POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.28A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.26A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.23A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.45A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.24A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.40A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.30A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		1dv8 ASIALOGLYCOPROTEIN
RECEPTOR 1
(Homo
sapiens)		3 / 3ASP A 253
GLU A 252
GLY A 251
 CA  A1001 (-3.4A)
CA  A1002 ( 2.9A)
None
0.71A14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		1fzd FIBRINOGEN-420
(Homo
sapiens)		3 / 3ASP A 661
GLU A 685
GLY A 686
None
0.60A18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		1lv2 HEPATOCYTE NUCLEAR
FACTOR 4-GAMMA
(Homo
sapiens)		3 / 3ASP A 279
GLU A 286
GLY A 282
None
0.67A18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		2k6m SUPERVILLIN
(Homo
sapiens)		3 / 3ASP S  34
GLU S  31
GLY S  32
None
0.70A8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		2oqp INTERLEUKIN-21
(Homo
sapiens)		3 / 3ASP A  27
GLU A  65
GLY A  62
None
0.70A13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE
(Homo
sapiens)		3 / 3ASP A 769
GLU A 722
GLY A 723
None
0.66A19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		3kq4 CUBILIN
(Homo
sapiens)		3 / 3ASP B1221
GLU B1263
GLY B1264
 CA  B2016 (-2.2A)
None
CA  B2016 (-4.3A)
0.62A19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens)		3 / 3ASP X 327
GLU X 226
GLY X 224
None
ZN  X 400 ( 2.1A)
None
0.70A20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		3tdu DCN1-LIKE PROTEIN 1
(Homo
sapiens)		3 / 3ASP A 241
GLU A 233
GLY A 234
None
0.55A18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		4cpg SMALL GLUTAMINE-RICH
TETRATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN ALPHA
(Homo
sapiens)		3 / 3ASP A  63
GLU A  54
GLY A  58
None
0.71A11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE
(Homo
sapiens)		3 / 3ASP B1415
GLU B1411
GLY B1410
None
0.67A13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		4nsd CALCIUM UPTAKE
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens)		3 / 3ASP A 423
GLU A 427
GLY A 426
 CA  A 502 (-2.8A)
None
None
0.71A21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		5e5b FACT COMPLEX SUBUNIT
SPT16
(Homo
sapiens)		3 / 3ASP A  63
GLU A 145
GLY A 144
None
0.58A20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		5hvf CARBOXYPEPTIDASE B2
(Homo
sapiens)		3 / 3ASP A  38
GLU A 245
GLY A 246
None
0.52A21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		5mms CYSTATHIONINE
BETA-SYNTHASE
(Homo
sapiens)		3 / 3ASP A 281
GLU A 283
GLY A 284
None
0.70A21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens)		4 / 5GLU A 123
GLY A 122
TYR A 125
GLU A 133
None
1.44A20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		2boa CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A1237
GLY A1235
TYR A1238
GLU A1292
None
1.28A23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		2pcu CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A 237
GLY A 235
TYR A 238
GLU A 292
None
1.32A22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens)		4 / 5GLU A 173
GLY A 171
TYR A 174
GLU A 169
None
1.20A18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens)		4 / 5ASP A1314
GLU A1316
TYR A1308
GLU A1278
None
1.33A21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		3dlj BETA-ALA-HIS
DIPEPTIDASE
(Homo
sapiens)		4 / 5ASP A 331
GLU A 327
GLY A 328
GLU A 332
UNX  A2007 (-2.7A)
None
None
UNX  A2007 (-4.0A)
1.14A24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.14A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		3mme PG16 HEAVY CHAIN FAB
(Homo
sapiens)		4 / 5ASP H 101
GLU H  95
GLY H  97
TYR H 100
None
1.44A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens)		4 / 5GLU A  90
GLY A 173
TYR A 170
GLU A 327
None
1.38A20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 5GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.03A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		4ixu ARGINASE-2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 275
GLY A 276
TYR A 278
GLU A 281
None
1.49A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 5GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.16A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		5epg ALDEHYDE OXIDASE
(Homo
sapiens)		4 / 5GLU A1170
GLY A1006
TYR A 986
GLU A 948
None
1.35A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 5GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C
(Homo
sapiens)		4 / 5ASP C 422
GLU C 427
TYR C 425
GLU C 418
None
1.45A8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		5zal ENDORIBONUCLEASE
DICER
(Homo
sapiens)		4 / 5ASP A 215
GLY A 212
TYR A 543
GLU A 542
None
1.39A10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1012_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 4ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.18A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		1f8z LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A  23
SER A  19
GLY A  18
ASP A  33
 CA  A  40 (-3.4A)
None
None
CA  A  40 (-3.5A)
1.29A7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		1n3y INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 138
SER A 175
GLY A 205
ASP A 240
None
1.31A20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 118
SER A 117
GLY A 116
ASP A 110
 CA  A1007 (-2.7A)
None
None
None
1.46A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 514
SER A 496
GLY A 495
TRP A 515
None
1.40A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		1tzn ANTHRAX TOXIN
RECEPTOR 2
(Homo
sapiens)		4 / 5ASP a1050
SER a1086
GLY a1116
ASP a1148
None
1.40A18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		3q13 SPONDIN-1
(Homo
sapiens)		4 / 5ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
1.49A20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		5van BETA-KLOTHO
(Homo
sapiens)		4 / 5ASP A 844
SER A 839
GLY A 838
ASP A 846
None
1.19A9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 5ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.19A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		1wuu GALACTOKINASE
(Homo
sapiens)		4 / 6GLU A  43
GLY A 346
LEU A 314
TYR A 318
GLA  A 393 (-3.7A)
GLA  A 393 ( 3.4A)
None
None
0.82A18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		2nt2 PROTEIN PHOSPHATASE
SLINGSHOT HOMOLOG 2
(Homo
sapiens)		4 / 6ASP A 416
GLU A 440
LEU A 415
TYR A 419
None
1.16A16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		3dlj BETA-ALA-HIS
DIPEPTIDASE
(Homo
sapiens)		4 / 6ASP A 331
GLU A 327
GLY A 328
GLU A 332
UNX  A2007 (-2.7A)
None
None
UNX  A2007 (-4.0A)
1.14A24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.14A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		3lm5 SERINE/THREONINE-PRO
TEIN KINASE 17B
(Homo
sapiens)		4 / 6GLU A 144
GLY A 145
LEU A 288
TYR A 147
None
0.98A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		3un9 NLR FAMILY MEMBER X1
(Homo
sapiens)		4 / 6GLU A 960
GLY A 961
LEU A 937
GLU A 968
None
0.87A23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 6GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.01A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		4pbx RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE S
(Homo
sapiens)		4 / 6GLU A 270
GLY A 268
LEU A 272
TYR A 296
None
0.93A22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 6GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		5j6s ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 2
(Homo
sapiens)		4 / 6ASP A 308
GLY A 281
LEU A 304
GLU A 311
None
1.10A19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.27A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.25A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.22A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.32A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.44A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.24A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.39A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.31A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		1qc5 PROTEIN (ALPHA1
BETA1 INTEGRIN)
(Homo
sapiens)		4 / 5ASP B 334
GLU B 426
GLY B 429
GLN B 370
None
1.42A18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		2d7n FILAMIN-C
(Homo
sapiens)		4 / 5ASP A  42
GLU A  23
GLY A  22
GLN A  20
None
1.47A12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens)		4 / 5ASP A  43
GLU A  64
GLY A  62
GLN A  46
None
1.21A20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1
(Homo
sapiens)		4 / 5ASP A 371
GLU A 373
TYR A 374
GLN A 257
None
1.44A19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		3o0t SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PGAM5, MITOCHONDRIAL
(Homo
sapiens)		4 / 5ASP A 200
GLU A 177
TYR A 197
GLN A 196
None
PO4  A   1 (-3.4A)
None
None
0.96A17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		4bkx HISTONE DEACETYLASE
1
(Homo
sapiens)		4 / 5GLU B 184
GLY B 180
TYR B 172
GLN B 260
None
1.49A20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		5i3o BMP-2-INDUCIBLE
PROTEIN KINASE
(Homo
sapiens)		4 / 5ASP A 161
GLY A 192
TYR A 194
GLN A 157
None
1.17A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		1elk TARGET OF MYB1
(Homo
sapiens)		4 / 6CYH A  77
THR A  76
ASN A  80
ILE A  39
None
1.47A17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		1exz STEM CELL FACTOR
(Homo
sapiens)		4 / 6THR A   9
ASN A  11
ASP A  14
ILE A  75
None
1.30A15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		1sjr POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1
(Homo
sapiens)		4 / 6CYH A 114
THR A 115
ASN A 108
ILE A  66
None
1.47A14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		1znm YY1
(Homo
sapiens)		4 / 6CYH A   4
THR A   5
CYH A   9
ILE A  25
 ZN  A  29 ( 2.3A)
None
ZN  A  29 ( 2.3A)
None
1.49A5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2b0o UPLC1
(Homo
sapiens)		4 / 6ASN E 499
CYH E 441
ASP E 443
ILE E 531
None
ZN  E 698 (-2.3A)
None
None
1.50A19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2bx6 XRP2 PROTEIN
(Homo
sapiens)		4 / 6THR A  87
ASN A  88
CYH A 108
ILE A  72
None
1.24A22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2dlg FILAMIN-B
(Homo
sapiens)		4 / 6ASN A  22
CYH A  58
ASP A  20
ILE A  18
None
1.17A16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2iqj STROMAL
MEMBRANE-ASSOCIATED
PROTEIN 1-LIKE
(Homo
sapiens)		4 / 6ASN A  86
CYH A  28
ASP A  30
ILE A 114
None
ZN  A 301 (-2.3A)
None
None
1.49A14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2jnw DNA EXCISION REPAIR
PROTEIN ERCC-1
(Homo
sapiens)		4 / 6CYH A 194
THR A 195
CYH A 189
ILE A 153
None
1.36A15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2jpd DNA EXCISION REPAIR
PROTEIN ERCC-1
(Homo
sapiens)		4 / 6CYH A 194
THR A 195
CYH A 189
ILE A 153
None
1.49A15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2lce B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens)		4 / 6CYH A  48
ASN A  49
CYH A  51
ILE A  67
 ZN  A 300 (-2.3A)
None
ZN  A 300 (-2.3A)
None
1.47A9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2m9y E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens)		4 / 6CYH A 367
ASN A 366
CYH A 347
ILE A 351
 ZN  A 401 (-2.2A)
None
ZN  A 401 (-2.2A)
None
1.20A11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2nmp CYSTATHIONINE
GAMMA-LYASE
(Homo
sapiens)		4 / 6CYH A 229
ASN A 228
ASP A 204
ILE A 183
None
1.49A19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
(Homo
sapiens)		4 / 6CYH B2202
THR B2203
CYH B2343
ILE B2159
 ZN  B 102 (-2.4A)
None
ZN  B 102 (-2.4A)
None
1.30A19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2obv S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1
(Homo
sapiens)		4 / 6CYH A  34
THR A 262
CYH A  60
ILE A  87
None
1.30A21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		2vr2 DIHYDROPYRIMIDINASE
(Homo
sapiens)		4 / 6CYH A 328
THR A 329
ASN A 327
ASP A 326
None
None
None
ZN  A1494 (-2.7A)
1.41A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		3h1v GLUCOKINASE
(Homo
sapiens)		4 / 6CYH X 233
ASN X 254
CYH X 252
ILE X 211
None
GLC  X 500 ( 4.6A)
None
TK1  X 501 (-4.3A)
1.34A20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		3l2p DNA LIGASE 3
(Homo
sapiens)		4 / 6CYH A 628
THR A 733
ASN A 734
ILE A 713
None
1.41A20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		3qj4 RENALASE
(Homo
sapiens)		4 / 6CYH A  65
THR A  64
ASP A 325
ILE A 328
None
1.26A22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		4cdo THIOREDOXIN-LIKE
PROTEIN 4A,
POLYGLUTAMINE-BINDIN
G PROTEIN
(Homo
sapiens)		4 / 6CYH A  79
THR A  80
CYH A  38
ASP A  35
None
1.18A15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		4py4 POLY [ADP-RIBOSE]
POLYMERASE 14
(Homo
sapiens)		4 / 6CYH A1640
THR A1639
ASN A1720
ILE A1797
None
1.28A17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens)		4 / 6THR O 170
ASN O  81
ASP O 106
ILE O 109
NAD  O 501 (-4.1A)
NAD  O 501 (-2.9A)
NAD  O 501 (-2.4A)
None
1.41A22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 2
(Homo
sapiens)		4 / 6CYH I 297
THR I 296
ASN I 474
ILE I 377
None
1.40A15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		5jk7 PROTEIN VPRBP
(Homo
sapiens)		4 / 6CYH C1358
THR C1359
CYH C1099
ILE C1354
None
1.31A21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.26A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.26A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.22A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.44A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.24A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.39A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.30A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens)		4 / 5GLU A 123
GLY A 122
TYR A 125
GLU A 133
None
1.44A20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		1xfe LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A  61
GLY A  54
TYR A  66
GLU A  47
 CA  A 200 (-3.7A)
None
None
CA  A 200 (-3.7A)
1.35A10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		2boa CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A1237
GLY A1235
TYR A1238
GLU A1292
None
1.27A23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		2pcu CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A 237
GLY A 235
TYR A 238
GLU A 292
None
1.31A22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens)		4 / 5GLU A 173
GLY A 171
TYR A 174
GLU A 169
None
1.20A18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.15A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		3mme PG16 HEAVY CHAIN FAB
(Homo
sapiens)		4 / 5ASP H 101
GLU H  95
GLY H  97
TYR H 100
None
1.45A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens)		4 / 5GLU A  90
GLY A 173
TYR A 170
GLU A 327
None
1.37A20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 5GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.02A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		4ixu ARGINASE-2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 275
GLY A 276
TYR A 278
GLU A 281
None
1.49A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 5GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.16A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		5epg ALDEHYDE OXIDASE
(Homo
sapiens)		4 / 5GLU A1170
GLY A1006
TYR A 986
GLU A 948
None
1.35A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 5GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C
(Homo
sapiens)		4 / 5ASP C 422
GLU C 427
TYR C 425
GLU C 418
None
1.46A8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		5zal ENDORIBONUCLEASE
DICER
(Homo
sapiens)		4 / 5ASP A 215
GLY A 212
TYR A 543
GLU A 542
None
1.39A10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		1n3y INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 138
SER A 175
GLY A 205
ASP A 240
None
1.32A20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 118
SER A 117
GLY A 116
ASP A 110
 CA  A1007 (-2.7A)
None
None
None
1.47A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 514
SER A 496
GLY A 495
TRP A 515
None
1.39A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		1tzn ANTHRAX TOXIN
RECEPTOR 2
(Homo
sapiens)		4 / 5ASP a1050
SER a1086
GLY a1116
ASP a1148
None
1.41A18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		3q13 SPONDIN-1
(Homo
sapiens)		4 / 5ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
1.50A20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		5van BETA-KLOTHO
(Homo
sapiens)		4 / 5ASP A 844
SER A 839
GLY A 838
ASP A 846
None
1.20A9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 5ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.19A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		5i3o BMP-2-INDUCIBLE
PROTEIN KINASE
(Homo
sapiens)		4 / 4ASP A 161
GLY A 192
TYR A 194
GLN A 157
None
1.27A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens)		3 / 3ASP A 486
GLY A 666
TYR A 461
None
0.77A19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		2q3z TRANSGLUTAMINASE 2
(Homo
sapiens)		3 / 3ASP A 389
GLY A 367
TYR A 388
None
SO4  A 688 (-3.1A)
None
0.68A20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		3lpp SUCRASE-ISOMALTASE
(Homo
sapiens)		3 / 3ASP A 524
GLY A 286
TYR A 523
None
0.79A19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1
(Homo
sapiens)		3 / 3ASP A  17
GLY A  63
TYR A 432
None
EDO  A1447 ( 4.1A)
EDO  A1447 (-4.2A)
0.77A20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1
(Homo
sapiens)		3 / 3ASP A  17
GLY A  65
TYR A 432
None
None
EDO  A1447 (-4.2A)
0.46A20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		4nzr PGT135 HEAVY CHAIN
PROTEIN M TD
(Homo
sapiens;
Mycoplasma
genitalium)		3 / 3ASP M 188
GLY H 169
TYR M 187
None
0.70A21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		5gwn PROTEIN RCC2
(Homo
sapiens)		3 / 3ASP A 369
GLY A 358
TYR A 283
None
0.80A20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		6chd LYSINE--TRNA LIGASE
(Homo
sapiens)		3 / 3ASP A 560
GLY A 377
TYR A 373
None
SO4  A 606 (-3.3A)
None
0.80A11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		3 / 3ASP A 273
GLY A 276
TYR A 235
 CA  A 300 (-3.1A)
CA  A 300 ( 4.5A)
None
0.73A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 118
SER A 117
GLY A 116
ASP A 110
 CA  A1007 (-2.7A)
None
None
None
1.47A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A 514
SER A 496
GLY A 495
TRP A 515
None
1.39A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		1tzn ANTHRAX TOXIN
RECEPTOR 2
(Homo
sapiens)		4 / 5ASP a1050
SER a1086
GLY a1116
ASP a1148
None
1.41A18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		5van BETA-KLOTHO
(Homo
sapiens)		4 / 5ASP A 844
SER A 839
GLY A 838
ASP A 846
None
1.21A9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 5ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.18A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.28A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.25A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.23A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.43A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.24A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.39A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.31A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		2aw2 B AND T LYMPHOCYTE
ATTENUATOR
TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
14
(Homo
sapiens)		4 / 5GLU B  31
GLY B  30
TYR A  39
GLN A  37
None
1.30A13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		2d7n FILAMIN-C
(Homo
sapiens)		4 / 5ASP A  42
GLU A  23
GLY A  22
GLN A  20
None
1.45A12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens)		4 / 5ASP A  43
GLU A  64
GLY A  62
GLN A  46
None
1.18A20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		2r55 STAR-RELATED LIPID
TRANSFER PROTEIN 5
(Homo
sapiens)		4 / 5GLU A  32
GLY A  35
TYR A 201
GLN A 205
None
1.09A17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		3o0t SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PGAM5, MITOCHONDRIAL
(Homo
sapiens)		4 / 5ASP A 200
GLU A 177
TYR A 197
GLN A 196
None
PO4  A   1 (-3.4A)
None
None
1.03A17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		3pdf DIPEPTIDYL PEPTIDASE
1
(Homo
sapiens)		4 / 5ASP A 304
GLU A 275
GLY A 273
GLN A 262
None
1.42A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		5dtr HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC
(Homo
sapiens)		4 / 5ASP A 142
GLU A 138
GLY A 137
GLN A 172
None
1.40A21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		5i3o BMP-2-INDUCIBLE
PROTEIN KINASE
(Homo
sapiens)		4 / 5ASP A 161
GLY A 192
TYR A 194
GLN A 157
None
1.20A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		1o5t TRYPTOPHANYL-TRNA
SYNTHETASE
(Homo
sapiens)		4 / 5GLU A 429
GLY A 428
TYR A 420
ASP A 397
None
0.94A21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE
(Homo
sapiens)		4 / 5GLU A  16
GLY A  13
TYR A 152
ASP A  96
None
O16  A3201 ( 3.7A)
O16  A3201 (-4.9A)
O16  A3201 ( 4.8A)
1.32A17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		2qqm NEUROPILIN-1
(Homo
sapiens)		4 / 5ASP A 428
GLU A 277
GLY A 423
TYR A 429
EDO  A 607 (-2.7A)
None
None
None
1.33A19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		2wek ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 5GLU A 340
GLY A 341
TYR A 355
ASP A 333
None
1.04A22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		2wpm COAGULATION FACTOR
IXA HEAVY CHAIN
(Homo
sapiens)		4 / 5GLU S 217
GLY S 216
TYR S  99
ASP S 102
None
1.35A20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN
(Homo
sapiens)		4 / 5ASP A 257
GLU A 256
GLY A 228
ASP A 250
None
None
ANP  A 408 (-3.6A)
None
1.39A20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN
(Homo
sapiens)		4 / 5GLU A 316
GLY A 315
TYR A 313
ASP A 281
None
1.20A20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		3tdu CULLIN-1
DCN1-LIKE PROTEIN 1
(Homo
sapiens)		4 / 5ASP A 241
GLU A 233
GLY A 234
ASP C 754
None
1.27A18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		3tkr PEROXIREDOXIN-4
(Homo
sapiens)		4 / 5ASP A 170
GLY A 172
TYR A  73
ASP A 202
None
1.43A18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
(Homo
sapiens)		4 / 5ASP A 305
GLU A 688
GLY A 398
ASP A 301
None
1.19A17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		4kbo STRESS-70 PROTEIN,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5ASP A 277
GLU A 276
GLY A 248
ASP A 270
None
1.34A23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		4p42 EXTENDED
SYNAPTOTAGMIN-2
(Homo
sapiens)		4 / 5ASP A 432
GLU A 404
GLY A 382
ASP A 436
None
1.35A21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		5jz8 ASPARTYL/ASPARAGINYL
BETA-HYDROXYLASE
(Homo
sapiens)		4 / 5GLU A 403
GLY A 400
TYR A 405
ASP A 386
None
1.31A20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens)		4 / 5GLU A 123
GLY A 122
TYR A 125
GLU A 133
None
1.44A20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		1xfe LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 5ASP A  61
GLY A  54
TYR A  66
GLU A  47
 CA  A 200 (-3.7A)
None
None
CA  A 200 (-3.7A)
1.33A10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		2boa CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A1237
GLY A1235
TYR A1238
GLU A1292
None
1.28A23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		2pcu CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A 237
GLY A 235
TYR A 238
GLU A 292
None
1.33A22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens)		4 / 5GLU A 173
GLY A 171
TYR A 174
GLU A 169
None
1.20A18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		3dlj BETA-ALA-HIS
DIPEPTIDASE
(Homo
sapiens)		4 / 5ASP A 331
GLU A 327
GLY A 328
GLU A 332
UNX  A2007 (-2.7A)
None
None
UNX  A2007 (-4.0A)
1.14A24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.14A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		3mme PG16 HEAVY CHAIN FAB
(Homo
sapiens)		4 / 5ASP H 101
GLU H  95
GLY H  97
TYR H 100
None
1.45A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens)		4 / 5GLU A  90
GLY A 173
TYR A 170
GLU A 327
None
1.38A20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 5GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.03A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		4ixu ARGINASE-2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 275
GLY A 276
TYR A 278
GLU A 281
None
1.48A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 5GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.16A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		5epg ALDEHYDE OXIDASE
(Homo
sapiens)		4 / 5GLU A1170
GLY A1006
TYR A 986
GLU A 948
None
1.35A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 5GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C
(Homo
sapiens)		4 / 5ASP C 422
GLU C 427
TYR C 425
GLU C 418
None
1.44A8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		5zal ENDORIBONUCLEASE
DICER
(Homo
sapiens)		4 / 5ASP A 215
GLY A 212
TYR A 543
GLU A 542
None
1.39A10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE501_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 4ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.17A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		1wuu GALACTOKINASE
(Homo
sapiens)		4 / 6GLU A  43
GLY A 346
LEU A 314
TYR A 318
GLA  A 393 (-3.7A)
GLA  A 393 ( 3.4A)
None
None
0.82A18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		2nt2 PROTEIN PHOSPHATASE
SLINGSHOT HOMOLOG 2
(Homo
sapiens)		4 / 6ASP A 416
GLU A 440
LEU A 415
TYR A 419
None
1.16A16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.13A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		3lm5 SERINE/THREONINE-PRO
TEIN KINASE 17B
(Homo
sapiens)		4 / 6GLU A 144
GLY A 145
LEU A 288
TYR A 147
None
0.98A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		3un9 NLR FAMILY MEMBER X1
(Homo
sapiens)		4 / 6GLU A 960
GLY A 961
LEU A 937
GLU A 968
None
0.86A23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		4bv6 APOPTOSIS-INDUCING
FACTOR 1,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6GLY A 288
LEU A 175
TYR A 170
GLU A 167
None
FAD  A1449 ( 4.7A)
None
None
1.16A22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		4c8d LYSINE-SPECIFIC
DEMETHYLASE 3B
(Homo
sapiens)		4 / 6ASP A1679
GLY A1419
LEU A1416
GLU A1608
None
1.15A21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 6GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.02A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		4pbx RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE S
(Homo
sapiens)		4 / 6GLU A 270
GLY A 268
LEU A 272
TYR A 296
None
0.93A22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 6GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.16A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 6GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		5j6s ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 2
(Homo
sapiens)		4 / 6ASP A 308
GLY A 281
LEU A 304
GLU A 311
None
1.10A19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.28A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.25A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.23A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.44A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.23A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.40A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.31A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		2aw2 B AND T LYMPHOCYTE
ATTENUATOR
TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
14
(Homo
sapiens)		4 / 5GLU B  31
GLY B  30
TYR A  39
GLN A  37
None
1.28A13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		2d7n FILAMIN-C
(Homo
sapiens)		4 / 5ASP A  42
GLU A  23
GLY A  22
GLN A  20
None
1.48A12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens)		4 / 5ASP A  43
GLU A  64
GLY A  62
GLN A  46
None
1.24A20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		3o0t SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PGAM5, MITOCHONDRIAL
(Homo
sapiens)		4 / 5ASP A 200
GLU A 177
TYR A 197
GLN A 196
None
PO4  A   1 (-3.4A)
None
None
1.06A17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		3pdf DIPEPTIDYL PEPTIDASE
1
(Homo
sapiens)		4 / 5ASP A 304
GLU A 275
GLY A 273
GLN A 262
None
1.39A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		5dtr HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC
(Homo
sapiens)		4 / 5ASP A 142
GLU A 138
GLY A 137
GLN A 172
None
1.44A21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		5i3o BMP-2-INDUCIBLE
PROTEIN KINASE
(Homo
sapiens)		4 / 5ASP A 161
GLY A 192
TYR A 194
GLN A 157
None
1.28A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		5i4e MYOSIN-14,ALPHA-ACTI
NIN A
(Dictyostelium
discoideum;
Homo
sapiens)		4 / 5GLU A 199
GLY A 198
TYR A 599
GLN A 503
None
1.44A17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		1a4i METHYLENETETRAHYDROF
OLATE DEHYDROGENASE
/
METHENYLTETRAHYDROFO
LATE CYCLOHYDROLASE
(Homo
sapiens)		4 / 6CYH A 147
THR A 148
GLY A 126
ASP A 125
None
NDP  A 302 (-3.6A)
None
None
1.19A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		4az3 LYSOSOMAL PROTECTIVE
PROTEIN 20 KDA CHAIN
LYSOSOMAL PROTECTIVE
PROTEIN 32 KDA CHAIN
(Homo
sapiens)		4 / 6CYH B 375
ASN A 178
GLY A 179
ASP B 380
 CD  B1454 (-1.9A)
None
None
None
1.12A20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		4cdo THIOREDOXIN-LIKE
PROTEIN 4A,
POLYGLUTAMINE-BINDIN
G PROTEIN
(Homo
sapiens)		4 / 6CYH A  79
THR A  80
CYH A  38
ASP A  35
None
1.17A15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		4tnu ASPARTOACYLASE
(Homo
sapiens)		4 / 6CYH A  61
THR A  62
ASN A  23
GLY A 185
None
1.26A20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		4u7t DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens)		4 / 6CYH A 554
ASN A 551
CYH A 549
GLY A 550
 ZN  A1003 (-2.2A)
None
ZN  A1003 (-2.5A)
None
1.38A21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		5i6v TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11
(Homo
sapiens)		4 / 6THR A  59
ASN A  58
GLY A  39
ASP A  40
None
1.09A20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		5lnc VACUOLAR TRANSPORTER
CHAPERONE 4,CORE
HISTONE MACRO-H2A.1
(Homo
sapiens;
Saccharomyces
cerevisiae)		4 / 6CYH A 274
THR A 217
ASN A 275
GLY A 257
None
1.36A22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		5x94 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11
(Homo
sapiens)		4 / 6THR A  59
ASN A  58
GLY A  39
ASP A  40
None
1.07A21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF501_1
(HEMOLYTIC LECTIN
CEL-III)		1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens)		4 / 4ASP A 514
SER A 496
GLY A 495
TRP A 515
None
1.38A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF501_1
(HEMOLYTIC LECTIN
CEL-III)		3q13 SPONDIN-1
(Homo
sapiens)		4 / 4ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
1.50A20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		1wuu GALACTOKINASE
(Homo
sapiens)		4 / 6GLU A  43
GLY A 346
LEU A 314
TYR A 318
GLA  A 393 (-3.7A)
GLA  A 393 ( 3.4A)
None
None
0.80A18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		2nt2 PROTEIN PHOSPHATASE
SLINGSHOT HOMOLOG 2
(Homo
sapiens)		4 / 6ASP A 416
GLU A 440
LEU A 415
TYR A 419
None
1.15A16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		3dlj BETA-ALA-HIS
DIPEPTIDASE
(Homo
sapiens)		4 / 6ASP A 331
GLU A 327
GLY A 328
GLU A 332
UNX  A2007 (-2.7A)
None
None
UNX  A2007 (-4.0A)
1.13A24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.15A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		3lm5 SERINE/THREONINE-PRO
TEIN KINASE 17B
(Homo
sapiens)		4 / 6GLU A 144
GLY A 145
LEU A 288
TYR A 147
None
0.97A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		3un9 NLR FAMILY MEMBER X1
(Homo
sapiens)		4 / 6GLU A 960
GLY A 961
LEU A 937
GLU A 968
None
0.86A23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		4c8d LYSINE-SPECIFIC
DEMETHYLASE 3B
(Homo
sapiens)		4 / 6ASP A1679
GLY A1419
LEU A1416
GLU A1608
None
1.16A21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 6GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.02A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		4pbx RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE S
(Homo
sapiens)		4 / 6GLU A 270
GLY A 268
LEU A 272
TYR A 296
None
0.91A22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		4q9z HUMAN PROTEIN KINASE
C THETA
(Homo
sapiens)		4 / 6GLU A 428
GLY A 524
LEU A 432
GLU A 528
None
1.17A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 6GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.14A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 6GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.10A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		5j6s ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 2
(Homo
sapiens)		4 / 6ASP A 308
GLY A 281
LEU A 304
GLU A 311
None
1.10A19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.27A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.23A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.21A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.18A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.44A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.24A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.40A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.31A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		1t0p INTEGRIN ALPHA-L
(Homo
sapiens)		4 / 6THR A 243
ASN A 207
GLY A 210
ILE A 236
None
0.90A17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens)		4 / 6THR A 657
ASN A 670
GLY A 393
ILE A 707
None
0.97A17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		3eh2 PROTEIN TRANSPORT
PROTEIN SEC24C
(Homo
sapiens)		4 / 6ASN A 473
CYH A 504
GLY A 477
ILE A 434
None
0.98A18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		3via PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY B MEMBER 2
(Homo
sapiens)		4 / 6THR A 111
ASN A 112
GLY A  32
ILE A  81
None
1.03A13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		4b4c CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1
(Homo
sapiens)		4 / 6ASN A1174
CYH A1176
GLY A1175
ILE A1135
None
1.04A18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		4ye4 HT593.1 GP120
LIGHT CHAIN OF HJ16
(Homo
sapiens;
Human
immunodeficiency
virus)		4 / 6THR L 101
ASN G 462
GLY G 466
ILE G 469
None
0.99A20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5e6s INTEGRIN ALPHA-L
(Homo
sapiens)		4 / 6THR A 243
ASN A 207
GLY A 210
ILE A 236
None
0.88A18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5ebb ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3A
(Homo
sapiens)		4 / 6ASN A 151
GLY A 150
ASP A 153
ILE A 129
MLI  A 706 ( 2.6A)
None
None
None
1.04A21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5k10 ISOCITRATE
DEHYDROGENASE [NADP]
CYTOPLASMIC
(Homo
sapiens)		4 / 6THR A  98
ASN A 101
GLY A 104
ILE A  64
None
1.02A22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5kdi PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 8
(Homo
sapiens)		4 / 6THR A 420
ASN A 424
GLY A 425
ILE A 429
None
1.04A10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5vm9 PROTEIN ARGONAUTE-3
(Homo
sapiens)		4 / 6THR A 600
GLY A 671
ASP A 670
ILE A 800
None
0.98A19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		5wea PROTEIN ARGONAUTE-2
(Homo
sapiens)		4 / 6THR A 599
GLY A 670
ASP A 669
ILE A 799
None
0.74A11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG501_1
(HEMOLYTIC LECTIN
CEL-III)		5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1
(Homo
sapiens)		4 / 4ASP A 575
GLY A 577
TRP A 574
ASP A 571
None
1.19A11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		1g82 FIBROBLAST GROWTH
FACTOR 9
(Homo
sapiens)		4 / 5GLU A 123
GLY A 122
TYR A 125
GLU A 133
None
1.44A20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		2boa CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A1237
GLY A1235
TYR A1238
GLU A1292
None
1.27A23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		2pcu CARBOXYPEPTIDASE A4
(Homo
sapiens)		4 / 5GLU A 237
GLY A 235
TYR A 238
GLU A 292
None
1.32A22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens)		4 / 5GLU A 173
GLY A 171
TYR A 174
GLU A 169
None
1.20A18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 332
GLY A 331
TYR A 329
GLU A 268
None
1.13A20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		3mme PG16 HEAVY CHAIN FAB
(Homo
sapiens)		4 / 5ASP H 101
GLU H  95
GLY H  97
TYR H 100
None
1.45A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		3ut3 PLASMINOGEN
ACTIVATOR INHIBITOR
1
(Homo
sapiens)		4 / 5GLU A  90
GLY A 173
TYR A 170
GLU A 327
None
1.38A20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)		4 / 5GLU B 220
GLY B 221
TYR B 318
GLU A 324
None
1.01A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		4ixu ARGINASE-2,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLU A 275
GLY A 276
TYR A 278
GLU A 281
None
1.48A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		4zey NUCLEAR
RECEPTOR-BINDING
FACTOR 2
(Homo
sapiens)		4 / 5GLU A   5
GLY A   6
TYR A  40
GLU A  43
None
1.16A10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		5epg ALDEHYDE OXIDASE
(Homo
sapiens)		4 / 5GLU A1170
GLY A1006
TYR A 986
GLU A 948
None
1.35A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		5gvs PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41
(Homo
sapiens)		4 / 5GLU A 256
GLY A 313
TYR A 259
GLU A 247
None
1.13A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C
(Homo
sapiens)		4 / 5ASP C 422
GLU C 427
TYR C 425
GLU C 418
None
1.46A8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		5zal ENDORIBONUCLEASE
DICER
(Homo
sapiens)		4 / 5ASP A 215
GLY A 212
TYR A 543
GLU A 542
None
1.38A10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6
(Homo
sapiens)		3 / 3ASP A 486
GLY A 666
TYR A 461
None
0.77A19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		2q3z TRANSGLUTAMINASE 2
(Homo
sapiens)		3 / 3ASP A 389
GLY A 367
TYR A 388
None
SO4  A 688 (-3.1A)
None
0.68A20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		3lpp SUCRASE-ISOMALTASE
(Homo
sapiens)		3 / 3ASP A 524
GLY A 286
TYR A 523
None
0.79A19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1
(Homo
sapiens)		3 / 3ASP A  17
GLY A  63
TYR A 432
None
EDO  A1447 ( 4.1A)
EDO  A1447 (-4.2A)
0.77A20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1
(Homo
sapiens)		3 / 3ASP A  17
GLY A  65
TYR A 432
None
None
EDO  A1447 (-4.2A)
0.46A20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		4nzr PGT135 HEAVY CHAIN
PROTEIN M TD
(Homo
sapiens;
Mycoplasma
genitalium)		3 / 3ASP M 188
GLY H 169
TYR M 187
None
0.70A21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		5gwn PROTEIN RCC2
(Homo
sapiens)		3 / 3ASP A 369
GLY A 358
TYR A 283
None
0.80A20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE
(Homo
sapiens)		3 / 3ASP A 108
GLY A 112
TYR A 117
SAH  A 305 ( 4.3A)
SAH  A 305 (-3.4A)
SAH  A 305 ( 4.8A)
0.80A11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		6chd LYSINE--TRNA LIGASE
(Homo
sapiens)		3 / 3ASP A 560
GLY A 377
TYR A 373
None
SO4  A 606 (-3.3A)
None
0.80A11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		3 / 3ASP A 273
GLY A 276
TYR A 235
 CA  A 300 (-3.1A)
CA  A 300 ( 4.5A)
None
0.73A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)
(Homo
sapiens)		4 / 5ASP A 569
VAL A 568
GLY A 567
ASP A 633
None
1.27A18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		1kcw CERULOPLASMIN
(Homo
sapiens)		4 / 5VAL A 764
GLY A 873
TYR A 813
ASP A 869
None
1.26A17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		2ppl PANCREATIC
LIPASE-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 5VAL A 360
GLY A 359
TYR A 402
ASP A 312
None
1.22A23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		4hfu FAB 8M2 HEAVY CHAIN
(Homo
sapiens)		4 / 5ASP H 101
VAL H  95
GLY H  97
TYR H 100
None
1.31A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens)		4 / 5ASP A  62
VAL A  63
GLY A  31
ASP A  33
None
1.20A16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		4nen INTEGRIN ALPHA-X
(Homo
sapiens)		4 / 5ASP A 515
VAL A 540
GLY A 539
ASP A 511
 CA  A1113 (-2.6A)
None
None
CA  A1113 (-3.2A)
1.19A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 5VAL A 371
GLY A 370
TYR A 444
ASP A 435
None
1.45A19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens)		4 / 5VAL A 182
GLY A 181
TYR A 184
ASP A 211
None
1.23A18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		5jiu RAN-BINDING PROTEIN
9
(Homo
sapiens)		4 / 5VAL A 239
GLY A 238
TYR A 313
ASP A 173
None
1.38A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens)		4 / 5ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
1.31A11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		2aw2 B AND T LYMPHOCYTE
ATTENUATOR
TUMOR NECROSIS
FACTOR RECEPTOR
SUPERFAMILY MEMBER
14
(Homo
sapiens)		4 / 5GLU B  31
GLY B  30
TYR A  39
GLN A  37
None
1.34A13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		2d7n FILAMIN-C
(Homo
sapiens)		4 / 5ASP A  42
GLU A  23
GLY A  22
GLN A  20
None
1.45A12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		2oby PUTATIVE QUINONE
OXIDOREDUCTASE
(Homo
sapiens)		4 / 5ASP A  43
GLU A  64
GLY A  62
GLN A  46
None
1.29A20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		2r55 STAR-RELATED LIPID
TRANSFER PROTEIN 5
(Homo
sapiens)		4 / 5GLU A  32
GLY A  35
TYR A 201
GLN A 205
None
1.14A17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		3pdf DIPEPTIDYL PEPTIDASE
1
(Homo
sapiens)		4 / 5ASP A 304
GLU A 275
GLY A 273
GLN A 262
None
1.42A21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		4bkx HISTONE DEACETYLASE
1
(Homo
sapiens)		4 / 5GLU B 184
GLY B 180
TYR B 172
GLN B 260
None
1.49A20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		5dtr HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC
(Homo
sapiens)		4 / 5ASP A 142
GLU A 138
GLY A 137
GLN A 172
None
1.48A21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		5i3o BMP-2-INDUCIBLE
PROTEIN KINASE
(Homo
sapiens)		4 / 5ASP A 161
GLY A 192
TYR A 194
GLN A 157
None
1.20A18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		1hlc HUMAN LECTIN
(Homo
sapiens)		7 / 7HIS A  45
ASN A  47
ARG A  49
ASN A  58
TRP A  65
GLU A  68
ARG A  70
GAL  A 998 (-3.8A)
GAL  A 998 (-4.1A)
BGC  A 999 ( 2.7A)
GAL  A 998 (-3.6A)
GAL  A 998 (-3.7A)
BGC  A 999 ( 2.8A)
BGC  A 999 (-4.3A)
0.50A26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		1lpb LIPASE
(Homo
sapiens)		4 / 7ASN B 100
ARG B  68
ASN B  63
GLU B  44
None
1.07A8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC
(Homo
sapiens)		4 / 7HIS A 297
ARG A 290
GLU A 306
ARG A 289
None
1.29A13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		2n7a SIALIC ACID-BINDING
IG-LIKE LECTIN 8
(Homo
sapiens)		4 / 7HIS A  47
ASN A  67
GLU A 111
ARG A 109
None
1.24A19.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		2yro GALECTIN-8
(Homo
sapiens)		4 / 7HIS A  61
ASN A  63
ASN A  74
TRP A  81
None
0.71A30.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		2zhl GALECTIN-9
(Homo
sapiens)		4 / 7HIS A  61
ASN A  63
ARG A  44
TRP A  82
GAL  A1493 ( 3.9A)
GAL  A1493 (-3.6A)
NAG  A1491 (-4.6A)
GAL  A1493 (-3.7A)
1.10A28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		2zhl GALECTIN-9
(Homo
sapiens)		7 / 7HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A1493 ( 3.9A)
GAL  A1493 (-3.6A)
NAG  A1494 ( 2.8A)
GAL  A1493 (-3.9A)
GAL  A1493 (-3.7A)
NAG  A1494 ( 2.7A)
NAG  A1494 (-4.0A)
0.39A28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		3ayd GALECTIN-3
(Homo
sapiens)		7 / 7HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
GAL  A 253 (-3.7A)
GAL  A 253 (-4.1A)
A2G  A 252 ( 3.1A)
GAL  A 253 (-3.9A)
GAL  A 253 (-3.5A)
A2G  A 252 (-3.0A)
GAL  A 256 ( 3.8A)
0.21A93.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		3nv3 GALECTIN 9 SHORT
ISOFORM VARIANT
(Homo
sapiens)		7 / 7HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 501 (-3.9A)
GAL  A 501 (-3.8A)
NAG  A 502 ( 2.7A)
GAL  A 501 (-3.8A)
GAL  A 501 (-3.6A)
NAG  A 502 ( 2.7A)
NAG  A 502 (-4.0A)
0.24A26.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		3ojb GALECTIN-8
(Homo
sapiens)		5 / 7HIS A  53
ASN A  55
ASN A  66
GLU A  76
ARG A  78
None
0.86A32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		3ojb GALECTIN-8
(Homo
sapiens)		5 / 7HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
None
0.49A32.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		3wv6 GALECTIN-9
(Homo
sapiens)		4 / 7HIS A  61
ASN A  63
ARG A  44
TRP A  82
GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
GAL  A 402 ( 4.9A)
GAL  A 402 (-3.7A)
1.11A15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 7HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
0.37A15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 7HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
0.24A15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		3zxe GALECTIN-7
(Homo
sapiens)		7 / 7HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
ARG A  74
PGZ  A   1 (-3.9A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-3.6A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-4.0A)
PGZ  A   1 (-3.5A)
None
0.62A25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4bmb GALECTIN-8
(Homo
sapiens)		6 / 7HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A1155 (-3.9A)
LAT  A1155 (-3.9A)
LAT  A1155 (-2.7A)
LAT  A1155 (-3.9A)
LAT  A1155 (-3.6A)
LAT  A1155 (-3.0A)
0.17A28.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4boc DNA-DIRECTED RNA
POLYMERASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 7HIS A1030
TRP A1026
GLU A1027
ARG A 976
None
1.26A5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4fqz GALECTIN-8
(Homo
sapiens)		5 / 7HIS A  65
ASN A  67
ARG A  45
ASN A  79
TRP A  86
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
GAL  A 401 (-2.8A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
1.33A17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4fqz GALECTIN-8
(Homo
sapiens)		6 / 7HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
BGC  A 402 ( 2.5A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
BGC  A 402 ( 3.3A)
0.30A17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4fqz GALECTIN-8
(Homo
sapiens)		7 / 7HIS A 229
ASN A 231
ARG A 233
ASN A 242
TRP A 249
GLU A 252
ARG A 254
None
0.43A17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4xzp GALECTIN-4
(Homo
sapiens)		6 / 7HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
None
0.45A29.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		4y1y GALECTIN-1
(Homo
sapiens)		7 / 7HIS A  44
ASN A  46
ARG A  48
ASN A  61
TRP A  68
GLU A  71
ARG A  73
GAL  A 201 (-3.9A)
GAL  A 201 (-4.4A)
6S2  A 202 (-2.8A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 4.1A)
6S2  A 202 (-2.6A)
6S2  A 202 (-3.8A)
0.44A33.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4y26 GALECTIN-7
(Homo
sapiens)		7 / 7HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
ARG A  74
GAL  A 201 (-3.9A)
GAL  A 201 (-4.1A)
6S2  A 202 (-2.9A)
GAL  A 201 (-3.7A)
GAL  A 201 (-3.5A)
6S2  A 202 (-2.8A)
6S2  A 202 (-3.5A)
0.61A25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4ym3 GALECTIN-4
(Homo
sapiens)		6 / 7HIS A 236
ASN A 238
ARG A 240
ASN A 249
TRP A 256
GLU A 259
LAT  A 401 (-3.9A)
LAT  A 401 (-4.0A)
LAT  A 401 (-2.6A)
LAT  A 401 (-3.7A)
LAT  A 401 ( 3.8A)
LAT  A 401 (-3.1A)
0.19A24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		4zwe DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
(Homo
sapiens)		4 / 7HIS A 210
ASN A 207
ARG A 206
GLU A 234
DGT  A 701 (-4.5A)
DGT  A 701 (-3.6A)
DGT  A 701 ( 4.2A)
None
1.13A9.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5dux GALECTIN-4
(Homo
sapiens)		4 / 7ASN B  77
TRP B  84
GLU B  87
ARG B  89
LAT  B 201 (-3.9A)
LAT  B 201 ( 3.8A)
LAT  B 201 (-2.4A)
LAT  B 201 ( 3.7A)
1.10A31.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5dux GALECTIN-4
(Homo
sapiens)		6 / 7HIS B  63
ASN B  65
ARG B  67
ASN B  77
TRP B  84
GLU B  87
LAT  B 201 (-3.9A)
LAT  B 201 (-3.8A)
LAT  B 201 (-2.6A)
LAT  B 201 (-3.9A)
LAT  B 201 ( 3.8A)
LAT  B 201 (-2.4A)
0.21A31.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		5gzg GALECTIN-8
(Homo
sapiens)		6 / 7HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A 201 (-3.9A)
LAT  A 201 (-4.2A)
LAT  A 201 (-2.3A)
LAT  A 201 (-3.6A)
LAT  A 201 (-3.7A)
LAT  A 201 (-3.0A)
0.17A21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5h9p GALECTIN-3
(Homo
sapiens)		4 / 7ARG A 186
ASN A 166
GLU A 165
ARG A 162
TD2  A 301 (-3.9A)
None
TD2  A 301 ( 4.9A)
TD2  A 301 (-2.8A)
1.29A80.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5h9p GALECTIN-3
(Homo
sapiens)		7 / 7HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
TD2  A 301 (-3.8A)
TD2  A 301 (-4.0A)
TD2  A 301 (-2.8A)
TD2  A 301 (-3.8A)
TD2  A 301 ( 3.7A)
TD2  A 301 (-2.9A)
TD2  A 301 (-3.9A)
0.13A80.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5nfb GALECTIN-3
(Homo
sapiens)		4 / 7ARG A 186
ASN A 166
GLU A 165
ARG A 162
8VT  A 301 (-3.4A)
None
8VT  A 301 (-3.5A)
8VT  A 301 (-2.7A)
1.28A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5nfb GALECTIN-3
(Homo
sapiens)		7 / 7HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
8VT  A 301 (-3.9A)
8VT  A 301 (-4.0A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.8A)
8VT  A 301 ( 3.7A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.4A)
0.09A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens)		4 / 7HIS A  53
ASN A  65
TRP A  72
GLU A  75
GOL  A 201 (-3.5A)
GOL  A 201 (-3.7A)
GOL  A 201 (-3.0A)
GOL  A 201 (-2.8A)
0.67A32.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens)		4 / 7ARG C 186
ASN C 166
GLU C 165
ARG C 162
LAT  C 301 (-4.0A)
None
LAT  C 301 ( 4.7A)
LAT  C 301 (-2.7A)
1.16Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens)		7 / 7HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
0.27Aundetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		1hlc HUMAN LECTIN
(Homo
sapiens)		7 / 8HIS A  45
ASN A  47
ARG A  49
ASN A  58
TRP A  65
GLU A  68
ARG A  70
GAL  A 998 (-3.8A)
GAL  A 998 (-4.1A)
BGC  A 999 ( 2.7A)
GAL  A 998 (-3.6A)
GAL  A 998 (-3.7A)
BGC  A 999 ( 2.8A)
BGC  A 999 (-4.3A)
0.55A30.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		1lpb LIPASE
(Homo
sapiens)		4 / 8ASN B 100
ARG B  68
ASN B  63
GLU B  44
None
1.10A12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		2nsm CARBOXYPEPTIDASE N
CATALYTIC CHAIN
(Homo
sapiens)		4 / 8ASN A 194
HIS A  66
ASN A 203
GLU A 288
None
SO4  A1776 (-4.2A)
None
SO4  A1776 ( 4.7A)
1.04A12.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		2yro GALECTIN-8
(Homo
sapiens)		4 / 8ASN A  63
ASN A  74
TRP A  81
GLU A  84
None
0.84A35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		2yro GALECTIN-8
(Homo
sapiens)		5 / 8HIS A  61
ASN A  63
ASN A  74
TRP A  81
ARG A  86
None
0.76A35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		2zhl GALECTIN-9
(Homo
sapiens)		4 / 8HIS A  61
ASN A  63
ARG A  44
TRP A  82
GAL  A1493 ( 3.9A)
GAL  A1493 (-3.6A)
NAG  A1491 (-4.6A)
GAL  A1493 (-3.7A)
1.07A32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		2zhl GALECTIN-9
(Homo
sapiens)		7 / 8HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A1493 ( 3.9A)
GAL  A1493 (-3.6A)
NAG  A1494 ( 2.8A)
GAL  A1493 (-3.9A)
GAL  A1493 (-3.7A)
NAG  A1494 ( 2.7A)
NAG  A1494 (-4.0A)
0.41A32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		3ayd GALECTIN-3
(Homo
sapiens)		7 / 8HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
GAL  A 253 (-3.7A)
GAL  A 253 (-4.1A)
A2G  A 252 ( 3.1A)
GAL  A 253 (-3.9A)
GAL  A 253 (-3.5A)
A2G  A 252 (-3.0A)
GAL  A 256 ( 3.8A)
0.43A34.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		3nv3 GALECTIN 9 SHORT
ISOFORM VARIANT
(Homo
sapiens)		7 / 8HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 501 (-3.9A)
GAL  A 501 (-3.8A)
NAG  A 502 ( 2.7A)
GAL  A 501 (-3.8A)
GAL  A 501 (-3.6A)
NAG  A 502 ( 2.7A)
NAG  A 502 (-4.0A)
0.41A23.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		3ojb GALECTIN-8
(Homo
sapiens)		5 / 8HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
None
0.48A36.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		3wv6 GALECTIN-9
(Homo
sapiens)		4 / 8HIS A  61
ASN A  63
ARG A  44
TRP A  82
GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
GAL  A 402 ( 4.9A)
GAL  A 402 (-3.7A)
1.04A12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 8HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
0.38A12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 8HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
0.54A12.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		3zxe GALECTIN-7
(Homo
sapiens)		6 / 8HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
PGZ  A   1 (-3.9A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-3.6A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-4.0A)
PGZ  A   1 (-3.5A)
0.25A38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		3zxe GALECTIN-7
(Homo
sapiens)		6 / 8HIS A  49
ASN A  51
ARG A  53
TRP A  69
GLU A  72
ARG A  74
PGZ  A   1 (-3.9A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-3.6A)
PGZ  A   1 (-4.0A)
PGZ  A   1 (-3.5A)
None
0.62A38.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4bmb GALECTIN-8
(Homo
sapiens)		6 / 8HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A1155 (-3.9A)
LAT  A1155 (-3.9A)
LAT  A1155 (-2.7A)
LAT  A1155 (-3.9A)
LAT  A1155 (-3.6A)
LAT  A1155 (-3.0A)
0.42A29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		5 / 8HIS A  65
ASN A  67
ARG A  45
ASN A  79
TRP A  86
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
GAL  A 401 (-2.8A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
1.27A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		6 / 8HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
BGC  A 402 ( 2.5A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
BGC  A 402 ( 3.3A)
0.46A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		7 / 8HIS A 229
ASN A 231
ARG A 233
ASN A 242
TRP A 249
GLU A 252
ARG A 254
None
0.39A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4gqb PROTEIN ARGININE
N-METHYLTRANSFERASE
5
(Homo
sapiens)		4 / 8HIS A 549
ARG A 193
HIS A 190
GLU A 224
None
1.06A7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4oqa POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		4 / 8ASN C 767
ARG C 865
HIS C 909
GLU C 688
None
0.85A10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4xzp GALECTIN-4
(Homo
sapiens)		6 / 8HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
None
0.53A24.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		4y1y GALECTIN-1
(Homo
sapiens)		8 / 8HIS A  44
ASN A  46
ARG A  48
HIS A  52
ASN A  61
TRP A  68
GLU A  71
ARG A  73
GAL  A 201 (-3.9A)
GAL  A 201 (-4.4A)
6S2  A 202 (-2.8A)
GAL  A 201 (-4.2A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 4.1A)
6S2  A 202 (-2.6A)
6S2  A 202 (-3.8A)
0.36A78.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		4y26 GALECTIN-7
(Homo
sapiens)		7 / 8HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
ARG A  74
GAL  A 201 (-3.9A)
GAL  A 201 (-4.1A)
6S2  A 202 (-2.9A)
GAL  A 201 (-3.7A)
GAL  A 201 (-3.5A)
6S2  A 202 (-2.8A)
6S2  A 202 (-3.5A)
0.68A35.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4ym3 GALECTIN-4
(Homo
sapiens)		6 / 8HIS A 236
ASN A 238
ARG A 240
ASN A 249
TRP A 256
GLU A 259
LAT  A 401 (-3.9A)
LAT  A 401 (-4.0A)
LAT  A 401 (-2.6A)
LAT  A 401 (-3.7A)
LAT  A 401 ( 3.8A)
LAT  A 401 (-3.1A)
0.33A24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		4zwe DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
(Homo
sapiens)		4 / 8HIS A 210
ASN A 207
ARG A 206
GLU A 234
DGT  A 701 (-4.5A)
DGT  A 701 (-3.6A)
DGT  A 701 ( 4.2A)
None
1.13A8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5
(Homo
sapiens;
Homo
sapiens)		4 / 8HIS A 645
ARG A  15
HIS O 526
GLU A 611
None
1.14A4.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		5dux GALECTIN-4
(Homo
sapiens)		6 / 8HIS B  63
ASN B  65
ARG B  67
ASN B  77
TRP B  84
GLU B  87
LAT  B 201 (-3.9A)
LAT  B 201 (-3.8A)
LAT  B 201 (-2.6A)
LAT  B 201 (-3.9A)
LAT  B 201 ( 3.8A)
LAT  B 201 (-2.4A)
0.31A27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		5dux GALECTIN-4
(Homo
sapiens)		5 / 8HIS B  63
ASN B  77
TRP B  84
GLU B  87
ARG B  89
LAT  B 201 (-3.9A)
LAT  B 201 (-3.9A)
LAT  B 201 ( 3.8A)
LAT  B 201 (-2.4A)
LAT  B 201 ( 3.7A)
1.11A27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		5gzg GALECTIN-8
(Homo
sapiens)		6 / 8HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A 201 (-3.9A)
LAT  A 201 (-4.2A)
LAT  A 201 (-2.3A)
LAT  A 201 (-3.6A)
LAT  A 201 (-3.7A)
LAT  A 201 (-3.0A)
0.41A23.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		5h9p GALECTIN-3
(Homo
sapiens)		7 / 8HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
TD2  A 301 (-3.8A)
TD2  A 301 (-4.0A)
TD2  A 301 (-2.8A)
TD2  A 301 (-3.8A)
TD2  A 301 ( 3.7A)
TD2  A 301 (-2.9A)
TD2  A 301 (-3.9A)
0.45A32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		5nfb GALECTIN-3
(Homo
sapiens)		7 / 8HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
8VT  A 301 (-3.9A)
8VT  A 301 (-4.0A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.8A)
8VT  A 301 ( 3.7A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.4A)
0.48A37.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13
(Homo
sapiens)		4 / 8HIS A  53
HIS A  57
ASN A  65
GLU A  75
GOL  A 201 (-3.5A)
None
GOL  A 201 (-3.7A)
GOL  A 201 (-2.8A)
1.07A23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens)		4 / 8ARG C 186
ASN C 166
GLU C 165
ARG C 162
LAT  C 301 (-4.0A)
None
LAT  C 301 ( 4.7A)
LAT  C 301 (-2.7A)
1.16Aundetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens)		7 / 8HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
0.59Aundetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		1hlc HUMAN LECTIN
(Homo
sapiens)		7 / 10HIS A  45
ASN A  47
ARG A  49
ASN A  58
TRP A  65
GLU A  68
ARG A  70
GAL  A 998 (-3.8A)
GAL  A 998 (-4.1A)
BGC  A 999 ( 2.7A)
GAL  A 998 (-3.6A)
GAL  A 998 (-3.7A)
BGC  A 999 ( 2.8A)
BGC  A 999 (-4.3A)
0.50A30.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		2zhl GALECTIN-9
(Homo
sapiens)		7 / 10HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A1493 ( 3.9A)
GAL  A1493 (-3.6A)
NAG  A1494 ( 2.8A)
GAL  A1493 (-3.9A)
GAL  A1493 (-3.7A)
NAG  A1494 ( 2.7A)
NAG  A1494 (-4.0A)
0.43A32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		3ayd GALECTIN-3
(Homo
sapiens)		7 / 10HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
GAL  A 253 (-3.7A)
GAL  A 253 (-4.1A)
A2G  A 252 ( 3.1A)
GAL  A 253 (-3.9A)
GAL  A 253 (-3.5A)
A2G  A 252 (-3.0A)
GAL  A 256 ( 3.8A)
0.41A34.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		3nv3 GALECTIN 9 SHORT
ISOFORM VARIANT
(Homo
sapiens)		7 / 10HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 501 (-3.9A)
GAL  A 501 (-3.8A)
NAG  A 502 ( 2.7A)
GAL  A 501 (-3.8A)
GAL  A 501 (-3.6A)
NAG  A 502 ( 2.7A)
NAG  A 502 (-4.0A)
0.39A23.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		3ojb GALECTIN-8
(Homo
sapiens)		5 / 10HIS A  53
ASN A  55
ASN A  66
TRP A  73
ARG A  78
None
0.47A36.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 10HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
0.46A12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		3wv6 GALECTIN-9
(Homo
sapiens)		7 / 10HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
0.44A12.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		3zxe GALECTIN-7
(Homo
sapiens)		7 / 10HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
ARG A  74
PGZ  A   1 (-3.9A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-3.6A)
PGZ  A   1 (-3.8A)
PGZ  A   1 (-4.0A)
PGZ  A   1 (-3.5A)
None
0.63A38.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4bmb GALECTIN-8
(Homo
sapiens)		6 / 10HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A1155 (-3.9A)
LAT  A1155 (-3.9A)
LAT  A1155 (-2.7A)
LAT  A1155 (-3.9A)
LAT  A1155 (-3.6A)
LAT  A1155 (-3.0A)
0.41A29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		5 / 10HIS A  65
ASN A  67
ARG A  45
ASN A  79
TRP A  86
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
GAL  A 401 (-2.8A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
1.33A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		6 / 10HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
GAL  A 401 (-4.0A)
GAL  A 401 (-4.2A)
BGC  A 402 ( 2.5A)
GAL  A 401 (-3.8A)
GAL  A 401 (-3.5A)
BGC  A 402 ( 3.3A)
0.42A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4fqz GALECTIN-8
(Homo
sapiens)		7 / 10HIS A 229
ASN A 231
ARG A 233
ASN A 242
TRP A 249
GLU A 252
ARG A 254
None
0.48A16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4xzp GALECTIN-4
(Homo
sapiens)		6 / 10HIS A  63
ASN A  65
ARG A  67
ASN A  77
TRP A  84
GLU A  87
None
0.54A24.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		4y1y GALECTIN-1
(Homo
sapiens)		9 / 10HIS A  44
ASN A  46
ARG A  48
HIS A  52
ASP A  54
ASN A  61
TRP A  68
GLU A  71
ARG A  73
GAL  A 201 (-3.9A)
GAL  A 201 (-4.4A)
6S2  A 202 (-2.8A)
GAL  A 201 (-4.2A)
6S2  A 202 (-3.5A)
GAL  A 201 (-3.8A)
GAL  A 201 ( 4.1A)
6S2  A 202 (-2.6A)
6S2  A 202 (-3.8A)
0.44A78.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		4y26 GALECTIN-7
(Homo
sapiens)		7 / 10HIS A  49
ASN A  51
ARG A  53
ASN A  62
TRP A  69
GLU A  72
ARG A  74
GAL  A 201 (-3.9A)
GAL  A 201 (-4.1A)
6S2  A 202 (-2.9A)
GAL  A 201 (-3.7A)
GAL  A 201 (-3.5A)
6S2  A 202 (-2.8A)
6S2  A 202 (-3.5A)
0.71A35.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		4ym3 GALECTIN-4
(Homo
sapiens)		6 / 10HIS A 236
ASN A 238
ARG A 240
ASN A 249
TRP A 256
GLU A 259
LAT  A 401 (-3.9A)
LAT  A 401 (-4.0A)
LAT  A 401 (-2.6A)
LAT  A 401 (-3.7A)
LAT  A 401 ( 3.8A)
LAT  A 401 (-3.1A)
0.35A24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		5dux GALECTIN-4
(Homo
sapiens)		6 / 10HIS B  63
ASN B  65
ARG B  67
ASN B  77
TRP B  84
GLU B  87
LAT  B 201 (-3.9A)
LAT  B 201 (-3.8A)
LAT  B 201 (-2.6A)
LAT  B 201 (-3.9A)
LAT  B 201 ( 3.8A)
LAT  B 201 (-2.4A)
0.33A27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		5gzg GALECTIN-8
(Homo
sapiens)		6 / 10HIS A  65
ASN A  67
ARG A  69
ASN A  79
TRP A  86
GLU A  89
LAT  A 201 (-3.9A)
LAT  A 201 (-4.2A)
LAT  A 201 (-2.3A)
LAT  A 201 (-3.6A)
LAT  A 201 (-3.7A)
LAT  A 201 (-3.0A)
0.40A23.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		5h9p GALECTIN-3
(Homo
sapiens)		7 / 10HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
TD2  A 301 (-3.8A)
TD2  A 301 (-4.0A)
TD2  A 301 (-2.8A)
TD2  A 301 (-3.8A)
TD2  A 301 ( 3.7A)
TD2  A 301 (-2.9A)
TD2  A 301 (-3.9A)
0.38A32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		5nfb GALECTIN-3
(Homo
sapiens)		7 / 10HIS A 158
ASN A 160
ARG A 162
ASN A 174
TRP A 181
GLU A 184
ARG A 186
8VT  A 301 (-3.9A)
8VT  A 301 (-4.0A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.8A)
8VT  A 301 ( 3.7A)
8VT  A 301 (-2.7A)
8VT  A 301 (-3.4A)
0.34A37.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens)		7 / 10HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
0.45Aundetectable