POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	2pxj	JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A (Homo sapiens)	5 / 12	GLY A  80 ILE A 245 THR A  83 VAL A  75 LEU A 222	None	1.38A	20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	4gbr	BETA-2 ADRENERGIC RECEPTOR (Homo sapiens)	5 / 12	GLY A 252 ILE A 250 PHE A 254 ASN A 294 LEU A  75	None	1.47A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	4lxl	LYSINE-SPECIFIC DEMETHYLASE 4B (Homo sapiens)	5 / 12	GLY A  81 ILE A 246 THR A  84 VAL A  76 LEU A 223	None	1.37A	21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	4xdo	LYSINE-SPECIFIC DEMETHYLASE 4C (Homo sapiens)	5 / 12	GLY A  82 ILE A 247 THR A  85 VAL A  77 LEU A 224	None	1.32A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	4y89	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 7 (Homo sapiens)	5 / 12	GLY A  31 ILE A  93 VAL A  22 ASN A  99 LEU A  97	None	1.16A	18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	5a2f	CD166 ANTIGEN (Homo sapiens)	5 / 12	TYR A  29 THR A 126 VAL A  31 LEU A 115 TRP A  56	None	1.04A	17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	5h1c	DNA REPAIR PROTEIN RAD51 HOMOLOG 1 (Homo sapiens)	5 / 12	GLY A 335 PHE A 327 THR A 139 VAL A 174 LEU A 112	None	1.37A	19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	5u0u	DH270.1 SINGLE-CHAIN VARIABLE FRAGMENT (Homo sapiens)	5 / 12	GLY G  99 ILE G  34 TRP G 117 TYR G 116 VAL G   2	None	1.31A	19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZ0_A_ZLDA301_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR)	5u8q	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR FV 24-60 HEAVY CHAIN (Homo sapiens; Mus musculus)	5 / 12	TRP A 244 GLY A  27 ILE A  25 TYR H  54 LEU A  19	None	1.36A	undetectable