POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	1z6t	APOPTOTIC PROTEASE ACTIVATING FACTOR 1 (Homo sapiens)	4 / 7	CYH A 480 TYR A 484 HIS A 468 TRP A 509	None	1.24A	18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	3zvz	E3 UBIQUITIN-PROTEIN LIGASE UHRF1 (Homo sapiens)	4 / 7	CYH B 336 CYH B 363 HIS B 319 TRP B 358	ZN  B 434 (-2.3A) ZN  B 434 (-2.3A) None None	1.50A	11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4cvh	ISOPRENOID SYNTHASE DOMAIN-CONTAINING PROTEIN (Homo sapiens)	4 / 7	CYH A 229 TYR A 226 TYR A 247 HIS A 127	None None None MG  A1452 (-4.2A)	1.40A	22.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4hxx	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	5 / 7	TYR A 195 CYH A 203 HIS A 212 HIS A 310 TRP A 353	1AY  A 405 (-4.3A) 1AY  A 405 ( 3.9A) CO  A 403 ( 3.3A) 1AY  A 405 (-3.4A) None	0.65A	45.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	CYH A 203 HIS A 212 HIS A 310 TRP A 353	FZ1  A 405 (-3.5A) CO  A 403 ( 3.1A) FZ1  A 405 (-3.4A) None	0.73A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	TYR A 195 CYH A 203 HIS A 212 HIS A 310	FZ1  A 405 (-4.4A) FZ1  A 405 (-3.5A) CO  A 403 ( 3.1A) FZ1  A 405 (-3.4A)	0.44A	33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	1g1c	IMMUNOGLOBULIN-LIKE DOMAIN I1 FROM TITIN (Homo sapiens)	4 / 8	ILE A   8 TRP A  39 SER A  90 ILE A  12	None	1.10A	19.56 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	1kwa	HCASK/LIN-2 PROTEIN (Homo sapiens)	4 / 8	HIS A 512 ILE A 514 ILE A 536 ARG A 537	None	0.97A	15.66 23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	1oww	FIBRONECTIN FIRST TYPE III MODULE (Homo sapiens)	4 / 8	PRO A  25 HIS A  29 ILE A  30 SER A  75	None	1.11A	16.74 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	2a9j	BISPHOSPHOGLYCERATE MUTASE (Homo sapiens)	4 / 8	PRO A 213 ILE A 245 ILE A 210 ARG A 117	None None None 3PG  A 408 (-2.8A)	0.91A	20.65 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	2if7	SLAM FAMILY MEMBER 6 (Homo sapiens)	4 / 8	PRO A  51 HIS A  54 ILE A  53 ILE A  31	None	0.94A	16.41 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	4p7h	MYOSIN-7,GREEN FLUORESCENT PROTEIN (Aequorea victoria; Homo sapiens)	4 / 8	HIS A 284 ILE A 285 ILE A 313 ARG A 281	None	1.07A	13.52 9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFE_C_TMGC1_1 (SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL)	5k1b	WD REPEAT-CONTAINING PROTEIN 48 (Homo sapiens)	4 / 8	PRO B 514 HIS B  73 SER B  52 ILE B  53	None	0.95A	13.93 12.73