 |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'Q6RCY8'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DPD_B_SAMB601_0 (PROTEIN LYSINEMETHYLTRANSFERASE 1) | S-Adenosylmethionine | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 6 / 12 | TYR A 101LEU A 87SER A 81TRP A 31VAL A 68VAL A 20 | 1.68A | 18.74 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_1 (TYROSINE-PROTEINKINASE ABL1) | Imatinib | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 4 / 7 | VAL A 212ILE A 281GLY A 109ALA A 206 | 1.10A | 21.49 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZRF_D_EVPD101_1 () | Etoposide | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 4 / 5 | GLY A 215ASP A 216GLN A 299MET A 6 | 1.72A | 17.92 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2B9E_A_SAMA1201_0 (NOL1/NOP2/SUN DOMAINFAMILY, MEMBER 5ISOFORM 2) | S-Adenosylmethionine | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 5 / 12 | GLY A 179ASN A 84LYS A 180LEU A 32ARG A 88 | 1.32A | 22.65 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2NYU_A_SAMA201_0 (PUTATIVE RIBOSOMALRNAMETHYLTRANSFERASE 2) | S-Adenosylmethionine | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 5 / 12 | GLY A 146GLY A 174ALA A 173LEU A 30LEU A 177 | 1.49A | 20.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BXO_B_SAMB238_0 (N,N-DIMETHYLTRANSFERASE) | S-Adenosylmethionine | 2gz9 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 5 / 12 | GLY A 138LEU A 115MET A 165SER A 144TYR A 118 | 1.60A | 22.85 | None |