POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	3bpt	3-HYDROXYISOBUTYRYL- COA HYDROLASE (Homo sapiens)	5 / 12	GLY A 179 GLY A 180 LEU A 184 GLY A 149 VAL A 148	None	0.75A	22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	3kci	PROBABLE E3 UBIQUITIN-PROTEIN LIGASE HERC2 (Homo sapiens)	5 / 12	GLY A4012 ALA A4013 GLY A4015 GLY A4014 GLY A4021	None	0.86A	23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	4ccz	METHIONINE SYNTHASE (Homo sapiens)	5 / 12	ALA A 125 GLY A 123 LEU A 183 GLY A 187 VAL A 188	None	0.82A	22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	5hpk	E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE (Homo sapiens)	5 / 12	GLY A 698 ALA A 697 GLY A 694 MET A 804 LEU A 808	None	0.96A	21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	5 / 12	GLY A 638 GLY A 607 THR A 578 GLY A 359 VAL A 358	None	0.93A	19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O33_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	5vni	PROTEIN TRANSPORT PROTEIN SEC24A (Homo sapiens)	5 / 12	ALA B 786 GLY B 784 LEU B 410 LEU B 938 VAL B 930	None	0.94A	19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	2wfx	HEDGEHOG-INTERACTING PROTEIN (Homo sapiens)	5 / 12	ALA B 436 PHE B 554 PHE B 486 LEU B 491 GLY B 433	None None None None CA  B1670 ( 4.7A)	0.95A	20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	3kci	PROBABLE E3 UBIQUITIN-PROTEIN LIGASE HERC2 (Homo sapiens)	5 / 12	GLY A4012 ALA A4013 GLY A4015 GLY A4014 GLY A4021	None	0.78A	23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	4ccz	METHIONINE SYNTHASE (Homo sapiens)	5 / 12	ALA A 125 GLY A 123 LEU A 183 GLY A 187 VAL A 188	None	0.92A	23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	4fdd	TRANSPORTIN-1 (Homo sapiens)	5 / 12	GLY A 147 ALA A 148 GLY A 150 LEU A 152 GLY A 111	None	0.86A	20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	5hpk	E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE (Homo sapiens)	5 / 12	GLY A 698 ALA A 697 GLY A 694 MET A 804 LEU A 808	None	0.94A	21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O3F_A_TZNA501_1 (PHOSPHOGLYCERATE KINASE 1)	5nn8	LYSOSOMAL ALPHA-GLUCOSIDASE (Homo sapiens)	5 / 12	GLY A 638 GLY A 607 THR A 578 GLY A 359 VAL A 358	None	0.96A	18.31