Ligand ID: 4AP


Drugbank ID:
DB06637
(Dalfampridine)


Indication:
Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS).

Get human targets for 4AP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '4AP' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY B1011
LYS B1012
GLY B1015
LEU B1032
1.28A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
GLY A 183
GLY A 174
MET A 165
LEU A 167
1.25A22.51
None
None
None
CY6  A1145 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
GLY A 299
THR A 266
GLY B 228
ASP B 230
1.12A22.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
THR A  68
GLY A  71
LEU A  66
ASP A  64
1.49A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
GLY A 116
LYS A 114
GLY A   1
LEU A  66
0.69A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
HIS A   2
GLY A 116
GLY A 116
LEU A 112
0.95A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
HIS A   2
GLY A 116
GLY A 116
LEU A  66
1.18A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gtb 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A  11
LYS A  12
GLY A  15
LEU A  30
1.14A22.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2gx4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A  11
LYS A  12
GLY A  15
LEU A  30
1.07A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
GLY B 183
GLY B 174
MET B 165
LEU B 167
1.17A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A 183
GLY A 174
MET A 165
LEU A 167
1.26A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A  11
LYS A  12
GLY A  15
LEU A  30
1.12A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS B 378
GLY B 399
GLY B 395
ASP B 382
1.19A19.80
 ZN  B 901 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A 183
GLY A 174
MET A 165
LEU A 167
1.11A23.08
None
None
959  A 350 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A  11
LYS A  12
GLY A  15
LEU A  32
1.09A22.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3i6l HLA, A-24
(Homo
sapiens)		4 / 8
GLY D 107
GLY D   1
LEU D 179
ASP D  29
1.24A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY B  11
LYS B  12
GLY B  15
LEU B  30
1.27A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A 183
GLY A 174
MET A 165
LEU A 167
1.19A22.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A  11
LYS A  12
GLY A  15
LEU A  30
1.16A22.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS B 378
GLY B 399
GLY B 395
ASP B 382
1.16A19.80
 ZN  B 901 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLY A 183
GLY A 174
MET A 165
LEU A 167
1.24A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		4 / 6
SER A 116
VAL A 166
GLY B  76
GLY A 164
1.42A20.92
 NA  A 402 (-2.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 8
GLY D   6
THR D 103
GLY C   2
LEU D  54
1.25A19.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
GLY D   6
THR D 103
GLY O   2
LEU D  54
1.24A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER C1033
VAL C1047
GLY C1026
GLY C1028
1.13A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
SER B1033
VAL B1047
GLY B1026
GLY B1028
1.41A12.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
SER A 440
VAL A 584
GLY A 578
GLY A 610
1.24A10.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER A1033
VAL A1047
GLY A1026
GLY A1028
1.19A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6acj ACE2
(Homo
sapiens)		4 / 8
HIS D 401
GLY D 399
GLY D 395
ASP D 382
1.20A19.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
SER C1012
VAL B1022
GLY B1026
GLY B1028
1.08A12.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
HIS A1030
GLY A1026
GLY A1028
LEU A1031
1.26A12.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
SER B1012
VAL A1022
GLY A1026
GLY A1028
1.17A12.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
GLY A 285
GLY A 282
LEU A 461
ASP A 458
1.24A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
SER C 288
VAL C 441
GLY C 434
GLY C 285
1.04A16.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
GLY C 115
THR C 121
GLY C 284
LEU C 494
1.28A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER B1012
VAL C1022
GLY C1026
GLY C1028
1.29A12.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6nur NSP12
(SARSr-CoV)		4 / 6
SER A 681
VAL A 662
GLY A 559
GLY A 683
1.27A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6vw1 ACE2
(Homo
sapiens)		4 / 8
HIS B 378
GLY B 399
GLY B 395
ASP B 382
1.20A19.97
 ZN  B 703 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
SER H 180
SER H 153
VAL H 152
GLY H 139
1.79A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS C 204
LYS C 151
THR C 203
LEU C 207
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER L  25
SER L  28
VAL L  29
GLY L  72
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
LYS L 151
THR L 203
LEU L 207
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER H 183
SER L 137
VAL L 139
GLY H 143
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
SER B 190
SER B 131
GLY B 137
GLY B 138
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER B 183
SER C 137
VAL C 139
GLY B 143
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
SER H 184
SER H 157
VAL H 156
GLY H 143
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
SER B 184
SER B 157
VAL B 156
GLY B 143
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
SER H 184
SER H 157
VAL H 156
GLY H 143
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER H 183
SER L 137
VAL L 139
GLY H 143
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER L  25
SER L  28
VAL L  29
GLY L  72
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
HIS C 204
LYS C 151
THR C 203
LEU C 207
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
SER B 183
SER C 137
VAL C 139
GLY B 143
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
SER C  25
SER C  28
VAL C  29
GLY C  72
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
LYS L 151
THR L 203
LEU L 207
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
SER H 183
SER L 137
VAL L 139
GLY H 143
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
SER B 184
SER B 157
VAL B 156
GLY B 143
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
SER L  25
SER L  28
VAL L  29
GLY L  72
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
SER H 184
SER H 157
VAL H 156
GLY H 143
1.78A
None