POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	1ad9	IGG CTM01 FAB (HEAVY CHAIN) (Homo sapiens)	4 / 6	ASN H  76 ALA H  24 PRO H  52 TYR H  27	None	1.05A	17.04 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	1b41	ACETYLCHOLINESTERASE (Homo sapiens)	4 / 6	ASN A 170 PRO A  49 VAL A 171 ASP A 304	None	1.16A	10.28 10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	2hrb	CARBONYL REDUCTASE [NADPH] 3 (Homo sapiens)	4 / 6	ASN A 137 ALA A 225 PRO A 251 VAL A 136	None	1.18A	14.13 13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	2l0b	E3 UBIQUITIN-PROTEIN LIGASE PRAJA-1 (Homo sapiens)	4 / 6	ALA A  56 VAL A  70 ASP A  54 TYR A  50	None	1.16A	20.00 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	2pa5	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 (Homo sapiens)	4 / 6	ASN A 370 ALA A 371 PRO A 509 ASP A 364	None	1.22A	13.55 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	3bhi	CARBONYL REDUCTASE [NADPH] 1 (Homo sapiens)	4 / 6	ASN A 136 ALA A 224 PRO A 250 VAL A 135	None	1.05A	13.77 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	3eo9	EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	4 / 6	ASN H  77 ALA H  24 PRO H  53 TYR H  27	None	1.05A	20.43 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	3ntc	FAB HEAVY CHAIN (Homo sapiens; Mus musculus)	4 / 6	ASN H  76 ALA H  24 PRO H  52 TYR H  27	EDO  H 222 (-2.7A) None None None	1.14A	17.41 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	5b4x	LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8, APOLIPOPROTEIN E RECEPTOR, ISOFORM CRA_E (Homo sapiens)	4 / 6	ASN B 262 VAL B 261 ASP B 246 TYR B 266	CA  B5004 (-3.1A) None CA  B5004 (-2.5A) None	1.23A	8.33 7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	5i8e	VRC34.01 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	ASN A  76 ALA A  24 PRO A  52 TYR A  27	None	0.97A	20.09 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	5okl	AFAMIN (Homo sapiens)	4 / 6	ASN A 554 ALA A 553 PRO A 574 VAL A 555	None	1.16A	21.43 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1xfd	DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 (Homo sapiens)	5 / 9	GLY A 664 VAL A 676 GLU A 675 GLY A 666 PRO A 632	None	1.34A	7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zlr	COAGULATION FACTOR XI (Homo sapiens)	5 / 9	VAL A 210 GLY A 184 TYR A 228 VAL A 163 PRO A 225	None	1.36A	16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2bex	RIBONUCLEASE INHIBITOR (Homo sapiens)	5 / 9	VAL A 335 GLY A 299 GLU A 305 ASP A 297 GLY A 296	None	1.27A	11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2bwj	ADENYLATE KINASE 5 (Homo sapiens)	5 / 9	GLY A 109 TYR A  98 GLU A 106 GLY A 113 PRO A 115	None	1.35A	18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2pi2	REPLICATION PROTEIN A 14 KDA SUBUNIT (Homo sapiens)	5 / 9	VAL E  25 GLY E  29 VAL E  67 GLU E  68 ASP E  45	None	1.19A	19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3bvh	FIBRINOGEN BETA CHAIN (Homo sapiens)	5 / 9	GLY B 414 TYR B 422 VAL B 435 ASP B 398 GLY B 399	None	1.36A	16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3h32	FIBRINOGEN BETA CHAIN (Homo sapiens)	5 / 9	GLY B 414 TYR B 404 ASP B 433 GLY B 434 PRO B 412	None	1.32A	11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3pow	CALRETICULIN (Homo sapiens)	5 / 9	VAL A 184 TYR A 172 VAL A 110 ASP A 135 GLY A 107	None	1.24A	14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4wlh	KYNURENINE--OXOGLUTA RATE TRANSAMINASE 1 (Homo sapiens)	5 / 9	VAL A 179 GLY A 243 VAL A 215 GLU A 214 GLY A 257	None None LLP  A 247 ( 3.7A) None None	1.33A	11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	4wp0	KYNURENINE--OXOGLUTA RATE TRANSAMINASE 1 (Homo sapiens)	5 / 9	VAL A 179 GLY A 243 VAL A 215 GLU A 214 GLY A 257	None None LLP  A 247 ( 4.7A) None None	1.35A	11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5e6s	INTEGRIN ALPHA-L (Homo sapiens)	5 / 9	GLY A 328 VAL A 340 ASP A  87 GLY A 102 PRO A 120	None	1.34A	6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5eod	COAGULATION FACTOR XI (Homo sapiens)	5 / 9	VAL A 572 GLY A 544 TYR A 590 VAL A 522 PRO A 587	None	1.39A	8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5f8z	PLASMA KALLIKREIN LIGHT CHAIN (Homo sapiens)	5 / 9	VAL A 210 GLY A 184 TYR A 228 VAL A 163 PRO A 225	None	1.35A	16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5f9o	CH235.9 HEAVY CHAIN (Homo sapiens)	5 / 9	VAL H  68 GLY H   8 TYR H  94 MET H  81 GLY H  10	None	1.20A	17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	6c9d	SERINE/THREONINE-PRO TEIN KINASE MARK1,SERINE/THREONI NE-PROTEIN KINASE MARK1 (Homo sapiens)	5 / 9	GLY A 141 TYR A 147 GLU A 143 ASP A 191 GLY A 192	None	1.19A	22.35