Ligand ID: 308


Drugbank ID:
DB00915
(Amantadine)


Indication:
For the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.

Get human targets for 308 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '308' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 9
GLY A 138
SER B  -1
LEU A 141
SER B   1
GLY B   2
1.55A5.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 6
SER B 121
ALA B 116
SER B 123
SER B 147
1.50A6.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
VAL A 114
SER A 147
SER A 144
SER A 123
1.35A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU F 930
LEU E 930
ILE E1160
ALA D 926
0.93A11.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 6
LEU K  44
LEU I  48
ILE H   2
ILE H   5
ALA G  40
1.54A6.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU L  33
LEU L  36
ILE K   5
ILE G   5
0.97A4.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 9
SER E  19
SER A  24
LEU E  27
LEU D  19
SER A  19
1.59A18.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		1zvb E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 6
LEU B  20
LEU A  20
ILE C  16
SER A  17
ALA A  15
1.63A5.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 8
ALA E 157
SER E 156
ALA E 107
SER A  59
1.23A8.74
None
None
None
GOL  E2001 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 8
SER A  59
ALA E 157
SER E 156
ALA E 107
1.23A19.44
GOL  E2001 ( 4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2beq SPIKE GLYCOPROTEIN
(SARSr)		4 / 6
LEU D1182
LEU D1185
ILE D1180
ILE F1180
1.31A6.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
SER C 919
SER A 924
LEU C 927
LEU E1168
SER A 919
1.55A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 6
ALA G 312
SER G 311
ALA H 309
SER G 319
1.24A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 8
ALA C 314
SER C 311
ALA D 255
ALA D 274
1.22A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 9
ILE E 321
SER E 313
LEU F 292
SER E 319
GLY F 285
1.60A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 181
SER H 179
ALA L 176
SER L 177
1.57A5.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 8
SER B 140
ALA B 130
SER B 129
ALA B  39
ALA B 125
1.66A12.50
None
APR  B 477 (-3.5A)
APR  B 477 (-4.4A)
APR  B 477 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr)		4 / 6
LEU C 161
LEU C 138
SER C 140
ALA C 130
1.22A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 9
SER B 129
GLY B 131
ILE B 132
LEU B 161
SER B 140
1.58A12.50
APR  B 477 (-4.4A)
APR  B 477 (-3.4A)
APR  B 477 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
ALA B  87
SER B  86
ALA B 154
SER B  79
1.36A7.12
 BR  B 319 (-4.0A)
BR  B 319 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
SER T  15
SER W  15
ALA W  18
SER W  11
1.35A10.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 6
ALA A  65
SER A  67
SER A  63
ALA A  65
1.04A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 9
GLY A  83
ILE A  84
LEU A  45
SER A  89
LEU A  50
1.03A14.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 6
LEU D 179
LEU D 205
ILE D 207
ALA D 216
1.07A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 6
SER D 224
SER D 160
ALA D 157
SER D 199
1.22A8.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 6
SER D 224
SER D 160
SER D 199
SER D 163
1.56A7.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2gib NUCLEOCAPSID PROTEIN
(SARSr)		4 / 6
ALA A 312
SER A 311
ALA B 309
SER A 319
1.33A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2gib NUCLEOCAPSID PROTEIN
(SARSr)		4 / 6
ALA B 312
SER B 311
ALA A 309
SER B 319
1.30A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2gri NSP3
(SARSr)		4 / 6
LEU A  66
LEU A  80
SER A  84
ALA A  59
1.05A12.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 9
GLY A 253
LEU A 263
SER A 261
LEU A 254
GLY A 238
1.55A5.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 6
LEU A 119
ILE A  79
ILE A  99
ALA A 108
0.88A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		4 / 6
LEU A  58
LEU A  80
ILE A  65
ILE A   7
1.32A10.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 6
SER B 121
ALA B 116
SER B 123
SER B 147
1.52A5.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU D 119
ILE D  79
ILE D  99
ALA D 108
0.61A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
SER B   1
GLY A 170
SER A 144
SER A 139
GLY A 138
1.52A6.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
GLY B 253
LEU B 263
SER B 261
LEU B 254
GLY B 238
1.58A5.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU D 119
ILE D  79
ILE D  99
ALA D 108
0.90A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
ALA E  22
ALA E   6
SER E   1
SER A   1
1.29A5.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2w2g NSP3
(SARSr)		4 / 6
LEU B 603
LEU B 627
ILE B 608
ILE B 592
0.98A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		2w2g NSP3
(SARSr-CoV)		5 / 9
SER B 451
ILE B 449
SER B 435
LEU B 429
LEU B 413
1.54A8.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2w2g NSP3
(SARSr)		4 / 6
LEU A 603
LEU A 627
ILE A 608
ILE A 592
0.98A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr)		4 / 6
LEU A 153
ILE A 157
ILE A 167
ALA A 168
1.15A18.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 6
LEU A  85
ILE A  68
SER A 129
ILE A 127
ALA A 168
1.46A17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		3atw 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY A 174
ILE A 136
SER A 147
LEU A  86
GLY A 149
1.60A6.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3bgf F26G19 FAB
(Mus
musculus)		4 / 6
SER L  72
SER L  63
ALA L  51
SER L  52
1.18A9.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
SER L  65
ILE L  48
SER L  20
LEU L  33
SER L  63
1.41A6.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ALA B  46
SER B  47
SER B  43
ALA B  65
1.21A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
SER B 411
SER B 545
ALA B 550
SER B 547
1.43A4.24
None
NDG  B 619 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		3e9s NSP3
(SARSr-CoV)		4 / 6
ALA A  87
SER A  86
ALA A 154
SER A  79
1.35A6.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.58A6.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY A 120
SER A 139
SER A 123
SER A 144
GLY A 146
1.50A6.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
SER B 121
SER B 144
LEU B 115
SER B 123
GLY B  29
1.50A6.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		3i6k BETA-2-MICROGLOBULIN
(Homo
sapiens)		4 / 6
LEU F  54
LEU F  64
ILE F  35
SER F  28
1.04A10.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3i6l HLA, A-24
(Homo
sapiens)		4 / 6
SER D  38
SER D  11
ALA D  24
SER D   9
1.49A8.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		3sci ACE2
(Homo
sapiens)		4 / 6
ALA B  46
SER B  47
SER B  43
ALA B  65
1.19A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3sci ACE2
(Homo
sapiens)		4 / 6
SER A 411
SER A 545
ALA A 550
SER A 547
1.50A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ALA A  46
SER A  47
ALA A  65
SER A  40
1.33A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
SER A 411
SER A 545
ALA A 550
SER A 547
1.40A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.56A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 9
GLY B  47
ILE B  44
SER A 246
LEU A 217
GLY A 210
1.47A18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		4 / 6
ALA B  87
SER B  86
ALA B 154
SER B  79
1.32A7.12
None
DMS  B 905 ( 4.4A)
None
DMS  B 905 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 6
ALA A 166
SER A 167
ALA A 115
SER A 247
1.33A7.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 6
LEU A 170
LEU A 120
ILE A 152
ILE A 117
ALA A 115
1.78A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.50A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.49A5.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
VAL B 167
SER B 171
ALA B 225
SER B 230
1.36A3.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
VAL B 167
SER B 171
ALA B 225
SER B 230
1.17A3.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5dus ORF1A
(MERS-CoV)		4 / 6
LEU A  41
ILE A  90
ILE A  51
ALA A  48
1.34A15.56
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		5e6j REPLICASE
POLYPROTEIN 1AB
UBIQUITIN
(SARSr-CoV;
synthetic
construct)		5 / 9
GLY E  47
ILE E  44
SER D 246
LEU D 217
GLY D 210
1.31A18.64
5MW  E  48 ( 2.4A)
5MW  E  48 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5f22 NSP8
NSP7
(SARSr-CoV)		4 / 8
ALA B 107
SER A  59
ALA B 157
SER B 156
1.25A13.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		5ko3 ORF1A
(MERS-CoV)		4 / 6
ALA A 166
SER A 167
ALA A 115
SER A 247
1.33A8.11
None
None
CME  A 111 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 6
VAL B  29
SER B  28
ALA N  71
SER N  72
1.41A3.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU A 597
LEU A 636
ILE A 656
ALA A 654
1.04A17.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		5x4r S PROTEIN
(MERS-CoV)		4 / 6
ALA A 138
ALA A 309
SER A 133
SER A 135
1.32A5.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5x4r S PROTEIN
(MERS-CoV)		4 / 6
SER A 133
SER A 135
ALA A 138
SER A 137
1.40A6.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		5x59 S PROTEIN
(MERS-CoV)		5 / 8
SER A1091
SER A1089
SER A 845
ALA A1096
SER A1095
1.56A2.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		5x59 S PROTEIN
(MERS-CoV)		5 / 9
GLY C 615
SER A1050
LEU C 638
LEU C 651
GLY C 613
1.49A1.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5x59 S PROTEIN
(MERS-CoV)		4 / 6
SER A 133
SER A 135
ALA A 138
SER A 137
1.40A2.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
SER C  36
LEU C 209
SER C 211
LEU C 182
GLY C  39
1.55A2.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ALA C 250
SER C 248
SER C  95
SER C 173
1.29A2.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
SER B 173
ALA B 250
SER B 248
SER B  95
1.31A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		5x5c S PROTEIN
(MERS-CoV)		4 / 6
ALA A 138
ALA A 309
SER A 133
SER A 135
1.32A2.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5x5f S PROTEIN
(MERS-CoV)		5 / 6
LEU A 415
ILE A 573
SER A 429
ILE A 433
ALA A 434
1.58A17.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 6
LEU A 959
LEU B 959
ILE C 955
SER B 957
ALA B 954
1.45A9.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER A 703
ALA C 872
SER A1052
SER A 701
1.30A1.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU C 776
SER A 686
ILE A 687
ALA A 688
1.03A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6acg ACE2
(Homo
sapiens)		5 / 9
SER D 128
GLY D 130
SER D 507
SER D 124
GLY D 173
1.52A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
SER C 964
ALA C 971
ALA C 954
SER C 956
1.28A1.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
SER A 105
GLY A 104
ILE A 228
SER B 456
GLY A 225
1.55A1.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
VAL A 458
SER A 456
SER C 105
SER C 111
1.37A1.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ILE B 228
SER B 113
ILE B 226
ALA B 127
1.07A17.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ALA C 866
ALA C 875
SER B 686
SER C 861
1.22A1.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
SER C  36
LEU C 209
SER C 211
LEU C 182
GLY C  39
1.42A1.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
SER A 673
SER A 659
ALA A 658
ALA A 595
1.17A1.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
VAL C 290
SER C 289
SER C 292
ALA C 284
1.42A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6cs2 ACE2
(Homo
sapiens)		5 / 9
SER D 124
ILE D 126
LEU D 176
SER D 128
GLY D 130
1.40A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6cs2 ACE2
(Homo
sapiens)		4 / 6
ALA D  46
SER D  47
SER D  43
ALA D  65
1.37A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6jyt HELICASE
(SARSr-CoV)		4 / 8
SER A 289
ALA A 312
SER A 310
ALA A 308
1.23A3.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6lzg ACE2
(Homo
sapiens)		4 / 6
ALA A  46
SER A  47
SER A  43
ALA A  65
1.27A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 9
GLY A  51
SER A 314
LEU A 234
LEU A 427
SER A 278
1.59A3.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m18 ACE2
(Homo
sapiens)		4 / 6
SER D 411
SER D 545
ALA D 550
SER D 547
1.43A2.75
None
NAG  D 910 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6m18 ACE2
(Homo
sapiens)		4 / 6
ALA D 550
SER D 547
ALA D 533
SER D 411
1.17A2.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 6
LEU C 238
ILE C 319
SER C 323
ILE C 251
ALA C 247
1.60A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
VAL C 441
SER C 100
ALA C 282
SER C 118
1.45A3.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6m1d ACE2
(Homo
sapiens)		5 / 6
LEU B 628
LEU B 624
ILE B 679
SER B 623
ILE B 622
1.76A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
GLY A 653
ILE A 656
SER A 582
LEU C 843
GLY A 634
1.55A1.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
VAL B 663
SER B 673
ALA B 658
SER B 659
1.47A1.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
SER C 673
SER C 659
ALA C 658
ALA C 595
1.19A1.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		5 / 8
SER H 129
ALA H 128
SER H 126
ALA H 124
ALA H  10
1.73A7.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAD_A_308A1_1
(TRANSMEMBRANE
PEPTIDE OF MATRIX
PROTEIN 2)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 9
SER L  70
ILE L  53
SER L  20
LEU L  38
SER L  68
1.57A10.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6nur NSP7
NSP8
(SARSr-CoV)		4 / 8
ALA D 152
SER D 151
ALA D 102
SER C  54
1.28A8.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6nus NSP12
(SARSr-CoV)		5 / 6
LEU A 638
LEU A 575
ILE A 579
ILE A 589
ALA A 688
1.40A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
ALA H 136
SER H 130
SER H 187
SER H 132
1.76A7.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
SER L 215
SER H 130
ALA H 136
ALA H 125
1.76A9.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
ALA H  71
SER H  55
SER H  70
ALA H  78
1.70A7.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
VAL L 133
SER L 176
ALA H 168
SER H 177
1.39A9.38
None
GOL  L 301 (-3.1A)
None
GOL  L 301 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
SER H 128
SER H 130
ALA H 136
SER L 215
1.65A7.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
SER H 187
SER H 132
ALA H 136
SER H 130
1.69A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
VAL L 133
SER L 131
SER H 179
SER H 177
1.57A9.38
None
None
GOL  L 301 (-3.5A)
GOL  L 301 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
LEU L  78
SER L  14
ILE L 106
ALA L  12
1.43A13.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
SER H 132
ALA H 136
SER H 130
SER H 187
1.68A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
SER H 130
ALA H 136
ALA H 125
SER L 215
1.76A11.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
SER H 132
SER H 130
ALA H 136
SER H 128
1.66A7.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
VAL L 133
SER L 131
SER H 179
SER H 177
1.61A9.38
None
None
GOL  L 301 (-3.5A)
GOL  L 301 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ALA H 125
SER L 215
SER H 130
ALA H 136
1.76A11.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
LEU L  47
LEU L  73
ILE L  75
ALA L  84
1.19A13.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
VAL L 133
SER L 177
SER H 177
SER L 162
1.71A9.38
None
None
GOL  L 301 (-3.1A)
GOL  L 301 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
VAL L 133
SER L 177
SER H 177
SER L 162
1.71A9.38
None
None
GOL  L 301 (-3.1A)
GOL  L 301 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
LEU H  80
ILE H  69
ILE H  51
ALA H  71
1.68A13.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQT_C_308C1_1
(M2 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ALA H 136
ALA H 125
SER L 215
SER H 130
1.76A11.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL B 173
SER C 168
SER B 183
SER C 182
1.66A7.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER C 137
SER B 183
SER B 181
1.71A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.57A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C  29
SER C  25
SER C  28
SER C  73
1.69A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER B 183
SER C 182
SER B 181
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL B 173
SER C 168
SER B 183
SER C 182
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ALA B  72
SER B  56
SER B  71
ALA B  79
1.70A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER B 181
ALA B 172
SER B 183
SER C 182
1.34A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.74A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.71A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
LEU C  53
LEU C  79
ILE C  81
ALA C  90
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER B 183
SER C 182
SER B 181
1.61A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER C 137
SER B 183
SER B 181
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER H 181
ALA H 172
SER H 183
SER L 182
1.34A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
LEU L  53
LEU L  79
ILE L  81
ALA L  90
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL C  29
SER C  25
SER C  28
SER C  73
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.68A7.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
ALA H  72
SER H  56
SER H  71
ALA H  79
1.69A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
SER H 181
ALA H 172
SER H 183
SER L 182
1.34A7.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.68A7.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.71A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER H 181
SER L 182
SER H 183
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 6
LEU L  53
LEU L  79
ILE L  81
ALA L  90
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER H 181
SER L 182
SER H 183
1.72A7.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.70A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
ALA H  72
SER H  56
SER H  71
ALA H  79
1.67A7.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.58A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
LEU L  53
LEU L  79
ILE L  81
ALA L  90
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C  29
SER C  25
SER C  28
SER C  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
SER H 181
ALA H 172
SER H 183
SER L 182
1.33A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UIV_H_308H1008_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
LEU C  53
LEU C  79
ILE C  81
ALA C  90
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.67A7.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ALA B  72
SER B  56
SER B  71
ALA B  79
1.69A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER C 137
SER B 183
SER B 181
1.71A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
ALA H  72
SER H  56
SER H  71
ALA H  79
1.69A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C9J_B_308B101_1
(PROTON CHANNEL
PROTEIN M2,
TRANSMEMBRANE
SEGMENT)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
SER B 181
ALA B 172
SER B 183
SER C 182
1.34A7.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER B 183
SER C 182
SER B 181
1.58A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL B 173
SER C 168
SER B 183
SER C 182
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L  29
SER L  25
SER L  28
SER L  73
1.75A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER H 183
SER L 182
SER H 181
1.57A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER B 183
SER C 182
SER B 181
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL H 173
SER L 168
SER H 183
SER L 182
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C  29
SER C  25
SER C  28
SER C  73
1.74A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_F_308F101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL C 139
SER C 137
SER B 183
SER B 181
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL L 139
SER L 137
SER H 183
SER H 181
1.70A17.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKK_B_308B101_0
(MATRIX PROTEIN 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 6
VAL B 173
SER C 168
SER B 183
SER C 182
1.68A7.61
None