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| PDB ID: 6xip Macromolecule: NSP8 Source Organism: SARS-CoV-2 Gene names: - UniProt ID: - |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO PDBID '6xip'
1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.| DrReposER ID / Desc. | Drug | Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WDM_A_ADNA901_1 (4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE) | Adenosine | 5 / 9 | GLY D 113LEU C 60ASN C 69ASN D 109ILE D 106 | 1.50A | 19.08 | NoneNoneNoneEDO D 202 (-3.6A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5T8H_B_478B401_1 (PROTEASE) | Amprenavir | 5 / 12 | LEU D 103ALA D 150VAL D 130ILE D 119ILE D 106 | 0.94A | 19.05 | NoneEDO D 201 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XIW_B_LOCB504_1 (TUBULIN ALPHA-1BCHAINTUBULIN BETA CHAIN) | Colchicine | 3 / 3 | SER C 26ALA C 30VAL C 33 | 1.24A | 11.50 | NoneEDO C 101 (-3.5A)EDO C 101 ( 4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLYSTREPTAVIDIN) | L-Valine | 3 / 3 | TYR D 138SER D 173TRP D 182 | 1.06A | 20.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1DF7_A_MTXA501_1 (DIHYDROFOLATEREDUCTASE) | Methotrexate | 5 / 12 | ILE D 106ALA D 110LEU D 91VAL C 16LEU C 13 | 1.17A | 17.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3E22_B_LOCB700_1 (TUBULIN ALPHA-1CCHAINTUBULIN BETA-2BCHAIN) | Colchicine | 3 / 3 | SER C 26ALA C 30VAL C 33 | 0.96A | 11.08 | NoneEDO C 101 (-3.5A)EDO C 101 ( 4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FT9_A_CHDA131_0 (FATTY ACID-BINDINGPROTEIN 2, LIVER) | Cholic Acid | 5 / 11 | LEU C 13LEU C 17ILE D 106MET C 62LEU C 71 | 1.40A | 21.01 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZV2_A_LEVA801_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 1) | Lenvatinib | 3 / 3 | LYS B 79LEU D 153ASP D 143 | 1.17A | 18.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2NYR_B_SVRB401_1 (NAD-DEPENDENTDEACETYLASESIRTUIN-5) | Suramin | 5 / 12 | ALA D 126ALA D 152ALA D 150TYR D 149LEU C 35 | 1.50A | 16.61 | NoneEDO D 201 ( 4.0A)EDO D 201 (-3.7A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VC0_A_RITA602_1 (CYTOCHROME P450 3A4) | Ritonavir | 5 / 12 | LEU B 103ILE A 39PHE A 49ALA A 48ALA A 0 | 1.23A | 12.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2BYO_A_LNLA1217_1 (LIPOPROTEIN LPPX) | Alpha-Linolenic Acid | 4 / 4 | VAL A 66LEU A 28ILE B 119LEU A 55 | 1.44A | 19.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_0 (TYROSINE-PROTEINKINASE ABL1) | Imatinib | 5 / 12 | ILE D 132VAL D 115LEU C 60ALA D 110ASP D 112 | 1.24A | 18.15 | NoneNoneNoneNoneEDO D 202 (-4.1A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FBM_B_RTLB951_2 (PROTEIN (CARTILAGEOLIGOMERIC MATRIXPROTEIN)) | Vitamin A | 4 / 4 | THR C 9LEU C 13VAL C 16LEU C 20 | 0.39A | 23.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4 / 6 | SER C 57ILE D 119THR D 123ALA D 194 | 1.48A | 12.28 | NoneNoneNoneEDO D 201 (-3.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YVN_A_ACTA305_0 (GLUTATHIONES-TRANSFERASEOMEGA-1) | Acetic acid | 4 / 6 | LEU C 71GLN D 88LEU C 13LEU C 59 | 1.42A | 16.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XDK_B_9CRB600_1 (RETINOIC ACIDRECEPTOR, BETA) | Alitretinoin | 5 / 12 | ALA C 65LEU C 17LEU C 20LEU C 28LEU C 59 | 1.11A | 15.56 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1PBK_A_RAPA225_1 (FKBP25) | Sirolimus | 5 / 12 | GLY B 113VAL B 131ILE B 132ALA B 188ILE B 156 | 1.18A | 17.21 | NoneNoneNoneNoneEDO B 202 ( 4.6A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UVV_B_9CRB501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) | Alitretinoin | 5 / 12 | ALA D 152ALA D 150VAL D 186ILE D 132CYH D 114 | 1.34A | 18.03 | EDO D 201 ( 4.0A)EDO D 201 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4E0F_A_RBFA301_2 (RIBOFLAVIN SYNTHASESUBUNIT ALPHA) | Riboflavin | 3 / 3 | LYS D 127THR D 187ILE D 166 | 1.20A | 19.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4 / 6 | THR C 46ILE D 120ASP D 101THR C 45 | 1.43A | 14.64 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2RKG_B_AB1B501_2 (PROTEASE RETROPEPSIN) | Lopinavir | 5 / 12 | LEU B 103ALA B 150VAL B 130ILE B 119ILE B 106 | 0.94A | 17.69 | NoneEDO B 201 (-3.6A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9K_A_TYLA2200_1 (CREB-BINDING PROTEIN) | Acetaminophen | 4 / 6 | VAL D 130LEU D 128ILE D 120ASN D 105 | 1.15A | 28.26 | NoneNoneNoneEDO D 202 (-4.2A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1TDR_A_MTXA170_2 (TELLUROMETHIONYLDIHYDROFOLATEREDUCTASE) | Methotrexate | 3 / 3 | SER C 61ILE D 185THR D 137 | 1.35A | 17.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FBM_B_RTLB951_3 (PROTEIN (CARTILAGEOLIGOMERIC MATRIXPROTEIN)) | Vitamin A | 4 / 5 | THR A 9LEU A 13VAL A 16LEU A 20 | 0.63A | 23.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5E5K_B_017B201_1 (HIV-1 PROTEASE) | Darunavir | 5 / 12 | LEU D 103ALA D 150VAL D 130ILE D 119ILE D 106 | 0.89A | 19.05 | NoneEDO D 201 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3W68_A_VIVA301_0 (ALPHA-TOCOPHEROLTRANSFER PROTEIN) | Vitamin E | 6 / 12 | VAL A 53SER A 57LEU A 60SER A 61LEU A 17VAL A 22 | 1.37A | 16.41 | EDO B 201 ( 4.7A)NoneNoneNoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3S54_B_017B201_2 (PROTEASE) | Darunavir | 5 / 12 | LEU D 103ALA D 150VAL D 130ILE D 119ILE D 106 | 0.93A | 19.05 | NoneEDO D 201 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9K_A_TYLA2200_1 (CREB-BINDING PROTEIN) | Acetaminophen | 4 / 6 | VAL B 130LEU B 128ILE B 120ASN B 105 | 1.20A | 28.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XIW_B_LOCB504_1 (TUBULIN ALPHA-1BCHAINTUBULIN BETA CHAIN) | Colchicine | 3 / 3 | SER C 25ALA C 30VAL C 33 | 1.08A | 11.50 | NoneEDO C 101 (-3.5A)EDO C 101 ( 4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4 / 6 | ILE C 39ALA C 48THR C 46ALA D 194 | 1.48A | 12.28 | NoneNoneNoneEDO D 201 (-3.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1OPJ_A_STIA3_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) | Imatinib | 5 / 12 | ILE D 132VAL D 115LEU C 60ALA D 110ASP D 112 | 1.22A | 18.15 | NoneNoneNoneNoneEDO D 202 (-4.1A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4 / 6 | SER A 57ILE B 119THR B 123ALA B 152 | 1.43A | 12.28 | NoneNoneNoneEDO B 201 ( 4.0A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VC0_A_RITA602_1 (CYTOCHROME P450 3A4) | Ritonavir | 5 / 12 | LEU D 103ILE C 39PHE C 49ALA C 48ALA C 0 | 1.47A | 12.88 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QEU_A_ACTA141_0 (PUTATIVECARBOXYMUCONOLACTONEDECARBOXYLASE) | Acetic acid | 3 / 3 | VAL B 167ASP B 161GLU B 171 | 1.34A | 21.19 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1PBK_A_RAPA225_1 (FKBP25) | Sirolimus | 5 / 12 | GLY D 113VAL D 131ILE D 132ALA D 188ILE D 156 | 1.17A | 17.21 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2RKG_B_AB1B501_2 (PROTEASE RETROPEPSIN) | Lopinavir | 5 / 12 | LEU D 103ALA D 150VAL D 130ILE D 119ILE D 106 | 0.91A | 17.69 | NoneEDO D 201 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5T8H_B_478B401_1 (PROTEASE) | Amprenavir | 5 / 12 | LEU B 103ALA B 150VAL B 130ILE B 119ILE B 106 | 0.95A | 19.05 | NoneEDO B 201 (-3.6A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1DB1_A_VDXA428_2 (VITAMIN D NUCLEARRECEPTOR) | Calcitriol | 4 / 6 | ILE D 156TRP D 154TYR D 149VAL D 160 | 1.38A | 18.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FBM_B_RTLB951_3 (PROTEIN (CARTILAGEOLIGOMERIC MATRIXPROTEIN)) | Vitamin A | 4 / 5 | THR C 9LEU C 13VAL C 16LEU C 20 | 0.60A | 23.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HCX_A_ZMRA519_1 (NEURAMINIDASE) | Zanamivir | 3 / 3 | TRP D 154ILE D 120GLU C 50 | 1.14A | 17.29 | NoneNoneEDO D 201 ( 4.6A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6AZ3_1_PAR11803_1 (RRNA ALPHARIBOSOMAL PROTEINEL18) | Paromomycin | 3 / 3 | SER A 1LYS A 2SER A 4 | 1.19A | 17.62 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1OPJ_A_STIA3_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) | Imatinib | 5 / 12 | ILE B 132VAL B 115LEU A 60ALA B 110ASP B 112 | 1.20A | 18.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5E5K_B_017B201_1 (HIV-1 PROTEASE) | Darunavir | 5 / 12 | LEU B 103ALA B 150VAL B 130ILE B 119ILE B 106 | 0.92A | 19.05 | NoneEDO B 201 (-3.6A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WDM_A_ADNA901_1 (4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE) | Adenosine | 5 / 9 | GLY B 113LEU A 60ASN A 69ASN B 109ILE B 106 | 1.49A | 19.08 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XI3_A_29SA601_2 (ESTROGEN RECEPTOR) | Bazedoxifene | 3 / 3 | LEU D 91ILE C 68LEU C 60 | 0.72A | 18.29 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2DTJ_A_THRA401_0 (ASPARTOKINASE) | L-Threonine | 4 / 8 | GLY B 113ALA B 110ASN A 69ILE A 68 | 1.08A | 20.99 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4 / 6 | ILE A 39ALA A 48THR A 46ALA B 102 | 1.50A | 12.28 | NoneNoneNoneEDO B 201 ( 4.2A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_0 (TYROSINE-PROTEINKINASE ABL1) | Imatinib | 5 / 12 | ILE B 132VAL B 115LEU A 60ALA B 110ASP B 112 | 1.22A | 18.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QEU_A_ACTA141_0 (PUTATIVECARBOXYMUCONOLACTONEDECARBOXYLASE) | Acetic acid | 3 / 3 | VAL D 167ASP D 161GLU D 171 | 1.38A | 21.19 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LIN_A_TFPA153_1 (CALMODULIN) | Trifluoperazine | 4 / 8 | LEU C 40GLU C 47ALA C 48VAL C 6 | 1.46A | 20.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HCX_A_ZMRA519_1 (NEURAMINIDASE) | Zanamivir | 3 / 3 | TRP B 154ILE B 120GLU A 50 | 1.12A | 17.29 | NoneNoneEDO B 201 ( 4.5A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4 / 6 | THR A 46ILE B 120ASP B 101THR A 45 | 1.48A | 14.64 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_A_P06A801_2 (SERINE/THREONINE-PROTEIN KINASE B-RAF) | Dabrafenib | 3 / 3 | PHE B 92ILE B 107ASP B 99 | 0.85A | 18.38 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_A_P06A801_2 (SERINE/THREONINE-PROTEIN KINASE B-RAF) | Dabrafenib | 3 / 3 | PHE D 92ILE D 107ASP D 99 | 0.88A | 18.38 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UVV_B_9CRB501_1 (RETINOIC ACIDRECEPTOR RXR-ALPHA) | Alitretinoin | 5 / 12 | ALA B 152ALA B 150VAL B 186ILE B 132CYH B 114 | 1.30A | 18.03 | EDO B 201 ( 4.0A)EDO B 201 (-3.6A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MRQ_A_STRA501_1 (ALDO-KETO REDUCTASEFAMILY 1 MEMBER C1) | Progesterone | 5 / 11 | LEU C 59VAL C 66ILE C 68LEU D 103LEU D 95 | 1.49A | 15.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4 / 6 | ILE C 39ALA C 48THR C 46ALA D 102 | 1.49A | 12.28 | NoneNoneNoneEDO D 201 ( 4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FBM_B_RTLB951_2 (PROTEIN (CARTILAGEOLIGOMERIC MATRIXPROTEIN)) | Vitamin A | 4 / 4 | THR A 9LEU A 13VAL A 16LEU A 20 | 0.41A | 23.75 | None |