POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		2h63 BILIVERDIN REDUCTASE
A
(Homo
sapiens)		4 / 7TYR A  98
GLU A 124
MET A 130
ILE A 250
NAP  A 501 (-3.6A)
NAP  A 501 ( 3.9A)
None
None
1.02A16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		3byh FIMBRIN ABD2
(Homo
sapiens)		4 / 7LEU B 405
TYR B 398
MET B 608
ILE B 611
None
1.08A16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		3c5n TUBBY-RELATED
PROTEIN 1
(Homo
sapiens)		4 / 7TYR A 448
LEU A 469
MET A 375
ILE A 406
None
1.18A15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae)		4 / 7GLU A 558
LEU A 272
TYR A 553
ILE A 521
None
1.03A10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		3mwe ATP-CITRATE SYNTHASE
(Homo
sapiens)		4 / 7TYR A 307
LEU A 338
MET A 391
ILE A 361
None
1.21A14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		3qfs NADPH--CYTOCHROME
P450 REDUCTASE
(Homo
sapiens)		4 / 7GLU A 581
LEU A 295
TYR A 576
ILE A 544
None
1.06A13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		4d4z DEOXYHYPUSINE
HYDROXYLASE
(Homo
sapiens)		4 / 7GLU A  93
HIS A  89
LEU A 204
MET A 179
GOL  A 305 (-2.7A)
FE  A 301 (-3.4A)
None
None
1.15A17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		4y07 NEDD4-LIKE E3
UBIQUITIN-PROTEIN
LIGASE WWP2
(Homo
sapiens)		4 / 7HIS A 618
LEU A 544
MET A 535
ILE A 532
None
1.08A13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		4zsl MITOGEN-ACTIVATED
PROTEIN KINASE 7
(Homo
sapiens)		4 / 7LEU A 234
TYR A 297
MET A 275
ILE A 274
None
1.07A13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
THE
ANAPHASE-PROMOTING
COMPLEX CHAIN R
(Homo
sapiens)		4 / 7TYR R  91
HIS A1231
LEU A1209
ILE A1193
None
0.98A12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		5m32 PROTEASOME SUBUNIT
BETA TYPE-2
(Homo
sapiens)		4 / 7TYR J 147
LEU J 115
TYR J  12
ILE J   5
None
1.12A20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		5tj7 NEDD4-LIKE E3
UBIQUITIN-PROTEIN
LIGASE WWP2
(Homo
sapiens)		4 / 7HIS A 618
LEU A 544
MET A 535
ILE A 532
None
1.02A13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1cyn PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
B
(Homo
sapiens)		4 / 6PHE A  30
PHE A  44
GLY A  72
GLY A  73
None
0.86A23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1p49 STERYL-SULFATASE
(Homo
sapiens)		4 / 6PHE A 473
GLY A 374
GLY A 375
ASN A 370
None
0.95A16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1zvd SMAD UBIQUITINATION
REGULATORY FACTOR 2
(Homo
sapiens)		4 / 6PHE A 508
PHE A 598
GLY A 487
GLY A 604
None
1.01A21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6PHE A 235
PHE A 237
GLY A 187
GLY A 214
None
0.99A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens)		4 / 6PHE A  25
PHE A  39
GLY A  75
GLY A  76
None
0.85A21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2wfi PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
G
(Homo
sapiens)		4 / 6PHE A  26
PHE A  40
GLY A  76
GLY A  77
None
None
OCS  A  63 ( 4.5A)
OCS  A  63 ( 3.2A)
0.80A24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2x25 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
A
(Homo
sapiens)		4 / 6PHE B  22
PHE B  36
GLY B  64
GLY B  65
None
0.90A22.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens)		4 / 6TRP A 105
GLY A 149
GLY A 150
ASN A 161
FAD  A 232 ( 4.3A)
FAD  A 232 (-3.6A)
FAD  A 232 (-3.6A)
None
0.18A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		4ap5 GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2
(Homo
sapiens)		4 / 6PHE A 108
TRP A 104
GLY A 365
GLY A 366
None
None
CL  A1432 (-4.2A)
None
0.95A20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		4pvg TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11
(Homo
sapiens)		4 / 6PHE A 469
TRP A 423
GLY A 434
GLY A 433
None
0.90A20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		5vei SORBIN AND SH3
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 6PHE A 874
PHE A 884
GLY A 910
GLY A 903
UNX  A1001 ( 4.6A)
None
None
None
0.97A17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1cyn PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
B
(Homo
sapiens)		4 / 5GLY A  72
GLY A  73
PHE A  30
PHE A  44
None
0.81A23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1y4j SULFATASE MODIFYING
FACTOR 2
(Homo
sapiens)		4 / 5TRP A 257
GLY A 203
PHE A  99
PHE A  96
None
1.02A20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1zvd SMAD UBIQUITINATION
REGULATORY FACTOR 2
(Homo
sapiens)		4 / 5GLY A 487
GLY A 604
PHE A 508
PHE A 598
None
1.06A21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5GLY A 187
GLY A 214
PHE A 235
PHE A 237
None
0.95A20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2he9 NK-TUMOR RECOGNITION
PROTEIN
(Homo
sapiens)		4 / 5GLY A  75
GLY A  76
PHE A  25
PHE A  39
None
0.78A21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2vsz ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens)		4 / 5TRP A 575
GLY A 559
PHE A 654
PHE A 562
None
1.06A19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2wfi PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
G
(Homo
sapiens)		4 / 5GLY A  76
GLY A  77
PHE A  26
PHE A  40
OCS  A  63 ( 4.5A)
OCS  A  63 ( 3.2A)
None
None
0.74A24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		2x25 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
A
(Homo
sapiens)		4 / 5GLY B  64
GLY B  65
PHE B  22
PHE B  36
None
0.84A22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		3orh GUANIDINOACETATE
N-METHYLTRANSFERASE
(Homo
sapiens)		4 / 5GLY A 163
GLY A 164
PHE A 157
PHE A 202
None
1.05A22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		3rc0 N-LYSINE
METHYLTRANSFERASE
SETD6
(Homo
sapiens)		4 / 5GLY A 106
GLY A 107
PHE A 203
PHE A 195
None
0.97A19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		4ap5 GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2
(Homo
sapiens)		4 / 5TRP A 104
GLY A 365
GLY A 366
PHE A 108
None
CL  A1432 (-4.2A)
None
None
0.91A20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		4pvg TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 11
(Homo
sapiens)		4 / 5TRP A 423
GLY A 434
GLY A 433
PHE A 469
None
0.93A20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		5vei SORBIN AND SH3
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)		4 / 5GLY A 910
GLY A 903
PHE A 874
PHE A 884
None
None
UNX  A1001 ( 4.6A)
None
1.04A17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 5ARG A 189
TYR A 327
TYR A 182
LEU A 328
None
1.42A17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens)		4 / 6ASN A 417
ARG A 422
TYR A 125
LEU A 116
None
1.49A16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		1n76 LACTOFERRIN
(Homo
sapiens)		4 / 6ASN A 640
ARG A 465
TYR A 435
TYR A 528
None
CO3  A 696 (-4.1A)
FE  A 694 ( 4.1A)
CO3  A 696 ( 4.2A)
1.40A14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		2r15 MYOMESIN-1
(Homo
sapiens)		4 / 6ASN A1495
ARG A1500
TYR A1529
LEU A1546
None
1.47A19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 6ARG A 189
TYR A 327
TYR A 182
LEU A 328
None
1.37A17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		4rou MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 3
(Homo
sapiens)		4 / 6TRP B 455
ASN B 412
ARG B 445
LEU B 426
None
1.36A16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5a1n AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 2
BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE
(Homo
sapiens)		4 / 6ASN A  52
ARG B 215
TYR A  68
LEU A 119
None
1.33A20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5ixd INTERFERON LAMBDA
RECEPTOR 1
TYROSINE-PROTEIN
KINASE JAK1
(Homo
sapiens)		4 / 6TRP B 257
ASN A 226
TYR A 217
LEU A 190
None
1.15A16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens)		4 / 7ARG A 422
TYR A 125
LEU A 116
ASN A 417
None
1.33A16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens)		4 / 7TYR B 453
LEU B 493
ASN B 497
TYR B 551
None
1.17A21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 7ARG A 189
TYR A 327
TYR A 182
LEU A 328
None
1.39A17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
8
(Homo
sapiens)		4 / 7TYR B 567
TYR B 571
LEU B 596
TYR B 511
None
1.12A13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5ixd INTERFERON LAMBDA
RECEPTOR 1
TYROSINE-PROTEIN
KINASE JAK1
(Homo
sapiens)		4 / 7TYR A 217
LEU A 190
TRP B 257
ASN A 226
None
1.24A13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
(Homo
sapiens)		4 / 7TYR A1172
TYR A1196
LEU A1176
ASN A1192
None
1.34A7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5mr4 GDNF FAMILY RECEPTOR
ALPHA-2
(Homo
sapiens)		4 / 7TYR C 181
LEU C 204
ASN C 308
TYR C 297
None
1.34A16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5w6m HISTIDINE--TRNA
LIGASE, CYTOPLASMIC
(Homo
sapiens)		4 / 7ARG A 149
TYR A 363
LEU A 366
TYR A 129
None
1.20A16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		4xnv P2Y PURINOCEPTOR 1,
RUBREDOXIN, P2Y
PURINOCEPTOR 1
(Clostridium
pasteurianum;
Homo
sapiens)		4 / 5ARG A 310
TYR A  58
TYR A 111
LEU A 107
None
1.13A16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		5t44 FRIZZLED-7
(Homo
sapiens)		4 / 5TRP A 112
ARG A 115
TYR A  76
LEU A  72
None
1.41A22.06