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SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'A0A6C0N6C6'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5E5J_A_017A201_3 (PROTEASE) | Darunavir | 7jtl | NONSTRUCTURALPROTEIN NS8 (SARS-CoV-2) | 3 / 3 | ASP A 34VAL A 116LEU A 118 | 1.05A | 19.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KQY_B_017B101_2 (PROTEASE E35D-DRV) | Darunavir | 7jtl | NONSTRUCTURALPROTEIN NS8 (SARS-CoV-2) | 4 / 7 | GLY B 50ALA B 51ASP A 119ILE B 58 | 1.28A | 17.21 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B52_A_OAQA302_0 (SULFOTRANSFERASE) | Oxamniquine | 7jtl | NONSTRUCTURALPROTEIN NS8 (SARS-CoV-2) | 5 / 12 | PRO A 38VAL A 114PHE A 108SER A 103LEU A 98 | 1.34A | 15.56 | None |