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| PDB ID: 6g13 Macromolecule: NUCLEOPROTEIN Source Organism: MERS-CoV Gene names: - UniProt ID: A0A0D3MU51 |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO PDBID '6g13'
1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.| DrReposER ID / Desc. | Drug | Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OZV_A_ECNA411_1 (FLAVOHEMOGLOBIN) | Econazole | 4 / 8 | ILE D 306ALA B 313LEU D 361ILE D 365 | 1.17A | 15.46 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B58_A_ACTA603_0 (FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT) | Acetic acid | 3 / 3 | TYR B 337ASN D 355LEU D 358 | 1.17A | 12.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE) | Pantothenic acid | 4 / 7 | ARG A 279PHE A 288PHE C 322ILE A 306 | 1.42A | 14.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4JBT_A_ASDA501_1 (CYTOCHROME P450MONOOXYGENASE) | 4-Androstenedione | 5 / 12 | PHE A 322ALA C 307ALA C 310ALA A 313THR A 312 | 1.36A | 14.91 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B58_A_ACTA603_0 (FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT) | Acetic acid | 3 / 3 | TYR D 337ASN B 355LEU B 358 | 1.20A | 12.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FOF_F_MFXF0_1 (DNA TOPOISOMERASE 4SUBUNIT A) | Moxifloxacin | 2 / 3 | GLY C 318SER C 314 | 0.33A | 12.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE) | Adenosine | 4 / 8 | ARG D 261PHE D 270GLY D 297THR D 298 | 1.41A | 12.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B58_A_ACTA603_0 (FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT) | Acetic acid | 3 / 3 | TYR C 337ASN A 355LEU A 358 | 1.17A | 12.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4N49_A_SAMA601_1 (CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1) | S-Adenosylmethionine | 4 / 4 | ASN B 364GLY B 289ASP A 290ASP B 300 | 1.24A | 13.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE) | Adenosine | 4 / 8 | ARG C 261PHE C 270GLY C 297THR C 298 | 1.36A | 12.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EXI_A_ADNA503_1 (ADENOSYLHOMOCYSTEINASE) | Adenosine | 3 / 3 | LEU A 360GLN A 305LYS D 263 | 1.34A | 13.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5SYJ_A_NIZA809_1 (CATALASE-PEROXIDASE) | Isoniazid | 4 / 8 | ARG A 302GLY A 297GLN A 292LEU A 293 | 0.96A | 10.99 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OZV_A_ECNA411_1 (FLAVOHEMOGLOBIN) | Econazole | 4 / 8 | ILE B 306ALA D 313LEU B 361ILE B 365 | 1.16A | 15.46 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NDV_1_PAR13413_1 (25S RIBOSOMAL RNA5S RIBOSOMAL RNA) | Paromomycin | 3 / 3 | LYS A 356GLU A 359LYS D 263 | 1.12A | 11.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5SXQ_A_NIZA808_1 (CATALASE-PEROXIDASE) | Isoniazid | 4 / 8 | ARG A 302GLY A 297GLN A 292LEU A 293 | 0.97A | 10.99 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_A_ANWA601_0 (RHODOPSIN KINASE) | Amlexanox | 4 / 7 | LEU C 339ILE A 365LEU A 360ALA A 310 | 1.36A | 12.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE) | Adenosine | 4 / 8 | ARG A 261PHE A 270GLY A 297THR A 298 | 1.34A | 12.10 | NoneTMO A 402 (-3.5A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A83_A_DXCA1160_0 (MAJOR POLLENALLERGEN BET V 1-A) | Deoxycholic Acid | 5 / 12 | PRO A 301LEU A 296ALA D 313SER D 314MET D 317 | 1.20A | 18.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OZV_A_ECNA411_1 (FLAVOHEMOGLOBIN) | Econazole | 4 / 8 | ILE C 306ALA A 313LEU C 361ILE C 365 | 1.17A | 15.46 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE) | Pantothenic acid | 4 / 7 | ARG D 279PHE D 288PHE B 322ILE D 306 | 1.45A | 14.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3S53_A_017A201_1 (PROTEASE) | Darunavir | 5 / 9 | ALA B 367ASP B 366ILE B 365GLY B 286ILE B 306 | 1.36A | 18.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4JBT_A_ASDA501_1 (CYTOCHROME P450MONOOXYGENASE) | 4-Androstenedione | 5 / 12 | PHE C 322ALA A 307ALA A 310ALA C 313THR C 312 | 1.36A | 14.91 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LII_A_ADNA699_1 (ADENOSINE KINASE) | Adenosine | 5 / 12 | ILE A 306LEU C 339LEU A 309ASN A 294ASP A 290 | 1.50A | 16.02 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B58_A_ACTA603_0 (FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT) | Acetic acid | 3 / 3 | TYR A 337ASN C 355LEU C 358 | 1.16A | 12.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE) | Raltitrexed | 4 / 7 | PHE D 276ASP D 290LEU D 293GLY D 289 | 1.25A | 19.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4JBT_A_ASDA501_1 (CYTOCHROME P450MONOOXYGENASE) | 4-Androstenedione | 5 / 12 | PHE D 322ALA B 307ALA B 310ALA D 313THR D 312 | 1.35A | 14.91 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE) | Raltitrexed | 4 / 7 | PHE B 276ASP B 290LEU B 293GLY B 289 | 1.20A | 19.42 | None CL B 402 (-4.7A)NoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OZV_A_ECNA411_1 (FLAVOHEMOGLOBIN) | Econazole | 4 / 8 | ILE A 306ALA C 313LEU A 361ILE A 365 | 1.28A | 15.46 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WBV_A_SAMA402_1 (HISTONE-LYSINEN-METHYLTRANSFERASEKMT5B) | S-Adenosylmethionine | 3 / 3 | HIS D 262GLU B 308ASN B 351 | 1.48A | 18.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3E23_A_SAMA221_1 (UNCHARACTERIZEDPROTEIN RPA2492) | S-Adenosylmethionine | 3 / 3 | TYR C 354ASP A 330HIS A 326 | 1.11A | 18.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3S53_A_017A201_1 (PROTEASE) | Darunavir | 5 / 9 | ALA A 367ASP A 366ILE A 365GLY A 286ILE A 306 | 1.37A | 18.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE) | Raltitrexed | 4 / 7 | PHE C 276ASP C 290LEU C 293GLY C 289 | 1.23A | 19.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OBV_A_SAMA501_0 (S-ADENOSYLMETHIONINESYNTHETASE ISOFORMTYPE-1) | S-Adenosylmethionine | 4 / 8 | HIS A 262SER C 314SER A 266PHE A 276 | 1.32A | 15.64 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A83_A_DXCA1160_0 (MAJOR POLLENALLERGEN BET V 1-A) | Deoxycholic Acid | 5 / 12 | PRO A 301LEU A 296GLN A 363ALA D 313SER D 314 | 1.33A | 18.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WBV_A_SAMA402_1 (HISTONE-LYSINEN-METHYLTRANSFERASEKMT5B) | S-Adenosylmethionine | 3 / 3 | HIS A 262GLU C 308ASN C 351 | 1.47A | 18.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XK8_A_PQNA844_1 (PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1) | Phylloquinone | 4 / 7 | PHE A 322ARG A 340ALA C 344LEU A 339 | 1.30A | 9.92 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3S53_A_017A201_1 (PROTEASE) | Darunavir | 5 / 9 | ALA D 367ASP D 366ILE D 365GLY D 286ILE D 306 | 1.31A | 18.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE) | Pantothenic acid | 4 / 7 | ARG C 279PHE C 288PHE A 322ILE C 306 | 1.45A | 14.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0O_A_SAMA501_1 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 3 / 3 | ALA A 344GLN C 327THR C 325 | 1.17A | 16.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WBV_A_SAMA402_1 (HISTONE-LYSINEN-METHYLTRANSFERASEKMT5B) | S-Adenosylmethionine | 3 / 3 | HIS C 262GLU A 308ASN A 351 | 1.48A | 18.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PD9_A_ADNA501_2 (NUPC FAMILY PROTEIN) | Adenosine | 3 / 3 | THR D 298ASN A 287PHE A 288 | 0.92A | 16.92 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4JBT_A_ASDA501_1 (CYTOCHROME P450MONOOXYGENASE) | 4-Androstenedione | 5 / 12 | PHE B 322ALA D 307ALA D 310ALA B 313THR B 312 | 1.38A | 14.91 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XWF_A_ADNA433_2 (ADENOSYLHOMOCYSTEINASE) | Adenosine | 3 / 3 | THR D 265GLU A 359HIS D 262 | 1.35A | 14.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE) | Raltitrexed | 4 / 7 | PHE A 276ASP A 290LEU A 293GLY A 289 | 1.23A | 19.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XK8_A_PQNA844_1 (PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1) | Phylloquinone | 4 / 7 | PHE B 322ARG B 340ALA D 344LEU B 339 | 1.34A | 9.92 | None |