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SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'P0DTC3'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KP6_A_SALA3002_1 (TRANSCRIPTIONALREGULATOR TCAR) | Salicylic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 8 | VAL A 50LEU A 53VAL B 88LEU B 53 | 0.85A | 19.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C9O_A_CAMA423_0 (CYTOCHROME P450) | Camphor | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ILE B 167THR B 164GLY A 172VAL A 225ILE B 232 | 1.34A | 20.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OCU_A_TYLA3001_1 (LACTOTRANSFERRIN) | Acetaminophen | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | LEU B 95TYR B 91GLY B 49 | 0.95A | 20.85 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C9L_A_CAMA1419_0 (CYTOCHROME P450) | Camphor | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ILE B 167THR B 164GLY A 172VAL A 225ILE B 232 | 1.33A | 20.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DSG_A_0HKA1201_2 (MUSCARINICACETYLCHOLINERECEPTORM4,ENDOLYSIN,ENDOLYSIN,MUSCARINICACETYLCHOLINERECEPTOR M4) | Tiotropium | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ASN A 82LEU B 53PHE A 87 | 1.07A | 21.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C9O_A_CAMA423_0 (CYTOCHROME P450) | Camphor | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ILE A 167THR A 164GLY B 172VAL B 225ILE A 232 | 1.33A | 20.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1H1D_A_SAMA301_0 (CATECHOL-O-METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN B 144GLY A 187TYR B 145ASN A 161TYR B 189 | 1.38A | 19.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGR_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL A 201TYR A 212GLN A 213 | 1.45A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNX_A_T3A502_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE B 118MET B 125ARG B 126 | 1.19A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGT_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL B 201TYR B 212GLN B 213 | 1.44A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NU4_B_478B401_2 (PROTEASE) | Amprenavir | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 9 | LEU A 203GLY B 188ILE A 169GLY A 188ILE A 167 | 1.48A | 16.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DSG_A_0HKA1201_2 (MUSCARINICACETYLCHOLINERECEPTORM4,ENDOLYSIN,ENDOLYSIN,MUSCARINICACETYLCHOLINERECEPTOR M4) | Tiotropium | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ASN B 82LEU A 53PHE B 87 | 1.14A | 21.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5K4P_A_SORA611_0 (PROBABLEPHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-1) | Sorbitol | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | GLY A 224THR A 223SER B 216TYR B 215 | 1.29A | 20.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WZ1_C_SAMC601_0 (NS5METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | GLY B 174GLY B 172GLU B 226ASP A 238VAL A 237 | 1.42A | 20.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ETE_B_H3PB552_1 (GLUTAMATEDEHYDROGENASE) | Hexachlorophene | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | TYR B 145TYR B 212ILE B 167 | 1.50A | 19.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGK_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL B 201TYR B 212GLN B 213 | 1.43A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XIW_B_LOCB504_1 (TUBULIN ALPHA-1BCHAINTUBULIN BETA CHAIN) | Colchicine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | SER B 40ALA B 98VAL B 97 | 1.14A | 19.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNW_A_T3A501_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE A 118MET A 125ARG A 126 | 1.19A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UA5_A_06XA501_1 (CYTOCHROME P450 2B6) | Amlodipine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 8 | ILE B 47SER B 58LEU A 108VAL A 112 | 1.39A | 20.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNW_A_T3A501_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE B 62MET A 125ARG A 126 | 1.30A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGK_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL A 201TYR A 212GLN A 213 | 1.43A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WZ1_C_SAMC601_0 (NS5METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | GLY A 174GLY A 172GLU A 226ASP B 238VAL B 237 | 1.42A | 20.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NU4_B_478B401_2 (PROTEASE) | Amprenavir | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 9 | LEU B 203GLY A 188ILE B 169GLY B 188ILE B 167 | 1.48A | 16.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WZ1_D_SAMD601_0 (NS5METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | GLY A 174GLY A 172GLU A 226ASP B 238VAL B 237 | 1.42A | 20.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WZ1_D_SAMD601_0 (NS5METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | GLY B 174GLY B 172GLU B 226ASP A 238VAL A 237 | 1.42A | 20.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VRJ_A_1KXA301_1 (HLA CLASS IHISTOCOMPATIBILITYANTIGEN, B-57 ALPHACHAIN10-MER PEPTIDE) | Abacavir | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | TYR A 184TYR A 156TYR A 160THR A 151ILE A 167 | 1.43A | 20.835.77 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3N8Y_A_DIFA701_1 (PROSTAGLANDIN G/HSYNTHASE 1) | Diclofenac | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 11 | VAL A 88LEU A 46ILE B 47GLY B 49ALA B 51 | 1.35A | 18.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OCU_A_TYLA3001_1 (LACTOTRANSFERRIN) | Acetaminophen | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | LEU A 95TYR A 91GLY A 49 | 0.98A | 20.85 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KP6_A_SALA3002_1 (TRANSCRIPTIONALREGULATOR TCAR) | Salicylic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 8 | VAL B 50LEU B 53VAL A 88LEU A 53 | 0.85A | 19.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ETE_B_H3PB552_1 (GLUTAMATEDEHYDROGENASE) | Hexachlorophene | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | TYR A 233TYR A 160ILE A 186 | 1.03A | 19.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C9L_A_CAMA1419_0 (CYTOCHROME P450) | Camphor | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ILE A 167THR A 164GLY B 172VAL B 225ILE A 232 | 1.33A | 20.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5K4P_A_SORA611_0 (PROBABLEPHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-1) | Sorbitol | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | GLY B 224THR B 223SER A 216TYR A 215 | 1.29A | 20.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2JN3_A_JN3A131_2 (FATTY ACID-BINDINGPROTEIN, LIVER) | Ursodeoxycholic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | ASN A 144GLN B 185ILE B 158PHE B 146 | 1.30A | 17.61 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DSG_A_0HKA1201_2 (MUSCARINICACETYLCHOLINERECEPTORM4,ENDOLYSIN,ENDOLYSIN,MUSCARINICACETYLCHOLINERECEPTOR M4) | Tiotropium | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ASN A 82LEU B 53PHE A 56 | 1.30A | 21.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2CL5_A_SAMA1217_0 (CATECHOLO-METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN B 144GLY A 187TYR B 145ASN A 161TYR B 189 | 1.41A | 19.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ETE_B_H3PB552_1 (GLUTAMATEDEHYDROGENASE) | Hexachlorophene | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | TYR A 145TYR A 212ILE A 167 | 1.50A | 19.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNX_A_T3A502_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE A 118MET A 125ARG A 126 | 1.19A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2JN3_A_JN3A131_2 (FATTY ACID-BINDINGPROTEIN, LIVER) | Ursodeoxycholic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | ASN B 144GLN A 185ILE A 158PHE A 146 | 1.29A | 17.61 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1H1D_A_SAMA301_0 (CATECHOL-O-METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN A 144GLY B 187TYR A 145ASN B 161TYR A 189 | 1.39A | 19.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ETE_B_H3PB552_1 (GLUTAMATEDEHYDROGENASE) | Hexachlorophene | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | TYR B 233TYR B 160ILE B 186 | 1.02A | 19.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGT_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL A 201TYR A 212GLN A 213 | 1.44A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNX_A_T3A502_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE B 62MET A 125ARG A 126 | 1.27A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5QGR_A_ACTA301_0 (PEROXISOMAL COENZYMEA DIPHOSPHATASENUDT7) | Acetic acid | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | VAL B 201TYR B 212GLN B 213 | 1.45A | 21.31 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HLP_A_GAWA1501_0 (SUBSTANCE-PRECEPTOR,SUBSTANCE-PRECEPTOR) | Netupitant | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN B 234ILE B 167ILE B 169ILE B 186PHE A 230 | 1.43A | 18.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3N8Y_A_DIFA701_1 (PROSTAGLANDIN G/HSYNTHASE 1) | Diclofenac | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 11 | VAL B 88LEU B 46ILE A 47GLY A 49ALA A 51 | 1.37A | 18.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FPJ_A_SAMA301_1 (PUTATIVEUNCHARACTERIZEDPROTEIN) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | TYR A 233GLY A 196GLU A 194GLU A 181 | 1.40A | 21.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HLP_A_GAWA1501_0 (SUBSTANCE-PRECEPTOR,SUBSTANCE-PRECEPTOR) | Netupitant | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN A 234ILE A 167ILE A 169ILE A 186PHE B 230 | 1.43A | 18.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LNX_A_T3A502_2 (THYROID HORMONERECEPTOR ALPHA) | Liothyronine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ILE A 62MET B 125ARG B 126 | 1.27A | 21.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VRJ_A_1KXA301_1 (HLA CLASS IHISTOCOMPATIBILITYANTIGEN, B-57 ALPHACHAIN10-MER PEPTIDE) | Abacavir | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | TYR B 184TYR B 156TYR B 160THR B 151ILE B 167 | 1.44A | 20.835.77 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2CL5_A_SAMA1217_0 (CATECHOLO-METHYLTRANSFERASE) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | ASN A 144GLY B 187TYR A 145ASN B 161TYR A 189 | 1.41A | 19.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RRZ_A_LURA705_1 (PROSTAGLANDIN G/HSYNTHASE 2) | Lumiracoxib | 6xdc | PROTEIN 3A (SARS-CoV-2) | 5 / 12 | LEU A 85VAL B 50GLY B 49ALA B 51LEU A 108 | 1.43A | 20.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FPJ_A_SAMA301_1 (PUTATIVEUNCHARACTERIZEDPROTEIN) | S-Adenosylmethionine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 4 / 6 | TYR B 233GLY B 196GLU B 194GLU B 181 | 1.40A | 21.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DSG_A_0HKA1201_2 (MUSCARINICACETYLCHOLINERECEPTORM4,ENDOLYSIN,ENDOLYSIN,MUSCARINICACETYLCHOLINERECEPTOR M4) | Tiotropium | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | ASN B 82LEU A 53PHE B 56 | 1.37A | 21.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5JSD_B_1GNB618_1 (PHIAB6 TAILSPIKE) | Glucosamine | 6xdc | PROTEIN 3A (SARS-CoV-2) | 3 / 3 | THR A 164SER A 166TYR A 212 | 1.27A | 18.03 | None |