 |
| Ligand ID: 9TP Drugbank ID: DB00444(Teniposide) Indication:Teniposide is used for the treatment of refractory acute lymphoblastic leukaemia |
| DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 1ssk | NUCLEOCAPSID PROTEIN (SARSr-CoV) | 5 / 12 | PRO A 146ALA A 151ILE A 108TYR A 65GLY A 102 | 1.59A | 11.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 1ssk | NUCLEOCAPSID PROTEIN (SARSr-CoV) | 5 / 12 | PRO A 146ALA A 151ILE A 108TYR A 65GLY A 102 | 1.54A | 11.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 1wnc | E2 GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | LEU A1167ALA B1171LEU B 927GLY C 928LYS C 929 | 1.43A | 11.78 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 1wof | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | LEU B 141ALA A 7ILE A 213LEU A 282GLY A 215 | 1.52A | 18.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 1z1j | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | LEU A 141ALA B1007ILE B1213LEU B1282GLY B1215 | 1.59A | 18.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 2ajf | ACE2 (Homosapiens) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.50A | 20.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 2fe8 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 5 / 12 | ALA B 146TYR B 36LEU B 81LEU B 59GLY B 33 | 1.51A | 18.64 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 2q6g | REPLICASEPOLYPROTEIN 1AB (SARS-COVBJ01) | 5 / 12 | LEU B 141ALA A 7ILE A 213LEU A 282GLY A 215 | 1.51A | 18.70 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 2z9j | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | LYS A 90TYR A 37LEU A 177GLY A 179LYS A 180 | 1.59A | 18.70 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3bgf | SPIKE PROTEIN S1 (SARSr-CoV) | 5 / 12 | LEU A 443PRO A 459ALA A 471TYR S 442LEU S 478 | 1.41A | 16.17 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 3d0g | ACE2 (Pagumalarvata;Homosapiens;SARSr-CoV) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.51A | 20.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3d0g | ACE2 (Pagumalarvata;Homosapiens;SARSr-CoV) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.45A | 20.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3e9s | NSP3 (SARSr-CoV) | 5 / 12 | ALA A 150TYR A 36LEU A 81LEU A 59GLY A 33 | 1.53A | 18.98 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3ee7 | REPLICASEPOLYPROTEIN 1A (SARSr-CoV) | 5 / 12 | LEU A 4PRO A 6ALA B 107LEU A 97GLY A 93 | 1.54A | 11.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 3ee7 | REPLICASEPOLYPROTEIN 1A (SARSr-CoV) | 5 / 12 | LEU A 4PRO A 6ALA B 107LEU A 97GLY A 93 | 1.53A | 11.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3sci | ACE2 (Homosapiens) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.31A | 20.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 3sci | ACE2 (Homosapiens) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.39A | 20.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 3scl | ACE2 (Pagumalarvata;Homosapiens;SARSr-CoV) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.33A | 20.18 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 3scl | ACE2 (Pagumalarvata;Homosapiens;SARSr-CoV) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.42A | 20.18 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 3to2 | BETA-2-MICROGLOBULINMHC CLASS I ANTIGEN (Homosapiens) | 5 / 12 | LEU A 206ALA A 246TYR B 10HIS B 13GLY A 237 | 1.59A | 18.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 5e6j | POLYUBIQUITIN-BREPLICASEPOLYPROTEIN 1AB (SARSr-CoV;syntheticconstruct) | 5 / 12 | LEU F 8ALA D 69TYR D 155LEU D 133LEU D 173 | 1.35A | 7.86 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 5wrg | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | LEU A 843ALA A 997TYR A 989LEU A 941LEU A 944 | 1.59A | 17.22 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 5x4s | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | ALA A 284ILE A 272LEU A 52ARG A 48GLY A 270 | 1.28A | 17.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 5x58 | SPIKE GLYCOPROTEIN (SARS-COVBJ01) | 5 / 12 | ALA B 284ILE B 272LEU B 52ARG B 48GLY B 270 | 1.32A | 17.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 5x5b | SPIKE GLYCOPROTEIN (SARS-COVBJ01) | 5 / 12 | LEU C 843ALA C 997TYR C 989LEU C 941GLY C 839 | 1.41A | 17.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 5x5c | S PROTEIN (MERS-CoV) | 5 / 12 | LEU A 938ALA A1130TYR A 947LEU A 849ARG A 847 | 1.57A | 17.89 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 5xlr | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | LEU B 843ALA B 997TYR B 989LEU B 941GLY B 839 | 1.44A | 17.22 | LEU B 843 ( 0.6A)ALA B 997 ( 0.0A)TYR B 989 ( 1.3A)LEU B 941 ( 0.6A)GLY B 839 ( 0.0A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 5zvm | PAN-COV INHIBITORYPEPTIDE EK1SPIKE GLYCOPROTEIN (SARSr-CoV;syntheticconstruct) | 5 / 12 | LEU a 25ALA c 28LEU C 927GLY B 928LYS B 929 | 1.25A | 5.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6acj | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | ALA A 284ILE A 272LEU A 52ARG A 48GLY A 270 | 1.24A | 17.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6acj | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | ALA C 683ILE C 656LEU B 847LEU B 846GLY C 653 | 1.37A | 17.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6crv | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | ALA B 284ILE B 272LEU B 52ARG B 48GLY B 270 | 1.14A | 16.95 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6crv | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | ALA B1038HIS B1030LEU B 859LEU B1016GLY B1017 | 1.55A | 16.95 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6crx | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | LEU B 843ALA B 997TYR B 989LEU B 941GLY B 839 | 1.46A | 17.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6cs0 | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | ALA B 284ILE B 272LEU B 52ARG B 48GLY B 270 | 1.15A | 17.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6iex | MHC CLASS I ANTIGEN (Homosapiens;SARSr-CoV) | 5 / 12 | LEU A 81TYR A 116ILE A 124LEU C 8LYS A 146 | 1.48A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_2 (SERUM ALBUMIN) | 6jyt | HELICASE (SARSr-CoV) | 4 / 4 | VAL B 209GLU B 201ASP B 483LYS B 524 | 1.75A | 21.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6jyt | HELICASE (SARSr-CoV) | 5 / 12 | ALA A 469ILE A 575LEU A 500ARG A 595GLY A 494 | 1.52A | 21.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6jyt | HELICASE (SARSr-CoV) | 5 / 12 | PRO B 77ALA B 52TYR B 48GLY B 91LYS B 94 | 1.53A | 21.96 | None ZN B 702 ( 4.2A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6m18 | ACE2 (Homosapiens) | 5 / 12 | LEU B 722ALA D 714ILE B 679TYR B 633LEU B 628 | 1.41A | 21.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6m18 | ACE2 (Homosapiens) | 5 / 12 | LEU B 722ALA D 714ILE B 679TYR B 633LEU B 628 | 1.44A | 21.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6m1d | SODIUM-DEPENDENTNEUTRAL AMINO ACIDTRANSPORTER B(0)AT1 (Homosapiens) | 5 / 12 | LEU C 52ALA C 204LEU C 482LEU C 485GLY C 490 | 1.36A | 20.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6nb6 | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | ALA C 284ILE C 272LEU C 52ARG C 48GLY C 270 | 1.18A | 16.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6nb6 | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | LEU A 843ALA A 997TYR A 989LEU A 941GLY A 839 | 1.39A | 16.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_A_9TPA601_1 (SERUM ALBUMIN) | 6nb8 | S230 ANTIGEN-BINDING(FAB) FRAGMENT,HEAVY CHAIN (Homosapiens) | 5 / 12 | LEU H 86ARG H 16PRO H 14LEU H 11GLY H 8 | 1.54A | 18.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6nur | NSP12 (SARSr-CoV) | 5 / 12 | LEU A 460ALA A 252TYR A 175ILE A 171LEU A 131 | 1.42A | 20.27 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9Q_B_9TPB601_1 (SERUM ALBUMIN) | 6vw1 | ACE2 (Homosapiens) | 5 / 12 | LEU A 558ALA A 532HIS A 401LEU A 570GLY A 399 | 1.44A | 20.67 | None |