POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	2d7t	ANTI POLYHYDROXYBUTYRATE ANTIBODY FV, HEAVY CHAIN ANTI POLYHYDROXYBUTYRATE ANTIBODY FV, LIGHT CHAIN (Homo sapiens)	5 / 12	HIS H 35 VAL H 37 TRP H 50 TRP H 106 LEU L 89	None	0.67A	37.61 22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	2qyk	CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE HSPDE4A10 (Homo sapiens)	5 / 12	HIS A 445 VAL A 448 HIS A 416 PRO A 417 LEU A 431	None	1.31A	22.59 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3g4g	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	5 / 12	HIS A 399 VAL A 402 HIS A 370 PRO A 371 LEU A 385	None	1.30A	18.98 20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3mnz	ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN (Homo sapiens; Mus musculus)	5 / 12	HIS B 35 VAL B 37 TRP B 50 TRP B 103 LEU A 89	None	0.65A	56.31 29.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3mnz	ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN (Homo sapiens; Mus musculus)	5 / 12	HIS B 35 VAL B 37 TRP B 103 TYR A 32 LEU A 89	None	0.85A	56.31 29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3o57	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	HIS A 307 VAL A 310 HIS A 278 PRO A 279 LEU A 293	None	1.31A	18.91 20.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3s35	6.64 FAB HEAVY CHAIN (Homo sapiens; Mus musculus)	5 / 12	HIS H 35 VAL H 37 TRP H 50 HIS H 99 TRP H 107	None	1.14A	88.94 26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	4mdk	UBIQUITIN-CONJUGATIN G ENZYME E2 R1 (Homo sapiens)	5 / 12	PHE A 58 VAL A 30 TYR A 53 HIS A 83 LEU A 124	U94 A 201 (-4.2A) None U94 A 201 (-4.0A) None None	1.46A	21.24 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	4wzi	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	HIS A 479 VAL A 482 HIS A 450 PRO A 451 LEU A 465	None	1.35A	16.69 16.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	4xi5	FAB-94 HEAVY CHAIN (Homo sapiens)	5 / 12	HIS D 35 VAL D 37 TRP D 111 HIS D 103 TYR D 106	None	1.36A	49.18 27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	5ohj	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B (Homo sapiens)	5 / 12	HIS A 479 VAL A 482 HIS A 450 PRO A 451 LEU A 465	None	1.25A	17.99 15.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	5u0u	DH270.1 SINGLE-CHAIN VARIABLE FRAGMENT (Homo sapiens)	5 / 12	HIS G 35 VAL G 37 TRP G 50 TRP G 117 TYR G 111	None	1.10A	38.49 25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	5wb9	N60P23 FAB HEAVY CHAIN (Homo sapiens)	5 / 12	PHE H 33 HIS H 35 VAL H 37 TRP H 50 TRP H 110	None	0.61A	23.19 15.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	8fab	IGG1-LAMBDA HIL FAB (HEAVY CHAIN) IGG1-LAMBDA HIL FAB (LIGHT CHAIN) (Homo sapiens)	5 / 12	PHE B 106 HIS B 35 TRP B 47 PRO B 100 TYR A 33	None	1.48A	53.12 28.63