POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		1ea6 PMS1 PROTEIN HOMOLOG
2
(Homo
sapiens)		4 / 8VAL A  43
TYR A 191
THR A  37
LEU A 188
None
0.97A20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		1ko6 NUCLEAR PORE COMPLEX
PROTEIN NUP98
(Homo
sapiens)		4 / 8VAL A 775
THR A 749
TYR A 724
LEU A 719
None
1.04A17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		1mi1 NEUROBEACHIN
(Homo
sapiens)		4 / 8LYS A2239
VAL A2240
THR A2164
LEU A2161
None
0.89A19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		1tf0 SERUM ALBUMIN
(Homo
sapiens)		4 / 8LYS A 414
VAL A 415
THR A 474
LEU A 460
None
1.00A21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1
(Homo
sapiens)		4 / 8VAL A 222
THR A 238
TYR A 271
LEU A 285
None
0.93A17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2id5 LEUCINE RICH REPEAT
NEURONAL 6A
(Homo
sapiens)		4 / 8ASP A 121
THR A 169
PRO A 168
LEU A 164
None
0.80A22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2jjd RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE EPSILON
(Homo
sapiens)		4 / 8VAL A 363
THR A 344
TYR A 388
LEU A 391
None
0.97A21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2n7g POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 2
(Homo
sapiens)		4 / 8VAL A  60
TYR A  70
THR A  67
LEU A 152
None
0.93A16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2pfi CHLORIDE CHANNEL
PROTEIN CLC-KA
(Homo
sapiens)		4 / 8LYS A 569
VAL A 570
TYR A 579
LEU A 558
None
1.02A17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2qtz METHIONINE SYNTHASE
REDUCTASE
(Homo
sapiens)		4 / 8VAL A 417
ASP A 419
PRO A 380
LEU A 385
None
1.02A20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2yf0 MYOTUBULARIN-RELATED
PROTEIN 6
(Homo
sapiens)		4 / 8VAL A 139
TYR A 192
TYR A 164
LEU A 189
None
0.84A20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3aqq CALCIUM-REGULATED
HEAT STABLE PROTEIN
1
(Homo
sapiens)		4 / 8VAL A 107
TYR A 109
THR A  80
LEU A  90
None
1.04A14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3k9o UBIQUITIN
(Homo
sapiens)		4 / 8LYS B  27
VAL B  26
ASP B  32
LEU B  56
None
0.80A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3n3k UBIQUITIN
(Homo
sapiens)		4 / 8LYS B  27
VAL B  26
ASP B  32
LEU B  56
None
0.74A13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3qfs NADPH--CYTOCHROME
P450 REDUCTASE
(Homo
sapiens)		4 / 8LYS A 621
THR A 529
PRO A 530
LEU A 564
None
0.86A21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3vdz UBIQUITIN-40S
RIBOSOMAL PROTEIN
S27A
(Homo
sapiens;
synthetic
construct)		4 / 8LYS A 127
VAL A 126
ASP A 132
LEU A 156
SO4  A 204 (-2.9A)
None
None
None
0.79A15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4c45 PTERIN-4-ALPHA-CARBI
NOLAMINE DEHYDRATASE
2
(Homo
sapiens)		4 / 8LYS A  92
VAL A  91
THR A  79
LEU A   9
None
1.04A14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4hfx TRANSCRIPTION
ELONGATION FACTOR B
POLYPEPTIDE 3
(Homo
sapiens)		4 / 8TYR A  64
THR A  19
PRO A  20
TYR A  24
None
0.95A12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		2mki CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 4
(Homo
sapiens)		4 / 5PRO A 153
VAL A  67
VAL A 121
ILE A 125
None
1.05A18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		3h2u RAVER-1
(Homo
sapiens)		4 / 5VAL B  75
ASN B  72
VAL B  98
ILE B  63
None
1.06A21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		3nwn KINESIN-LIKE PROTEIN
KIF9
(Homo
sapiens)		4 / 5VAL A 314
ASN A 316
VAL A  69
ILE A 115
None
1.06A20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		4xdo LYSINE-SPECIFIC
DEMETHYLASE 4C
(Homo
sapiens)		4 / 5VAL A 173
ASN A 292
VAL A 315
ILE A 317
None
1.02A21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		5bx1 PROTEIN TYROSINE
PHOSPHATASE TYPE IVA
1
(Homo
sapiens)		4 / 5PRO A 112
VAL A 115
VAL A  12
ILE A  21
SO4  A 202 (-4.5A)
None
None
None
0.97A15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		5dzz DESMOPLAKIN
(Homo
sapiens)		4 / 5PRO A2230
VAL A2233
ASN A2234
VAL A2219
None
1.04A23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		5f0k VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 35
(Homo
sapiens)		4 / 5VAL A 440
ASN A 443
VAL A 415
ILE A 460
None
1.08A21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		5gk9 BRD1 PROTEIN
HISTONE
ACETYLTRANSFERASE
KAT7
(Homo
sapiens)		4 / 5PRO A 552
VAL A 556
VAL B  40
ILE B  53
None
1.03A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		2f57 SERINE/THREONINE-PRO
TEIN KINASE PAK 7
(Homo
sapiens)		5 / 12VAL A 710
THR A 538
ILE A 574
VAL A 548
ILE A 545
None
1.37A21.40
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens)		5 / 12VAL A  16
THR A 109
PRO A 108
TYR A  99
ILE A  55
None
1.37A22.98
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3gov MASP-1
(Homo
sapiens)		5 / 12THR B 460
PRO B 461
PRO B 649
ILE B 684
VAL B 486
None
1.06A17.73
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		3num SERINE PROTEASE
HTRA1
(Homo
sapiens)		5 / 12THR A 293
ASN A 343
ILE A 342
VAL A 339
ILE A 179
None
1.41A18.78
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens)		5 / 12THR A  90
PRO A  87
ASN A  47
ILE A  46
VAL A  81
None
1.27A14.77
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4fie SERINE/THREONINE-PRO
TEIN KINASE PAK 4
(Homo
sapiens)		5 / 12VAL A 509
THR A 408
ILE A 581
VAL A 420
ILE A 446
None
1.26A22.91
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4fie SERINE/THREONINE-PRO
TEIN KINASE PAK 4
(Homo
sapiens)		5 / 12VAL A 582
THR A 410
ILE A 446
VAL A 420
ILE A 417
None
1.36A22.91
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4igd MANNAN-BINDING
LECTIN SERINE
PROTEASE 1
(Homo
sapiens)		5 / 12THR A 460
PRO A 461
PRO A 649
ILE A 684
VAL A 486
None
1.05A20.83
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		4xbr PROTEIN
FAM212A,SERINE/THREO
NINE-PROTEIN KINASE
PAK 4
(Homo
sapiens)		5 / 12VAL A 509
THR A 408
ILE A 581
VAL A 420
ILE A 446
None
1.19A22.15
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		5hgz N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens)		5 / 12VAL A  91
ILE A  77
LYS A  79
VAL A  95
ILE A  71
None
1.44A17.97
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		5vbn DNA POLYMERASE
EPSILON SUBUNIT 2
(Homo
sapiens)		5 / 12THR A 317
PRO A 316
PRO A 514
ILE A 497
VAL A 519
None
1.42A20.80
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		5vef SERINE/THREONINE-PRO
TEIN KINASE PAK 4
(Homo
sapiens)		5 / 12VAL A 509
THR A 408
ILE A 581
VAL A 420
ILE A 446
None
1.21A22.58
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		5xtd NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Homo
sapiens)		5 / 12THR J  62
PRO J  83
ILE J 152
VAL J 126
ILE J  81
NDP  J 401 (-3.0A)
None
None
None
None
1.31A21.77
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		6fn1 HUMAN-MOUSE CHIMERIC
ABCB1 (ABCBHM)
(Homo
sapiens)		5 / 12VAL A1034
THR A1064
ILE A1114
VAL A1079
ILE A1229
None
1.41A11.49
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		6gru ADP-SUGAR
PYROPHOSPHATASE
(Homo
sapiens)		5 / 12THR A 117
PRO A  66
ILE A 123
VAL A 144
ILE A  65
None
1.18A11.60
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		1bhq CD11B
(Homo
sapiens)		4 / 6LYS 1 187
ASP 1 134
PRO 1 193
LEU 1 198
None
1.30A19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		2c6y FORKHEAD BOX PROTEIN
K2
(Homo
sapiens)		4 / 6ASP A  44
PRO A   4
TYR A   8
LEU A  11
None
1.24A16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		3hig AMILORIDE-SENSITIVE
AMINE OXIDASE
(Homo
sapiens)		4 / 6LYS A 462
ASP A 466
TYR A 463
LEU A 378
TPQ  A 461 ( 3.4A)
None
TPQ  A 461 ( 4.5A)
None
1.32A21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens)		4 / 6ASP A 469
PRO A 446
TYR A 477
LEU A 464
None
1.32A21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA
(Homo
sapiens)		4 / 6LYS A 558
PRO A 565
TYR A 460
LEU A 563
None
1.34A17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		4a6e HYDROXYINDOLE
O-METHYLTRANSFERASE
(Homo
sapiens)		4 / 6LYS A  74
ASP A  65
PRO A  43
LEU A  37
SO4  A1353 (-3.2A)
None
None
None
1.28A20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Homo
sapiens)		4 / 6ASP A 171
PRO A 430
TYR A 433
LEU A 364
None
1.08A22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		5dqs ELONGATION FACTOR
1-GAMMA
(Homo
sapiens)		4 / 6ASP A 143
PRO A 178
TYR A 172
LEU A 209
None
1.10A17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		5epg ALDEHYDE OXIDASE
(Homo
sapiens)		4 / 6TYR A 898
PRO A1011
TYR A1164
LEU A 973
None
1.29A15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		5hly INHIBIN BETA A CHAIN
(Homo
sapiens)		4 / 6LYS A 134
ASP A 239
PRO A 291
LEU A 157
None
1.37A20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7
(Homo
sapiens)		4 / 6TYR A  33
PRO A 113
TYR A  38
LEU A  36
None
1.32A18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		6bf6 INSULIN-DEGRADING
ENZYME
(Homo
sapiens)		4 / 6LYS A 571
TYR A 634
PRO A 532
LEU A 616
None
1.33A12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		1jn5 TAP
(Homo
sapiens)		4 / 7VAL B 387
PHE B 479
VAL B 481
ILE B 483
None
0.59A18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		1n26 IL-6 RECEPTOR ALPHA
CHAIN
(Homo
sapiens)		4 / 7VAL A 217
ILE A 260
VAL A 271
ILE A 203
None
0.80A19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		1u2h AORTIC
PREFERENTIALLY
EXPRESSED PROTEIN 1
(Homo
sapiens)		4 / 7PRO A  20
VAL A  43
ILE A  41
VAL A  51
None
0.67A14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		1yxm PEROXISOMAL TRANS
2-ENOYL COA
REDUCTASE
(Homo
sapiens)		4 / 7VAL A 243
PHE A 103
VAL A 105
ILE A 157
None
0.80A23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		2bv5 TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 5
(Homo
sapiens)		4 / 7VAL A 454
PHE A 432
VAL A 372
ILE A 468
None
0.74A20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		2gwo DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13
(Homo
sapiens)		4 / 7VAL A 119
ILE A 123
VAL A  76
ILE A 102
None
0.72A19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		2mbg RALA-BINDING PROTEIN
1
(Homo
sapiens)		5 / 7PRO A 260
VAL A 220
ILE A 217
PHE A 213
ILE A 230
None
1.48A20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		3lpp SUCRASE-ISOMALTASE
(Homo
sapiens)		4 / 7ILE A 827
PHE A 842
VAL A 845
ILE A 847
None
0.77A18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		3n8e STRESS-70 PROTEIN,
MITOCHONDRIAL
(Homo
sapiens)		4 / 7VAL A 486
ILE A 447
VAL A 532
ILE A 547
None
0.67A18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		3nwn KINESIN-LIKE PROTEIN
KIF9
(Homo
sapiens)		4 / 7VAL A 123
ILE A 127
VAL A 137
ILE A 222
None
0.73A20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		1dhs DEOXYHYPUSINE
SYNTHASE
(Homo
sapiens)		5 / 12LEU A 107
VAL A 286
ILE A 290
ALA A 291
PHE A 100
NAD  A 700 (-4.6A)
None
None
None
None
0.80A21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		2zj4 GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING] 1
(Homo
sapiens)		5 / 12LEU A 419
ILE A 362
VAL A 443
GLY A 444
ILE A 445
None
0.73A21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		3lpp SUCRASE-ISOMALTASE
(Homo
sapiens)		5 / 12LEU A 881
ILE A 827
PHE A 842
VAL A 845
ILE A 847
None
0.78A18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		4g6j LIGHT CHAIN OF
ANTIBODY BINDING
FRAGMENT OF
CANAKINUMAB
(Homo
sapiens)		6 / 12LEU L  73
VAL L 104
ILE L 106
ALA L  80
VAL L  19
ILE L  21
None
1.45A20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		4hwi HEAT SHOCK COGNATE
71 KDA PROTEIN
(Homo
sapiens)		6 / 12VAL A 238
ASN A 239
ILE A 242
ALA A 243
LYS A 246
VAL A 260
None
1.11A22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		4pj1 60 KDA HEAT SHOCK
PROTEIN,
MITOCHONDRIAL
(Homo
sapiens)		5 / 12VAL A 124
ILE A 128
ALA A 129
LYS A 132
GLY A 510
None
0.69A23.06