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SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'P0DTD2'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FI0_B_TRPB1001_0 (TRYPTOPHANYL-TRNASYNTHETASE) | L-Tryptophan | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 8 | VAL B 96ILE B 44VAL B 15VAL B 76 | 1.03A | 17.35 | None15P B 100 ( 4.5A)None15P B 100 ( 4.6A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FL9_G_TOPG200_1 (DIHYDROFOLATEREDUCTASE (DHFR)) | Trimethoprim | 6z4u | PROTEIN 9B (SARS-CoV-2) | 5 / 12 | LEU A 21LEU B 54VAL B 76ILE B 44LEU B 46 | 1.26A | 22.50 | None15P B 100 ( 4.0A)15P B 100 ( 4.6A)15P B 100 ( 4.5A)15P B 100 ( 4.9A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FM6_D_BRLD503_2 (PEROXISOMEPROLIFERATORACTIVATED RECEPTORGAMMA) | Rosiglitazone | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 4 | ILE A 19LEU B 52VAL B 94ILE B 44 | 1.39A | 18.18 | None15P B 100 (-4.0A)None15P B 100 ( 4.5A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FL9_B_TOPB200_1 (DIHYDROFOLATEREDUCTASE (DHFR)) | Trimethoprim | 6z4u | PROTEIN 9B (SARS-CoV-2) | 5 / 12 | LEU A 21LEU B 54VAL B 76ILE B 44LEU B 46 | 1.30A | 22.50 | None15P B 100 ( 4.0A)15P B 100 ( 4.6A)15P B 100 ( 4.5A)15P B 100 ( 4.9A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IEN_A_VDYA201_2 (CDL2.2) | Calcidiol | 6z4u | PROTEIN 9B (SARS-CoV-2) | 5 / 12 | ILE B 44LEU B 46VAL A 96ILE A 44LEU A 46 | 1.09A | 19.40 | 15P B 100 ( 4.5A)15P B 100 ( 4.9A)None15P B 100 ( 4.8A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9K_A_TYLA2200_1 (CREB-BINDING PROTEIN) | Acetaminophen | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 6 | VAL B 94LEU B 46ILE B 44VAL A 94 | 1.17A | 20.83 | None15P B 100 ( 4.9A)15P B 100 ( 4.5A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RG7_A_MTXA161_2 (DIHYDROFOLATEREDUCTASE) | Methotrexate | 6z4u | PROTEIN 9B (SARS-CoV-2) | 3 / 3 | ILE B 19ILE B 44THR A 24 | 1.23A | 20.81 | None15P B 100 ( 4.5A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FI0_B_TRPB1001_0 (TRYPTOPHANYL-TRNASYNTHETASE) | L-Tryptophan | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 8 | VAL A 96ILE A 44VAL A 15VAL A 76 | 0.89A | 17.35 | None15P B 100 ( 4.8A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_A_ANWA601_0 (RHODOPSIN KINASE) | Amlexanox | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 7 | LEU A 87ILE A 5VAL A 93ALA B 57 | 1.37A | 11.69 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BJW_B_SVRB512_2 (PHOSPHOLIPASE A2) | Suramin | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 7 | VAL B 23ILE A 44ARG A 13LEU A 81 | 1.27A | 20.97 | None15P B 100 ( 4.8A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3HJO_B_EAAB211_1 (GLUTATHIONES-TRANSFERASE P) | Etacrynic acid | 6z4u | PROTEIN 9B (SARS-CoV-2) | 4 / 8 | VAL B 94VAL A 96ILE B 19VAL B 76 | 1.33A | 18.57 | NoneNoneNone15P B 100 ( 4.6A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RG7_A_MTXA161_2 (DIHYDROFOLATEREDUCTASE) | Methotrexate | 6z4u | PROTEIN 9B (SARS-CoV-2) | 3 / 3 | ILE A 19ILE A 44THR B 24 | 1.11A | 20.81 | None15P B 100 ( 4.8A)None |