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| PDB ID: 1zva Macromolecule: E2 GLYCOPROTEIN Source Organism: SARSr Gene names: - UniProt ID: P59594 |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO PDBID '1zva'
1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.| DrReposER ID / Desc. | Drug | Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PO0_A_NPSA603_1 (SERUM ALBUMIN) | Naproxen | 5 / 10 | VAL A 20LEU A 62ASN A 17LEU A 16VAL A 65 | 1.39A | 8.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R9V_B_DXCB323_0 (INVASIN IPAD) | Deoxycholic Acid | 5 / 7 | ILE A 30ILE A 48VAL A 33LEU A 34SER A 32 | 1.65A | 17.11 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3AOD_A_MIYA2001_1 (ACRIFLAVINERESISTANCE PROTEIN B) | Minocycline | 4 / 8 | PHE A 27ASN A 49ILE A 48ALA A 29 | 0.94A | 6.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2E7F_B_C2FB4000_0 (5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE) | Levomefolic acid | 5 / 12 | ILE A 55LEU A 23GLY A 28SER A 32ILE A 30 | 1.41A | 16.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EF6_A_BEZA401_0 (AMINOGLYCOSIDEPHOSPHOTRANSFERASE) | Benzoic Acid | 5 / 9 | LEU A 34SER A 32ILE A 48VAL A 52ILE A 30 | 1.57A | 11.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KO0_B_TFPB202_2 (PROTEIN S100-A4) | Trifluoperazine | 4 / 6 | LEU A 23SER A 25PHE A 27ILE A 55 | 1.02A | 22.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MZ9_D_VDYD1001_2 (CARTILAGE OLIGOMERICMATRIX PROTEIN) | Calcidiol | 3 / 3 | LEU A 62VAL A 65LEU A 69 | 0.68A | 23.38 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5DSG_B_0HKB1201_2 (MUSCARINICACETYLCHOLINERECEPTORM4,ENDOLYSIN,ENDOLYSIN,MUSCARINICACETYLCHOLINERECEPTOR M4) | Tiotropium | 3 / 3 | ASP A 60ASN A 54PHE A 27 | 0.85A | 13.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XT8_A_TMQA302_1 (RV2671) | Trimetrexate | 5 / 12 | ASN A 54SER A 25GLY A 28ALA A 29GLU A 58 | 1.69A | 14.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ILU_B_HFZB800_1 (GLUTAMATE RECEPTOR 2) | Hydroflumethiazide | 5 / 10 | SER A 46LEU A 34SER A 32ILE A 37GLY A 43 | 1.36A | 13.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OKX_A_198A1002_2 (ANDROGEN RECEPTOR) | Bicalutamide | 4 / 6 | LEU A 69ASN A 70LEU A 5ILE A 74 | 1.37A | 15.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OA1_B_ADNB2005_1 (TRYPTOPHANHALOGENASE) | Adenosine | 5 / 7 | GLY A 39GLY A 40VAL A 33SER A 38LEU A 34 | 1.69A | 11.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2H4J_A_NCAA1002_0 (NAD-DEPENDENTDEACETYLASE) | Nicotinamide | 4 / 5 | ALA A 29ILE A 48ASN A 26ILE A 55 | 1.65A | 14.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KO0_B_TFPB202_1 (PROTEIN S100-A4) | Trifluoperazine | 3 / 3 | GLU A 58LEU A 62ASP A 60 | 0.79A | 22.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U7S_A_017A201_1 (POL POLYPROTEIN) | Darunavir | 5 / 9 | LEU A 34GLY A 28ALA A 29ILE A 55VAL A 33 | 1.53A | 22.12 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3DMH_A_SAMA384_1 (PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE) | S-Adenosylmethionine | 3 / 3 | SER A 31GLU A 58ASP A 60 | 1.23A | 11.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L49_A_CAMA502_0 (CAMPHOR5-MONOOXYGENASE) | Camphor | 4 / 5 | PHE A 27LEU A 34VAL A 33VAL A 52 | 1.65A | 11.48 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1E06_A_IPBA600_0 (ODORANT-BINDINGPROTEIN) | Thymol | 4 / 6 | VAL A 53ASN A 54ILE A 30ASN A 26 | 1.00A | 17.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2E7F_A_C2FA3000_0 (5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE) | Levomefolic acid | 5 / 12 | ILE A 55LEU A 23GLY A 28SER A 32ILE A 30 | 1.45A | 16.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DT8_A_ADNA401_1 (APH(2'')-ID) | Adenosine | 5 / 11 | SER A 31GLY A 28ALA A 29ILE A 30ILE A 55 | 1.60A | 14.04 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZUL_A_SAMA376_1 (PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE) | S-Adenosylmethionine | 3 / 3 | SER A 31GLU A 58ASP A 60 | 1.25A | 11.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M11_C_MXMC606_1 (PROSTAGLANDIN G/HSYNTHASE 2) | Meloxicam | 5 / 12 | VAL A 20VAL A 65LEU A 69LEU A 62ALA A 13 | 1.35A | 9.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WDM_C_ADNC301_1 (4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE) | Adenosine | 5 / 9 | ALA A 29ASP A 36LEU A 34ASN A 35ILE A 45 | 1.34A | 18.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK6_B_HCZB262_1 (GLUTAMATE RECEPTOR 2) | Hydrochlorothiazide | 5 / 10 | ILE A 37GLY A 43SER A 46LEU A 34SER A 32 | 1.34A | 13.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2DRD_A_MIYA2001_1 (ACRB) | Minocycline | 5 / 9 | PHE A 27ASN A 49ILE A 48ALA A 29VAL A 33 | 1.42A | 6.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1D4S_A_TPVA201_2 (PROTEIN (HIV-1PROTEASE)) | Tipranavir | 4 / 8 | LEU A 34ALA A 29GLY A 47VAL A 33 | 1.09A | 21.21 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1DZM_A_BZMA600_0 (ODORANT-BINDINGPROTEIN) | Benzyl Benzoate | 4 / 8 | VAL A 53ASN A 54ASN A 26GLY A 28 | 1.25A | 17.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OGY_A_C2FA3000_0 (5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE) | Levomefolic acid | 5 / 12 | ILE A 55LEU A 23GLY A 28SER A 32ILE A 30 | 1.44A | 15.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A81_A_DXCA1161_0 (MAJOR POLLENALLERGEN BET V 1-A) | Deoxycholic Acid | 5 / 12 | GLY A 43ASP A 44ILE A 48VAL A 52LEU A 34 | 1.64A | 19.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KOX_A_RFPA502_1 (PENTACHLOROPHENOL4-MONOOXYGENASE) | Rifampicin | 5 / 12 | GLY A 39GLY A 28ILE A 30GLY A 43GLY A 42 | 1.37A | 9.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6G9I_B_CXXB707_1 (ENVELOPEGLYCOPROTEIN,ENVELOPE GLYCOPROTEIN) | Clomipramine | 5 / 7 | ILE A 55LEU A 23VAL A 65LEU A 62LEU A 19 | 1.60A | 12.1118.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OZV_A_ECNA411_1 (FLAVOHEMOGLOBIN) | Econazole | 4 / 8 | ILE A 48ILE A 45LEU A 34ILE A 30 | 1.44A | 12.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M11_B_MXMB606_1 (PROSTAGLANDIN G/HSYNTHASE 2) | Meloxicam | 5 / 12 | VAL A 20VAL A 65LEU A 69LEU A 62ALA A 13 | 1.37A | 9.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1N3Z_A_ADNA126_1 (RIBONUCLEASE,SEMINAL) | Adenosine | 5 / 9 | ALA A 66LYS A 67GLN A 22ALA A 15VAL A 65 | 1.79A | 19.17 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RMT_B_ADNB1502_1 (CLASS B ACIDPHOSPHATASE) | Adenosine | 4 / 7 | GLU A 58LEU A 62THR A 18LYS A 21 | 1.72A | 16.19 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PSS_A_FOLA201_0 (DIHYDROFOLATEREDUCTASE) | Folic Acid | 5 / 12 | ALA A 66LEU A 16ALA A 15LEU A 23ILE A 59 | 1.27A | 21.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2YCJ_A_C2FA3000_0 (5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE) | Levomefolic acid | 5 / 12 | ILE A 55LEU A 23GLY A 28SER A 32ILE A 30 | 1.50A | 15.93 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6AG0_A_ACRA606_0 (ALPHA-AMYLASE) | Acarbose | 4 / 7 | GLY A 39GLY A 40GLY A 42GLY A 43 | 1.00A | 13.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIJ_B_NOVB444_1 (DNA GYRASE SUBUNIT B) | Novobiocin | 5 / 12 | ASN A 54ILE A 30ASP A 36ILE A 48ALA A 50 | 1.77A | 13.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KPD_B_SAMB1000_1 (UNCHARACTERIZEDPROTEIN MJ0100) | S-Adenosylmethionine | 3 / 3 | ASN A 70ASN A 68GLU A 64 | 1.42A | 20.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AN2_A_EUIA1382_2 (DUAL SPECIFICITYMITOGEN-ACTIVATEDPROTEIN KINASEKINASE 1) | Cobimetinib | 4 / 4 | ASN A 17SER A 72LEU A 69THR A 18 | 1.75A | 14.49 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3N8W_A_FLPA701_1 (PROSTAGLANDIN G/HSYNTHASE 1) | Flurbiprofen | 5 / 12 | VAL A 20VAL A 65LEU A 69LEU A 62ALA A 13 | 1.39A | 13.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FOF_F_MFXF0_1 (DNA TOPOISOMERASE 4SUBUNIT A) | Moxifloxacin | 2 / 3 | GLY A 28SER A 24 | 0.19A | 9.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2) | Hydroflumethiazide | 5 / 11 | ILE A 37GLY A 43SER A 46LEU A 34SER A 32 | 1.32A | 13.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3A2Q_A_ACAA601_1 (6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE) | Aminocaproic Acid | 5 / 7 | GLY A 47ASN A 49ALA A 29VAL A 33ILE A 45 | 1.56A | 10.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WDM_B_ADNB301_1 (4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE) | Adenosine | 5 / 10 | ALA A 29ASP A 36LEU A 34ASN A 35ILE A 45 | 1.52A | 18.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3I9J_B_NCAB302_0 (ADP-RIBOSYL CYCLASE) | Nicotinamide | 4 / 6 | LEU A 23GLU A 58ASN A 54SER A 24 | 1.78A | 17.78 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2C2B_E_SAME500_0 (THREONINE SYNTHASE1, CHLOROPLASTIC) | S-Adenosylmethionine | 5 / 11 | SER A 32GLY A 28SER A 51PHE A 27ASP A 36 | 1.74A | 10.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OR0_B_NPSB602_1 (SERUM ALBUMIN) | Naproxen | 5 / 9 | ALA A 15ALA A 13LEU A 16LEU A 19VAL A 20 | 1.57A | 8.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_B_B49B1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) | Sunitinib | 5 / 10 | VAL A 33ALA A 29ILE A 55PHE A 27GLY A 47 | 1.46A | 12.39 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WDM_A_ADNA901_1 (4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE) | Adenosine | 5 / 9 | ALA A 29ASP A 36LEU A 34ASN A 35ILE A 45 | 1.33A | 18.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LIN_A_TFPA156_1 (CALMODULIN) | Trifluoperazine | 4 / 8 | LEU A 34ILE A 30VAL A 52ILE A 48 | 1.15A | 19.26 | None |