POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 7	LEU A 302 PHE A 303 GLY A 306 THR A 310	HEM  A 600 ( 4.5A) None HEM  A 600 (-3.1A) HEM  A 600 (-4.0A)	0.58A	45.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	4 / 7	SER A 135 LEU A 302 GLY A 306 THR A 309	None HEM  A 600 ( 4.5A) HEM  A 600 (-3.1A) HEM  A 600 (-3.5A)	1.12A	45.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2jif	SHORT/BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE (Homo sapiens)	4 / 7	LEU A  97 PHE A  98 GLY A 101 THR A 114	None	1.00A	21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2nnj	CYTOCHROME P450 2C8 (Homo sapiens)	4 / 7	LEU A 294 PHE A 295 GLY A 298 THR A 302	HEM  A 500 ( 4.3A) None HEM  A 500 (-3.4A) HEM  A 500 (-4.2A)	0.49A	55.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	2pg6	CYTOCHROME P450 2A6 (Homo sapiens)	5 / 7	SER A 131 LEU A 298 GLY A 302 THR A 305 ILE A 366	None None HEM  A 500 (-3.5A) HEM  A 500 (-3.6A) HEM  A 500 ( 4.1A)	1.32A	55.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	3ctt	MALTASE-GLUCOAMYLASE (Homo sapiens)	4 / 7	LEU A 499 GLY A 501 THR A 525 ILE A 565	None	0.80A	20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	3ctz	XAA-PRO AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	SER A 479 LEU A 476 GLY A 450 ILE A 567	None	0.99A	22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	3lpp	SUCRASE-ISOMALTASE (Homo sapiens)	4 / 7	LEU A 528 GLY A 530 THR A 554 ILE A 594	None	0.81A	19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	3r92	HEAT SHOCK PROTEIN HSP 90-ALPHA (Homo sapiens)	4 / 7	SER A  52 LEU A  48 GLY A 137 ILE A  26	06J  A   1 ( 3.7A) None None None	1.08A	17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	3top	MALTASE-GLUCOAMYLASE , INTESTINAL (Homo sapiens)	4 / 7	LEU A1484 GLY A1486 THR A1509 ILE A1549	None	0.95A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	4qpm	MITOTIC CHECKPOINT SERINE/THREONINE-PRO TEIN KINASE BUB1 (Homo sapiens)	4 / 7	SER A 862 LEU A 864 GLY A 866 ILE A 924	None None None ADP  A1501 ( 4.5A)	1.05A	21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	4 / 7	LEU A 308 GLY A 312 THR A 315 ILE A 377	HEM  A 540 (-4.9A) HEM  A 540 ( 3.8A) HEM  A 540 (-3.6A) HEM  A 540 ( 3.9A)	0.98A	25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	5exr	DNA PRIMASE LARGE SUBUNIT (Homo sapiens)	4 / 7	SER B 352 LEU B 311 GLY B 315 ILE B 276	None	1.12A	21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	5lsu	HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 (Homo sapiens)	4 / 7	LEU A1163 PHE A1088 THR A1065 ILE A1067	None	0.86A	18.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	5wbg	CYTOCHROME P450 2B6 (Homo sapiens)	4 / 7	LEU A 295 PHE A 296 GLY A 299 THR A 303	HEM  A 501 ( 4.5A) None HEM  A 501 ( 3.9A) HEM  A 501 ( 4.6A)	0.65A	86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	5xxi	CYTOCHROME P450 2C9 (Homo sapiens)	4 / 7	LEU A 294 PHE A 295 GLY A 298 THR A 302	HEM  A 504 ( 4.7A) None HEM  A 504 (-3.4A) HEM  A 504 (-4.3A)	0.39A	51.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	6bwy	DU-EDITING ENZYME APOBEC-3G FUSION PROTECTION OF TELOMERES PROTEIN 1, DNA DC-> (Homo sapiens; Schizosaccharomy ces pombe)	4 / 7	LEU A  65 PHE A  47 GLY A  67 ILE A 118	None	1.01A	12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1b47	CBL (Homo sapiens)	5 / 12	LEU A  88 LEU A 151 THR A 152 LEU A 154 PHE A 158	None	0.81A	23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1b47	CBL (Homo sapiens)	5 / 12	LEU A  88 THR A 152 LEU A 154 SER A 155 PHE A 158	None	0.80A	23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1fbv	SIGNAL TRANSDUCTION PROTEIN CBL (Homo sapiens)	5 / 12	LEU A  88 LEU A 151 THR A 152 LEU A 154 PHE A 158	None	0.74A	23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1fbv	SIGNAL TRANSDUCTION PROTEIN CBL (Homo sapiens)	5 / 12	LEU A  88 THR A 152 LEU A 154 SER A 155 PHE A 158	None	0.71A	23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1jl0	S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME (Homo sapiens)	5 / 12	LEU A 180 ILE A 268 LEU A 177 THR A 176 LEU A 284	None None None PUT  A 401 (-3.7A) None	1.06A	21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1tki	TITIN (Homo sapiens)	5 / 12	ILE A 150 LEU A 209 THR A 208 LEU A 206 SER A 205	None	1.05A	20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1wy8	NP95-LIKE RING FINGER PROTEIN, ISOFORM A (Homo sapiens)	5 / 12	LEU A  52 ILE A  76 ILE A  10 LEU A  65 THR A  64	None	1.02A	11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	2wnt	RIBOSOMAL PROTEIN S6 KINASE (Homo sapiens)	5 / 12	LEU A 497 LEU A 498 LEU A 502 ILE A 501 LEU A 604	None	0.95A	21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	3ahr	ERO1-LIKE PROTEIN ALPHA (Homo sapiens)	5 / 12	LEU A  65 LEU A  68 LEU A 344 ILE A 347 ILE A 351	None	1.01A	22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	3ep7	S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN (Homo sapiens)	5 / 12	LEU A 180 ILE A 268 LEU A 177 THR A 176 LEU A 284	None	1.07A	19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	3k2j	PROTEIN POLYBROMO-1 (Homo sapiens)	5 / 12	PHE A 424 LEU A 398 LEU A 405 ILE A 401 LEU A 357	None	1.07A	12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	3vgo	E3 UBIQUITIN-PROTEIN LIGASE CBL-B (Homo sapiens)	5 / 12	LEU A  78 LEU A 143 THR A 144 LEU A 146 PHE A 150	None	0.89A	23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	4b18	IMPORTIN SUBUNIT ALPHA-1 (Homo sapiens)	5 / 12	LEU A 305 LEU A 317 ILE A 362 LEU A 347 LEU A 344	None	1.05A	21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	4eku	PROTEIN-TYROSINE KINASE 2-BETA (Homo sapiens)	5 / 12	LEU A 299 LEU A 279 ILE A 286 ILE A 348 LEU A 320	None	1.06A	20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	4uad	IMPORTIN SUBUNIT ALPHA-7 (Homo sapiens)	5 / 12	LEU A 303 LEU A 315 ILE A 360 LEU A 345 LEU A 342	None	1.04A	22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	5a1n	AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 (Homo sapiens)	5 / 12	PHE B 199 LEU B 112 LEU B 108 ILE B 122 LEU B 217	None	1.02A	18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	5vem	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 5 (Homo sapiens)	5 / 12	PHE A 359 LEU A 182 LEU A 184 ILE A 234 LEU A 373	None	1.05A	20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	5xbk	IMPORTIN-4 (Homo sapiens)	5 / 12	LEU D 989 LEU D 986 LEU D1023 ILE D1026 ILE D1030	None	0.94A	12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	1b4f	EPHB2 (Homo sapiens)	4 / 8	GLN A  60 LEU A  64 VAL A  52 LEU A  50	None	1.01A	12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	4 / 8	VAL A  64 LEU A  66 VAL A  69 VAL A  35	None	0.97A	21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	1mx3	C-TERMINAL BINDING PROTEIN 1 (Homo sapiens)	4 / 8	ARG A 192 LEU A 139 VAL A 262 VAL A 189	None	0.99A	22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2daz	INAD-LIKE PROTEIN (Homo sapiens)	4 / 8	LEU A  76 VAL A 103 LEU A  31 VAL A  55	None	1.02A	14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2e1f	WERNER SYNDROME ATP-DEPENDENT HELICASE (Homo sapiens)	4 / 8	LEU A1184 VAL A1218 LEU A1216 VAL A1198	None	0.72A	11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2e3l	TRANSCRIPTION FACTOR GTF2IRD2 BETA (Homo sapiens)	4 / 8	GLN A  41 MET A  37 LEU A  38 VAL A  46	None	0.94A	11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2g76	D-3-PHOSPHOGLYCERATE DEHYDROGENASE (Homo sapiens)	4 / 8	ARG A 162 LEU A 116 VAL A 231 VAL A 159	None	0.97A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2ggz	GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 (Homo sapiens)	4 / 8	LEU A  82 LEU A  98 VAL A  59 VAL A 177	None	1.02A	16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2gk1	BETA-HEXOSAMINIDASE SUBUNIT ALPHA (Homo sapiens)	4 / 8	GLN I 106 ARG I 252 VAL I 100 VAL A  60	None	0.94A	22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2ome	C-TERMINAL-BINDING PROTEIN 2 (Homo sapiens)	4 / 8	ARG A 198 LEU A 145 VAL A 268 VAL A 195	None	0.95A	21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2wz9	GLUTAREDOXIN-3 (Homo sapiens)	4 / 8	LEU A  26 VAL A  66 LEU A  68 VAL A  76	None	1.03A	14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	2ydy	METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA (Homo sapiens)	4 / 8	LEU A 295 VAL A 227 VAL A 179 VAL A 139	None	0.95A	21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	3apm	PROTEIN-ARGININE DEIMINASE TYPE-4 (Homo sapiens)	4 / 8	LEU A 254 VAL A 227 LEU A 229 VAL A 203	None	1.02A	21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	3byh	FIMBRIN ABD2 (Homo sapiens)	4 / 8	ARG B 419 LEU B 425 VAL B 459 VAL B 479	None	1.02A	17.58