POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	6 / 12	ASP A 174 TYR A 219 THR A 250 VAL A 254 ASN A 280 ASP A 285	None	0.81A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	7 / 12	TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 ASN A 313	None	0.46A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5uhk	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	9 / 12	LYS A  98 ASP A 174 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 ASN A 313	GOL  A 502 (-4.0A) GOL  A 501 (-3.1A) GOL  A 501 (-3.3A) GOL  A 501 (-4.4A) None GOL  A 501 (-3.6A) GOL  A 501 (-3.4A) GOL  A 502 (-2.9A) GOL  A 502 (-3.4A)	0.73A	24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5uhp	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	8 / 12	ASP A 174 TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 ASN A 313	GOL  A 501 (-2.5A) GOL  A 501 (-3.7A) GOL  A 501 (-4.2A) GOL  A 501 (-4.2A) GOL  A 501 (-3.8A) GOL  A 501 (-3.4A) None None	0.54A	29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	6 / 12	ASP A 174 TYR A 219 VAL A 254 ASN A 280 ASP A 285 ASN A 313	None	0.79A	25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_A_X0TA1625_1 (O-GLCNACASE NAGJ)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	7 / 12	TYR A 219 THR A 250 VAL A 254 TRP A 278 ASN A 280 ASP A 285 ASN A 313	None	0.40A	25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_B_X0TB1625_1 (O-GLCNACASE NAGJ)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	6 / 12	ASP A 174 TYR A 219 THR A 250 ASN A 280 ASP A 285 TYR A 286	None	0.74A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_B_X0TB1625_1 (O-GLCNACASE NAGJ)	5m7r	PROTEIN O-GLCNACASE (Homo sapiens)	7 / 12	TYR A 219 THR A 250 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	None	0.50A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_B_X0TB1625_1 (O-GLCNACASE NAGJ)	5uhk	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	9 / 12	LYS A  98 ASP A 174 TYR A 219 THR A 250 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	GOL  A 502 (-4.0A) GOL  A 501 (-3.1A) GOL  A 501 (-3.3A) GOL  A 501 (-4.4A) GOL  A 501 (-3.6A) GOL  A 501 (-3.4A) GOL  A 502 (-2.9A) None GOL  A 502 (-3.4A)	0.64A	24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_B_X0TB1625_1 (O-GLCNACASE NAGJ)	5uhp	O-GLCNACASE TIM-BARREL DOMAIN (Homo sapiens)	8 / 12	ASP A 174 TYR A 219 THR A 250 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	GOL  A 501 (-2.5A) GOL  A 501 (-3.7A) GOL  A 501 (-4.2A) GOL  A 501 (-3.8A) GOL  A 501 (-3.4A) None None None	0.54A	29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0Y_B_X0TB1625_1 (O-GLCNACASE NAGJ)	5vvo	PROTEIN O-GLCNACASE (Homo sapiens)	8 / 12	ASP A 174 TYR A 219 THR A 250 TRP A 278 ASN A 280 ASP A 285 TYR A 286 ASN A 313	None	0.74A	25.73