Ligand ID: 7V7


Drugbank ID:
DB00813
(Fentanyl)


Indication:
For the treatment of cancer patients with severe pain that breaks through their regular narcotic therapy.

Get human targets for 7V7 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '7V7' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		1ssk NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
VAL A 111
ALA A 116
PRO A  45
TYR A  65
ALA A 112
1.66A20.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ARG B 298
PRO B   9
TYR A 118
0.85A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ARG B 298
PRO B   9
TYR A 118
1.00A22.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ARG A 298
PRO A   9
TYR B1118
1.50A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		3 / 3
ARG A 298
PRO A   9
TYR B 118
1.14A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
SER C 262
VAL C 277
ALA C 293
ALA C 294
GLY C 261
1.58A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
LEU C 282
PHE C 314
ALA C 293
TYR C 295
GLY C 260
1.45A20.69
GOL  C1011 (-4.1A)
GOL  C1005 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
LEU G 122
VAL G 136
ALA G 115
TYR H  76
GLY G 118
1.67A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ajf SPIKE PROTEIN
(SARSr-CoV)		5 / 12
LEU E 412
VAL E 498
TRP E 423
ALA E 422
TRP E 340
1.62A21.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ajf ACE2
(Homo
sapiens)		5 / 12
LEU A 558
PHE A 315
SER A 545
ALA A 532
ALA A 550
1.59A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
ARG A 298
PRO A   9
TYR A 154
1.34A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER G 319
ALA H 274
TRP H 302
ALA G 314
GLY G 317
1.73A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 8
THR C 264
TYR C 269
THR C 266
GLN C 268
1.57A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L 182
SER L 194
TRP L 187
ALA L 151
GLY L 153
1.63A22.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
VAL H  37
ALA H  60
TYR L  96
TYR L  36
GLY H  49
1.57A24.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU H  45
SER H  35
VAL H  37
ALA H  60
GLY H  49
1.51A24.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  35
THR L 102
TYR L  87
GLN L  37
1.64A22.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
LEU A 101
PHE A 133
ALA A 112
TYR A 114
GLY A  79
1.41A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
SER C  81
VAL C  96
ALA C 112
ALA C 113
GLY C  80
1.63A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
SER D 197
TYR C 442
PRO C 459
ALA D 183
GLY D 196
1.56A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 8
TRP D  47
THR C 433
TYR C 484
THR C 486
1.26A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 8
TRP B 331
THR B 333
ARG A 320
GLN B 282
1.72A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 8
THR A 192
TYR A 193
THR A 195
GLN A 196
1.65A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2idy NSP3
(SARSr-CoV)		5 / 12
LEU A  36
SER A  84
VAL A  62
ALA A  55
ALA A  59
1.37A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		4 / 8
THR A 201
TYR A 239
THR A 198
GLN A 192
1.67A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ofz NUCLEOCAPSID PROTEIN
(SARS-COV
Tor2)		5 / 12
VAL A  73
PRO A  81
TYR A 113
ALA A 135
GLY A  70
1.77A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 8
THR A 192
TYR A 193
THR A 195
GLN A 196
1.74A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
TYR A 118
THR A  26
ARG C  10
GLN A  19
1.40A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
LEU A 141
SER B   1
TRP B 207
ALA B 210
TYR A 118
1.66A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
ARG B  90
PRO B  93
TYR C  32
1.00A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
PHE A 149
ALA A  79
TYR A  47
ALA A  72
GLY A  73
1.49A21.48
SAH  A1293 (-4.6A)
None
SAH  A1293 (-4.8A)
None
SAH  A1293 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
PHE A 149
ALA A  79
TYR A  47
ALA A  72
GLY A  73
1.49A21.75
SAH  A1300 (-4.5A)
None
None
None
SAH  A1300 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ARG A 298
PRO A   9
TYR B 118
1.22A24.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3bgf F26G19 FAB
(Mus
musculus)		4 / 8
TRP L  35
THR L 102
TYR L  87
GLN L  37
1.67A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
TRP A 461
TYR A 454
THR A 453
ARG A 514
1.69A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU F 412
VAL F 498
TRP F 423
ALA F 422
TRP F 340
1.62A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU A 558
PHE A 315
SER A 545
ALA A 532
ALA A 550
1.64A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU F 412
VAL F 498
TRP F 423
ALA F 422
TRP F 340
1.65A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3d0i SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU F 412
VAL F 498
TRP F 423
ALA F 422
TRP F 340
1.64A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
THR A  62
ARG A  55
GLN C  20
TRP C  53
1.57A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 141
SER A   1
TYR B 126
TYR B 118
GLY A   2
1.56A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
PHE A 149
ALA A  79
TYR A  47
ALA A  72
GLY A  73
1.49A20.12
SAM  A 302 ( 4.8A)
None
SAM  A 302 (-4.5A)
None
SAM  A 302 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3sci SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU E 412
VAL E 498
TRP E 423
ALA E 422
TRP E 340
1.68A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3scj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU E 412
VAL E 498
TRP E 423
ALA E 422
TRP E 340
1.69A20.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
THR B 517
TYR B 516
THR B 453
ARG B 460
1.74A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
LEU B 554
VAL B 404
ALA B 396
TYR B 385
GLY B 399
1.68A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU E 412
VAL E 498
TRP E 423
ALA E 422
TRP E 340
1.64A20.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ARG A 298
PRO A   9
TYR B 118
1.19A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
LEU D 117
PHE D 111
SER D 112
VAL D 115
GLY D 114
1.58A16.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
LEU C 117
PHE C 111
SER C 112
VAL C 115
GLY C 114
1.58A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
ARG A 476
PRO A 451
TYR A 447
1.02A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR C 300
THR C 302
ARG A 747
GLN C 301
1.63A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU C1045
PHE C1044
VAL C1043
ALA C1038
GLY C1041
1.70A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL C 420
ALA C 384
TYR C 410
PRO C 399
TRP C 340
1.63A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE A 262
SER A 279
VAL A 276
PRO A  61
ALA A 284
1.56A20.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
LEU C 597
SER C 303
VAL C 581
TYR C 622
GLY C 579
1.50A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
PHE B 764
SER B 712
VAL B 763
ALA B1002
ALA B1004
1.78A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
SER A 676
TYR B 928
PRO B 903
TYR B 932
GLY A 675
1.78A8.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
THR A 943
TYR A 989
THR A 988
GLN B 987
1.62A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
VAL B 611
TYR B 632
TYR B 606
GLY B 578
1.62A8.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
THR B 431
TYR B 484
ARG B 426
GLN B 492
1.38A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE C 262
SER C 279
VAL C 276
PRO C  61
ALA C 284
1.48A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ack ACE2
(Homo
sapiens)		5 / 12
LEU D 554
VAL D 404
ALA D 396
TYR D 385
GLY D 399
1.60A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU A 412
VAL A 498
ALA A 422
TRP A 340
TYR A 410
1.49A10.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE B 262
VAL B 276
TRP B 619
PRO B  61
ALA B 284
1.75A11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
LEU A1045
PHE A1044
VAL A1043
ALA A1038
GLY A1041
1.70A11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE A 262
SER A 279
VAL A 276
PRO A  61
ALA A 284
1.52A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
TYR C 989
THR C 943
ARG A 747
GLN A 744
1.36A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
LEU B 412
VAL B 498
TRP B 423
ALA B 422
TRP B 340
1.47A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
ARG C 449
PRO C 450
TYR A 195
1.66A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6cs2 ACE2
(Homo
sapiens)		5 / 12
LEU D 320
SER D 545
VAL D 318
ALA D 532
ALA D 550
1.47A14.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens;
SARSr-CoV)		5 / 12
LEU C   8
VAL A 152
ALA A 149
TYR A 116
ALA A 150
1.69A4.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6jyt HELICASE
(SARSr-CoV)		5 / 12
LEU A 391
SER A 385
VAL A 387
ALA A 379
TYR A 398
1.65A14.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6m0j ACE2
(Homo
sapiens)		4 / 8
TRP A 461
TYR A 454
THR A 453
ARG A 514
1.61A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
ARG A  14
PRO A   9
TYR A 509
1.48A14.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
TRP A 176
TYR A 139
THR A 404
ARG A 328
1.72A14.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
THR A 943
TYR A 989
THR A 988
GLN C 987
1.69A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU B1045
PHE B1044
VAL B1043
ALA B1038
GLY B1041
1.68A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		3 / 3
ARG L  50
PRO L  64
TYR L  91
1.27A23.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6nur NSP12
(SARSr-CoV)		5 / 12
PHE A 753
VAL A 776
ALA A 772
TYR A 748
ALA A 771
1.60A10.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6nus NSP12
(SARSr-CoV)		5 / 12
PHE A 753
VAL A 776
ALA A 772
TYR A 748
ALA A 771
1.60A10.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6vw1 ACE2
(Homo
sapiens)		4 / 8
TRP A 461
TYR A 454
THR A 453
ARG A 514
1.63A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
TRP L  35
THR L 102
TYR L  87
GLN L  37
1.68A21.54
None
None
None
SO4  L 302 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
LEU L  46
SER H  99
TRP H  33
TYR L  36
GLY H  97
1.46A21.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
LEU L  46
TRP H  33
TYR L  96
TYR L  36
GLY H  97
1.60A21.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
TRP L  35
THR L 102
TYR L  87
GLN L  37
1.69A21.54
None
None
None
SO4  L 302 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
TRP L  35
THR L 102
TYR L  87
GLN L  37
1.65A21.54
None
None
None
SO4  L 302 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
LEU H  80
PHE H  63
VAL H  67
TYR H  90
GLY H  65
1.63A25.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6xhn 3C-LIKE PROTEINASE
(SARSr)		3 / 3
ARG A 298
PRO A   9
TYR A 154
1.23A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6xhn 3C-LIKE PROTEINASE
(SARSr)		3 / 3
ARG B 298
PRO B   9
TYR A 118
1.29A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		6xhn 3C-LIKE PROTEINASE
(SARSr)		3 / 3
ARG A 298
PRO A   9
TYR B 118
1.28A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU B  81
PHE B  64
VAL B  68
TYR B  94
GLY B  66
1.61A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU H  81
PHE H  64
VAL H  68
TYR H  94
GLY H  66
1.61A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.73A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU C  52
SER B 103
TRP B  33
TYR C  42
GLY B 101
1.58A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.71A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
SER H 103
TRP H  33
TYR L  42
GLY H 101
1.56A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.72A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.76A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
TRP H  33
TYR L 102
TYR L  42
GLY H 101
1.57A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU C  52
TRP B  33
TYR C 102
TYR C  42
GLY B 101
1.56A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
SER H 103
TRP H  33
TYR L  42
GLY H 101
1.54A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L   4
PHE L  77
SER L  58
TYR L  97
ALA L  40
1.66A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.78A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
TRP H  33
TYR L 102
TYR L  42
GLY H 101
1.67A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
LEU H  81
PHE H  64
VAL H  68
TYR H  94
GLY H  66
1.56A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
SER H 103
TRP H  33
TYR L  42
GLY H 101
1.55A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU C  52
TRP B  33
TYR C 102
TYR C  42
GLY B 101
1.56A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
LEU H  81
PHE H  64
VAL H  68
TYR H  94
GLY H  66
1.62A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU L  52
TRP H  33
TYR L 102
TYR L  42
GLY H 101
1.56A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
LEU B  81
PHE B  64
VAL B  68
TYR B  94
GLY B  66
1.61A21.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.76A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 12
LEU C  52
SER B 103
TRP B  33
TYR C  42
GLY B 101
1.56A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.74A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.76A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP C  41
THR C 108
TYR C  93
GLN C  43
1.73A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TRP L  41
THR L 108
TYR L  93
GLN L  43
1.73A21.19
None