SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'P0DTC7'

DrReposER ID / Desc. Drug Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
PHE A  31
PHE A  50
GLY A  27
LEU A  41
PHE A  39
1.56A10.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		Trifluoperazine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  41
PHE A  39
LEU A  62
PHE A  50
1.35A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		S-Adenosylmethionine6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  24
GLU A  18
ASP A  36
1.39A15.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		Nicotine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  31
PHE A  50
GLY A  27
PHE A  39
1.52A10.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		Dopamine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  41
PHE A  48
LEU A  62
PRO A  19
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  48
PHE A  50
ALA A  40
THR A  13
1.61A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		Paroxetine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  49
TYR A  60
PHE A  31
SER A  29
GLY A  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  39
PHE A  48
HIS A  32
VAL A  14
1.71A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		Camphor6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
THR A  46
LEU A  62
VAL A  14
THR A  12
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  34
THR A  13
ALA A  40
VAL A  14
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  16
SER A  29
VAL A   9
GLY A  11
1.57A11.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		Ribavirin6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  12
HIS A   4
LEU A  16
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
HIS A  32
PHE A  48
THR A  13
THR A  42
1.41A15.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
GLU A  26
GLY A  27
THR A  24
PHE A  50
1.40A13.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
GLU A   7
THR A  12
VAL A  14
ALA A  64
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		Nicotinamide6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLY A  23
ALA A  49
LYS A  57
GLU A  26
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
ARG A  63
SER A  45
TYR A   5
1.64A21.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		4-Androstenedione6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 9
PHE A  31
LEU A  62
ALA A  40
LEU A  41
PHE A  48
1.79A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
SER A  29
LEU A  41
TYR A  25
LEU A  16
1.48A10.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		Lobeglitazone6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
HIS A  58
PHE A  48
PHE A  39
LEU A  62
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		L-Leucine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
THR A  42
THR A  13
VAL A  14
HIS A  32
1.79A8.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LEU A  16
LYS A  38
ALA A  40
1.42A3.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		Piracetam6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
SER A  21
GLY A  23
PRO A  19
ASN A  37
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		Methotrexate6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  16
LEU A  62
PHE A  44
SER A  45
THR A  12
1.50A8.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		Novobiocin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  44
ARG A  10
ARG A  63
LEU A  62
1.71A14.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		Paroxetine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  49
TYR A  60
VAL A  59
PHE A  31
GLY A  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		Aminocaproic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
GLY A  55
VAL A  56
PRO A  53
GLY A  23
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.37A13.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		Bosutinib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLU A  18
GLY A  23
ALA A  49
TYR A  60
ASP A  54
1.56A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		Duloxetine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  49
TYR A  60
PHE A  31
SER A  29
GLY A  27
1.53A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		Nevirapine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  16
LYS A  38
TYR A  25
LEU A  41
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
GLU A   7
LEU A  62
LEU A  16
LEU A  41
1.48A9.09

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.70A14.57

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		Aminocaproic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
GLY A  55
PRO A  53
GLY A  23
GLU A  18
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		Etravirine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  41
ASN A  28
TYR A  60
GLY A  27
LEU A  62
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  48
PHE A  50
ALA A  40
THR A  13
1.62A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PRO A  19
PRO A  53
GLY A  23
LEU A   2
1.62A16.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		Zonisamide6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
TYR A  60
LEU A  41
PHE A  39
TYR A  25
1.35A8.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
VAL A  14
PHE A  39
LEU A  62
THR A  46
1.68A15.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		Estriol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
TYR A  60
PHE A  48
PHE A  31
ALA A  40
1.71A10.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLU A   7
THR A  12
VAL A  14
ALA A  64
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		4-Androstenedione6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  31
ALA A  40
LEU A  41
PHE A  48
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		Cocaine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
HIS A   4
LEU A  16
LEU A   2
GLU A  18
1.80A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
GLY A  27
SER A  29
PHE A  44
LEU A  41
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_A_CHDA103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 8
LEU A  16
LEU A  41
GLU A   7
ALA A  64
LEU A  62
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		Trifluoperazine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  48
PHE A  31
LEU A  34
PHE A  50
1.40A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		Novobiocin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  44
ARG A  10
ARG A  63
LEU A  62
1.67A14.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
SER A  66
TYR A   5
VAL A   9
ALA A  64
SER A  45
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		Fluvoxamine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
ALA A  49
TYR A  60
PHE A  31
SER A  29
GLY A  27
1.62A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		Brinzolamide6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
GLN A   6
PHE A  48
LEU A  41
THR A  42
THR A  13
1.64A15.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.32A13.36

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		Methotrexate6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  16
LEU A  62
PHE A  44
SER A  45
THR A  12
1.65A8.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LYS A  38
ALA A  40
LEU A  41
1.69A3.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		Piracetam6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PRO A  19
ASN A  37
SER A  21
GLY A  23
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  13
ALA A  40
LYS A  38
1.45A11.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
SER A  66
TYR A   5
VAL A   9
ALA A  64
SER A  45
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
SER A  29
PHE A  31
PHE A  39
PHE A  48
1.67A11.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  13
ALA A  40
LYS A  38
1.48A11.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
TYR A  25
GLY A  27
HIS A  32
SER A  29
1.66A15.38

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		Tiotropium6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  12
THR A  13
PHE A  44
1.75A8.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		Ribavirin6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  12
HIS A   4
LEU A  16
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		Trifluoperazine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  34
LEU A  15
PHE A  31
SER A  29
1.57A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		Estrone6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  41
THR A  42
LEU A  34
LEU A  15
LEU A  16
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LEU A  16
LYS A  38
ALA A  40
1.40A3.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  50
PHE A  48
TYR A  25
HIS A  32
1.59A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		Lobeglitazone6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLU A   1
PHE A  48
PHE A  39
LEU A  41
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		Adenosine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLU A  26
ALA A  49
VAL A  59
TYR A   3
GLU A   1
1.34A9.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  39
PHE A  48
HIS A  32
VAL A  14
1.71A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		Acetylsalicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
GLU A  18
GLY A  23
THR A  24
1.72A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  39
PHE A  48
THR A  46
LEU A  62
1.52A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
PHE A  48
LEU A  41
1.69A14.57
17.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  16
LYS A  38
ALA A  40
LEU A  34
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		Trifluoperazine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  48
PHE A  31
LEU A  34
PHE A  50
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		Losartan6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  44
ASN A  28
PRO A  19
PHE A  48
1.68A8.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
SER A  66
TYR A   5
VAL A   9
ALA A  64
SER A  45
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		Tiotropium6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  13
THR A  12
PHE A  44
1.51A8.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LEU A  16
LYS A  38
ALA A  40
1.43A3.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		Dasatinib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  16
VAL A  14
THR A  46
TYR A  60
SER A  29
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
GLU A  26
GLY A  27
THR A  24
PHE A  50
1.41A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		Mefenamic acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
SER A  66
TYR A   5
VAL A   9
ALA A  64
SER A  45
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		Amlexanox6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
ALA A  64
VAL A  14
THR A  12
THR A  42
1.75A19.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		Pemetrexed6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  64
LEU A  62
THR A  13
LEU A  16
LEU A  41
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.65A14.57

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		Paroxetine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  49
TYR A  60
PHE A  31
SER A  29
GLY A  27
1.51A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		Phenylbutazone6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.69A13.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		Abiraterone6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
ALA A  49
SER A  21
GLY A  23
ALA A  51
1.29A8.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
PHE A  48
LEU A  41
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		4-Androstenedione6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 9
PHE A  31
LEU A  62
ALA A  40
LEU A  41
PHE A  48
1.77A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  39
PHE A  48
TYR A  25
HIS A  32
1.54A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		4-Androstenedione6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  31
ALA A  40
LEU A  41
PHE A  48
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		Methotrexate6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  16
LEU A  62
PHE A  44
SER A  45
THR A  12
1.69A8.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		Econazole6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 9
PHE A  39
TYR A  25
LEU A  62
LEU A  16
ALA A  40
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
GLN A   6
LEU A  41
THR A  42
THR A  13
1.62A15.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		Sorafenib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  64
LEU A  16
LEU A  34
HIS A  32
PHE A  31
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
LEU A  16
LEU A  41
GLU A   7
ALA A  64
LEU A  62
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		Phenylbutazone6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 8
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		Clindamycin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
TYR A  60
GLU A  18
PHE A  48
SER A  29
1.79A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.28A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		Remikiren6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  11
SER A  45
THR A  46
VAL A  14
SER A  29
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		Camphor6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  39
TYR A  25
THR A  46
VAL A  14
1.40A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		Efavirenz6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
LEU A  41
ASN A  28
TYR A  60
GLY A  27
LEU A  62
1.67A8.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		Posaconazole6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PRO A  30
PRO A  33
PHE A  39
LEU A  34
1.48A13.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.29A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LYS A  38
ALA A  40
LEU A  41
LEU A  34
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
LEU A  62
SER A  45
PHE A  44
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.58A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		Nicotine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  31
PHE A  50
GLY A  27
PHE A  39
1.46A10.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  15
THR A  12
LEU A  16
VAL A   9
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
LEU A  16
LEU A  41
GLU A   7
ALA A  64
LEU A  62
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
TYR A  25
GLY A  27
HIS A  32
SER A  29
1.63A15.38

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		Salicylic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLU A   7
THR A  12
VAL A  14
ALA A  64
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
GLU A  26
GLY A  27
THR A  24
PHE A  50
1.31A13.36

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
LEU A  16
LEU A  41
GLU A   7
ALA A  64
LEU A  62
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		Doxycycline6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
HIS A  32
PHE A  31
THR A  13
VAL A  14
LEU A  62
1.56A14.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		Adenosine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
VAL A  59
PHE A  50
LEU A  41
PHE A  48
GLY A  27
1.54A10.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		Chloramphenicol6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
PHE A  50
TYR A  25
LEU A  62
PHE A  44
PHE A  39
1.62A15.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		Vitamin A6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
PHE A  48
THR A  12
LEU A  16
1.44A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  16
PHE A  39
TYR A  25
LEU A  62
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		Nevirapine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  41
TYR A  60
GLY A  27
LEU A  62
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		Salmeterol6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
ASP A  54
SER A  22
SER A  21
1.60A8.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		Ticagrelor6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 8
SER A  29
TYR A  25
GLY A  27
ALA A  64
PHE A  48
1.74A16.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		S-Adenosylmethionine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  40
HIS A  58
TYR A  60
CSS A  52
CSS A  20
1.72A13.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		Pyridoxal6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
SER A  21
THR A  24
GLY A  55
ASP A  54
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		Nevirapine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
LEU A  41
ASN A  28
TYR A  60
GLY A  27
LEU A  62
1.74A8.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
HIS A  32
SER A  29
TYR A  25
GLY A  27
1.66A15.38

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  31
PHE A  39
PHE A  50
ALA A  49
1.65A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		Thiamine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PRO A  19
PHE A  44
LEU A  62
SER A  29
1.76A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LYS A  38
ALA A  40
LEU A  41
1.67A3.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		Estrone6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLN A   6
TYR A  60
LEU A  41
THR A  13
1.68A15.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		Estrone6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
GLN A   6
TYR A  60
LEU A  41
THR A  12
1.68A15.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
SER A  66
TYR A   5
VAL A   9
ALA A  64
SER A  45
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
GLU A  26
GLY A  27
THR A  24
PHE A  50
1.39A13.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		Nicotinamide6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
HIS A   4
TYR A   3
LYS A  57
GLU A   1
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		Tiotropium6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
THR A  13
THR A  42
PHE A  39
1.50A8.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  48
PHE A  50
ALA A  40
THR A  13
1.62A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  39
PHE A  48
TYR A  25
HIS A  32
1.53A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
GLU A  26
GLY A  27
THR A  24
PHE A  50
1.36A13.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		Nevirapine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  41
TYR A  60
GLY A  27
LEU A  62
1.30A8.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
LEU A  16
LEU A  41
GLU A   7
ALA A  64
LEU A  62
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		Nicotinamide6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
PHE A  44
LEU A  62
PHE A  48
LEU A  41
SER A  29
1.78A14.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		Bortezomib6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
THR A  42
THR A  13
SER A  45
HIS A  32
SER A  29
1.79A14.75

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		Camphor6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  39
TYR A  25
THR A  46
VAL A  14
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		Methotrexate6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
LEU A  16
LEU A  62
PHE A  44
SER A  45
THR A  12
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		Duloxetine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
ALA A  49
TYR A  60
PHE A  31
SER A  29
GLY A  27
1.50A7.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.35A13.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		Trifluoperazine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
PHE A  48
PHE A  31
LEU A  34
PHE A  50
1.39A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		Nicotinamide6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
PHE A  44
LEU A  62
PHE A  48
LEU A  41
SER A  29
1.80A14.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		Icosapent6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  41
PHE A  48
PRO A  33
PHE A  50
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		Pentostatin6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
LEU A  62
LEU A  15
PHE A  48
1.17A12.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		Levoleucovorin6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
GLY A  27
LEU A  16
VAL A  14
ALA A  49
SER A  45
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		Benzoic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
GLY A  23
ALA A  51
PHE A  50
ALA A  49
VAL A  56
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		Nevirapine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 11
LEU A  41
ASN A  28
TYR A  60
GLY A  27
LEU A  62
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		Nicotinamide6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
HIS A   4
TYR A   3
LYS A  57
GLU A   1
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		4-Androstenedione6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 9
PHE A  31
LEU A  62
ALA A  40
LEU A  41
PHE A  48
1.76A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		Niacin6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
THR A  24
PHE A  50
GLU A  26
GLY A  27
1.37A13.36

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		Lumiracoxib6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
LEU A  15
THR A  12
LEU A  16
VAL A   9
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		Oxamniquine6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 12
VAL A  59
LEU A  41
PHE A  50
LEU A  62
THR A  46
1.76A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		Dopamine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
GLU A   7
ARG A  65
ALA A  64
TYR A   5
1.76A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		Acetic acid6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
LEU A  62
GLU A   7
SER A  45
1.77A13.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		Parachlorophenol6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 6
PHE A  39
PHE A  50
TYR A  60
HIS A  58
1.67A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		Cholic Acid6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 7
LEU A  62
GLN A  61
LEU A  41
PHE A  39
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		Lisinopril6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
ALA A  40
THR A  13
PHE A  31
0.98A8.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		Pilocarpine6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 8
PHE A  48
PHE A  50
ALA A  40
THR A  13
1.61A10.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		Colfosceril palmitate6w37 PROTEIN 7A
(SARS-CoV-2)		4 / 5
LEU A  34
LYS A  38
ALA A  40
LEU A  41
1.70A3.42
None