 |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'R9UQ53'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FOF_F_MFXF0_1 (DNA TOPOISOMERASE 4SUBUNIT A) | Moxifloxacin | 4njl | S PROTEIN (MERS-CoV) | 2 / 3 | GLY A1045SER A1041 | 0.30A | 15.89 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QHF_A_ACTA502_0 (CHORISMATE SYNTHASE) | Acetic acid | 4njl | S PROTEIN (MERS-CoV) | 3 / 3 | GLY A1066ASP A1059SER A1064 | 1.42A | 14.93 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XK8_A_PQNA844_1 (PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1) | Phylloquinone | 4njl | S PROTEIN (MERS-CoV) | 4 / 7 | PHE A1012SER A1268ALA A1275LEU A1276 | 1.37A | 12.39 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PYM_A_1UNA1001_3 (PROTEASE RETROPEPSIN) | Nelfinavir | 4njl | S PROTEIN (MERS-CoV) | 3 / 3 | ASP A1024ASN A1028THR A1257 | 1.25A | 19.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1I9G_A_SAMA301_0 (HYPOTHETICAL PROTEINRV2118C) | S-Adenosylmethionine | 4njl | S PROTEIN (MERS-CoV) | 5 / 12 | ILE A1047GLY A1052ALA A1046ASP A1059LEU A1058 | 1.21A | 17.27 | NoneNonePGE A2001 ( 4.7A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NU4_B_478B401_2 (PROTEASE) | Amprenavir | 4njl | S PROTEIN (MERS-CoV) | 5 / 9 | LEU A1058ASP A1059GLY A1066ILE A1246ILE A1055 | 1.41A | 20.00 | None |