H 106
ILE H  89
GLY H   8
SER H   7
1.53A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H 133
GLY H 134
SER H 187
SER H 186
1.66A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
GLY H  24
ILE H  34
GLY H  28
1.62A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H   8
GLY H 106
SER H  21
SER H   7
1.53A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
ILE H  75
GLY H  24
SER H  25
1.49A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H 104
SER H   7
SER H  21
THR H 107
1.56A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H 133
GLY H 134
SER H 130
SER H 132
1.52A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
GLY H  95
ILE H  50
GLY H  97
SER H  99
1.54A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
ILE B 102
SER B 100
THR B 104
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
ILE H 102
GLY H  35
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B   8
GLY B 112
ILE B  93
GLY H   8
1.24A
MLI  H 305 (-3.2A)
MLI  B 304 ( 4.8A)
None
MLI  B 304 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
GLY H  28
ILE H  30
GLY H  24
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
GLY B 101
ILE B 102
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B  26
GLY B  28
ILE B  30
GLY B  24
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
ILE B 102
GLY B  35
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
GLY B 101
ILE B 102
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
ILE H 102
SER H 100
THR H 104
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
ILE H 102
GLY H  35
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
ILE H 102
SER H 100
THR H 104
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
GLY H  28
ILE H  30
GLY H  24
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
ILE B 102
SER B 100
THR B 104
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
ILE H 102
GLY H  35
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
ILE B 102
GLY B  35
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY H  26
GLY H  28
ILE H  30
GLY H  24
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
ILE H 102
SER H 100
THR H 104
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY B  26
GLY B  28
ILE B  30
GLY B  24
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QUO_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
GLY B 101
ILE B 102
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY B  98
GLY B  99
GLY B 101
ILE B 102
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
GLY H  98
GLY H  99
GLY H 101
ILE H 102
1.04A
None