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SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'Q6RCZ9'

	DrReposER ID / Desc.	Drug	Hit PDBID	Hit Macromolecule	Res. Matches	View	Interface	RMSD	Seq. Identity (%)	HETATM	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	Spermine	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 7		ASN A 203 GLU A 290 TYR A 239 GLU A 240	1.72A	17.82	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_B_PFNB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	Fenoprofen	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 4		TYR A  54 LEU A  58 LEU A  57 HIS A  41	1.65A	23.04	None None None D3F  A 307 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0F_B_B49B9001_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR)	Sunitinib	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 10		ALA A 173 TYR A 182 GLY A 149 CYH A 145 PHE A 140	1.49A	19.71	None None None D3F  A 307 (-4.3A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XWF_A_ADNA433_2 (ADENOSYLHOMOCYSTEINA SE)	Adenosine	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3		THR A  24 GLU A  47 HIS A  41	1.16A	21.09	None None D3F  A 307 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI8_B_HNQB255_1 (CATHEPSIN B)	Nitroxoline	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 6		GLY A 149 HIS A 163 HIS A 164 CYH A 145	1.42A	21.82	None None D3F  A 307 (-4.4A) D3F  A 307 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	Eplerenone	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 6		GLN A 189 CYH A  85 THR A 175 PHE A 181	1.69A	20.53	D3F  A 307 ( 4.7A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F7F_A_NIOA602_1 (NICOTINATE PHOSPHORIBOSYLTRANSF ERASE, PUTATIVE)	Niacin	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 5		HIS A  41 ILE A  43 PRO A  52 ASP A  48	1.79A	20.68	D3F  A 307 (-3.4A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZY_A_CE3A1103_1 (DNA CROSS-LINK REPAIR 1A PROTEIN)	Cefotaxime	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 8		THR A  98 PRO A  96 VAL A  73 GLY A  71	1.12A	22.19	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI8_A_HNQA255_1 (CATHEPSIN B)	Nitroxoline	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 7		GLY A 149 HIS A 163 HIS A 164 CYH A 145	1.46A	21.82	None None D3F  A 307 (-4.4A) D3F  A 307 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CCV_C_RFPC1205_1 (-)	Rifampicin	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 12		GLN A 192 ASP A 187 ARG A 188 ARG A  40 HIS A 164	1.63A	13.63	D3F  A 307 (-3.2A) None None None D3F  A 307 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCE_A_RITA602_2 (CYTOCHROME P450 3A4)	Ritonavir	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 6		ARG A  40 ARG A  88 PHE A  66 THR A  35	1.63A	21.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SN0_B_T44B602_1 (TRANSTHYRETIN)	Levothyroxine	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 7		LEU A 242 GLU A 240 ALA A 234 LEU A 272	1.05A	16.45	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FML_A_RTLA401_0 (RETINOL DEHYDRATASE)	Vitamin A	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 12		TYR A  54 HIS A  41 HIS A 164 LEU A  86 PHE A 181	1.61A	18.65	None D3F  A 307 (-3.4A) D3F  A 307 (-4.4A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0F_A_B49A9001_1 (MAST/STEM CELL GROWTH FACTOR RECEPTOR)	Sunitinib	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 11		ALA A 173 TYR A 182 GLY A 149 CYH A 145 PHE A 140	1.48A	19.71	None None None D3F  A 307 (-4.3A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	Halofuginone	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 12		LEU A 272 GLU A 240 HIS A 246 THR A 111 GLY A 109	1.53A	19.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	Afatinib	2gz7	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 7		ILE A  43 TYR A  54 PRO A  52 HIS A  41	1.39A	21.41	None None None D3F  A 307 (-3.4A)