Ligand ID: DM5


Drugbank ID:
DB01177
(Idarubicin)


Indication:
For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Get human targets for DM5 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'DM5' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.50A18.90
MPD  A 307 (-4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 6
LYS A  49
ASP A  56
TYR A  54
ARG A  60
1.66A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
VAL B 297
ALA B 210
PHE B   3
LYS B   1
PHE B 291
1.69A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		1z1i 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
MET A 165
ALA A 173
PHE A 181
TYR A  54
1.17A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.50A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		2ajf ACE2
(Homo
sapiens)		4 / 7
LEU B 262
VAL B 488
PRO B 612
TYR B 252
1.50A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		2ajf SPIKE PROTEIN
(SARSr-CoV)		4 / 6
ASP E 429
TRP E 423
TYR E 494
ARG E 495
1.68A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
MET A 165
ALA A 173
PHE A 181
TYR A  54
1.27A18.57
ENB  A 307 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
VAL B 297
ALA B 210
PHE B   3
LYS B   1
PHE B 291
1.71A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
VAL C  58
TYR C  72
GLU C  68
TYR C  73
1.46A18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.50A18.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 7
VAL A 247
PHE A 230
LYS A 269
TYR A 239
1.45A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 7
VAL A 296
PRO A 293
LYS A 137
GLU A 290
1.32A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.46A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 7
PRO B 108
MET B 130
ALA B 129
PHE B 112
1.48A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
VAL B 297
ALA B 210
PHE B   3
LYS B   1
PHE B 291
1.61A18.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 7
VAL B 297
ALA B 210
PHE B   3
LYS B   1
1.45A18.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL A 296
PRO A 293
LYS A 137
GLU A 290
1.25A18.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.44A18.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 7
PRO B 108
MET B 130
ALA B 129
PHE B 112
1.48A18.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
VAL A 297
ALA A 210
PHE A   3
LYS A   1
PHE A 291
1.74A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
MET A 165
ALA A 173
PHE A 181
TYR A  54
1.27A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		4 / 7
VAL S 458
PRO S 477
TYR A 481
TYR A 440
1.33A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP E 429
TRP E 423
TYR E 494
ARG E 495
1.63A15.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP F 429
TRP F 423
TYR F 494
ARG F 495
1.66A14.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3d0i SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP E 429
TRP E 423
TYR E 494
ARG E 495
1.65A14.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		3e9s NSP3
(SARSr-CoV)		4 / 7
VAL A  58
TYR A  72
GLU A  68
TYR A  73
1.52A18.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO B 108
MET B 130
ALA B 129
PHE B 112
1.46A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL A 247
PHE A 230
LYS A 269
TYR A 239
1.47A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL A 296
PRO A 293
LYS A 137
GLU A 290
1.12A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.43A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.51A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		5 / 9
VAL D  25
ALA D  24
PHE F   2
TYR D 159
PHE D  99
1.68A19.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO B 108
MET B 130
ALA B 129
PHE B 112
1.47A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
VAL B 297
ALA B 210
PHE B   3
LYS B   1
PHE B 291
1.69A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL A 296
PRO A 293
LYS A 137
GLU A 290
1.26A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO A 108
MET A 130
ALA A 129
PHE A 112
1.49A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
PRO B 108
MET B 130
ALA B 129
PHE B 112
1.48A19.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3sci SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP E 429
TRP E 423
TYR E 494
ARG E 495
1.71A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3scj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP F 429
TRP F 423
TYR F 494
ARG F 495
1.68A15.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
VAL A 573
MET A 557
ALA A 569
TYR A 385
1.49A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP F 429
TRP F 423
TYR F 494
ARG F 495
1.74A15.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		4 / 7
VAL A  58
TYR A  72
GLU A  68
TYR A  73
1.37A18.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 7
LEU A  80
PRO A  77
LYS A  69
TYR A 155
1.50A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B601_1
(SERUM ALBUMIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 9
LEU A  80
ARG A  82
PRO A  77
LYS A  69
TYR A 155
1.73A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
VAL D  58
PRO D  60
TYR D  72
GLU D  68
1.50A18.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LYS A 188
ASP A  44
TYR A  41
ARG A  48
1.38A19.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A 254
LYS A 198
TYR A 197
TYR A  41
1.39A17.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 7
LEU C1016
VAL C1015
PRO C1035
TYR C 771
1.48A17.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
LYS B 188
ASP B  44
TYR B  41
ARG B  48
1.53A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU A1016
VAL A1015
PRO A1035
TYR A 771
1.51A17.22
LEU  A1016 ( 0.6A)
VAL  A1015 ( 0.6A)
PRO  A1035 ( 1.1A)
TYR  A 771 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP B 429
TRP B 423
TYR B 494
ARG B 495
1.63A19.58
ASP  B 429 ( 0.6A)
TRP  B 423 ( 0.5A)
TYR  B 494 ( 1.3A)
ARG  B 495 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP C 429
TRP C 423
TYR C 494
ARG C 495
1.64A19.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		6acg ACE2
(Homo
sapiens)		4 / 7
VAL D 573
MET D 557
ALA D 569
TYR D 385
1.42A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6acj ACE2
(Homo
sapiens)		4 / 7
LEU D 262
VAL D 488
PRO D 612
TYR D 252
1.45A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU B 499
VAL B 420
LYS B 343
TYR B 383
1.27A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
LEU B1016
VAL B1015
PRO B1035
TYR B 771
1.43A16.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
LEU B1016
VAL B1015
PRO B1035
TYR B 771
1.41A17.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASP A 429
TRP A 423
TYR A 494
ARG A 495
1.52A19.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		6cs2 ACE2
(Homo
sapiens)		4 / 7
ALA D  36
PHE D 390
LYS D 353
TYR D 385
1.47A20.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		6jyt HELICASE
(SARSr-CoV)		4 / 7
VAL B 558
ALA B 403
LYS B 430
TYR B 421
1.49A21.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 9
PRO A 493
ALA A 282
PHE A 283
TYR A 129
PHE A 277
1.71A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6m1d ACE2
(Homo
sapiens)		4 / 7
LEU D 262
VAL D 488
PRO D 612
TYR D 252
1.45A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU C1016
VAL C1015
PRO C1035
TYR C 771
1.39A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU B 182
VAL B 146
PRO B 123
GLU B 152
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU H 182
VAL H 146
PRO H 123
GLU H 152
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU H 182
VAL H 146
PRO H 123
GLU H 152
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
VAL H 117
ALA H 118
PHE H 150
TYR H 149
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
VAL B  11
ALA B 118
PHE B 150
TYR B 149
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU H 182
VAL H 146
PRO H 123
GLU H 152
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU B 182
VAL B 146
PRO B 123
GLU B 152
1.71A
None