SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'A0A0D3MU51'

DrReposER ID / Desc. Drug Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		Darunavir6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 9
ALA C 367
ASP C 366
ILE C 365
GLY C 286
ILE C 306
1.31A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_A_ECNA411_1
(FLAVOHEMOGLOBIN)		Econazole6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ILE D 306
ALA B 313
LEU D 361
ILE D 365
1.17A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		Acetic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
TYR B 337
ASN D 355
LEU D 358
1.17A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		Pantothenic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
ARG A 279
PHE A 288
PHE C 322
ILE A 306
1.42A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		4-Androstenedione6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PHE A 322
ALA C 307
ALA C 310
ALA A 313
THR A 312
1.36A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		Acetic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
TYR D 337
ASN B 355
LEU B 358
1.20A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FOF_F_MFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A)		Moxifloxacin6g13 NUCLEOPROTEIN
(MERS-CoV)		2 / 3
GLY C 318
SER C 314
0.33A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ARG D 261
PHE D 270
GLY D 297
THR D 298
1.41A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		Acetic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
TYR C 337
ASN A 355
LEU A 358
1.17A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 4
ASN B 364
GLY B 289
ASP A 290
ASP B 300
1.24A13.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ARG C 261
PHE C 270
GLY C 297
THR C 298
1.36A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
LEU A 360
GLN A 305
LYS D 263
1.34A13.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		Isoniazid6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ARG A 302
GLY A 297
GLN A 292
LEU A 293
0.96A10.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_A_ECNA411_1
(FLAVOHEMOGLOBIN)		Econazole6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ILE B 306
ALA D 313
LEU B 361
ILE B 365
1.16A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NDV_1_PAR13413_1
(25S RIBOSOMAL RNA
5S RIBOSOMAL RNA)		Paromomycin6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
LYS A 356
GLU A 359
LYS D 263
1.12A11.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		Isoniazid6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ARG A 302
GLY A 297
GLN A 292
LEU A 293
0.97A10.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_A_ANWA601_0
(RHODOPSIN KINASE)		Amlexanox6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
LEU C 339
ILE A 365
LEU A 360
ALA A 310
1.36A12.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ARG A 261
PHE A 270
GLY A 297
THR A 298
1.34A12.10
None
TMO  A 402 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		Deoxycholic Acid6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PRO A 301
LEU A 296
ALA D 313
SER D 314
MET D 317
1.20A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_A_ECNA411_1
(FLAVOHEMOGLOBIN)		Econazole6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ILE C 306
ALA A 313
LEU C 361
ILE C 365
1.17A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		Pantothenic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
ARG D 279
PHE D 288
PHE B 322
ILE D 306
1.45A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		Darunavir6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 9
ALA B 367
ASP B 366
ILE B 365
GLY B 286
ILE B 306
1.36A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		4-Androstenedione6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PHE C 322
ALA A 307
ALA A 310
ALA C 313
THR C 312
1.36A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
ILE A 306
LEU C 339
LEU A 309
ASN A 294
ASP A 290
1.50A16.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		Acetic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
TYR A 337
ASN C 355
LEU C 358
1.16A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		Raltitrexed6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE D 276
ASP D 290
LEU D 293
GLY D 289
1.25A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		4-Androstenedione6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PHE D 322
ALA B 307
ALA B 310
ALA D 313
THR D 312
1.35A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		Raltitrexed6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE B 276
ASP B 290
LEU B 293
GLY B 289
1.20A19.42
None
CL  B 402 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_A_ECNA411_1
(FLAVOHEMOGLOBIN)		Econazole6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
ILE A 306
ALA C 313
LEU A 361
ILE A 365
1.28A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
HIS D 262
GLU B 308
ASN B 351
1.48A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
TYR C 354
ASP A 330
HIS A 326
1.11A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		Darunavir6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 9
ALA A 367
ASP A 366
ILE A 365
GLY A 286
ILE A 306
1.37A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		Raltitrexed6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE C 276
ASP C 290
LEU C 293
GLY C 289
1.23A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
HIS A 262
SER C 314
SER A 266
PHE A 276
1.32A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		Deoxycholic Acid6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PRO A 301
LEU A 296
GLN A 363
ALA D 313
SER D 314
1.33A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
HIS A 262
GLU C 308
ASN C 351
1.47A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		Phylloquinone6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE A 322
ARG A 340
ALA C 344
LEU A 339
1.30A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		Darunavir6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 9
ALA D 367
ASP D 366
ILE D 365
GLY D 286
ILE D 306
1.31A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		Pantothenic acid6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
ARG C 279
PHE C 288
PHE A 322
ILE C 306
1.45A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
ALA A 344
GLN C 327
THR C 325
1.17A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		S-Adenosylmethionine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
HIS C 262
GLU A 308
ASN A 351
1.48A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
THR D 298
ASN A 287
PHE A 288
0.92A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		4-Androstenedione6g13 NUCLEOPROTEIN
(MERS-CoV)		5 / 12
PHE B 322
ALA D 307
ALA D 310
ALA B 313
THR B 312
1.38A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		Adenosine6g13 NUCLEOPROTEIN
(MERS-CoV)		3 / 3
THR D 265
GLU A 359
HIS D 262
1.35A14.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		Raltitrexed6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE A 276
ASP A 290
LEU A 293
GLY A 289
1.23A19.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		Phylloquinone6g13 NUCLEOPROTEIN
(MERS-CoV)		4 / 7
PHE B 322
ARG B 340
ALA D 344
LEU B 339
1.34A9.92
None