Ligand ID: CFF


Drugbank ID:
DB00201
(Caffeine)


Indication:
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.

Get human targets for CFF in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'CFF' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
PHE A  40
LEU A  94
ASN A  95
ILE A  91
1.41A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
GLU A 290
ASP A 295
PHE A   8
ARG A 298
1.76A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.43A22.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.13A16.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.13A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.11A16.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.13A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.14A16.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.12A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PHE B 140
ALA B 116
GLY B 124
TYR B 126
1.17A16.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		1x7q BETA-2-MICROGLOBULIN
HLA, A-11
(Homo
sapiens)		5 / 6
ASN B  24
PHE B  22
HIS B  13
ALA A 236
GLY A 237
1.78A6.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU L  33
LEU L  30
ILE G   5
PHE G   9
1.53A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 6
ASN A 236
HIS A 276
ALA A 232
GLY A 228
1.12A13.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 7
GLU A 208
ILE A 205
ILE A 335
TYR A 191
1.42A3.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		4 / 7
VAL G 135
PHE G 152
ASN G 110
ILE G 125
1.35A18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 9
ILE G 112
VAL C  71
PHE G  97
LEU C  18
MET C  57
1.64A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		2ajf ACE2
(Homo
sapiens)		3 / 3
TRP A 461
THR A 517
TYR A 516
1.76A21.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.45A16.59
ENB  B1145 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.39A16.51
ENB  B1145 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.42A16.51
ENB  B1145 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.43A16.59
ENB  B1145 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  51
TRP H  36
ILE H  34
TYR H  79
1.75A4.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		3 / 3
TRP H  47
THR H  33
TYR S 491
1.74A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 7
ILE H  34
TRP H  47
ILE H  69
TYR S 491
1.43A4.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
ILE H  34
TRP H  47
ILE H  69
TYR S 491
1.40A4.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 7
GLU C  27
ILE C  24
ILE C 154
TYR C  10
1.41A3.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 6
ASN B  55
HIS B  95
ALA B  51
GLY B  47
1.06A13.55
None
None
APR  B 477 ( 3.7A)
APR  B 477 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2ghw SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A 349
PHE C 379
ASN C 321
ILE A 319
1.45A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		3 / 3
TRP D  47
THR C 486
TYR C 484
1.43A19.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 7
VAL A 275
PHE A 329
LEU A 297
ILE A 322
1.35A22.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 7
ILE A 293
PHE A 364
TRP A 302
TYR A 299
1.64A2.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 7
VAL A  52
PHE A  32
LEU A 105
ASN A 101
MET A  39
1.39A15.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 9
VAL A  52
PHE A  32
LEU A 105
ASN A 101
MET A  39
1.63A14.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		4 / 7
VAL A  52
PHE A  32
LEU A 105
MET A  39
0.68A15.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 7
VAL C 320
PHE C 302
LEU C 248
ILE C 295
1.16A22.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU C 299
LEU C 227
ILE C 235
PHE C 232
1.29A23.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.45A22.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 6
HIS A 172
ALA A 116
GLY A 124
TYR A 126
1.46A15.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.53A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.50A22.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 7
VAL E 275
PHE E 329
LEU E 297
ILE E 322
1.24A23.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
HIS A 172
ALA A 116
GLY A 124
TYR A 126
1.29A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 6
PHE B 140
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.41A16.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
HIS A 172
ALA A 116
GLY A 124
TYR A 126
1.34A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 6
PHE B 140
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.39A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 6
PHE B 140
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.40A16.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
ASP B 216
LEU B 208
PHE B 219
ILE B 286
1.53A22.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
HIS A 172
ALA A 116
GLY A 124
TYR A 126
1.32A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
HIS A 172
ALA A 116
GLY A 124
TYR A 126
1.36A16.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASP A 130
LEU A  50
PHE A 205
ILE A 167
1.41A20.17
SAH  A1293 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASP A 130
LEU A  50
PHE A 205
ILE A 167
1.44A19.89
SFG  A1298 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.51A22.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		3bgf F26G19 FAB
(Mus
musculus)		4 / 6
GLU L  38
ILE L  44
ILE H  37
TYR L  87
1.71A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		3bgf F26G19 FAB
(Mus
musculus)		4 / 7
GLU C  38
ILE C  44
ILE B  37
TYR C  87
1.64A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
GLU B 227
ILE B 223
ILE B 513
TYR B 454
1.54A7.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASN B 142
HIS B 163
ALA B 116
GLY B 124
1.29A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.26A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.28A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.29A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.32A17.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.24A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.29A17.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.44A22.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TA3_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		3i6k HLA, A-2
(Homo
sapiens)		4 / 6
TYR A   7
ILE A  52
TRP A  60
TYR A  59
1.57A4.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		4 / 7
VAL D 152
LEU F   9
ASN D  77
ILE D 124
1.49A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.53A22.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.53A22.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASN A 177
HIS A 225
ALA A 178
TYR A 181
1.18A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASP A 130
LEU A  50
PHE A 205
ILE A 167
1.39A21.51
SAM  A 302 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASN A 177
HIS A 225
ALA A 178
TYR A 181
1.17A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
ASN A 177
HIS A 225
ALA A 178
TYR A 181
1.18A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
ASP A  30
LEU E 443
PHE E 442
ILE E 405
1.29A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
GLU A 227
ILE A 223
ILE A 513
TYR A 454
1.57A8.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
TRP A 461
THR A 517
TYR A 516
1.67A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ASP A 292
LEU A 418
ILE A 307
PHE A 369
1.47A20.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ASP A 216
LEU A 208
PHE A 219
ILE A 286
1.52A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 7
VAL A  90
MET A  95
LEU A 113
ILE A 152
1.40A19.67
None
PO4  A 402 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 6
LEU A  56
ASP A  58
ILE A  40
PHE A  34
1.43A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
HIS B 172
ALA B 116
GLY B 124
TYR B 126
1.42A16.16
3A7  B 401 ( 4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
VAL B 405
PHE B 506
LEU B 409
ASN B 422
1.45A19.78
None
G3A  B 606 (-3.8A)
None
G3A  B 606 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.41A20.02
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.40A20.02
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.40A20.02
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
ILE D 510
PHE D 445
ILE D 397
TRP D 385
1.46A7.12
None
None
None
G3A  D 606 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.44A20.48
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.41A20.02
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.39A20.02
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.46A20.45
None
ZN  B 603 (-2.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 9
ILE B  87
VAL B 115
GLU B 191
LEU B 109
ILE B 166
1.71A21.47
None
None
MG  B 604 (-2.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.43A19.98
None
ZN  B 603 (-2.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
ILE D 510
PHE D 445
ILE D 397
TRP D 385
1.53A7.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.45A19.98
None
ZN  B 603 (-2.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
VAL B 199
PHE B 183
MET B 169
ILE B 166
1.47A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.45A20.12
None
ZN  B 603 (-2.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.37A19.98
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.35A20.12
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.37A19.98
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
LEU D 321
LEU D 519
ILE D 510
PHE D 514
1.53A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.36A20.12
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.40A20.02
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.38A20.05
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
GLU B 490
TYR B 446
ASP B 449
PHE B 523
1.68A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
ASN B 478
HIS B 487
ALA B 482
GLY B 480
1.35A19.98
None
ZN  B 603 (-2.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		5f22 NSP8
NSP7
(SARSr-CoV)		5 / 9
ILE B 112
VAL A  71
PHE B  97
LEU A  18
MET A  57
1.65A14.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5f22 NSP8
(SARSr-CoV)		4 / 7
VAL B 135
PHE B 152
ASN B 110
ILE B 125
1.47A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
VAL A 199
PHE A 183
MET A 169
ILE A 166
1.47A19.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
GLU D  78
ILE D  74
TRP D  86
ILE D 242
1.74A7.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5tl6 REPLICASE
POLYPROTEIN 1AB
UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens;
SARSr-CoV)		4 / 7
VAL D 226
PHE C 126
LEU C  82
ILE C  84
1.36A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU A 209
PHE A 253
ILE A  87
PHE A  89
1.40A21.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
LEU C 209
PHE C 253
ILE C  87
PHE C  89
1.52A15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		5x59 S PROTEIN
(MERS-CoV)		4 / 7
ILE A 573
PHE A 385
ILE A 433
TYR A 438
1.76A12.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		5x59 S PROTEIN
(MERS-CoV)		4 / 6
LEU A 840
ASP A 843
LEU A 935
ILE C 662
1.45A14.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN C 910
PHE C 909
ALA C 906
GLY C 780
1.38A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.36A22.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN C 910
PHE C 909
ALA C 906
GLY C 780
1.39A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.35A22.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.36A22.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.37A22.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.32A22.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5x5c S PROTEIN
(MERS-CoV)		4 / 7
VAL C1124
PHE C 972
LEU C1005
ASN C1002
1.30A13.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN B1002
PHE B1001
ALA B 998
GLY B 867
1.45A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN B1002
PHE B1001
ALA B 998
GLY B 867
1.47A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN B1002
PHE B1001
ALA B 998
GLY B 867
1.47A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN B1002
PHE B1001
ALA B 998
GLY B 867
1.44A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		5x5f S PROTEIN
(MERS-CoV)		5 / 9
ILE C1054
VAL C1060
GLU C 818
LEU C 820
ILE C1067
1.68A15.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN B1002
PHE B1001
ALA B 998
GLY B 867
1.46A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.45A22.20
ASN  A 910 ( 0.6A)
PHE  A 909 ( 1.3A)
ALA  A 906 ( 0.0A)
GLY  A 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.44A22.20
ASN  A 910 ( 0.6A)
PHE  A 909 ( 1.3A)
ALA  A 906 ( 0.0A)
GLY  A 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 781
1.38A22.29
ASN  B 910 ( 0.6A)
PHE  B 909 ( 1.3A)
ALA  B 906 ( 0.0A)
GLY  B 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A 969
LEU A 734
ASN A 733
ILE A 975
1.50A13.70
VAL  A 969 ( 0.6A)
LEU  A 734 ( 0.6A)
ASN  A 733 ( 0.6A)
ILE  A 975 ( 0.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.41A22.20
ASN  A 910 ( 0.6A)
PHE  A 909 ( 1.3A)
ALA  A 906 ( 0.0A)
GLY  A 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.44A22.29
ASN  A 910 ( 0.6A)
PHE  A 909 ( 1.3A)
ALA  A 906 ( 0.0A)
GLY  A 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.46A20.45
ASN  A 910 ( 0.6A)
PHE  A 909 ( 1.3A)
ALA  A 906 ( 0.0A)
GLY  A 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 781
1.44A20.45
ASN  B 910 ( 0.6A)
PHE  B 909 ( 1.3A)
ALA  B 906 ( 0.0A)
GLY  B 781 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		4 / 7
GLU a  33
ILE a  29
ILE A 916
TYR a  36
1.65A1.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE C 117
VAL C 102
ASN C 135
MET C 151
ILE C 152
1.71A15.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.13A22.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.14A22.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.14A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.15A22.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP A 961
LEU B 532
ILE A  46
PHE B 551
1.28A14.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.08A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.13A20.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 910
PHE B 909
ALA B 906
GLY B 780
1.16A20.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ILE A  81
TRP A 101
ILE A  87
TYR A 252
1.61A12.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL C 969
LEU C 734
ASN C 733
ILE C 975
1.36A13.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6ack ACE2
(Homo
sapiens)		4 / 7
GLU D 227
ILE D 223
ILE D 513
TYR D 454
1.40A8.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6ack ACE2
(Homo
sapiens)		3 / 3
TRP D 461
THR D 453
TYR D 516
1.73A21.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.17A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
LEU C 209
PHE C 253
ILE C  87
PHE C  89
1.43A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
ILE C1097
PHE C1085
TRP C1084
ILE C1063
1.55A12.60
None
NAG  C1308 (-4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.16A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.22A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ILE B1097
PHE B1085
TRP B1084
ILE B1063
1.44A12.60
None
NAG  B1308 (-4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.18A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.18A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.17A21.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY A 739
TYR A 738
1.20A21.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
VAL A 196
PHE A 103
LEU A 224
ILE A 125
1.27A13.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ILE B  81
TRP B 101
ILE B  87
TYR B 252
1.56A12.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.11A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.17A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.17A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.19A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.17A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.15A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.16A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
GLU B 593
ILE B 584
ILE B 650
TYR B 660
1.70A12.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
ILE C1097
PHE C1085
TRP C1084
ILE C1063
1.56A12.56
None
NAG  C1327 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ILE C1097
PHE C1085
TRP C1084
ILE C1063
1.45A12.56
None
NAG  C1327 (-4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6cs2 ACE2
(Homo
sapiens)		4 / 7
VAL D 184
LEU D 120
ASN D 508
ILE D 119
1.40A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6cs2 ACE2
(Homo
sapiens)		4 / 7
GLU D 227
ILE D 223
ILE D 513
TYR D 454
1.55A7.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		4 / 6
TRP A 167
GLU A 163
TYR A 159
PHE A  33
1.72A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6iex BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 6
ASN B  24
PHE B  22
HIS B  13
ALA A 236
GLY A 237
1.79A7.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6iex BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 6
ASN B  24
PHE B  22
HIS B  13
ALA A 236
GLY A 237
1.77A7.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6iex BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 6
ASN B  24
PHE B  22
HIS B  13
ALA A 236
GLY A 237
1.77A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6jyt HELICASE
(SARSr-CoV)		4 / 6
GLU B 447
ILE B 448
ILE B 572
TRP B 506
1.72A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6jyt HELICASE
(SARSr-CoV)		4 / 7
VAL A 360
LEU A 384
ASN A 381
ILE A 376
1.43A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6jyt HELICASE
(SARSr-CoV)		4 / 6
GLU B 447
ILE B 448
ILE B 572
TRP B 506
1.60A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6jyt HELICASE
(SARSr-CoV)		4 / 6
GLU B 447
ILE B 448
ILE B 572
TRP B 506
1.72A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m17 ACE2
(Homo
sapiens)		4 / 6
GLU D 699
ILE D 695
ILE D 663
TYR D 654
1.36A10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 7
VAL A 320
PHE A 403
LEU A 244
MET A 410
1.30A17.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m17 ACE2
(Homo
sapiens)		4 / 6
GLU D 699
ILE D 695
ILE D 663
TYR D 654
1.39A10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
ASN C 515
PHE C 514
GLY C 510
TYR C 509
1.48A22.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m17 ACE2
(Homo
sapiens)		4 / 7
GLU D 699
ILE D 695
ILE D 663
TYR D 654
1.28A10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6m17 ACE2
(Homo
sapiens)		4 / 7
PHE D 724
LEU D 717
ASN D 712
ILE D 622
1.52A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
ASN C 515
PHE C 514
GLY C 510
TYR C 509
1.44A22.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
ILE A 133
TRP A  56
ILE A 136
TRP A 176
1.45A8.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
GLU C 300
ILE C 522
ILE C 518
TRP C 534
1.58A8.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6m1d ACE2
(Homo
sapiens)		5 / 9
ILE D 727
VAL D 647
PHE D 724
GLU D 723
ILE D 618
1.69A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 11
TYR C 292
GLY C 215
GLU C 437
TYR C  41
TRP C  35
1.59A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 11
TYR C 292
GLY C 215
GLU C 437
TYR C  41
TRP C  35
1.71A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
GLU A 300
ILE A 522
ILE A 518
TRP A 534
1.59A8.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6m1d ACE2
(Homo
sapiens)		4 / 6
ASP B 382
PHE B 356
ILE B 358
PHE B 327
1.37A18.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
LEU A 140
LEU A 424
ILE A 407
PHE A 420
1.34A21.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 7
GLU A 300
ILE A 522
ILE A 518
TRP A 534
1.56A8.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6m1d ACE2
(Homo
sapiens)		3 / 3
TRP D 594
THR D 282
TYR D 279
1.61A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.35A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.33A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ILE C1097
PHE C1085
TRP C1084
ILE C1063
1.46A12.92
None
NAG  C1344 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 780
1.34A20.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAT_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
GLU A 593
ILE A 584
ILE A 650
TYR A 660
1.75A12.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN C 951
PHE C 952
GLY B 739
TYR B 738
1.19A20.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.34A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAN_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
GLU A 593
ILE A 584
ILE A 650
TYR A 660
1.63A12.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.30A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE A 787
VAL A1047
PHE A 784
MET A 884
ILE A 913
1.78A15.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 910
PHE A 909
ALA A 906
GLY A 781
1.32A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
ILE C1097
PHE C1085
TRP C1084
ILE C1063
1.56A12.92
None
NAG  C1344 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6nur NSP12
NSP8
(SARSr-CoV)		4 / 7
VAL B  83
LEU A 372
MET A 566
ILE A 562
1.19A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6nus NSP8
(SARSr-CoV)		4 / 7
ILE B 156
PHE B 147
ILE B 172
TRP B 182
1.57A3.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6nus NSP12
NSP8
(SARSr-CoV)		4 / 6
LEU B  95
ASP B  99
LEU B 103
ILE A 333
1.42A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6vw1 ACE2
(Homo
sapiens)		4 / 6
ASP A 292
LEU A 418
ILE A 307
PHE A 369
1.42A20.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6vw1 ACE2
(Homo
sapiens)		4 / 7
GLU B 227
ILE B 223
ILE B 513
TYR B 454
1.47A7.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  69
TYR H  79
1.63A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  51
TYR H  79
1.40A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  69
TYR H  79
1.65A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  69
TYR H  79
1.63A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  69
TYR H  79
1.63A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  51
TYR H  79
1.40A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  51
TYR H  79
1.41A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
TRP H  33
THR L  94
TYR L  96
1.76A18.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  51
TYR H  79
1.42A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.12A2.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
VAL B  37
PHE B  64
LEU B  81
ILE B  70
1.61A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.11A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.69A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
TRP B  33
THR C 100
TYR C 102
1.73A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.69A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.68A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
TRP H  33
THR L 100
TYR L 102
1.72A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.69A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.69A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.70A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
VAL H  37
PHE H  64
LEU H  81
ILE H  70
1.58A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.68A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.14A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.12A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.14A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ASP B 107
LEU B   4
ILE B  30
PHE B  29
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.68A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ASP H 107
LEU H   4
ILE H  30
PHE H  29
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.71A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.35A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.34A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.71A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.71A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.72A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.16A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.16A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
VAL H  37
PHE H  64
LEU H  81
ILE H  70
1.60A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.34A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.15A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.17A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.35A3.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.70A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.11A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.12A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.31A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
VAL H  37
PHE H  64
LEU H  81
ILE H  70
1.59A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.71A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.31A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.67A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.68A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ASP B 107
LEU B   4
ILE B  30
PHE B  29
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.11A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.31A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.12A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
TRP H  33
THR L 100
TYR L 102
1.72A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_G_CFFG5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.31A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.12A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ASP H 107
LEU H   4
ILE H  30
PHE H  29
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
VAL B  37
PHE B  64
LEU B  81
ILE B  70
1.58A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAP_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.32A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.70A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_B_CFFB5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.70A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
TRP B  33
THR C 100
TYR C 102
1.72A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
ILE H  70
TYR H  80
1.69A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE H  34
PHE H  29
TRP H  33
ILE H  50
1.11A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_E_CFFE5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
TRP B  33
ILE B  50
1.13A3.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TAV_I_CFFI5102_1
(RYANODINE RECEPTOR 1)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
ILE B  34
PHE B  29
ILE B  70
TYR B  80
1.69A3.86
None